Clinical trials: Deafness
Single Sided Deafness
Evaluation of Benefit for Treatment of Single Sided Deafness (SSD) Between Two Bone Conduction Prosthetic Devices; Osseointegrated Implant Versus Maxilla Anchored Removable Oral Appliance ("SoundBite")
The primary objective of this study is to compare the SoundBite™ Hearing System to surgically implanted BCD systems.
- Trial name
- NCT01933386
- Testing
- SoundBite
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Sonitus Medical Inc
Ischemic Heart Disease
Safety Study of Adenovirus Hepatocyte Growth Factor to Treat Ischemic Heart Disease
To explore the safety and efficiency of adenovirus-hepatocyte growth factor(Ad-HGF) treatment in ischemic heart disease.
- Trial name
- NCT01925352
- Testing
- Ad-HGF
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Single Sided Deafness, Conductive Hearing Loss
SoundBite Hearing System Long Term Multi Site Patient Use Study
This study is designed to collect data about the SoundBite™ Hearing System to answer specific questions. The hearing system has been cleared for commercial distribution by the Food and Drug Administration (FDA).
- Trial name
- NCT01445977
- Where
- 13 sites in United States
- Volunteers
- 150 people
- Sponsor
- Sonitus Medical Inc
Deafness, Visual Analog Pain Scale
Multicenter Trial Assessing an Innovative VAS of Pain Among Deaf People
The purpose of this study is to assess an innovative Visual Analogue Scale of pain (pictorial VAS) versus the usual VAS (VAS) among Deaf People.
- Trial name
- EVA_SOURD (NCT01423409)
- Testing
- pictorial VAS, usual VAS
- Where
- 4 sites in France
- Volunteers
- 289 people
- Sponsor
- University Hospital, Grenoble
Single Sided Deafness, Conductive Hearing Loss
SoundBite Hearing System 24 Month Multi Site Patient Use Study
The objective of this multi-site observational study is to further assess the long-term patient use of the Sonitus SoundBite Hearing System.
- Trial name
- NCT01807559
- Testing
- SoundBite Hearing System
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- Sonitus Medical Inc
Neck Pain, Unilateral Blindness
Unilateral Blindness/ Unilateral Deafness-relation to Neck Pain
Neck pain is a common complaint in the general population affecting 10-15% of the general population. females more than men. Known risk factors are: Trauma, Repetitive lifting of heavy objects at work, driving vibrating vehicles…
- Conditions
- Neck Pain, Unilateral Blindness, Unilateral Deafness
- Trial name
- NCT00589407
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Deafness
Comparison of the Bilateral Sequential and Simultaneous Cochlear Implantation in the Deaf Children
In France the indication of bilateral cochlear implant (CI) is limited to specific cases. The impact on perception and language of bilateral CI simultaneous versus sequential has to be established before discussing the…
- Trial name
- Cochleo (NCT01499901)
- Testing
- bilateral cochlear Implantation in sequential, bilateral cochlear Implantation in simultaneous
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hearing Loss, Late-Onset Hearing Loss
Genetic Testing in Detection of Late-Onset Hearing Loss
Two major limitations of existing audiometric newborn hearing screening programs are their inability to detect forms of deafness that are not expressed at birth and the low compliance with obtaining recommended audiologic…
- Conditions
- Hearing Loss, Late-Onset Hearing Loss, Deafness
- Trial name
- SoundGene (NCT00511381)
- Testing
- No intervention
- Where
- 3 sites in United States
- Volunteers
- 3,681 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Deafness
Development of Auditory Skills in Young Deaf Children With Bilateral Cochlear Implants
The primary objective to this study is to describe the auditory development and performance of young deaf children who receive bilateral implants during the first two years following device activation.
- Trial name
- NCT00604474
- Testing
- HiResolution Bionic Ear System (Cochlear Implant)
- Where
- United States
- Sponsor
- University of California, San Francisco
Hearing Loss, Extreme
Protective Effect of N-acetylcysteine Against From Ototoxicity
Peritonitis is currently one of the leading complications of continuous ambulatory peritoneal dialysis (CAPD). Aminoglycosides and vancomycin are used in the treatment of CAPD peritonitis despite their potential risk for…
- Trial name
- NCT01271088
- Testing
- N-acetylcysteine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Motor Skills in Deaf Children, Deafness
Analysis Of Equilibrium And Motor Coordination Of Deaf Children's Pre And Post Intervention Physiotherapeutic
This study aimed to assess and reassess the balance and motor skills of deaf children, passed six weeks of intervention and to verify whether a program of physical therapy intervention can match or improve motor skills.
- Trial name
- NCT01352364
- Testing
- physiotherapy intervention
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of the Sinos Valley
Severe, Profound Deafness
Balance in Children With Cochlear Implants
The purpose is to test the balance of children with unilateral,bilateral cochlear implants and patients having unilateral implants before,bilateral implants after surgery,using the Bruininks-Oseretsky Test 2nd ed.
- Trial name
- NCT00642343
- Testing
- Evaluation of motor proficiency skills., Evaluation of motor proficiency, Evaluation of motor proficiency.
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Oklahoma
Acute Coronary Syndrome
Vascular Endothelial Growth Factor (VEGF), Platelet Derived Growth Factor (PDGF), Hepatocyte Growth Factor (HGF) in Patients With Acute Coronary Syndrome (ACS)
The main aim of the study is a comparison of serum and plasma concentration of VEGF (Vascular Endothelial Growth Factor), HGF (Hepatocyte Growth Factor) and PDGF (Platelet Derived Growth Factor) with markers of myocardial injury…
- Trial name
- NCT00844987
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Melanoma
A Study of Intravenous INO-1001 Plus Oral Temozolomide to Evaluate Tolerability, Safety, and Pharmacokinetics in Patients With Melanoma
This is a prospective, open-label, non-randomized, multicenter study in adults, aged eighteen (18) or older, with newly-diagnosed or recurrent unresectable Stage III or Stage IV melanoma.
- Trial name
- NCT00272415
- Testing
- INO-1001, temozolomide
- Volunteers
- 39 people
- Sponsor
- Genentech, Inc.
Deafness
False Positive Results in Newborn Hearing Screening
The purpose of this study is to investigate the rate of false-positive results in Newborn Universal Hearing Screening Programs and it´s possible causes.
- Trial name
- NHS (NCT00753194)
- Where
- Brazil
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Deafness, Kidney Diseases
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors
The von Hippel Lindau (VHL) gene has recently been identified as the genetic defect resulting in a syndrome of multiple neoplasias.
- Conditions
- Deafness, Kidney Diseases, Kidney Neoplasms, Neoplasms
- Trial name
- NCT00001668
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Brain Mapping, Deafness
Areas of Brain Responsible for Understanding American Sign Language
The human brain is made up of two halves called hemispheres. Each half of the brain is responsible for processing different kinds of information.
- Conditions
- Brain Mapping, Deafness, Healthy
- Trial name
- NCT00001782
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sudden Deafness
Safety and Efficacy of Intratympanic Application of Dexamethasone Via Catheter in Patients With Sudden Hearing Loss
The purpose of this study is to evaluate the efficacy and safety of an intratympanic continuous two-week application of dexamethasone compared to placebo using a temporarily implanted catheter in patients with severe to profound…
- Trial name
- NCT00335920
- Testing
- Dexamethasone-dihydrogenphosphate (4mg/ml)
- Where
- 3 sites in Germany
- Volunteers
- 23 people
- Sponsor
- University Hospital Tuebingen
Coronary Artery Disease, Hypercholesterolemia
The Role of Atorvastatin on Monocyte Function in Patients With Coronary Artery Disease and Hypercholesterolemia
The aim of this study is to determine, whether an intensified atorvastatin therapy can improve monocyte function in patients with coronary artery disease and hypercholesterolemia.
- Conditions
- Coronary Artery Disease, Hypercholesterolemia, Monocyte Function
- Trial name
- NCT00329069
- Testing
- atorvastatin (drug)
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ulm