Clinical trials: Deafness
Hearing Loss, Sensorineural, Cognitive Impairment
Administration Method of Cognitive Screening in Older Individuals With Hearing Loss
The objectives of the current project aim to determine whether a more controlled amplification method or a visual administration has an effect on hearing impaired older individuals' cognitive test scores.
- Trial name
- NCT03402932
- Testing
- Auditory amplified, Visual, Auditory unamplified
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hearing Loss, Emergency Service
Hearing Impairment, Strategies, and Outcomes in Emergency Departments
Aim 1: Establish the feasibility of screening for hearing loss in the ED Aim 2: Determine the acceptability of the screening procedure (among the ED population) Aim 3: Derive a preliminary estimate of the effect size of primary…
- Conditions
- Hearing Loss, Emergency Service, Hospital Readmission
- Trial name
- Hear-VA (NCT03594500)
- Testing
- PockeTalker, No PockeTalker
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- VA Office of Research and Development
Presbycusis
Impact of Hearing Aid Service-delivery Model and Technology on Patient Outcomes
Age-related hearing loss is a big problem in the United States because many people have it and it affects their quality of life. Hearing aids can help, but not many people use them.
- Trial name
- NCT03579563
- Testing
- AUD fitting, OTC+ fitting, OTC fitting
- Where
- 2 sites in United States
- Volunteers
- 290 people
- Sponsor
- Yu-Hsiang Wu
Hearing Loss
Multi-center Study to Examine Changes to the Environment Surrounding the Electrodes in the Cochlea and to Capture the Most Challenging Listening Environments Experienced by Persons With a Cochlear Implant
This early feasibility study aims to collect pilot data on impedance measurements in real-world environments and to collect real-world and difficult listening situations and the factors impacting this, reflecting situations the…
- Trial name
- DICE (NCT06173687)
- Testing
- The impedance measurement task using the Mobile Research App (MRA)
- Where
- 4 sites in Australia, Belgium and 1 more
- Volunteers
- 51 people
- Sponsor
- Cochlear
Hearing Impairment
CROS and Quality of Life of Elderly Cochlear Implant Recipients and Their Care Givers
The purpose of this study is to assess the effect of the Naida Link contralateral routing of signal (CROS) device on speech understanding in challenging listening situations and on the quality of life in unilateral CI recipients…
- Trial name
- NCT04794179
- Testing
- Naida Link CROS
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Utah
Hearing Loss, Noise-Induced
Noise-Induced Hearing Loss-Acute Exposure Treatment
The purpose of this study is to assess the safety and efficacy of zonisamide for the treatment of noise-induced hearing loss in adults.
- Trial name
- PINIHL-AET (NCT04768569)
- Testing
- Zonisamide 100Mg Cap
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sensorineural Hearing Loss
Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss
To determine if autologous human umbilical cord blood infusion in children with acquired hearing loss is safe, feasible, improves inner ear function, audition and language development.
- Trial name
- NCT02038972
- Testing
- Autologous Stem Cells
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- James Baumgartner, MD
Hearing Loss, Hearing Loss, Sensorineural
Direct-to-Consumer Hearing Aids and Listening Effort
The aim of this proposed project is to understand whether direct to consumer (DTC) hearing aids programmed to individual hearing losses, can reduce listening effort for effective communication.
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Bilateral
- Trial name
- NCT05855005
- Testing
- DTC Hearing Aids
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cochlear Hearing Loss
Safety and Performance of Ultra/Ultra 3D Cl With HiFocus SlimJ Electrode in Adults With Severe-to-profound Hearing Loss
This is a prospective study designed to evaluate the safety and performance of the HiResTM Ultra Cl HiFocusTM SlimJ Electrode and HiResTM Ultra 3D Cl HiFocusTM SlimJ Electrode (Ultra X) under normal conditions of use as it is…
- Trial name
- NCT04929470
- Testing
- cochlear implantation
- Where
- 3 sites in Germany
- Volunteers
- 37 people
- Sponsor
- Advanced Bionics AG
Hearing Loss
Clinical Investigation of the Nucleus® CI532 Cochlear Implant
The aim of this study is to investigate the clinical benefit for patients implanted with the Nucleus® CI532 cochlear implant and to demonstrate the atraumatic nature of the electrode design.
- Trial name
- NCT02392403
- Testing
- Nucleus CI532 cochlear implant
- Where
- 8 sites in Australia, France and 2 more
- Volunteers
- 45 people
- Sponsor
- Cochlear
Meniere's Disease
Famvir for Treatment of Hearing in Unilateral Meniere's Disease
The specific aim of this study is to determine the efficacy of treatment with famciclovir in unilateral Meniere's Disease patients, specifically whether hearing can be improved.
- Trial name
- Famvir (NCT01526408)
- Testing
- Famciclovir
- Volunteers
- 11 people
- Sponsor
- House Research Institute
Alzheimer Disease, Presbycusis
Age-related Hearing Loss and Lexical Disorders
In France, Alzheimer's disease accounts for 70 to 80% of the causes of neurocognitive disorders, i.e. 600,000 to 800,000 patients.
- Conditions
- Alzheimer Disease, Presbycusis, Lexical Syntactic Disorder
- Trial name
- LOOP (NCT03638323)
- Testing
- Speech therapy
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Hearing Loss in Older Adults Study
This is a prospective, 1:1 randomized controlled trial of immediate versus delayed cochlear implantation (CI) on hearing handicap, communicative function, loneliness, mental wellbeing, and cognitive functioning.
- Trial name
- NCT03382769
- Testing
- Cochlear implantation
- Where
- 8 sites in United States
- Volunteers
- 1 people
- Sponsor
- Cochlear
Hearing Loss, Sensorineural
Remote Microphone Candidacy Study
Despite improvements in digital hearing aid technology, many hearing aid users continue to report difficulty understanding speech in challenging listening environments.
- Trial name
- NCT03897634
- Testing
- Remote Microphone
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hearing Loss, Conductive
Remote Microphone (RM) - A Comparative Study
The purpose of this investigation is to evaluate objective outcomes in pediatric bone conduction hearing device (often termed "BAHA") users with and without remote microphone (RM) technology.
- Trial name
- NCT04147611
- Testing
- BAHA, Wireless Audio Streaming Accessory, Digital Adaptive RM System
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Miami
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Optimizing Soft Speech Recognition in Children With Hearing Loss
Overhearing is important for vocabulary learning and speech and language development in young children. However, contemporary hearing aids are generally unable to provide adequate access to low-level auditory inputs from multiple…
- Trial name
- SoftSpeech (NCT05299892)
- Testing
- Phonak Audeo P or Naida P hearing aid
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Sonova AG
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Conductive Hearing Loss, Mixed Hearing Loss
Evaluation of a Hearing Device for Transmitting Sound to the Inner Ear
A single center study evaluating the performance of an externally worn sound processor for a transcutaneous bone anchored hearing system using audiological outcomes measures such as aided thresholds and self-evaluation…
- Trial name
- NCT05628285
- Testing
- Sentio 1
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Oticon Medical