Clinical trials: Database, open to volunteers
Breast Cancer
Clinical Database of Safe Personalized Adjuvant Breast Radiotherapy Based on Individual Radiosensitivity
Severe but also moderate toxicities after curative-intent radiotherapy (RT), such as a poor cosmetic outcome following breast cancer can have a negative impact on quality of life and a marked effect on subsequent psychological…
- Trial name
- SAHARA-01 (NCT04282122)
- Testing
- Radiotherapy
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting
REAL-MS: Observational Database Study of AHSCT and MS Therapies
Multiple sclerosis (MS) is a condition in which the immune system damages the brain and spinal cord. Treatments called disease-modifying therapies can reduce inflammation and disease activity.
- Conditions
- Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive
- Trial name
- REAL-MS (NCT07899502)
- Testing
- Autologous haematopoietic stem cell transplantation (AHSCT), High-efficacy disease-modifying therapy (HE-DMT)
- Where
- 3 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Imperial College London
Orthopedic Disorder
A Clinical Registry of Orthobiologics Procedures
The purpose of the Registry study is to observe the improvement in subject-reported clinical outcomes for percutaneous orthopedic procedures for treatment of musculoskeletal disorders.
- Trial name
- NCT03011398
- Testing
- Orthobiologic Procedures
- Where
- 32 sites in United States, Australia and 1 more
- Volunteers
- 50,000 people
- Sponsor
- Regenexx, LLC
Healthy Related
Azoospermia Patients
The Prospective Cohort Study for Azoospermia Patients was set up to investigate the short- and long-term health consequences in Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University, China.
- Trial name
- NCT03991663
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Liver Diseases, Humans
Liver Disease and Other Systemic Diseases
Examine the association of chronic liver diseases (including hepatitis B, hepatitis C, alcoholic liver disease, fatty liver, liver cirrhosis, and hepatocellular carcinoma) with other systemic diseases by retrospectively analyzing…
- Conditions
- Liver Diseases, Humans, Progression, Carcinogenesis
- Trial name
- NCT04525833
- Where
- Taiwan
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Cancer of the Ovary, Cancer of the Fallopian Tube
Prospective Clinico-biological Database of Patients With Ovarian and/or Peritoneal and/or Fallopian Tube Carcinoma
Cancer of the ovary and/or peritoneum and/or fallopian tube have a very poor prognosis, and require the implementation of collaborative research tools and new innovative therapies.
- Conditions
- Cancer of the Ovary, Cancer of the Fallopian Tube, Peritoneal Cancer
- Trial name
- BCB-OVAIRE (NCT06969833)
- Testing
- Constitution of a biological collection, Assessment of Quality of Life and level of anxiety/depression
- Where
- France
- Volunteers
- 371 people
- Sponsor
- Centre Oscar Lambret
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Digestive System Neoplasm
A Clinicobiological Database in Metastatic Digestive Cancers
Creation of a collection of blood samples that will be collected before and then under treatment in patients with digestive adenocarcinoma during the 1st and 2nd metastatic line and which, depending on scientific progress, can be…
- Trial name
- BCB-CBIO-DIG (NCT03978078)
- Testing
- Biological collection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Obesity, Metabolic Abnormalities
Obesity Medicine Bank of the Quebec Heart and Lung Institute - Laval University (IUCPQ-ULaval)
Obesity medicine, or bariatric medicine, focuses not only on the biological and behavioral aspects, but also on the environmental and social factors that contribute to the development of obesity.
- Conditions
- Obesity, Metabolic Abnormalities, Health
- Trial name
- NCT07472608
- Testing
- Behavioral and Pharmacological Treatments
- Where
- Canada
- Volunteers
- 25,000 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Hyperthermia, Cancer
Prospective Hyperthermia Database in Cancer Patients (HT Register)
This monocentric study registry records all cancer patients at the Charité which are treated with hyperthermia to examine the therapeutic use of hyperthermia in cancer patients in the general application and to obtain an accurate…
- Trial name
- HTRegister (NCT05993910)
- Testing
- Hyperthermie Register
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- Pirus Ghadjar
Lung Cancer
Clinico-biological Data Collection Study of Metastatic Lung Cancer
RATIONALE : Currently, the mechanisms associated with the response or resistance to treatment are poorly understood and are multifactorial.
- Trial name
- EPICURE_LUNG (NCT04944030)
- Testing
- Metastasis biopsy
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Institut Cancerologie de l'Ouest
Healthy Eyes
Clinical Investigation of MAIA Microperimeter Device: Mesopic Normative Database Collection
The purpose of this pre-market, multicentric cross-sectional study is to create a mesopic Normative Database for a new version of the MAIA device. Moreover, the study aims to evaluate MAIA safety and adverse events.
- Trial name
- NCT06991127
- Testing
- MAIA
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Centervue SpA
Endocrine Disease
Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal Disease
The goal of this data review study is to collect data to learn more about thyroid, parathyroid, and adrenal disease.
- Trial name
- NCT03050762
- Testing
- Data Collection, Follow Up
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- M.D. Anderson Cancer Center
Myelodysplastic Syndromes
Institut Paoli Calmettes Myelodysplastic Syndromes Database
Database of Institut Paoli-Calmettes patients diagnosed with Myelodysplastic Syndromes
- Trial name
- NCT03275480
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- Institut Paoli-Calmettes
Drowning, Drowning, Near
Developing an Utstein-style Danish Drowning Registry: Nationwide Fatal and Nonfatal Drowning Data Since 2016
This nationwide, registry-based study aims to link Danish Prehospital Drowning Data data with inhospital data to develop a Utstein-style Danish Drowning Registry.
- Conditions
- Drowning, Drowning, Near, Drowning; Asphyxia, Drowning and Nonfatal Submersion
- Trial name
- DROWN_INHOS (NCT06334276)
- Testing
- Drowning
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Prehospital Center, Region Zealand
Healthy
Multi-omics Database Construction of Healthy Korean Volunteers
The goal of this prospective, observational study is to collect health-related data including microbiome, blood samples, and dietary habits from the oral and gastrointestinal tracts in healthy subjects.
- Trial name
- NCT06183697
- Where
- South Korea
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Kyunghee University Medical Center
Gastroparesis
Gastroparesis Outcome Longitudinal Database Enrolled Numerically
GOLDEN is a longitudinal database of patients with the symptoms (Sx) of gastroparesis (Gp) who were seen and recorded at the University of Louisville from 2012 and is ongoing.
- Trial name
- GOLDEN (NCT03876288)
- Testing
- GI Neuromodulation, Immunotherapy, Pyloric Therapies
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of Louisville
Quality of Care, Evaluation
Evaluation of the Quality of Care in the Emergency Department by Studying the Appropriateness of Hospitalizations
The aim of this study is to develop, study and validate a rigorous and sustainable method for assessing the clinical appropriateness of the decision taken in the Emergency Department to admit or not to admit patients.
- Conditions
- Quality of Care, Evaluation, Emergency Department, Appropriateness
- Trial name
- NCT06846879
- Where
- 7 sites in Italy
- Volunteers
- 240,000 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Gastric Cancer, Colorectal Cancer
Development and Utilization of an Integrated Clinical Genomic Database
This observational study aims to develop an integrated genomic and clinical database to support the discovery and validation of biomarkers for cancer diagnosis, treatment selection, and prediction of treatment response.
- Conditions
- Gastric Cancer, Colorectal Cancer, Lung Cancer (NSCLC), Liver Cancer
- Trial name
- SMC-4S (NCT07911267)
- Where
- South Korea
- Volunteers
- 118,750 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Liver Cancer (Primary and Metastatic)
Prospective Clinical Database Construction for Liver Cancer Diagnosis and Treatment
This study is a prospective, observational, real-world cohort study. We aim to establish a prospective database in the Department of Hepatobiliary and Pancreatic Surgery, systematically collecting and integrating patients'…
- Trial name
- NCT07587216
- Testing
- liver resection, Systemic therapy combined with locoregional interventions
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Tongji Hospital