Clinical trials: Debility
Diaphragm Injury, Muscle Weakness
Electromyography for Diaphragm Effort
Mechanical ventilation may be necessary to save the life of a patient due to an accident, pneumonia or surgery. The ventilator then temporarily takes over the function of the respiratory muscles.
- Conditions
- Diaphragm Injury, Muscle Weakness, Weaning Failure, Physiological Stress
- Trial name
- Edi2Pdi (NCT03580720)
- Testing
- Inspiratory threshold loading protocol
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Neostigmine, Neuromuscular Blocking Agents
Reversal of Moderate or Superficial Neuromuscular Blockade Induced by Cisatracurium
The administration of acetylcholinesterase inhibiting agents (such as neostigmine) has been used to reverse the muscle paralysis induced by non-depolarizing neuromuscular blocking agents.
- Conditions
- Neostigmine, Neuromuscular Blocking Agents, Muscle Weakness
- Trial name
- NCT04920682
- Testing
- Reversal of moderate neuromuscular blockade, Reversal of superficial neuromuscular blockade, Two-step reversal
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Strain of Fascia of Intrinsic Muscle of Foot (Disorder), Elastography
Integrated Exercise Therapy Interventions on the Performance and Injury Prevention in Competitive Sports
Football is an increasingly popular exercise and common practice among adolescent and elite athletes. However, these athletes tend to have injuries involving the lower extremity and foot.
- Conditions
- Strain of Fascia of Intrinsic Muscle of Foot (Disorder), Elastography, Muscle Weakness
- Trial name
- NCT04384003
- Testing
- Shear Wave Ultrasound Elastography, The 3-D Motion Analysis, Electromyographic
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Muscle Weakness
Facilitating Functional Independence in Patients Receiving Prolonged Mechanical Ventilation
The primary aim of this proposal is to test the effectiveness of neuromuscular electrical stimulation (NMES) in improving functional status and muscle function in patients receiving prolonged mechanical ventilation.
- Trial name
- NCT02847988
- Testing
- Neuromuscular electrical Stimulation (NMES)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- RML Specialty Hospital
Myopathy, Muscle Weakness
Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease
Visits to the emergency department (ED) for chest pain are extremely common and require a safe, rapid and efficacious treatment algorithm to exclude a possible AMI.
- Conditions
- Myopathy, Muscle Weakness, Muscle Damage, Muscle Spasticity
- Trial name
- H&M (NCT03660969)
- Where
- 5 sites in Austria, Switzerland
- Volunteers
- 797 people
- Sponsor
- University Hospital, Basel, Switzerland
Diastasis Recti, Diastasis Recti and Weakness of the Linea Alba
Tele-rehabilitation in Women With Diastasis Recti Abdominis
The aim of this randomized controlled study is to determine the effect of motor-control based telerehabilitation exercise program on inter-recti distance, abdominal endurance, pelvic floor dysfunction, and body-image perception…
- Trial name
- NCT06715059
- Testing
- Tele-rehabilitation exercise program, Home-based exercise program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Atlas University
Muscle Weakness, Syndrome; Institutionalization
Effects and Costs of Respiratory Muscle Training in Institutionalized Elderly People
The global loss of muscle mass and strength associated with aging is a cause of functional impairment and disability, particularly in the older elderly (>80 years).
- Conditions
- Muscle Weakness, Syndrome; Institutionalization, Respiratory Morbidity, Cardiovascular Morbidity
- Trial name
- NCT01759992
- Testing
- Threshold® Inspiratory Muscle Trainer (treatment).
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Valencia
Muscle Weakness, Exercise
Effect of Open Kinetic Chain Shoulder Exercises on Scapulothoracic Muscle Activity on Stable and Unstable Ground
Exercises used in shoulder rehabilitation compose of open kinetic chain and closed kinetic chain exercises.The force formed on the trunk and legs is transferred to the shoulder in open and closed kinetic chain exercises before…
- Trial name
- NCT04522531
- Testing
- Open cinetic chain shoulder exercise on unstabil ground
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Diastasis Recti and Weakness of the Linea Alba
Anatomo-radiological Study on Semilunar Line as Risk Factor fo Diastasis Recti Abdominis
Multicenter cross-sectional observational study with the aim of investigating the prevalence of diastasis recti abdominis in adults and identifying its risk factors.
- Trial name
- Semilunare (NCT05162612)
- Testing
- abtominal CT
- Where
- 2 sites in Italy
- Volunteers
- 987 people
- Sponsor
- Marta Cavalli
Old Age; Debility, Digestive Cancer
Perioperative Multicomponent Rehabilitation and Outcomes in Elderly Patients With Frailty
The study is designed to investigate the effect of a perioperative multicomponent rehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.
- Conditions
- Old Age; Debility, Digestive Cancer, Surgery, Nutrition Therapy
- Trial name
- NCT04715581
- Testing
- Preoperative nutritional optimization, Perioperative exercise training, Postoperative exercise training
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Peking University First Hospital
Stroke
Internally Versus Externally Guided Body Weight-Supported Treadmill Training (BWSTT) for Locomotor Recovery Post-stroke
The overriding goal of this proposal is to identify the critical physiological and biomechanical effects of BWSTT for promoting improved locomotor function in persons with post-stroke hemiparesis.
- Trial name
- NCT00125619
- Testing
- Locomotor training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Old Age; Debility, Age-Related Sarcopenia
Muscle Quality, Fall Concern and Lower Extremity Functionality in Older Women
The aim of the study was to investigate the effects of muscle quality on fear of fall, and lower extremity functionality in older women.
- Trial name
- NCT05758792
- Testing
- Muscle Quality Index
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Pamukkale University
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Intensive Care Unit Acquired Weakness
IMT Outcomes in Sufferers of Severe Walking Disabilities and Intensive Care Unit Acquired Weakness
Intensive care unit-acquired weakness (ICU-acquired weakness) may be caused by a variety of different causes. Several studies have shown that ICU-acquired weakness occurs in up to 30% of critically ill patients.
- Trial name
- NCT06210763
- Testing
- Threshold IMT and traditional physical therapy program, traditional physiotherapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Adult Patients, Intensive Care Unit
Functional Recovery Over the First Year After ICU Discharge
Intensive Care Unit Acquired Delirium (ICU-AD) and Intensive Care Unit Acquired Weakness (ICU-AW) are common in critically ill, mechanically ventilated adult patients.
- Trial name
- NCT04206306
- Where
- Taiwan
- Volunteers
- 407 people
- Sponsor
- National Taiwan University Hospital
Covid19, Anosmia
Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN)
The main aim of this study is to determine the effects of short-term treatment with hesperidin on COVID-19 symptoms in comparison with a placebo.
- Conditions
- Covid19, Anosmia, Fever, Cough
- Trial name
- Hesperidin (NCT04715932)
- Testing
- Hesperidin
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Montreal Heart Institute
Muscle Weakness
Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
To determine, in a double blind trial, the effects of creatine supplementation during 12 weeks on muscle mass and function of community living older women subjected to resistance training.
- Trial name
- NCT02188849
- Testing
- Resistance exercise training, Creatine
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Juvenile Idiopathic Arthritis, Rheumatic Diseases
Low-energy Laser Applications in Patients With Juvenile Idiopathic Arthritis
This study endeavored to evaluate the auxiliary effect of low-energy laser therapy (LLT) on pain, muscle performance, fatigue, and functional ability in children with juvenile idiopathic arthritis (JIA).
- Conditions
- Juvenile Idiopathic Arthritis, Rheumatic Diseases, Chronic Knee Pain, Fatigue
- Trial name
- NCT05031104
- Testing
- Physical Exercise, Physical Exercise plus Low-energy Laser Therapy
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Cairo University
Muscle Weakness Condition, Hand Grasp
Effect of Texting and Writing on Grip and Pinch Strength
Texting and writing are common hand activities among college students. Students tend to spend increasing hours of texting and writing for every day activities in addition to the academic assignments that are mainly on line and…
- Trial name
- NCT04810416
- Testing
- Texting- 10 minutes, Writing- 10 minutes, Texting- 15 minutes
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Old Age; Debility, Vaccine Hesitancy
COVID-19 Vaccination Willingness in Older Adults Based on Self-determination Theory
Introduction: The COVID-19 vaccine is an effective measure for preventing and controlling COVID-19 epidemics, and the World Health Organization lists older adults as a high-priority group for COVID-19 vaccination.
- Conditions
- Old Age; Debility, Vaccine Hesitancy, Vaccine Refusal
- Trial name
- CVWIOABOSDT (NCT06575114)
- Testing
- Self-determination theory-based health education measures
- Where
- China
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Jing-Shan Deng