Clinical trials: Death, Cardiac
Drowning, Out-Of-Hospital Cardiac Arrest
Drowning-related OHCA in Denmark: A Six-year Registry-based Study
Within a six-year period from 2016-2021, this retrospective cohort study aims to: 1) report the national incidence of drowning related OHCA's among cases attended by the Danish Emergency Medical Services (EMS), 2) assess survival…
- Trial name
- NCT05323097
- Testing
- Drowning-related OHCA
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Coronary Artery Disease, Clopidogrel Resistance
The Study of CYP2C19 Genotype-Guided Clopidogrel Treatment Models
The study purposed to learn how clopidogrel-based antiplatelet treatment for preventing adverse cardiovascular events after ePCI works in chronic coronary artery disease when guided by personal genetic characteristics for drug…
- Conditions
- Coronary Artery Disease, Clopidogrel Resistance, Coronary Thrombosis, Adverse Cardiac Events
- Trial name
- NCT06665919
- Testing
- CYP2C19 Genotype-Guided Clopidogrel Treatment, CYP2C19 Genotype Guided Antiplatelet Treatment Alternative to Clopidogrel, The Conventional Clopidogrel Treatment
- Where
- 4 sites in Georgia
- Volunteers
- 283 people
- Sponsor
- Vistamedi Ltd.
Myocardial Infarction, Ventricular Tachycardia
MAgnetic Resonance Imaging-guided implanTation of Cardioverter DEFibrillators
Implantable cardioverter-defibrillators (ICD) are currently recommended for the primary prevention of sudden cardiac death (SCD) in patients with a remote (>6 weeks) myocardial infarction (MI) and a low (≤35%) left ventricular…
- Conditions
- Myocardial Infarction, Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death
- Trial name
- SMART-DEF (NCT06269692)
- Testing
- MRI screening, Implantable Loop Recorder, Implantable Cardioverter Defibrillator
- Where
- France
- Volunteers
- 1,812 people
- Sponsor
- Central Hospital, Nancy, France
Cardiovascular Diseases
Epidemiology of Sudden Death in Cameroon
Background The burden of sudden death (SD) in sub-Saharan Africa is unknown. The aim is to assess the incidence, etiology and patient characteristics of SD in a sub-Saharan country.
- Trial name
- DOUALA-SD (NCT02031315)
- Where
- Cameroon
- Volunteers
- 240,000 people, healthy volunteers welcome
- Sponsor
- Cameroon Resuscitation Council
Ventricular Tachycardia, Ventricular Fibrillation
Pediatric Lead Extractability and Survival Evaluation (PLEASE)
This is a randomized, prospective clinical trial comparing 2 different types of implantable cardioverter defibrillator (ICD) leads in children and patients with congenital heart disease.
- Conditions
- Ventricular Tachycardia, Ventricular Fibrillation, Cardiomyopathy, Long QT Syndrome
- Trial name
- NCT00335036
- Testing
- ICD lead implant, Thin leads
- Where
- United States
- Volunteers
- 748 people
- Sponsor
- Charles Berul
Congenital Heart Disease, Coronary Artery Anomaly
European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries
Anomalous aortic origin of a coronary artery (AAOCA) is a group of rare congenital heart defects with various clinical presentations.
- Conditions
- Congenital Heart Disease, Coronary Artery Anomaly, Sudden Cardiac Death, Surgical Procedure, Unspecified
- Trial name
- EUROAAOCA (NCT06089902)
- Testing
- unroofing or other surgery if needed
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 500 people
- Sponsor
- University of Padova
Myocarditis, Ventricular Arrhythmia
Image-Based Prediction of Ventricular Tachycardias in Post-Myocarditis Patients: an International Multicenter Case-control Study
Ventricular arrhythmias (VAs) are frequently associated with structural heart diseases (SHD) such as myocardial infarction, myocarditis, and non-ischemic cardiomyopathies.
- Trial name
- MYOCARDITIS-VT (NCT06730607)
- Where
- 3 sites in Italy, Spain
- Volunteers
- 150 people
- Sponsor
- Centro Medico Teknon
Cardiovascular Death, Myocardial Infarction
Construction of a Cohort for Pan-Vascular Disease Among Employees of Taizhou People's Hospital
1. Participant Recruitment During the annual health check-ups for hospital staff, potential participants are recruited. Those who express interest are provided with a detailed explanation of the study's objectives, content, and…
- Conditions
- Cardiovascular Death, Myocardial Infarction, Stroke
- Trial name
- NCT06545799
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Jiangsu Taizhou People's Hospital
Ventilation During Resuscitation
Intra Arrest Ventilation in Human Cadavers II
The study investigates the influence of three types of ventilation mode by using Bi-Level positive airway pressure (pinsp 20 mbar, PEEP 5, AF 10/min) with two different types of ventilators ( Medumat vs.
- Trial name
- NCT06885398
- Testing
- treatment
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Muehlenkreiskliniken, MKK
Left Ventricular Function Systolic Dysfunction, Left Ventricular Function Diastolic Dysfunction
Cell Therapy in Diabetic Patients With ST-Segment Elevation Myocardial Infarction(STEMI)
The purpose of this study is to investigate the efficacy and mechanism of bone marrow mononuclear cells (BMMNC) transplantation for diabetic and non-diabetic patients with ST-segment elevation myocardial infarction (STEMI)who…
- Conditions
- Left Ventricular Function Systolic Dysfunction, Left Ventricular Function Diastolic Dysfunction, Death, Myocardial Reperfusion Injury
- Trial name
- NCT01307371
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xijing Hospital
Heart Failure, Pulmonary Disease
Advance Care Planning: A Way to Improve End-of-life Care Life Care
Communication about end-of-life issues is often suboptimal. A way to improve the quality of end-of-life care is Advance Care Planning (ACP).
- Conditions
- Heart Failure, Pulmonary Disease, Neoplasms
- Trial name
- NCT01944813
- Testing
- ACp conversation
- Where
- Denmark
- Volunteers
- 360 people
- Sponsor
- University of Aarhus
Ischemia, Cardiac Death
A Study to Evaluate Safety and Efficacy of the ExcelTM Sirolimus Eluting Stent With a Biodegradable Polymer Versus Sirolimus Eluting Stent With Non-Biodegradable Polymer in the Treatment of Patients With de Novo Coronary Artery Lesions
E.V.O.L.U.T.I.O.N.: A Randomized Study to Evaluate Safety and Efficacy of the Excel Sirolimus Eluting Stent with a Biodegradable Polymer Versus Sirolimus Eluting Stent with a Non-Biodegradable Polymer in the Treatment of Patients…
- Conditions
- Ischemia, Cardiac Death, Myocardial Infarction
- Trial name
- EVOLUTION (NCT00825773)
- Testing
- Percutaneous Transluminal Coronary Angioplasty
- Where
- China
- Volunteers
- 1,944 people
- Sponsor
- JW Medical Systems Ltd
Syncope, Bradycardia
Registry of Device Implantation
The implantable device therapy for cardiac arrhythmias has been an established therapy, and one of the common standard procedures in cardiac clinical practice.
- Conditions
- Syncope, Bradycardia, Tachycardia, Sudden Cardiac Death
- Trial name
- NCT03360227
- Testing
- implantation of cardiac devices
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Chronic Heart Failure
Evaluation of NT PRO BNP Guided Therapy on Hospitalization Rate and Mortality in Patients With Chronic HF NYHA II-IY
To use continuous measurement of NT Pro BNP level as guide in therapy patients with CHF.
- Trial name
- NCT00469001
- Testing
- Treatment according NT Pro BNP level
- Where
- Israel
- Volunteers
- 108 people
- Sponsor
- Hillel Yaffe Medical Center
Cardiac Death
Reduction of Inappropriate Implantable Cardioverter Defibrillator (ICD) Therapies in Primary Prevention Patients
The purpose of this study is to determine efficacy of a dedicated programming concept for avoidance of inappropriate implantable cardioverter defibrillator (ICD) therapies in patient with primary prevention ICD indication.
- Trial name
- DECREASE (NCT01217528)
- Testing
- device settings for group A, Device settings for group B
- Where
- 34 sites in Germany
- Volunteers
- 543 people
- Sponsor
- Abbott Medical Devices
Cardiovascular Diseases, Death, Sudden, Cardiac
Drug-Induced Sudden Death & Ventricular Arrhythmia
To investigate the relationship between the use of prescription drugs and the occurrence of ventricular arrhythmia and sudden death.
- Conditions
- Cardiovascular Diseases, Death, Sudden, Cardiac, Heart Diseases, Ventricular Arrhythmia
- Trial name
- NCT00102180
- Volunteers
- 31,000,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sudden Cardiac Death
Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac Death
This study is designed as a prospective, single-center, observational cohort study (the SMART-SCD Study, full name: Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac Death), which enrolls high-risk…
- Trial name
- SMART-SCD (NCT07476456)
- Where
- China
- Volunteers
- 421 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypertrophic Cardiomyopathy, Endothelial Dysfunction
Assessment of the Relations Between Endothelial and Venous Dysfunctions and Left Ventricular Obstruction in Genetic Hypertrophic Cardiomyopathies
Left ventricular obstruction is an invalidating complication of hypertrophic cardiomyopathies (HCM), and endothelial dysfunction has also been observed in these pathologies.
- Trial name
- HCM-Vein (NCT04129905)
- Testing
- BNP blood sample test, Electrocardiogram, Holter ECG
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Cardiac Arrest, Hypothermia
Follow up After Survived Therapy With Mild Induced Hypothermia (MIH) After Restoration of Spontaneous Circulation (ROSC)
Sudden cardiac arrest (SCA) remains one of the major leading causes of death. Cognitive deficits are common in survivors of SCA.
- Trial name
- NCT01083069
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Sarcoidosis of the Heart, Cardiomyopathy
Implantable Cardiac Defibrillators for the Prevention of Sudden Death in Patients With Cardiac Sarcoidosis
The purpose of this study is to identify patients with cardiac sarcoidosis who may be at risk for sudden death.
- Trial name
- NCT01013311
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University