Clinical trials: Database, open to volunteers
Upper Gastrointestinal Cancer, Upper Gastrointestinal Precancerous Lesions
Establishment of Image Database for Early Upper Gastrointestinal Cancer, Precancerous Lesions, and Precancerous Conditions
The study is designed to collect magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, CT images, and histopathology results to establish a database for early upper gastrointestinal…
- Conditions
- Upper Gastrointestinal Cancer, Upper Gastrointestinal Precancerous Lesions, Upper Gastrointestinal Precancerous Conditions
- Trial name
- NCT07462247
- Testing
- magnetically-controlled capsule endoscopy, esophagogastroduodenoscopy, CT scan, ESD, biopsy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Changhai Hospital
Lung Cancer, Bronchial Cancer
Development of Clinical and Biological Database on Bronchial Cancer
A Clinical and Biological Database will provide to the scientific community a collection of blood and tissues with clinical data to improve knowledge about cancer and help to develope new cancer treatments.
- Trial name
- BCBPoumon (NCT07085429)
- Testing
- Blood and tissue sampling
- Where
- France
- Volunteers
- 750 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Esophageal Disease
The French EsoGastricTumours Data Base
This retrospective study aims at evaluating the outcomes of gastrointestinal stromal tumor after surgery.
- Trial name
- FREGAT (NCT02526095)
- Where
- 31 sites in France
- Volunteers
- 15,000 people
- Sponsor
- University Hospital, Lille
Rehabilitation
Rehablines: a Further Use Databank to (re)Use Routine Clinical Data for Scientific Research in Rehabilitation of People With Physical Disabilities and/or Chronic Diseases
Within the Center of Rehabilitation multidisciplinary treatment is provided to people with various physical disabilities and/or chronic diseases. During and in the context of this treatment, a lot of data is routinely collected.
- Trial name
- Rehablines (NCT06750601)
- Where
- Netherlands
- Volunteers
- 20,000 people
- Sponsor
- University Medical Center Groningen
Malignant Melanoma
Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable Primary
Prevention of melanoma can be efficient but mortality remains unchanged and 15 to 20% of patients still die from melanoma. Indeed metastatic melanoma is a heterogeneous highly and multiple mutations driven cancer.
- Trial name
- MelBase (NCT02828202)
- Testing
- Biological, Tissular, Quality of life
- Where
- 27 sites in France
- Volunteers
- 6,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Metabolic Surgery
Beijing Friendship Hospital Metabolic Surgery Database
Metabolic surgery, as a recognition treatment option for patients with clinical morbid obesity, is gaining increasing appreciation.
- Trial name
- NCT03520699
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Friendship Hospital
Obesity, Metabolic Abnormalities
Obesity Medicine Bank of the Quebec Heart and Lung Institute - Laval University (IUCPQ-ULaval)
Obesity medicine, or bariatric medicine, focuses not only on the biological and behavioral aspects, but also on the environmental and social factors that contribute to the development of obesity.
- Conditions
- Obesity, Metabolic Abnormalities, Health
- Trial name
- NCT07472608
- Testing
- Behavioral and Pharmacological Treatments
- Where
- Canada
- Volunteers
- 25,000 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension
DataBase of pulmoNary hyPertesion in PoLish Population - BNP-PL
The BNP-PL is a multicenter, observational study in which patients are prospectively followed in order to investigate clinical course and management of pulmonary hypertension in Poland.
- Trial name
- BNP-PL (NCT03959748)
- Where
- Poland
- Volunteers
- 3,000 people
- Sponsor
- Polish Cardiology Association
Chronic Disease, HIV/AIDS
Observational Pharmaco-Epidemiology Research & Analysis
Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of routine patient care, population management and disease management…
- Conditions
- Chronic Disease, HIV/AIDS, Liver Diseases, Inflammatory Bowel Diseases
- Trial name
- OPERA (NCT03813862)
- Testing
- Non-interventional (observational only)
- Where
- United States
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- Epividian
Gastroparesis
Gastroparesis Outcome Longitudinal Database Enrolled Numerically
GOLDEN is a longitudinal database of patients with the symptoms (Sx) of gastroparesis (Gp) who were seen and recorded at the University of Louisville from 2012 and is ongoing.
- Trial name
- GOLDEN (NCT03876288)
- Testing
- GI Neuromodulation, Immunotherapy, Pyloric Therapies
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of Louisville
Ephedrine, Norepinephrine
Postoperative Delirium After Intraoperative Ephedrine Versus Norepinephrine
This retrospective study aims to investigate the effects of norepinephrine compared to ephedrine, administered on the day of surgery, on the incidence of postoperative delirium.
- Conditions
- Ephedrine, Norepinephrine, Postoperative Delirium (POD)
- Trial name
- NCT06844201
- Testing
- Ephedrine, Norepinephrine
- Volunteers
- 10,000 people
- Sponsor
- Riverside University Health System Medical Center
Primary Sclerosing Cholangitis
National Database on Primary Sclerosing Cholangitis (PSC)
Primary sclerosing cholangitis (PSC) a rare, chronic fibroinflammatory disease of the liver. No data about the disease epidemiology exist in Italy.
- Trial name
- NCT05618145
- Testing
- Clinical information
- Where
- 63 sites in Italy
- Volunteers
- 6,000 people
- Sponsor
- University of Milano Bicocca
Retinoblastoma, Retinoblastoma Bilateral
Retinoblastoma Patient Clinical Database and Tissue Repository
Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed.
- Conditions
- Retinoblastoma, Retinoblastoma Bilateral, Retinoblastoma Unilateral
- Trial name
- NCT04959097
- Where
- 9 sites in United States, Canada
- Volunteers
- 800 people
- Sponsor
- Children's Hospital Los Angeles
Chronic Myeloid Leukemia (CML)
Chronic Myeloid Leukemia (CML) Real-Life Database
Establish the largest possible real-life cohort collecting long-term follow-up of a maximum number of CML patients in order to carry out observational studies: epidemiological, identification of subgroups according to their…
- Trial name
- NCT05963061
- Where
- 14 sites in France
- Volunteers
- 3,500 people
- Sponsor
- University Hospital, Clermont-Ferrand
Lung Cancer
Clinico-biological Data Collection Study of Metastatic Lung Cancer
RATIONALE : Currently, the mechanisms associated with the response or resistance to treatment are poorly understood and are multifactorial.
- Trial name
- EPICURE_LUNG (NCT04944030)
- Testing
- Metastasis biopsy
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Institut Cancerologie de l'Ouest
Tuberous Sclerosis, Lymphangioleiomyomatosis
TSC Biosample Repository and Natural History Database
The TSC Biosample Repository collects and stores samples of blood, DNA, and tissues that scientists can request to use in their research. The samples we collect are all linked to clinical data in the TSC Natural History Database.
- Trial name
- NCT05676099
- Testing
- Phlebotomy, Buccal (cheek) swab, Genetic Testing
- Where
- 26 sites in United States, Canada
- Volunteers
- 5,000 people
- Sponsor
- National Tuberous Sclerosis Association
PICS, PICS-F
Post-Intensive Care Syndrome - Multicentre Prospective Registry Database of the DACH Region
Post-Intensive Care Syndrome (PICS) refers to long-term cognitive, physical, and psychological impairments that can arise after intensive care treatment.
- Trial name
- PICS-DACH (NCT07290712)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 5,000 people
- Sponsor
- Medical University of Vienna
Chronic Thromboembolic Pulmonary Hypertension
Change-a Multi-center Chronic Thromboembolic Pulmonary Hypertension （CTEPH） Database in China
The Change Database is a prospective, observational multi-center disease registry, which will collect data on patients with chronic thromboembolic pulmonary hypertension (CTEPH) in China.
- Trial name
- NCT05311072
- Testing
- pulmonary endarterectomy or balloon pulmonary angioplasty
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Gastric Cancer, Colorectal Cancer
Development and Utilization of an Integrated Clinical Genomic Database
This observational study aims to develop an integrated genomic and clinical database to support the discovery and validation of biomarkers for cancer diagnosis, treatment selection, and prediction of treatment response.
- Conditions
- Gastric Cancer, Colorectal Cancer, Lung Cancer (NSCLC), Liver Cancer
- Trial name
- SMC-4S (NCT07911267)
- Where
- South Korea
- Volunteers
- 118,750 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Chronic Pancreatitis
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis
Physicians need a tracking system for specific treatment modalities, and data to determine the impact of endoscopic ultrasound pain management for patients with chronic pancreatitis.
- Trial name
- CPN (NCT04403074)
- Testing
- Celiac Plexus Neurolysis
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Indiana University