Clinical trials: Data Quality
Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis
2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness and Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis
This was an observational, prospective primary data collection study. The duration of observation was 2 years after study enrolment date.
- Conditions
- Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis
- Trial name
- PROMPT (NCT05155098)
- Testing
- secukinumab
- Where
- 10 sites in Thailand
- Volunteers
- 127 people
- Sponsor
- Novartis Pharmaceuticals
Telomere Length, Mean Leukocyte, Diet Habit
Diet Quality and LTL in NHANES
In our study, we used data from 4,758 healthy adults from the 1999-2002 National Health and Nutrition Examination Surveys to examine the associations between evidence-based diet quality indices and leukocyte telomere length.
- Trial name
- NCT03302104
- Volunteers
- 4,758 people
- Sponsor
- University of California, San Francisco
Parenteral Nutrition, Home
Evaluation of a Connected Parenteral Pump for Patients Treated by Home Parenteral Nutrition (HPN).
Patients requiring long-term home parenteral nutrition (HPN) suffer from chronic intestinal insufficiency. The causes of this syndrome can be either anatomical (extensive resection of the small bowel) or functional (occlusion…
- Trial name
- SERENE-eNUTRI (NCT04406766)
- Testing
- Connected nutrition pump system
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Grenoble
MDS (Myelodysplastic Syndrome), AML (Acute Myeloid Leukemia)
WearAble Technology for Collecting Health Data in People Who Are the Transfused (WATCH Transfused) - A UK Exploratory Study to Improve Quality of Life and the Efficacy of Transfusion Supportive Care in People With Blood Cancers Undergoing Treatment
Cancer treatments such as chemotherapy often affect healthy cells as well as the cancer cells and this can lead to side-effects such as low blood counts - anaemia.
- Trial name
- WATCH Tranfuse (NCT07511829)
- Testing
- Axvitiy Ax3 accelorometer
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Oxford
Prostate Cancer, Prostate Cancer Metastatic
An AI Platform Integrating Imaging Data and Models, Supporting Precision Care Through Prostate Cancer's Continuum
In Europe, prostate cancer (PCa) is the second most frequent type of cancer in men and the fifth most lethal. Current clinical practices, often leading to overdiagnosis and overtreatment of indolent tumors, suffer from lack of…
- Conditions
- Prostate Cancer, Prostate Cancer Metastatic, Prostate Cancer Recurrent, Prostate Cancer Aggressiveness
- Trial name
- NCT05384002
- Testing
- Magnetic Resonance Imaging
- Where
- Italy
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Immune Thrombocytopenia
Evaluation of HRQoL in Adult With Immune Thrombocytopenia in China
Immune thrombocytopenia (ITP) is a heterogeneous disorder with variable clinical symptomsHealth related quality of life (HRQoL) could be considered in ITP, as in numerous chronic diseases, as a method to provide information about…
- Trial name
- HRQoL (NCT03324087)
- Testing
- HRQoL
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shandong University
Compare Image Quality Between SDCT and Conventional CT Images of Any Tissue Lesion, Determine Optimal Monochromatic Energy Level for a Coronary Artery Image
Preliminary Assessment of Added Diagnostic Value of Dual Energy CT Images Using Data Acquired on a Spectral Detector CT
Study hypothesis: Post-processed SDCT images provide additional diagnostic value over conventional CT datasets. The CT examination would be a clinically-necessary, standard-of-care CT performed as per the clinical indication.
- Trial name
- NCT02760706
- Testing
- Computed Tomography scan
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Philips Healthcare
Holistic Care, Mental Health
Using Integrated Care and Wearable Technology to Evaluate Outcomes of the Shields & Stripes Program for Veterans and First Responders
This study aims to evaluate outcomes from the Shields \& Stripes (S\&S) program - a 12-week, multidisciplinary wellness intervention designed for veterans and first responders.
- Conditions
- Holistic Care, Mental Health, Sleep, PTSD
- Trial name
- S&S Wellness (NCT07452900)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor University
Lung Cancer, Quality of Life
Improvement of Quality of Life (QoL) Using Preference-Oriented QoLMonitoring in Patients with Lung Cancer
The purpose of the study is to determine whether a preference-oriented quality of life monitoring with defined diagnostic and therapeutic options improves quality of life in patients with lung cancer during routine follow-up care.
- Trial name
- LePaLuMo (NCT06252233)
- Testing
- patient- and physician-centered QoL monitoring
- Where
- 8 sites in Germany
- Volunteers
- 220 people
- Sponsor
- University of Bayreuth
Quality of Life, Epilepsy (treatment Refractory)
Evaluation of the Epilepsy-related Quality of Life, Seizure-related Accidents and Validation of the Mjn-SERAS Solution in the Normalised Patient Environment with Real-World Data
The study will be prospective, multicentre, postmarketing clinical study, with a controlled and randomized design, to perform the analysis of 130 subjects with a clinical diagnosis of epilepsy, patients whose clinical semiology…
- Trial name
- SERAS_Home_RWD (NCT05845255)
- Testing
- mjn-SERAS
- Where
- 6 sites in Germany, Spain and 1 more
- Volunteers
- 130 people
- Sponsor
- MJN Neuroserveis, S.L
Cancer
Evaluating the Use of Patient-Reported Outcome Measures for Improving the Inter-Rater Reliability of Common Terminology Criteria for Adverse Event Ratings
This open randomized trial investigates, if clinicians complete CTCAE ratings differently when receiving patients' patient-reported outcome (PRO) data prior to their CTCAE completion.
- Trial name
- NCT04066868
- Testing
- Patient-reported outcomes assessment, CTCAE rating, PRO data is displayed
- Where
- Austria
- Volunteers
- 1,013 people
- Sponsor
- Medical University Innsbruck
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.
Aging, SARS-CoV-2 Infection
Impact of the COVID-19 Pandemic on the Health Status of People Aged 75 and Over and Their Caregivers
The measures to control the transmissibility of the Covid-19 pandemic have changed the daily routines of the population, increasing sedentary lifestyles, decreasing outdoor physical activity and limiting contact with neighbors…
- Conditions
- Aging, SARS-CoV-2 Infection, Caregivers, Frailty
- Trial name
- CUIDAMOS+75 (NCT05249868)
- Testing
- Exposure SARS-CoV-2 Infection
- Where
- 2 sites in Spain
- Volunteers
- 1,035 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Postoperative Complications, Complications of Surgical Procedures or Medical Care
Effects of Checklists in Surgical Care - a Study on Complications, Death and Quality of Patient Administrative Data
This project aims to produce a systematic review on present knowledge on effects of using safety checklists in medicine. Implementation of a checklist system throughout surgical care may reduce patient morbidity and mortality.
- Trial name
- NCT01872195
- Testing
- The comprehensive patient safety checklist system
- Where
- Norway
- Volunteers
- 21,000 people
- Sponsor
- Haukeland University Hospital
Diabetes Mellitus, Type 1
Children's Hospital Academic Medical Organization (CHAMO) MyChart Study
Evolving technology and clinical innovation have led to dramatic changes in the management of type 1 diabetes (T1D). These changes have led to a need to collect a growing number of details from families during their visits.
- Trial name
- NCT05979077
- Testing
- MyChart Questionnaire
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Eastern Ontario
Training, Quality of Care
Training and Support Programme on Data-driven Quality Development for Swiss Long-Term Care Facilities (NIP-Q-UPGRADE Subaim 2.6)
Since 2019, long-term care facilities (LTCFs) in Switzerland have been required by the Federal Insurance Law (KVG, Art. 59a) to report data for the calculation and public reporting of medical quality indicators (MQIs) in four…
- Conditions
- Training, Quality of Care, Quality Indicators, Health Care, Long Term Care
- Trial name
- NCT07068009
- Testing
- Training and Support Programme on Data-driven Quality Development
- Where
- 3 sites in Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Institut et Haute Ecole de la Santé la Source
Hemophilia A
Health-Related Quality of Life Outcomes and Bleeding Rates Among Patients With Severe Hemophilia A on Emicizumab
The main purposes of this study are to determine if use of emicizumab prophylaxis treatment reduces number of bleeding episodes, if it improves quality of life of individuals and if improves arthropathy in persons with hemophilia…
- Trial name
- ML43518 (NCT06104826)
- Testing
- Emicizumab
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Newark Beth Israel Medical Center
Crohn Disease, Colitis, Ulcerative
A Study to Evaluate Disease Control, Treatment Patterns, Burden of Disease and Quality of Life in Participants With Moderate to Severe Inflammatory Bowel Disease (IBD)
The purpose of this study is to evaluate the percentage of moderate to severe IBD participants with active disease at Day 1.
- Conditions
- Crohn Disease, Colitis, Ulcerative, Inflammatory Bowel Disease
- Trial name
- RISE AR (NCT03488030)
- Where
- 7 sites in Argentina
- Volunteers
- 246 people
- Sponsor
- Takeda
Cancer, Symptom
Advanced Symptom Palliation Through Integrated Relief Engagement
Beacon is a digital platform that processes objective and subjective aggregated data provided by patients. Objective data is provided by standard wearables, while subjective data is provided by patient-reported outcome measures…
- Conditions
- Cancer, Symptom, Quality of Life, AI (Artificial Intelligence)
- Trial name
- ASPIRE AI (NCT07518797)
- Testing
- Advanced cancer patients' palliative symptoms management using Beacon analysis of patient-provided of objective and subjective data
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Tzeela Cohen
Osteoporotic Fractures
Impact of Osteoporotic Fractures on Work: Data From a Fracture Liaisons Service
Osteoporosis is a bone disease characterized by a decrease in bone density with deterioration of the micro-architecture and the appearance of bone fragility, responsible for an increased risk of fractures.
- Trial name
- OPTIWORK (NCT04781556)
- Testing
- No intervention
- Where
- France
- Volunteers
- 121 people
- Sponsor
- Fondation Hôpital Saint-Joseph