Clinical trials: Decay, Dental
Dental Caries, Dental Caries Class II
Clinical Evaluation of Class II Restorations
This study aims to evaluate the one-year clinical performance of Class II restorations made with high-filling injectable and condensable universal composite resins. The study included 71 patients and 140 restorations.
- Trial name
- NCT06346756
- Testing
- Treatment of dental caries.
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Dental Caries, Minimally Invasive
Sealing Defective Margins of Composite Restorations With Fluid Composite Resin Nanofiller Reinforced
the patient (n=60), with at least 3 composite resins with marginal defects , randomized into 3 groups A=Sealed with flow composite reinforced with nanofiller , B= Sealed with resin sealant , and C=Control, without intervention …
- Conditions
- Dental Caries, Minimally Invasive, Repair
- Trial name
- SEAL2 (NCT03214445)
- Testing
- Sealing margins with flow composite, Sealing margins with seal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Chile
Severe Early Childhood Caries, Dental Caries
Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children
This observational study aims to evaluate the relationship between salivary antimicrobial peptides and severe early childhood caries (S-ECC) in Turkish children.
- Trial name
- NCT07414030
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dental Caries Secondary to Polymorphisms, Polymorphisms in Enamel Encoding Genes
Polymorphisms in ENAM, AMBN, and KLK4 Contribute to DCS.
A Cross-Sectional Study aims to shed light on potential genetic determinants influencing dental caries susceptibility within this demographic and significantly understanding of genetic factors associated with dental caries…
- Trial name
- NCT06343766
- Testing
- DNA collation and genotyping
- Where
- Egypt
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Amina Fouad Farag
Dental Caries
Enamel Caries in Orthodontic Patients
This randomized double-blind two arm controlled clinical trials evaluates the hypothesis that the regular use of a tooth paste containing microcrystalline hydroxylapatite provides a caries preventive effect in caries-susceptible…
- Trial name
- ECOP (NCT02705456)
- Testing
- Tooth Brushing HA, Tooth Brushing FL
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
HIV-1
Fuzeon Viral Decay Pilot Study
In order to better understand the source(s) and the mechanism(s) of HIV persistence and to potentially lead to further suppression of HIV from viral reservoirs, we propose to examine the effect of co-administration of…
- Trial name
- NCT00334022
- Testing
- enfuvirtide
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Canadian Immunodeficiency Research Collaborative
Dental Caries, Child Neglect
Improving Family's Adherence to Dental Care After DGA (HECC-CAN-study)
Early childhood caries (ECC) is a common disease. Its prevalence is highest in poor, socially disadvantaged, and minority groups. Dental treatment under General Anaesthesia (DGA) is common, especially among the youngest patients.
- Trial name
- HECC-CAN (NCT04898465)
- Testing
- Social Paediatric Intervention
- Where
- Finland
- Volunteers
- 89 people
- Sponsor
- Helsinki University Central Hospital
Initial Caries, Arrested Dental Caries
Early Caries Lesion Management Observational Study
The purpose of this observational study is to assess the effectiveness of Curodont Repair Fluoride Plus (CRFP) compared to other tooth-specific treatments (silver diamine fluoride (SDF), sealants, or other FDA-approved…
- Conditions
- Initial Caries, Arrested Dental Caries, Cavitated Caries, Dental Caries
- Trial name
- ELMO (NCT04933331)
- Testing
- Curodont Repair Fluoride Plus, Silver Diamine Fluoride, Glass Ionomer Sealant
- Where
- 4 sites in United States
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- CareQuest Institute for Oral Health
Caries,Dental
Caries Detection With Two Different Caries Detecting Devices
The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression.
- Trial name
- NCT06152081
- Testing
- LumiCare rinse, QLF Inspektor Pro Imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tufts University
Dental Caries
Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH
The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.
- Trial name
- NCT01569165
- Testing
- cleansing teeth after topical fluoride therapy
- Where
- Iran
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Dental Caries
Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes
The purpose of this study is to investigate the efficacy of different sodium fluoride (NaF) containing toothpastes in prevention of dental caries.
- Trial name
- NCT00708305
- Testing
- Sodium Fluoride (NaF)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries
Consumption of Probiotics on Salivary Bacteria Causing Dental Caries
Dental caries is a multifactorial disease effecting majority of the human population.One of the etiological factor causing dental caries is salivary mutans streptococci.
- Trial name
- NCT02752594
- Testing
- probiotic
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sharda University
Dental Caries in Children
Isolation of the Operative Field Influences the Survival Rate of Composite Restorations
The aim of this study was to evaluate the survival of direct composite resin restorations in primary molars using different methods of isolation of the operative field: absolute isolation (local anesthesia, use of dental clamp…
- Trial name
- IsolationC3 (NCT03733522)
- Testing
- Rubber dam isolation, Relative isolation
- Where
- Brazil
- Volunteers
- 93 people
- Sponsor
- University of Sao Paulo
Gastroesophageal Reflux Disease, Severity
Association Between Gastroesophageal Reflux Disease (GERD) Severity and Dental Caries
This study aimed to assess the relationship between gastroesophageal reflux disease (GERD) severity (based on upper gastrointestinal endoscopy) and dental caries severity.
- Conditions
- Gastroesophageal Reflux Disease, Severity, Dental Caries
- Trial name
- NCT07108751
- Testing
- Endoscopy
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dental Caries
Prevelance of Dental Caries in Agroup of Egyption Children Using Caries Assessment Spectrum and Treatment
To explore the prevalence of dental caries in Egyptian children aged from 6 to 9 years oldusing CAST index and DMFT index
- Trial name
- NCT04285931
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Bleeding on Probing
Evaluating Methods of Dental Health Instructions on the Oral Health Indices of 12-18-year-old Patients With Fixed Orthodontics
The goal of this clinical trial is to learn which type of oral health education works best to help 12-18-year-old participants with fixed orthodontic appliances (braces) keep their mouths healthy.
- Conditions
- Dental Caries, Bleeding on Probing, Gingival Index, Plaque Index
- Trial name
- NCT07667283
- Testing
- Verbal Oral Hygiene Instruction, Pamphlet-Based Oral Hygiene Instruction, Video-Based Oral Hygiene Instruction
- Where
- Iran
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Dental Caries
Use of Antibacterial Cement in Infected Dentin
Dental materials with antibacterial properties can prevent the harmful effects caused by oral cariogenic bacteria. This double-blind controlled clinical trial evaluated the performance of antibacterial cement for sealing infected…
- Trial name
- AC (NCT01449136)
- Testing
- Antibacterial cement
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Pernambuco
Autism Spectrum Disorder, Dental Caries
Using Video Modeled Social Stories to Improve Oral Hygiene in Children With Autism Spectrum Disorder
We hypothesize that oral hygiene habits in children 8-12 years of age can be improved using video format Social Story intervention techniques.
- Trial name
- NCT02003820
- Testing
- video modeled social story
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Yale University
Dental Caries
AI-Based Detection of Dental Caries in Children
This study aims to evaluate the effects of an artificial intelligence (AI)-based caries detection system on the diagnosis and categorization of dental caries in pediatric patients.
- Trial name
- NCT06984029
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Noura Nageh Ramadan Ahmed
Helicobacter Pylori Infection
Influence of Oral Hp Infection and Oral Related Factors on Gastric Hp Infection and Eradication Therapy
Helicobacter pylori (H. pylori) is closely related to the occurrence of gastric cancer and other diseases. The discovery and eradication of H. pylori is of great significance for the prevention and treatment of related diseases.
- Trial name
- Hp (NCT05455372)
- Testing
- PPI quadruple therapy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
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