Clinical trials: Dalteparin
Distal (Calf) Deep-vein Thrombosis
Randomized Controlled Trial of Anticoagulation vs. Placebo for a First Symptomatic Isolated Distal Deep-vein Thrombosis (IDDVT)
CACTUS-PTS is a randomized, placebo-controlled, double-blind study which aims primarily to determine the effectiveness of a 6 week course of therapeutic-dose LMWH (nadroparine) injections vs.
- Trial name
- CACTUS-PTS (NCT00421538)
- Testing
- nadroparine calcium
- Where
- 7 sites in Canada, France and 1 more
- Volunteers
- 260 people
- Sponsor
- University Hospital, Geneva
Retinal Detachment, Proliferative Vitreoretinopathy
Efficacy of 5-fluorouracil and Low Molecular Weight Heparin in High-risk Pediatric Retinal Detachment
EVALUATION OF 5-FLOUROURACIL AND LOW MOLECULAR WEIGHT HEPARIN INTRAOPERATIVE INFUSION IN PREVENTING PROLIFERATIVE VITREORETINOPATHY IN HIGH RISK PEDIATRIC RHEGMATOGENOUS RETINAL DETACHMENT
- Trial name
- NCT06166914
- Testing
- Intraoperative infusion of 5-FU (200 µg/ml) and LMWH (5 IU/ml)
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Alexandria University
Fetal Growth Retardation, Prematurity
LMWH for Treatment of Early Fetal Growth Restriction (HepaGrowth)
Early fetal growth restriction (FGR) is associated with considerable fetal and neonatal morbimortality. Placental thrombosis, infarcts and hypercoagulability are frequently seen in these pregnancies, suggesting a role for the…
- Conditions
- Fetal Growth Retardation, Prematurity, Pre-Eclampsia
- Trial name
- HepaGrowth (NCT04762992)
- Testing
- subcutaneous Enoxaparin, standard of care
- Where
- Portugal
- Volunteers
- 12 people
- Sponsor
- Centro Hospitalar de Lisboa Central
Unexplained Stillbirth
Low Molecular Weight Heparin in Pregnancies With Unexplained Stillbirths
Bemiparin for pregnant women with abnormal umbilical artery Doppler ultrasound
- Trial name
- NCT03601338
- Testing
- Bemiparin, multivitamins and routine antenatal follow up
- Where
- Iraq
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Brain Injury, Venous Thrombosis
The Use of Low Molecular Weight Heparin in Traumatic Brain Injury
To study the safety and efficacy of early administration of Low Molecular Weight Heparin to patients with traumatic brain injury.
- Trial name
- NCT00170378
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Hennepin Healthcare Research Institute
Deep Vein Thrombosis of Lower Limb, Pulmonary Embolism (PE)
Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH)
Evaluation of the safety and effectiveness of ActiveCare+ CECT device +/- baby dose aspirin (81 mg QD) for lowering the potential risk for bleeding and of DVT during and after THA surgery in comparison with LMWH.
- Conditions
- Deep Vein Thrombosis of Lower Limb, Pulmonary Embolism (PE), Bleeding
- Trial name
- SAFE (NCT00358735)
- Testing
- ActiveCare CECT device, Enoxaparin
- Where
- 9 sites in United States
- Volunteers
- 411 people
- Sponsor
- Medical Compression Systems
Venous Thromboembolism, Deep Vein Thrombosis
RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
Lower limb trauma requiring immobilization is a very frequent condition that is associated with an increased risk of developing venous thromboembolism (VTE).
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Lower Limb Trauma
- Trial name
- RIVACAST (NCT06195540)
- Testing
- Rivaroxaban 10 MG, Low Heparin Molecular Weight
- Where
- 37 sites in France
- Volunteers
- 1,424 people
- Sponsor
- University Hospital, Angers
Coagulation
Evaluation of the Accuracy of the INRatio Prothrombin Time (PT) Monitoring System With a New Test Strip for the Oral Anticoagulation Therapy Patient in the Presence of Heparin and Low Molecular Weight Heparin (e.g., Enoxaparin or Dalteparin)
This is a multi-center study designed to evaluate the heparin insensitivity of the INRatio Prothrombin Time (PT) Monitoring System, utilizing an INRatio test strip additionally modified for low sample volume.
- Trial name
- ECLIPSE 03 (NCT00933738)
- Where
- 12 sites in United States
- Volunteers
- 150 people
- Sponsor
- Abbott RDx Cardiometabolic
Deep Vein Thrombosis, Pulmonary Embolism
Thromboprophylaxis for Patients Undergoing Surgical Resection for Colon Cancer
The blood thinner "tinzaparin" might increase survival in patients with colon cancer undergoing surgical resection. The investigators want to assess if a trial allocating patients to prolonged treatment with tinzaparin versus…
- Conditions
- Deep Vein Thrombosis, Pulmonary Embolism, Cancer
- Trial name
- PERI-OP (NCT00967148)
- Testing
- Tinzaparin
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Ottawa Hospital Research Institute
Advanced Cancer, Metastatic Cancer
Prevention of Venous and Arterial Thromboembolism, in Cancer Patients Undergoing Chemotherapy, With a Low Molecular Weight Heparin (Nadroparin Calcium)
In this phase III, multicenter study, 1200 patients with lung, breast, gastrointestinal (stomach, colon-rectum, pancreas), ovarian or head and neck cancer undergoing chemotherapy will be randomly assigned (at the beginning of…
- Trial name
- NCT00951574
- Testing
- Nadroparin calcium
- Where
- 46 sites in Italy
- Volunteers
- 1,166 people
- Sponsor
- Italfarmaco
Venous Thromboembolism, Postpartum
PROSPER: PostpaRtum PrOphylaxiS for PE Randomized Control Trial Pilot
The purpose of this study is to determine if it is feasible to conduct a multi-center randomized trial to determine whether a blood thinner, low-molecular-weight-heparin (LMWH), is effective at preventing blood clots…
- Trial name
- PROSPER (NCT01274637)
- Testing
- Dalteparin Sodium
- Where
- 7 sites in United States, Canada
- Volunteers
- 62 people
- Sponsor
- Ottawa Hospital Research Institute
Critical Illness, Thrombosis
Influence of Vasopressors on Anti-Xa Activity in Critically Ill Patients
Critically ill patients require antithrombotic prophylaxis. At the same time, majority of them is receiving various vasopressors.
- Trial name
- NCT06055907
- Testing
- Serum anti-Xa activity
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Venous Thromboembolism, Lung Neoplasm
Prophylaxis of Venous Thromboembolism in Advanced Lung Cancer (PROVE)
Prospective randomized open multicenter trial with blinded adjudication of endpoints to assess the efficacy of six-month low-dose LMWH (Low Molecular Weight Heparin) for the prevention of symptomatic or incidental VTE in patients…
- Trial name
- PROVE (NCT03090880)
- Testing
- Tinzaparin Sodium
- Where
- 27 sites in France
- Volunteers
- 59 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deep Vein Thrombosis, Venous Thrombosis
A Randomized, Open-Label, Parallel-Group, Multi-Center Study for the Evaluation of Efficacy and Safety of Edoxaban Monotherapy Versus Low Molecular Weight (LMW) Heparin/Warfarin in Subjects With Symptomatic Deep-Vein Thrombosis
Assess the relative change in thrombus volume as determined by two assessments (Baseline and Day 14-21) with magnetic resonance venography (MRV) in subjects with deep-vein thrombosis (DVT) treated with either an edoxaban…
- Trial name
- eTRIS (NCT01662908)
- Testing
- edoxaban tosylate, enoxaparin/unfractionated heparin, warfarin
- Where
- 34 sites in United States, Canada
- Volunteers
- 85 people
- Sponsor
- Daiichi Sankyo
Kidney Failure, Acute
Safety and Efficacy of the Use of Regional Anticoagulation With Citrate in Continuous Venovenous Hemofiltration
Severely ill patients admitted to the intensive care unit may develop an acute failure of kidney function. To bridge the period to recovery, renal function is temporarily replaced by continuous venovenous hemofiltration (CVVH).
- Trial name
- NCT00286273
- Testing
- trisodium citrate, nadroparin
- Where
- Netherlands
- Volunteers
- 215 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Hip Fractures, Venous Thromboembolism (VTE)
Delivery and Implementation of a Randomised Crossover Trial on Thrombosis
What is the Study About? The DIRECT study (Delivery and Implementation of a Randomised Crossover Trial on Thrombosis) is a large research project investigating the best way to prevent blood clots (thrombosis) in people who break…
- Trial name
- DIRECT (NCT06937372)
- Testing
- Patients in hospitals allocated to this arm will receive aspirin as their routine thromboprophylaxis after surgery., Low molecular weight heparin (LMWH)
- Where
- United Kingdom
- Volunteers
- 21,194 people
- Sponsor
- Queen Mary University of London
Kidney Failure
A New Anticoagulation Method Using Dalteparin in Quotidian and Nocturnal Home Hemodialysis Patients
This study evaluates the optimal dosage and safety of Dalteparin when used as an anticoagulant for hemodialysis therapies.
- Trial name
- NCT02607111
- Testing
- Dalteparin
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Renal Insufficiency
Pharmacokinetics of Dalteparin in Patients With Impaired Renal Function
Low molecular weight heparins (LMWH) have been shown to be at least as efficient and safe as unfractioned heparin (UFH) in prophylaxis and treatment of venous thromboembolic events and in therapy of acute cardiovascular diseases.
- Trial name
- NCT00264693
- Where
- Switzerland
- Volunteers
- 96 people
- Sponsor
- Luzerner Kantonsspital
Stage I Multiple Myeloma, Stage II Multiple Myeloma
Dalteparin, Lenalidomide, and Low-Dose Dexamethasone in Treating Patients With Previously Untreated Multiple Myeloma
This randomized pilot phase II trial studies how well giving dalteparin, lenalidomide, and low-dose dexamethasone together works in treating patients with previously untreated multiple myeloma.
- Conditions
- Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma
- Trial name
- NCT01518465
- Testing
- dalteparin, lenalidomide, dexamethasone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Southern California
Lymphoma, Leukemia
Reduced-Dose Apixaban and Rivaroxaban Versus Low-Molecular-Weight Heparin in Patients With Hematologic Malignancies
This study investigates the efficacy and safety of direct oral anticoagulants (DOACs) in comparison with standard low-molecular-weight heparin (LMWH) for the prevention of venous thromboembolism in patients with hematological…
- Conditions
- Lymphoma, Leukemia, Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, Venous Thromboembolic Disease
- Trial name
- HEM-DOAC (NCT07270263)
- Testing
- Apixaban, Rivaroxaban, low molecular weight heparin (enoxaparin sodium)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Gdansk