Clinical trials: DWI-MRI
Soft Tissue Neoplasms, Gastrointestinal Tract
Treatment Response Evaluation in Gastrointestinal Stromal Tumor (GIST) Patients
The purpose of this study is to compare sensitivity, specificity and accuracy of PET, DW MRI and CT separately and combined for the evaluation of treatment response and progression-free survival in patients with GIST.
- Trial name
- NCT01276483
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
MIBC, mpMRI
Early Prediction of Neoadjuvant Chemotherapy Response in Bladder Cancer Using Quantitative Multiparametric MRI
Bladder cancer is a prevalent malignancy globally, with muscle-invasive disease having a five-year survival rate below 50%. Neoadjuvant chemotherapy (NAC) before radical cystectomy has shown efficacy for resectable…
- Conditions
- MIBC, mpMRI, NAC
- Trial name
- mpMRI (NCT07202845)
- Testing
- Multiparametric Magnetic Resonance Imaging (mpMRI)
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Assiut University
Radiotherapy, Brain Metastases
Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases
Stereotactic radiation therapy is an important and common method of treating brain metastases in patients with malignant disease.
- Conditions
- Radiotherapy, Brain Metastases, Sensitivity, Radionecrosis
- Trial name
- NCT04700748
- Testing
- Brain metastases radiation
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University Hospital
Ovarian Cancer, Recurrent Ovarian Carcinoma
A New Fast DWI-based MR Protocol for Surveillance in Patients With a High Risk of Ovarian Cancer Recurrence During PARP-inhibitors Maintenance to Enhance Secondary Cytoreduction Results
In ovarian cancer (OC), complete surgical debulking and platinum-based chemotherapy are the standard treatment, now followed by maintenance therapy with PARP inhibitors or Bevacizumab.
- Trial name
- FOFU (NCT06541171)
- Testing
- Magnetic resonance imaging as fpr clinical practice
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rectal Adenocarcinoma
Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems
feasibility of using a diffusion sequence of a MRgRT system as an early marker of treatment response during nRCT of rectal adenocarcinoma.
- Trial name
- DWI_RECT_MRGRT (NCT03961776)
- Testing
- MRI-guided radiotherapy by on-board DWI sequences
- Where
- 2 sites in United States, France
- Volunteers
- 39 people
- Sponsor
- Institut Paoli-Calmettes
Ovarian Cancer, Peritoneal Metastases
Diffusion-weighted Imaging Study in Cancer of the Ovary
This project seeks to develop a quantitative imaging biomarker for evaluating and monitoring treatment response in ovarian cancer metastases and assess its potential in monitoring treatment response.
- Trial name
- DISCOVAR (NCT01505829)
- Where
- 6 sites in United Kingdom
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Prostate Cancer
WB-DW-MRI vs CHOLINE-PET/CT for Selecting Treatments in Recurrent Prostate Cancer
The purpose of this study is to determine the effectiveness of whole-body diffusion-weighted magnetic resonance imaging (WB-DW- MRI) in detecting metastases by comparing the results with those from choline-positron emission…
- Trial name
- NCT02858128
- Testing
- IMAGING STUDY
- Volunteers
- 46 people
- Sponsor
- Hospital Provincial de Castellon
Stroke, Acute
ERILs Und SNILs Unter SOC
1. How many ERILs occur in caucasian patients with LAA stroke during 7 days on standard treatment? 2. How many SNILs occur between 7 and 30 days after acute ischemic event on standard treatment? 3.
- Trial name
- NCT05786170
- Testing
- diffusion-weighted magnetic resonance imaging
- Sponsor
- Medical University of Vienna
Locally Advanced Rectal Carcinoma, Neoadjuvant Treatment
Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer
This pilot study aims to trial multimodal early response assessment to enable therapy adaptions in the context of non-operative therapy strategies of locally advanced rectal cancer (LARC) for development of a non-invasive…
- Conditions
- Locally Advanced Rectal Carcinoma, Neoadjuvant Treatment, Radiotherapy, Adaptive Treatment
- Trial name
- PRIMO (NCT05524012)
- Testing
- Blood sample, MRI scan
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Jena University Hospital
Distant Metastasis
Comparison Study Between PET/CT and Whole-Body Diffusion Weighted MRI in the Detection of Distant Malignancies
The purpose of the study is to compare the efficacy of 18F-FDG PET/CT and DWI WB-MRI in detection of distant metastasis of various cancers.
- Trial name
- NCT06205901
- Testing
- PET-CT, MRI
- Volunteers
- 50 people
- Sponsor
- Sohag University
Renal Cell Carcinoma
MRI in Renal Tumors
Diagnostic imaging for renal masses of unknown nature using conventional imaging modalities such as 3 phase contrast-enhanced computed tomography (CT) is not always conclusive.
- Trial name
- NCT02325921
- Testing
- Magnetic Resonance Imaging
- Where
- Netherlands
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Stroke
CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase
To select the best dosage of tenecteplase for acute ischemic stroke patients (onset time 4.5-24h) of large vessel occlusion using early combined CT/MR imaging outcomes
- Trial name
- CHABLIS-T (NCT04086147)
- Testing
- Low dose tenecteplase, High dose tenecteplase
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Huashan Hospital
Brain Ischemia, Postoperative Confusion
Impact of Remote Ischemic Preconditioning Preceding Coronary Artery Bypass Grafting on Inducing nEuroprotection
Coronary artery disease (CAD) is the leading cause of death worldwide. Patients with severe CAD are often treated with coronary artery bypass grafting (CABG).
- Trial name
- RIPCAGE (NCT02177981)
- Testing
- Remote ischemic preconditioning, Control
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- University of Zagreb
Screening Breast MRI in Patients Who Are BRCA Mutation Carriers
Rapid Pancreatic and Ovarian Screening MR Imaging With Motion Corrected T1, T2, and Advanced Diffusion Weighted Imaging for Patients With BRCA Mutation Who Undergo Screening Breast MRI
The purpose of this study is to create a rapid scan of the pancreas and ovaries that could be used in the future to screen patients at risk for pancreatic or ovarian cancers.
- Trial name
- NCT02462460
- Testing
- MRI, Optional Screening Questionnaire
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pancreatic Ductal Adenocarcinoma
MRI Effects of Pegvorhyaluronidase Alfa (PEGPH20) in Pancreatic Ductal Adenocarcinoma
This research study is being conducted to determine the effects of PEGPH20 plus chemotherapy treatment on the MRI characteristics of locally advanced pancreatic cancer patient tumors.
- Trial name
- NCT04134468
- Testing
- Pegvorhyaluronidase alfa, Abraxane, Gemcitabine
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Carotid Stenosis, Carotid Artery Diseases
The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study
The goal of this study is to evaluate the incidence of post procedure DW-MRI lesions (relative to baseline) and debris captured in the ENROUTE Transcarotid NPS inline filter during a transcarotid stenting procedure.
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Carotid Atherosclerosis, Carotid Artery Plaque
- Trial name
- DW-MRI OUS (NCT03985774)
- Testing
- Transcarotid revascularization
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 31 people
- Sponsor
- Silk Road Medical
Multiple Myeloma
Comparison Between Whole Body DWI and FDG PET/CT in Patients with Simptomatic Multiple Myeloma
The primary objective is to evaluate the concordance of FDG PET/CT and total body DWI MRI sequences performed during staging and at the completion of therapy.
- Trial name
- MMR-PET-22-04 (NCT06659276)
- Where
- Italy
- Volunteers
- 83 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Lung Neoplasms
Application of Diffusion Weighted MRI Versus CT in Evaluation of the Effect of Treating Lung Cancer
The purpose of this study is to investigate the diagnostic accuracy of ADC value of diffusion weighted MRI in comparison of conventional treatment assessment criteria in evaluation of chemotherapy.
- Trial name
- NCT02320617
- Testing
- Diffusion Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Air Force Military Medical University, China
Cancer
Apparent Diffusion Coefficient as a Prognostic Biomarker in Cervical Cancer
This study aims to develop the technique of Diffusion-Weighted Magnetic Resonance Imaging(DW-MRI)for the assessment of stage 1 cervical cancers.
- Trial name
- NCT01937533
- Testing
- Magnetic Resonance Imaging using an endovaginal receiver coil
- Where
- United Kingdom
- Volunteers
- 236 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Gastric Adenocarcinoma
Diffusion Weighted Magnetic Resonance Imaging for Preoperative Staging in Gastric Adenocarcinoma Patients
Preoperative staging for gastric adenocarcinoma is an important procedure to detect advanced disease stateS for the patients in which the surgery may be unnecessary to perform.
- Trial name
- NCT01794026
- Testing
- diffusion weighted magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University