Clinical trials: Damage Control, active
Athetoid CP, Cerebral Palsy (CP)
Comparison of Sensory Integration Therapy and Conventional Physical Therapy on Gross Motor Function in Children With Athetoid Cerebral Palsy: A Randomized Controlled Trial
This is an RCT aiming to explore the comparison of Sensory Integration Therapy and Conventional Physical Therapy on Gross Motor Function in Children with Athetoid Cerebral Palsy
- Trial name
- NCT07611565
- Testing
- Sensory Integration Therapy and Conventional Physical Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Ibadat International University, Islamabad
Primary Sjögren Syndrome
Study on Optimization and Evaluation of Integrated Chinese and Western Medicine for pSS Glandular Damage
ChatGPT In a randomized controlled trial, 136 patients with primary Sjögren's syndrome (pSS) meeting the inclusion criteria were enrolled and randomly divided into two groups of 68 each.
- Trial name
- NCT06519617
- Testing
- Yi Qi Yang Yin Decoction, Hydroxychloroquine Sulfate
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Qingwen Tao
Cerebral Palsy (CP)
Expiratory Muscle Training in Children With Cerebral Palsy
This study aims to examine the effects of expiratory muscle training on posture, trunk control, balance, selective motor control, and respiratory function in children with spastic-type cerebral palsy (CP).
- Trial name
- CP-EMT (NCT07048223)
- Testing
- Expiratory Muscle Training
- Volunteers
- 20 people
- Sponsor
- Istinye University
Cerebral Palsy, Hemiplegic
Effects of Robotic Hand Therapy on Hand Function and Dexterity in Cerebral Palsy
This randomized controlled trial aims to evaluate the effects of robotic hand therapy using the Syrebo E12 soft-robotic glove compared with conventional physiotherapy on hand function and manual dexterity in children with…
- Trial name
- NCT07571668
- Testing
- Robotic Hand Therapy, Conventional physical Therapy
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Riphah International University
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Skin Barrier Disruption and Recovery
Evaluation of a Peptide Cream on the Forearm Skin Recovery of Healthy Volunteers
The goal of this clinical trial is to evaluate the efficacy of a topical peptide-based formulation containing Acetyl Hexapeptide-37 in promoting skin barrier recovery after controlled disruption in healthy adult participants.
- Trial name
- NCT07614698
- Testing
- Acetyl Hexapeptide-37
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Minimally Conscious State
Neurological and Physiological Effects of Animal-assisted Therapy for Patients in a Minimally Conscious State
This study aims to explore the impact of Animal Assisted Therapy (AAT) on brain signal complexity in patients with minimally conscious state (MCS) by analyzing electroencephalogram (EEG) entropy.
- Trial name
- EMCS (NCT06931665)
- Testing
- Animal Assisted Occupational Therapy
- Where
- 2 sites in Switzerland
- Volunteers
- 26 people
- Sponsor
- University of Basel
Peripheral Neuropathy, Colorectal Cancer
Prevention of Oxaliplatin-induced Nerve Damage in the Body's Extremities
The purpose of this study is to examine the effect of supplementary polyunsaturated fatty acids on nerve damage in the body's extremitites of patients treated with oxaliplatin containing chemotherapy after surgery for colorectal…
- Trial name
- OxaNeuro (NCT05404230)
- Testing
- Fish oil, Corn oil
- Where
- 4 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Vejle Hospital
Celiac Disease
Study of DONQ52 in Active Celiac Disease
The main aim is to see how DONQ52 works to improve small intestinal damage and reduce celiac-related symptoms due to gluten exposure, in participants with celiac disease (CeD) attempting to maintain a gluten-free diet (GFD) in…
- Trial name
- NCT07239336
- Testing
- Simulated Inadvertent Gluten Exposure (SIGE) capsule, DONQ52
- Where
- 74 sites in United States, Australia and 1 more
- Volunteers
- 92 people
- Sponsor
- Chugai Pharmaceutical
Cerebral Palsy
Home-Based Training With Feedback to Improve Outcomes in Adolescents and Young Adults With Cerebral Palsy..
This clinical trial aims to determine whether extrinsic feedback through music enhances the effects of home-based motor training for adolescents and young adults with cerebral palsy (CP) and whether feedback improves adherence to…
- Trial name
- THRIVE-CP (NCT06962618)
- Testing
- Music Motion Group, Control
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- University of Copenhagen
Abdominal Trauma, Damage Control Surgery
Clinical Outcomes of Non-Indicated Staged Laparotomies in Abdominal Trauma
The goal of this observational study is to understand how often staged operations are performed in abdominal trauma patients without meeting standard clinical criteria, and to explore related clinical characteristics and…
- Conditions
- Abdominal Trauma, Damage Control Surgery, Laparotomy
- Trial name
- NCT07110350
- Testing
- Laparotomy refers to a definitive single-stage exploratory abdominal surgery. Damage Control Surgery refers to a staged surgical approach including initial abbreviated laparotomy followed by planned.
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- Far Eastern Memorial Hospital
Cerebral Palsy
Intensive Somatosensory Camp for Manual Function and Participation in Children With Unilateral Cerebral Palsy
This study will evaluate whether an intensive day camp that combines somatosensory and motor training for the affected upper limb improves hand function and participation in children with unilateral cerebral palsy more than an…
- Trial name
- CAMPUSENS (NCT07487857)
- Testing
- Somatosensory-Motor Intensive Camp, Motor-Only Intensive Camp
- Volunteers
- 26 people
- Sponsor
- University of Castilla-La Mancha
Cerebral Palsy
The Effects of Inspiratory Muscle Training in Children With Cerebral Palsy
Cerebral palsy (CP) is characterized by permanent or variable sensory-motor function impairments resulting from developmental anomalies or damage to the brain.
- Trial name
- NCT06640686
- Testing
- Exercise training
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Spastic Diplegic Cerebral Palsy
Effects of Transcranial Direct Current Stimulation Combined With Virtual Reality on Gait and Self-Esteem in Children With Spastic Cerebral Palsy
Cerebral palsy can affect walking ability, muscle control, functional mobility, and psychosocial well-being in children. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that may…
- Trial name
- NCT07829796
- Testing
- Active Transcranial Direct Current Stimulation, Virtual Reality Rehabilitation, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Cerebral Palsy, Cerebral Palsy (CP)
Individualized Nutrition Intervention in Children With Cerebral Palsy
The goal of this clinical trial is to learn if individualized nutrition support can improve nutrition, gastrointestinal symptoms, and quality of life in children with cerebral palsy.
- Trial name
- CP-NUTRI (NCT07644572)
- Testing
- Individualized Nutrition Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Gazi University
Cerebral Palsy, Spasticity, Muscle
Investıgatıon Of The Effectıveness Of The Mollıı Suıt In Chıldren Wıth Ambulatory Cerebral Palsy
Cerebral Palsy (CP) is the most common developmental disorder in childhood. Individuals' independence in daily living activities and participation in education, games, social and community activities are restricted.
- Trial name
- NCT06109129
- Testing
- EXOPULSE Mollii Suit
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Kastamonu University
Cerebral Palsy, Spastic
Power2Walk: The Impact of Functional Power Training on Participation and Activity in Children With Cerebral Palsy.
Rationale: Children with cerebral palsy (CP) experience limitations in walking ability due to functional motor impairments caused by neurodevelopmental damage during fetal or early child development.
- Trial name
- Power2Walk (NCT06640894)
- Testing
- MegaPower training, Usual Care
- Where
- 10 sites in Netherlands
- Volunteers
- 66 people
- Sponsor
- Amsterdam UMC, location VUmc
Corneal Endothelial Cell Loss, Corneal Endothelial Damage Following the Hard Nuclear Cataract Surgery
A Study of CA201A Eye Drops to Prevent Corneal Endothelial Cell Loss in Patients Undergoing Cataract Surgery
This study is designed to assess whether an investigational eye drop called CA201A can help protect the cornea (the outer covering of the eye) and reduce damage to corneal endothelial cells following cataract surgery, without…
- Trial name
- NCT07694375
- Testing
- Ophthalmic solution (matching formulation without ascorbic acid), Ascorbic acid ophthalmic solution 5%
- Where
- 8 sites in Australia
- Volunteers
- 200 people
- Sponsor
- Caravel Oculus Pty Ltd
Stroke, TBI
Assessment of Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments
This study will evaluate the safety and performance of the Spatial StimeMD (SSMD) medical device in people with multiple sclerosis (MS). The SSMD device is intended to support patients through a non-invasive stimulation program.
- Conditions
- Stroke, TBI, Spinal Cord Injury, Peripheral Nerve Damage
- Trial name
- NCT07396922
- Testing
- SSMD, Functional Electrical Stimulation (FES)
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Motion Informatics LTD
Skin Melanoma, Cutaneous Melanoma
Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria
The goal of this observational study is to learn about the link between work-related sun exposure and a specific type of skin cancer called melanoma in people living in the Modena area, Italy.
- Trial name
- Mesur (NCT07251335)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Modena and Reggio Emilia