Clinical trials: Damage Muscle
Cerebral Palsy, Muscle Contracture
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contracture, Spasticity, Muscle
- Trial name
- CPMuscleSL (NCT05518565)
- Testing
- No intervention
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Eva Ponten
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Reconstruction of the Anterior Cruciate Ligament of the Knee Joint, by the Method of Stabilization of the Screw With a Bioabsorbable Method, With or Without the Use of Autogenous Spongiform Bone Grafts.
Clinical and comparative evaluation of the results of autograft healing of the tendon of the semitendinus muscle in the tibial canal, after reconstruction of the anterior cruciate ligament of the knee joint, by the method of…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Knee Injuries
- Trial name
- NCT05328544
- Testing
- ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) with the use of autogenous cancellous bone grafts, ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) without the use of autogenous cancellous bone grafts
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- eMKa MED Medical Center
Cerebral Palsy, Spastic
Stretching in Children and Adolescents With Spastic Cerebral Palsy
The primary aim of this study is to gain knowledge about both the effects of a single bout of static and proprioceptive neuromuscular facilitation (PNF) stretching and the effects of 8-week static and PNF stretching training on…
- Trial name
- NCT04570358
- Testing
- Static stretching, Proprioceptive neuromuscular facilitation stretching
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- University of Graz
Anaerobic Performance, Sports Nutrition
Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females
This study is a randomized, double-blind, placebo-controlled trial designed to examine the effects of pre-sleep creatine monohydrate supplementation on anaerobic performance and muscle damage markers in recreationally active…
- Conditions
- Anaerobic Performance, Sports Nutrition, Exercise Recovery, Muscle Fatigue
- Trial name
- SleepCrM (NCT06937190)
- Testing
- Creatine Monohydrate
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Nutrition, Healthy, Muscle Damage
Early Time-Restricted Eating in Young Judo Athletes
This study investigates the effects of a 5-month early time-restricted eating (e-TRE) intervention on body composition, muscle damage biomarkers, and psychological variables in highly trained young male judo athletes.
- Conditions
- Nutrition, Healthy, Muscle Damage, Time Restricted Eating, Anxiety
- Trial name
- TRE-JUDO (NCT07671443)
- Testing
- Early Time-Restricted Eating (e-TRE)
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Manouba
Recurrent Crying Spells
Recurrent Crying Spells in Cerebral Palsy
This is a study of recurrent crying spells in Spastic Cerebral Palsy patients and their treatment.
- Trial name
- RCSCPSQ (NCT01955655)
- Testing
- Baclofen
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Sathbhavana Brain Clinic
Performance
Effect of Blueberry Supplementation on Liver Enzymes, Muscle Injury and Respiratory Parameter in Football Athletes: A Eight-Week Training Study
Abstract Background and objective: Regular Exercise causes physiological changes in the body. As a result, its impact on liver enzymes and muscle injury is unknown.
- Trial name
- NCT07170878
- Testing
- Blueberry Supplementation, Supplementation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Spasticity, Muscle, Cerebral Palsy
Effect of Number of Pulses of Radial Extracorporeal Shock Wave Therapy on Hamstring Spasticity in Children With Cerebral Palsy
Cerebral palsy (CP) is a group of permanent disorders affecting movement and postural development that are caused by non-progressive disruptions of the brain, usually occurring during fetal period or infancy.
- Conditions
- Spasticity, Muscle, Cerebral Palsy, Child; Spastic
- Trial name
- NCT04546035
- Testing
- radial Extracorporeal Shockwave Therapy
- Where
- Indonesia
- Volunteers
- 13 people
- Sponsor
- Rizky Kusuma Wardhani
Cerebral Palsy (CP), Spasticity
Effects Of Dry Needling On Mobility Among Children With Cerebral Palsy
This study explores the potential of dry needling as a treatment for spasticity in the foot among children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Spasticity, Range of Motion, Functional Mobility
- Trial name
- DRYSPARC (NCT06661421)
- Testing
- Dry Needling, Cerebral Palsy conventional Treatment
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Sports Performance, Injury Prevention
Effect of Whole-body Photobiomodulation on Muscular Performance Enhancement.
Introduction: Photobiomodulation therapy (PBMT) is based on the emission of light ranging from red to near-infrared spectra by different devices based on diode lasers or light-emitting diodes.
- Conditions
- Sports Performance, Injury Prevention, Muscle Damage, Musculoskeletal Pain
- Trial name
- WBPME (NCT05989815)
- Testing
- Muscle damage protocol training, Photobiomodulation therapy (PBMT)
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
MELAS Syndrome
Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome
The purpose of this study is to assesses the efficacy of oral supplementation with glutamine over three months on several amino acids and lactate concentration measured in cerebrospinal fluid and cerebral lactate measured by…
- Trial name
- NCT04948138
- Testing
- Glutamine oral supplementation
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- Jesús González de la Aleja Tejera
Pain, Cerebral Palsy, Spastic
Botulinum Toxin-A as a Treatment for Chronic Muscle-Related Pain in Adults With Spastic Cerebral Palsy: a Randomized Controlled Trial
The purpose of this double-blinded, placebo-controlled study is to test if treatment with Botulinum toxin-A is effective in reducing chronic muscle-related pain in adults with spastic cerebral palsy.
- Trial name
- BATCP (NCT02434549)
- Testing
- Dysport®, Normal saline
- Where
- 2 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Kristina Tedroff
Erectile Dysfunction Due to Diseases Classified Elsewhere, Covid19
Effects of COVID-19 on Cavernous Smooth Muscle
The aim of the study is to illuminate the role of COVID-19 in the pathophysiology of erectile dysfunction (ED). Nine patients that had COVID-19 and were treated as outpatients were classified as group 1, 10 patients who were…
- Trial name
- NCT04980508
- Testing
- corpus cavernosum electromyography
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cerebral Palsy (CP)
Whole Body Metabolism in Children With Cerebral Palsy With Low Skeletal Muscle Mass
At the center of pediatrics in Copenhagen the investigators experience that the children with CP with low skeletal muscle mass have more complications and admission after for example surgery is prolonged due to these…
- Trial name
- NCT06486597
- Testing
- Meal
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cerebral Palsy (CP)
Fascial Manipulation in Cerebral Palsy Rehabilitation
The purpose of the study is to investigate the potential additional benefits of a relatively new physiotherapy method, fascial manipulation, in the rehabilitation of movement difficulties or other problems caused by CP (cerebral…
- Trial name
- CP fascia (NCT06837025)
- Testing
- Fascial manipulation
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Orton Orthopaedic Hospital
Immune Markers, Complete Blood Count (CBC) With Platelet Differentials
Immune and Recovery Modulating Impact of Probiotic Supplementation After Intense Resistance Exercise
This study proposal seeks to examine the efficacy of probiotic supplementation at mitigating changes in immune function and recovery after completion of intense, stressful exercise while also allowing for a better understanding…
- Conditions
- Immune Markers, Complete Blood Count (CBC) With Platelet Differentials, Muscle Damage, Muscular Force Production
- Trial name
- NCT04441840
- Testing
- Active Probiotic Culture, Inactive Probiotic Culture
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Healhty
Grape Seed Extract Supplementation on Cycling Time-to-Exhaustion Performance.
To address the physical fatigue and muscle recovery demands in endurance exercise, this study evaluates Grape Seed Extract (GSE) as a potential ergogenic aid.
- Trial name
- NCT07867977
- Testing
- Grape seed extract
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Cerebral Palsy
Robotic Exoskeleton Gait Training for Children With Cerebral Palsy
The goal of this clinical trial is to evaluate whether robotic-assisted gait training can improve motor function, walking capacity, joint flexibility, muscle structure, and psychological well-being in children aged 6 to 12 years…
- Trial name
- NCT07049523
- Testing
- Robotic-assisted gait training
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Hunan Normal University
Muscle Damage, Athletic Performance
The Combined Effects of Cordyceps and Fartlek Training on Muscle Recovery and Bone Health in Soccer Players
Purpose of the Study:This study aims to evaluate the effectiveness of combining Cordyceps supplementation and fartlek training as a recovery and performance enhancement strategy for soccer players.
- Conditions
- Muscle Damage, Athletic Performance, Oxidative Stress, Inflammation
- Trial name
- COR-FAST (NCT07726979)
- Testing
- Fartlek Training Program, Cordyceps sinensis Supplementation
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Cerebral Palsy, Muscle Spasticity
Dysport® Pediatric Lower Limb Spasticity Study
The purpose of this research study is to determine whether Dysport® is effective in the treatment of increased stiffness of the calf muscles and to evaluate the safety of this treatment in children with Cerebral Palsy.
- Conditions
- Cerebral Palsy, Muscle Spasticity, Children
- Trial name
- NCT01249417
- Testing
- Botulinum toxin type A
- Where
- 29 sites in United States, Chile and 4 more
- Volunteers
- 241 people
- Sponsor
- Ipsen