Clinical trials: DWI
Renal Cell Carcinoma
MRI in Renal Tumors
Diagnostic imaging for renal masses of unknown nature using conventional imaging modalities such as 3 phase contrast-enhanced computed tomography (CT) is not always conclusive.
- Trial name
- NCT02325921
- Testing
- Magnetic Resonance Imaging
- Where
- Netherlands
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Stroke
CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase
To select the best dosage of tenecteplase for acute ischemic stroke patients (onset time 4.5-24h) of large vessel occlusion using early combined CT/MR imaging outcomes
- Trial name
- CHABLIS-T (NCT04086147)
- Testing
- Low dose tenecteplase, High dose tenecteplase
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Huashan Hospital
Brain Ischemia, Postoperative Confusion
Impact of Remote Ischemic Preconditioning Preceding Coronary Artery Bypass Grafting on Inducing nEuroprotection
Coronary artery disease (CAD) is the leading cause of death worldwide. Patients with severe CAD are often treated with coronary artery bypass grafting (CABG).
- Trial name
- RIPCAGE (NCT02177981)
- Testing
- Remote ischemic preconditioning, Control
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- University of Zagreb
Screening Breast MRI in Patients Who Are BRCA Mutation Carriers
Rapid Pancreatic and Ovarian Screening MR Imaging With Motion Corrected T1, T2, and Advanced Diffusion Weighted Imaging for Patients With BRCA Mutation Who Undergo Screening Breast MRI
The purpose of this study is to create a rapid scan of the pancreas and ovaries that could be used in the future to screen patients at risk for pancreatic or ovarian cancers.
- Trial name
- NCT02462460
- Testing
- MRI, Optional Screening Questionnaire
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Transportation Accidents, Drunk Driving
Design and Implementation of a Drunk Driving Detection System
To analyse driving behavior of individuals under the influence of alcohol using a validated research driving simulator. Based on the driving variables provided by the simulator the investigators aim at establishing algorithms…
- Conditions
- Transportation Accidents, Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT04980846)
- Testing
- Driving under the influence of alcohol with a driving simulator
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bern
Pancreatic Ductal Adenocarcinoma
MRI Effects of Pegvorhyaluronidase Alfa (PEGPH20) in Pancreatic Ductal Adenocarcinoma
This research study is being conducted to determine the effects of PEGPH20 plus chemotherapy treatment on the MRI characteristics of locally advanced pancreatic cancer patient tumors.
- Trial name
- NCT04134468
- Testing
- Pegvorhyaluronidase alfa, Abraxane, Gemcitabine
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Carotid Stenosis, Carotid Artery Diseases
The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study
The goal of this study is to evaluate the incidence of post procedure DW-MRI lesions (relative to baseline) and debris captured in the ENROUTE Transcarotid NPS inline filter during a transcarotid stenting procedure.
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Carotid Atherosclerosis, Carotid Artery Plaque
- Trial name
- DW-MRI OUS (NCT03985774)
- Testing
- Transcarotid revascularization
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 31 people
- Sponsor
- Silk Road Medical
Multiple Myeloma
Comparison Between Whole Body DWI and FDG PET/CT in Patients with Simptomatic Multiple Myeloma
The primary objective is to evaluate the concordance of FDG PET/CT and total body DWI MRI sequences performed during staging and at the completion of therapy.
- Trial name
- MMR-PET-22-04 (NCT06659276)
- Where
- Italy
- Volunteers
- 83 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Lung Neoplasms
Application of Diffusion Weighted MRI Versus CT in Evaluation of the Effect of Treating Lung Cancer
The purpose of this study is to investigate the diagnostic accuracy of ADC value of diffusion weighted MRI in comparison of conventional treatment assessment criteria in evaluation of chemotherapy.
- Trial name
- NCT02320617
- Testing
- Diffusion Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Air Force Military Medical University, China
Cancer
Apparent Diffusion Coefficient as a Prognostic Biomarker in Cervical Cancer
This study aims to develop the technique of Diffusion-Weighted Magnetic Resonance Imaging(DW-MRI)for the assessment of stage 1 cervical cancers.
- Trial name
- NCT01937533
- Testing
- Magnetic Resonance Imaging using an endovaginal receiver coil
- Where
- United Kingdom
- Volunteers
- 236 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Driving Under the Influence
Whole Blood-plasma-oral Fluid Ratios of Psychoactive Drugs and Medicines
The aim of this study is to get new information on the whole blood-plasma-oral fluid ratios of psychoactive drugs which are encountered in traffic.
- Trial name
- NCT00650130
- Where
- Finland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Gastric Adenocarcinoma
Diffusion Weighted Magnetic Resonance Imaging for Preoperative Staging in Gastric Adenocarcinoma Patients
Preoperative staging for gastric adenocarcinoma is an important procedure to detect advanced disease stateS for the patients in which the surgery may be unnecessary to perform.
- Trial name
- NCT01794026
- Testing
- diffusion weighted magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Cerebrovascular Accident
Diffusion Weighted Imaging Evaluation for Understanding Stroke Evolution Study-2 (DEFUSE-2)
Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution Study 2 (DEFUSE 2) is a multi-center pilot study to determine if cerebral perfusion imaging can help identify which patients, who are ineligible for…
- Trial name
- NCT01349946
- Where
- 7 sites in United States
- Volunteers
- 138 people
- Sponsor
- Stanford University
Acute Stroke, Acute Cerebral Ischemia
Efficacy and Safety of Continuous Intravenous Versus Usual Subcutaneous Insulin in Acute Ischemic Stroke
Hyperglycaemia is a frequent finding in acute ischemic stroke and associated with poor outcome. But the modalities of glucose lowering are still debated.
- Trial name
- INSULINFARCT (NCT00472381)
- Testing
- Insulin
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Undetermined Ovarian Mass
Characterization of Ovarian Masses Unable to Classify With Gynecological Ultrasonography: Value of Pelvic MRI With Perfusion- and Diffusion-weighted Imaging
The aim of the study is to prospectively evaluate the value of pelvic MRI including diffusion- and perfusion-weighted sequences in the selected group of patients that have an undetermined ovarian mass at ultrasound.
- Trial name
- IOTAMRI (NCT02425540)
- Testing
- Pelvic MRI
- Where
- Belgium
- Volunteers
- 74 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gastro-intestinal Tumor, Accurate Staging
Whole Body Diffusion MRI for Non-invasive Lesion Detection and Therapy Follow-up: Study With Patients With Gastro-intestinal Tumors
The aim of the study is to assess the value of whole body diffusion weighted MR imaging (WB-DWI) as a non-invasive method. On one hand for pretreatment lesion detection and post-therapeutic tumor recurrence but also for early…
- Conditions
- Gastro-intestinal Tumor, Accurate Staging, Whole-body Diffusion Weighted MRI, Non-invasive
- Trial name
- s51240 (NCT01224990)
- Testing
- Whole body diffusion MRI
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Prostate Cancer, Benign Prostatic Hyperplasia
Application of DWI in Diagnosis of Prostate Cancer
This study compared the performance of different models of multiple b-value DWI in diagnosing prostate cancer.
- Trial name
- NCT04962269
- Testing
- MRI
- Volunteers
- 103 people
- Sponsor
- Peking University Third Hospital
Pelvic Diseases, Abdominal Diseases
The Study of Functional Magnetic Resonance Imaging in Abdominal and Pelvic Diseases
The purpose of this study is to study the diagnostic efficiency of functional magnetic resonance imaging in Abdominal and Pelvic Diseases.
- Trial name
- NCT02337777
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Arthritis, Juvenile Idiopathic, Enthesitis-Related Arthritis, Juvenile
Juvenile Arthritis Quantitative Imaging
This observational study aims to develop and validate quantitative magnetic resonance imaging biomarkers as measures of disease activity in juvenile idiopathic arthritis (JIA).
- Trial name
- JAQI (NCT02684695)
- Testing
- MRI scan (adolescent spine protocol), MRI scan (whole body protocol)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Breast Cancer
Diffusion Weighted MRI for Lymphnodes in the Axilla
This study is going to compare diffusionweigthed MRI scanning to the result of surgey in patients with metastasis from brestcancer in the axilla
- Trial name
- NCT00276211
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital at Herlev