Clinical trials: Database, open to volunteers
Mental Disorders, Healthy Control
Psychiatric Multi-omics and Neuroimaging Project
This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three.
- Trial name
- PMNP (NCT06580860)
- Testing
- Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids
- Where
- China
- Volunteers
- 1,899 people, healthy volunteers welcome
- Sponsor
- mingjun Zhong
Multiresistant Bacterial Pathogens, Virulent Bacterial Pathogens
Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens
Hypervirulent and multidrug-resistant infections are associated with significant health care costs, substantial morbidity and mortality.
- Trial name
- NCT04172025
- Testing
- Analysis of Bacterial Genome
- Where
- 5 sites in Switzerland
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Glomerular Disease, Minimal Change Disease
KOrea Renal Biobank NEtwoRk System TOward NExt-generation Analysis
Glomerulonephritis (GN) generates an enormous individual and social economic burden. However, the therapeutic options are largely based on clinical and pathological parameters and the individual response to therapy or prognosis…
- Conditions
- Glomerular Disease, Minimal Change Disease, IgA Nephropathy, Membranous Nephropathy
- Trial name
- KORNERSTONE (NCT03929887)
- Testing
- Kidney Biopsy
- Where
- 6 sites in South Korea
- Volunteers
- 3,000 people
- Sponsor
- Seoul National University Hospital
Solid Tumor, Adult
Prospective Cohort With Clinic-biologic Database of Patients Treated by Immunotherapy
ImmuCCo-1905 is a monocentric interventional study on patients treated by immunotherapy, which consist in establishment of a prospective clinic-biologic database over 5 years, associated with a biobank.
- Trial name
- ImmuCCo (NCT05223608)
- Testing
- ImmuCCo Cohort
- Where
- France
- Volunteers
- 651 people
- Sponsor
- Centre Oscar Lambret
HIV -1 Infection
Establishment of a Database of HIV Subjects Initiating or Simplifying Dual Therapy With Dolutegravir/Lamivudine
The introduction of combination antiretroviral therapy (cART) has completely revolutionized the management of HIV-positive patients, drastically reducing HIV-associated mortality and morbidity.
- Trial name
- NEW_ODOACRE (NCT06637813)
- Testing
- Blood sampling for evaluation of biomarkers
- Volunteers
- 1,220 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Neonatology
Vermont Oxford Network Very Low Birth Weight Database
Vermont Oxford Network maintains a database for live born infants <=1500 grams or <=29 weeks gestational age who are born at participating hospitals or admitted to them within 28 days of birth, regardless of where in the hospital…
- Trial name
- VON VLBW (NCT01825499)
- Testing
- Registry
- Where
- United States
- Volunteers
- 60,000 people
- Sponsor
- Vermont Oxford Network
Ehlers-Danlos Syndromes (EDS)
CLINICAL AND BIOLOGICAL DATABASE OF PATIENTS WITH NON-VASCULAR EHLERS-DANLOS SYNDROMES
The Rare Disease Reference Center (CRMR) for Non-Vascular Ehlers-Danlos Syndromes (NV-EDS) at the Raymond Poincaré University Hospital provides diagnosis and care for patients with non-vascular Ehlers-Danlos syndrome.
- Trial name
- BASE SED-NV (NCT07899489)
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bronchiectasis Adult
The BRIDGE Study - Bronchiectasis Research Involving Databases, Genomics and Endotyping
Bronchiectasis is a complex heterogeneous disorder. Treatment is challenging and many recent randomized controlled trials have been negative.
- Trial name
- BRIDGE (NCT03791086)
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- University of Dundee
Depression, Obsessive-Compulsive Disorder
Retrospective Analyses of TrakStar Database
In this study, real-world data will be used to better understand the effects patient characteristics, symptoms and TMS protocol parameters have on clinical outcomes with NeuroStar TMS.
- Conditions
- Depression, Obsessive-Compulsive Disorder, Anxiety Depression
- Trial name
- NCT06917339
- Testing
- NeuroStar Advanced TMS Therapy System
- Where
- United States
- Volunteers
- 156,000 people
- Sponsor
- Neuronetics
Breast Cancer
Bergonie Institute Breast Cancer Database
A database of breast cancer patients was established at Institute Bergonié since the 90s , to assess patients' survival, assess practice, search for prognostic factors.
- Trial name
- NCT02893761
- Where
- France
- Volunteers
- 30,000 people
- Sponsor
- Institut Bergonié
Early Gastric Cancer
Retrospective Analysis of Early Gastric Cancer Patients Based on Prospective Clinical Dataset
The goal of this retrospective observational cohort study is to describe the real-world clinicopathological characteristics, evolving treatment patterns, and long-term oncological outcomes of early gastric cancer (EGC) patients…
- Trial name
- NCT07747688
- Testing
- Clinical Data Collection
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Beijing Friendship Hospital
Cerebral Palsy
Observational Study for the Epidemiology of Cerebral Palsy in Italy
BACKGROUND AND RATIONALE Cerebral Palsy (CP) is the leading cause of childhood disability, with an estimated prevalence of 2 to 2.5 per 1,000 births.
- Trial name
- DataNetCP (NCT06813586)
- Testing
- hospital-based registry
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Fondazione Stella Maris
Healthy Related
Primary Ovarian Insufficient Patients
The Prospective Cohort Study for Primary Ovarian Insufficient Patients was set up to investigate the short- and long-term health consequences in Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University…
- Trial name
- NCT03989154
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Regional Anesthesia
Ultrasound-guided Peripheral Nerve Blocks - a Database
Peripheral nerve blocks are often used in anaesthesia. They can be used as the only method of anaesthesia during surgery or in combination with other methods, e.g., general anaesthesia and sedation.
- Trial name
- Blockbase (NCT06460792)
- Testing
- Ultrasound-guided peripheral nerve block
- Where
- Denmark
- Volunteers
- 5,000 people
- Sponsor
- Nordsjaellands Hospital
Lung Cancer
A Clinico-biological Database of Lung Cancers
This prospective, single-center, interventional study is conducted in order to achieve a biological bank accompanied by clinical data.
- Trial name
- Bio-lung (NCT03387865)
- Testing
- tissue biopsies, blood sampling, DNA banking
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Lille
Cerebrovascular Accident, Focal Infarct
Database for Stroke in Infants and Children: the International Pediatric Stroke Study
The International Pediatric Stroke Study (IPSS) was established in 2003 as a multi-center, multi-national clinical research registry.
- Trial name
- IPSS (NCT00084292)
- Where
- Canada
- Volunteers
- 12,000 people
- Sponsor
- The Hospital for Sick Children
Alport Syndrome
Eurbio-Alport (RaDiCo Cohort) (RaDiCo Eurbio-Alport)
Alport syndrome is a rare, inherited condition characterized by a combination of glomerular nephropathy progressing to kidney failure, deafness, and eye involvement.
- Trial name
- Eurbio-Alport (NCT05927467)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Glioma of Brain
Longitudinal Analysis of the Health-related Quality of Life in Glioma Patients
Gliomas are the most common primary intracranial tumors, representing at least 75% of all primary malignant brain tumors. Histopathologically, gliomas are classified into different subgroups including astrocytomas (60-70%)…
- Trial name
- Glioma2015 (NCT03849430)
- Where
- Belgium
- Volunteers
- 750 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Covid19
COVID-19 Survivorship Registry
COVID-19 is associated with acute pulmonary and cardiac injury. To better understand the degree and severity of cardiopulmonary injury as well as short and long-term sequelae of COVID-19 infection, this study will perform…
- Trial name
- NCT04527315
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Craniofacial Fibrous Dysplasia
Morbidity in Adults With Craniofacial Fibrous Dysplasia: The CRANIO-DF Study
Fibrous dysplasia is a rare bone disorder in which normal bone is replaced by fibro-osseous tissue. Craniofacial involvement may be associated with substantial morbidity and complex multidisciplinary care.
- Trial name
- NCT07870616
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Nice