Clinical trials: DWI-MRI
Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone
18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma
This pilot trial studies fluorine F 18 fluorothymidine (18F-FLT) positron emission tomography and diffusion-weighted magnetic resonance imaging in planing surgery and radiation therapy and measuring response in patients with…
- Conditions
- Adult Supratentorial Primitive Neuroectodermal Tumor (PNET), Ewing Sarcoma of Bone, Extraosseous Ewing Sarcoma, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Trial name
- NCT01825902
- Testing
- fluorine F 18 fluorothymidine, fludeoxyglucose F 18, positron emission tomography
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Pancreatic Ductal Adenocarcinoma
MRI Effects of Pegvorhyaluronidase Alfa (PEGPH20) in Pancreatic Ductal Adenocarcinoma
This research study is being conducted to determine the effects of PEGPH20 plus chemotherapy treatment on the MRI characteristics of locally advanced pancreatic cancer patient tumors.
- Trial name
- NCT04134468
- Testing
- Pegvorhyaluronidase alfa, Abraxane, Gemcitabine
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Crohn Disease, Bowel Cleansing
DWI MR-enterography Without or With Bowel Cleansing to Assess Intestinal Inflammatory Activity in the Follow-up of Crohn's Disease
Since 2009, many studies tend to prove the effectiveness of diffusion-weighted MR-enterography in the assessment of inflammatory activity in IBD compared to standard MR-enterography, with the emergence of new radiological scores…
- Conditions
- Crohn Disease, Bowel Cleansing, Apparent Diffusion Coefficient
- Trial name
- ENTEDIF (NCT05354609)
- Testing
- MR-enterography
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Ischemic Stroke
The Correlation Between Outcome and Infarct Growth in Patients With Acute Ischemic Stroke
Previous research has shown there wasn't inevitable relationship between mismatch area and infarct growth according to Volumetric-subtraction mismatch volume.The recently published on Stroke paper has proposed Coregistration…
- Trial name
- COIG (NCT01376609)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Renal Cell Carcinoma
MRI in Renal Tumors
Diagnostic imaging for renal masses of unknown nature using conventional imaging modalities such as 3 phase contrast-enhanced computed tomography (CT) is not always conclusive.
- Trial name
- NCT02325921
- Testing
- Magnetic Resonance Imaging
- Where
- Netherlands
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Prostatic Neoplasms, Genital Neoplasms, Male
High Resolution, 18F-PSMA PET-MRI Before Prostate Cancer HIFU or Radical Prostatectomy
This prospective trial aims to determine if enhanced prostate imaging using two novel imaging technologies (high resolution DWI and 18F-PSMA PET-MRI) will detect prostate cancers not seen on standard multiparametric prostate MRI…
- Conditions
- Prostatic Neoplasms, Genital Neoplasms, Male, Urogenital Neoplasms, Neoplasms by Site
- Trial name
- NCT04461509
- Testing
- 18F-PSMA
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Alessandro D'Agnolo
Breast Neoplasms, Artificial Intelligence (AI)
Non-Contrast Breast MRI Diagnosis and Risk Stratification Using DWI-Generated Synthetic Contrast Enhancement
This study is conducted under the ethics-approved project titled "Artificial Intelligence Solution for Simplifying the Diagnostic Workflow of Breast MRI''.The goal of this observational study is to develop an integrated breast…
- Conditions
- Breast Neoplasms, Artificial Intelligence (AI), Magnetic Resonance Imaging (MRI), Diffusion Magnetic Resonance Imaging
- Trial name
- NCT07598084
- Testing
- Non-contrast breast MRI diagnostic model
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Ischemic Optic Neuropathy, Optic Neuritis
Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.
The aim of the project is to create a new, non-invasive and safe protocol for the early diagnosis of various types of optic neuropathies with the use of diffusion magnetic resonance imaging
- Conditions
- Ischemic Optic Neuropathy, Optic Neuritis, Compressive Optic Neuropathy, Traumatic Optic Neuropathy
- Trial name
- NCT05353413
- Testing
- Neuroimaging, VEP - visual evoked potential, Ophthalmology examination.
- Where
- Poland
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Hereditary Clear Cell Renal Cell Carcinoma, Kidney Cancer
Sorafenib in Treating Patients With Locally Advanced or Metastatic Kidney Cancer
RATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00727532
- Testing
- Sorafenib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Northwestern University
Acute Stroke, Acute Cerebral Ischemia
Efficacy and Safety of Continuous Intravenous Versus Usual Subcutaneous Insulin in Acute Ischemic Stroke
Hyperglycaemia is a frequent finding in acute ischemic stroke and associated with poor outcome. But the modalities of glucose lowering are still debated.
- Trial name
- INSULINFARCT (NCT00472381)
- Testing
- Insulin
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Metastases, Hepatocarcinoma
Use of DwI-MR to Predict Chemotherapy Response of Liver Metastases and Hepatocarcinoma
One of the most recent and interesting field of diagnostic imaging is diffusion-weighted MR imaging (DW-MRI). Various studies evaluated the application of DW-MRI to diffuse liver disease and focal liver lesions providing…
- Trial name
- NCT01411579
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Stefano Colagrande
Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer
Diffusion-weighted MRI for Individualized Radiation Therapy Planning of Lung Cancer
This clinical trial studies diffusion-weighted magnetic resonance imaging (MRI) in identifying and localizing tumors in patients with non-small cell lung cancer undergoing radiation therapy.
- Conditions
- Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lung Cancer, Stage IIIA Non-small Cell Lung Cancer
- Trial name
- NCT02059889
- Testing
- diffusion-weighted magnetic resonance imaging, 4-dimensional computed tomography, fludeoxyglucose F 18
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Uterine Neoplasms
MRI and Metabolomics Biomarkers for Uterine Malignancy
The aims of this project are: (1) To establish a research platform in order to integrate multiparametric imaging and metabolomics data for uterine malignancy.
- Trial name
- EMCAMRS (NCT02528864)
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer
Diffusion Weighted Magnetic Resonance Imaging of the Breast During Chemotherapy: Response Evaluation
Evaluation of the response to chemotherapy in breast cancer patients by the use of Diffusion-weighted magnetic resonance imaging of the breast before the start of chemotherapy, after one and 3 cycles of therapy and at the end of…
- Trial name
- NCT01684735
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cholesteatoma
Usefulness of Non EPI-DWI-MRI / CT 3D Static Co-registration Prior to Surgery of Cholesteatomas
Cholesteatoma is a destructive and expanding pathologic condition consisting of keratin pearl arising from a squamous epithelium in the middle ear and/or mastoid process.
- Trial name
- NCT02903550
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Carotid Artery Stenosis
Impact of Aspiration Thrombectomy During Carotid Stenting
The purpose of this study is to determine whether aspiration thrombectomy following carotid stent deployment will reduce the number of procedure related signals as identified by diffusion weighted MRI of the brain.
- Trial name
- NCT01550835
- Testing
- Emboshield NAV6® embolic protection system (Abbott Vascular, Santa Clara, CA)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Fogarty Clinical Research Inc.
Silent Stroke, Pulmonary Embolism
Risk of Stroke in Pulmonary Embolism With a Patent Foramen Ovale (PFO)
Pulmonary embolism is associated with a small but definite risk of paradoxical embolism in patients with a patent foramen ovale (PFO).
- Conditions
- Silent Stroke, Pulmonary Embolism, Patent Foramen Ovale
- Trial name
- ICEP (NCT00831259)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Caen
Thyroid Cancer, Relapse
Comparison DW-MRI vs FDG PET/CT in the Detection of Early Recurrence of Cervical Well-differentiated Thyroid Carcinoma
The purpose of the study is to evaluate the concordance between the 18F-PET/CT under thyrotropin stimulation and the diffusion-weighted Magnetic Resonance Imaging, in the detection of residual mass in 40 patients with partial…
- Trial name
- THYRIRMTEP (NCT02515084)
- Testing
- PET, MRI imaging
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Henri Becquerel
Osteosarcoma
Diffusion Study on Patients With Osteosarcoma
The aim of the study is to assess the accuracy of dynamic contrast enhanced and diffusion-weighted MR Imaging in evaluating response to chemotherapy in osteosarcoma.
- Trial name
- NCT01615640
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Klinikum Stuttgart
Pancreatic Adenocarcinoma
Diffusion MRI for Pancreatic Adenocarcinoma
The detection of small liver metastases represents a major challenge during the staging process of patients with pancreatic adenocarcinoma.
- Trial name
- PANDA (NCT02896946)
- Testing
- Diffusion-weighted nuclear magnetic resonance imaging
- Volunteers
- 118 people
- Sponsor
- Hospices Civils de Lyon