Clinical trials: Decay, Dental
Dental Hypersensitivity
Association of Two Desensitizing Protocols to Control Dentinal Hypersensitivity in Non-carious Lesions
This randomized, double-blind clinical trial evaluated the effect of photobimodulation associated with 8% strontium acetate in the treatment of dentin hypersensitivity in non-carious lesions and analyzed the risk factors with the…
- Trial name
- NCT04642001
- Testing
- Photon Laser III-DMC (without radiation emission) + My First- Colgate, Photon Laser III-DMC (without radiation emission) + Sensodyne® Rapid Relief / GSK, Photon Laser III-DMC (with irradiation emission) + My First- Colgate
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dental Caries
Oral Alkali Production and Caries Prevention in Children (Cross-sectional Component)
The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management.
- Trial name
- NCT02368028
- Testing
- Oral Samples
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Florida
Caries, Dental, Local Anesthesia
Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients
This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children…
- Conditions
- Caries, Dental, Local Anesthesia, Inferior Alveolar Nerve Block, Dental Anxiety
- Trial name
- NCT07133919
- Testing
- AI-Assisted Child-Friendly Communication, Traditional Behavior Management Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dental Caries
Fluoride Varnish in the Prevention of Dental Caries in Aboriginal and Non-aboriginal Children
The purpose of this study is to determine whether semi-annual fluoride varnish applications combined with caregiver counseling are effective in preventing and reducing a severe form of dental decay, known as early childhood…
- Trial name
- NCT00435500
- Testing
- Fluoride varnish
- Where
- Canada
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dental Caries Class II, Marginal Integrity of Composite Restorations With Universal Adhesives
One-Step Universal Adhesives: A 3-year Clinical Trial in Class II Composite Restorations
to evaluate and compare the clinical performance and periodontal responses of four commercially available one-step universal adhesives with different formulations in Class II composite restorations over a three-year period.
- Trial name
- NCT06265116
- Testing
- One-step universal adhesive
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries, Dental Plaque Index
Antimicrobial Effect of Curcumin Versus Chlorohexidine on Oral Microbiome
Dental caries, one of the world's most common infectious diseases, is a biofilm-mediated, sugar-driven, dynamic disease. It has an impact on physical, mental, and social health and is extremely costly to society.
- Conditions
- Dental Caries, Dental Plaque Index, Oral Microbiome
- Trial name
- NCT06847984
- Testing
- Curcumin, Chlorohexidine
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Dental Caries in Children
Pain Assessment During Chemo-Mechanical and Smart Burs Caries Removal Versus Atraumatic Restorative Treatment in Carious Primary Molars
The aim of the clinical trial is to assess pain during Atraumatic Restorative Treatment (ART), Smart Burs and Chemo-mechanical Caries Removal (CMCR) in primary molars.
- Trial name
- NCT05529433
- Testing
- Atraumatic Restorative Treatment (ART), Smart Burs, Chemo-Mechanical Caries Removal (CMCR)
- Volunteers
- 33 people
- Sponsor
- Cairo University
Dental Caries
Alkaline Water and Salivary Bacterial Count
This study will be aimed to examine the effect of alkaline water on salivary streptococcus mutans bacteria which is the main cause of dental caries and comparing its effect with chlorohexidine mouthwash on the children aged…
- Trial name
- NCT06511336
- Testing
- Alkaline water (FLO water- Bottled drinking water- the Egyption Saudi Company for natural water- made in Egypt
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Dental Caries
ETT Rotation During Nasal Fiberoptic Intubation
A nasal endotracheal tube (ETT) is routinely placed in children and a fiberoptic scope (FOS) is commonly used for this purpose. Resistance to the passage of ETT is frequently encountered as it is advanced over the FOS for…
- Trial name
- NCT02405546
- Testing
- Pre-Rotated (Group R), No pre-rotation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Congenital Heart Defect, Dental Caries in Children
Oral Health Intervention Program for Children With Congenital Heart Defects
Background: Children with congenital heart defects (CHD) are reported to have poorer oral health compared with healthy children.
- Conditions
- Congenital Heart Defect, Dental Caries in Children, Dental Erosion, Dental Plaque
- Trial name
- NCT03311438
- Testing
- Oral health intervention program
- Volunteers
- 75 people
- Sponsor
- University of Bergen
Dental Caries
An in Vitro Evaluation of Antimicrobial Photodynamic Therapy on Deciduous Carious Dentin
Despite of the decline of dental caries, this disease is still common in polarized groups affecting children. Therefore, the aim of this randomized blind in vivo study was to compare the antimicrobial effect of two antimicrobial…
- Trial name
- NCT02479958
- Testing
- Rubber dam isolation, Tooth drying, Dentin wash with chlorhexidine 2%
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Vitamin D Deficiency, Dental Caries
Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children
The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.
- Conditions
- Vitamin D Deficiency, Dental Caries, Dental Enamel Hypoplasia
- Trial name
- NCT03273725
- Testing
- Dental examination including taking a saliva sample.
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Tannhelsetjenestens Kompetansesenter Midt-Norge
Dental Caries
Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial
This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years.
- Trial name
- NCT07612540
- Testing
- phosphoric acid pretreatment
- Where
- 3 sites in Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Fluorosis
Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes
Fluoride toothpaste has been associated not only with declining dental caries prevalence but also with an increase in dental fluorosis.
- Trial name
- NCT01589991
- Testing
- Toothpaste
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Caries, Insufficient Dental Filling
A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth
The overall aim of this clinical investigation is to assess the clinical performance and safety of composite restorations cured with fast curing mode (5 seconds with 2000 mW/cm²) in primary molars.
- Trial name
- NCT07212660
- Testing
- Fast curing mode, Conventional curing mode
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Dental Caries, Unsatisfactory or Defective Restoration of Tooth
Clinical Investigation of the F-Composite 2 System in Direct Filling Therapy
The objective of this study is to evaluate the clinical performance of F-Composite 2 system in Class I and Class II cavities in permanent teeth.
- Trial name
- NCT03221660
- Testing
- F-Composite 2 system
- Where
- Liechtenstein
- Volunteers
- 50 people
- Sponsor
- Ivoclar Vivadent AG
Dental Caries
Clinical Performance of a Glass-ionomer Restorative System: A 6-year Evaluation
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in class I and class II cavities.
- Trial name
- NCT02888912
- Testing
- EQUIA, Gradia Direct Posterior
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Bottle Feeding, Dental Caries in Children
Controlling ECC and Terminating Bottle-feeding Habits Among Toddlers Using a Modified Oral Care Package
This study will evaluate the effectiveness of oral health promotion in the prevention of ECC (early childhood caries) in bottle-fed children.
- Trial name
- NCT04440137
- Testing
- Bottle-feeding cessation program
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Caries, Dental, Tooth Decay
Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations
This is a clinical study evaluating a new dental product called Solventum™ Vitrebond™ Pulp Protect Liner/Base. This new product is designed to be used as a liner or base between the tooth and the dental filling, as well as for a…
- Conditions
- Caries, Dental, Tooth Decay, Dental Decay, Tooth Sensitivity
- Trial name
- NCT07261137
- Testing
- Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Solventum US LLC
Primary Dental Caries
Detection of Residual Caries on Class II Cavity Walls in Primary Teeth Following Atraumatic Restorative Treatment (ART)
The primary aim of this study is to compare the diagnostic agreement and effectiveness of three different methods-Fluorescence-Aided Caries Excavation (FACE), caries detection dye, and clinical observation-in detecting residual…
- Trial name
- NCT07250022
- Testing
- FACE + Caries Detection Dye, FACE + Visual-Tactile Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
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