Clinical trials: Decay, Dental
Decay, Dental, Caries Class II
Clinical Performance of Short Fiber Reinforced Flowable Resin Composite Restorations 2y RCT
Clinical performance of short fiber reinforced flowable resin composite restorations versus conventional resin composite restorations will be tested in posterior teeth (2y randomized clinical trial).
- Trial name
- NCT04720638
- Testing
- Short fiber reinforced flowable resin composite restorations, Conventional resin composite restoration
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental, Apical Periodontitis
Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine…
- Trial name
- NCT04105985
- Testing
- Kovanaze Nasal Spray, Articaine Injection
- Sponsor
- Virginia Commonwealth University
Extensive Decay in Primary Molars
Comparison of The Success Rates of Four Different Pulpotomy Techniques
This randomized clinical trial was conducted to examine and compare the effectiveness of pulpotomy in primary molars treated with calcium silicate based materials including Biodentine and two different mineral trioxide aggregate…
- Trial name
- NCT03135626
- Testing
- Biodentine, ProRoot (Aggregate), MTA Plus
- Volunteers
- 38 people
- Sponsor
- Istanbul University
Dental Caries
Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child
Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy. Hypothesis: the administration of probiotics during infancy has no effect on future dental health.
- Trial name
- NCT01424852
- Testing
- Probiotics in infant milk formula
- Where
- Finland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Turku
Reversible Pulpitis, Pulpitis
Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer
The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group…
- Conditions
- Reversible Pulpitis, Pulpitis, Caries,Dental, Caries Class I
- Trial name
- NCT04365270
- Testing
- Glass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
Yakima Head Start Fluoride Varnish Study
The aim of this study is to determine whether an annual application of three (3) fluoride varnish doses over two weeks is at least as effective in reducing cavities as the current semi-annual application.
- Trial name
- NCT00067353
- Testing
- Fluoride varnish
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Caries, Inlays
Ceramic Versus Composite in the Treatment of Posterior Teeth by Inlays or Onlays
The main purpose of this trial is to determine which material, between ceramic and composite, is best to manufacture dental inlays and onlays in the treatment of moderate dental substance losses, generally due to dental caries.
- Trial name
- CECOIA (NCT01724827)
- Testing
- ceramic (Empress CAD, Ivoclar Vivadent), composite (Lava Ultimate, 3M Espe)
- Where
- 6 sites in France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dental Caries
Evaluation in Vivo of Mouthwash With Nanoencapsulated Fluoride
The literature recognizes that fluoride is the most widely used and studied means for dental remineralization. The use of fluoride mouthwashes is shown as an effective way to increase the fluoride intraoral availability.
- Trial name
- NCT05143086
- Testing
- Mouthwash 100% Nano-F, Mouthwash 50% Nano-F, Mouthwash standard
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Fabio Correia Sampaio
Decayed Teeth
Morphological Root Canal Variation in C-shaped Canal Will be Assessed for Age by Using Cone Beam Computed Tomography
CBCT Data Of C-Shaped Canal In Mandibular Second Molar Will Be Assessed For Age.
- Trial name
- NCT04817852
- Testing
- CBCT data of c-shaped canal in mandibular second molar.
- Where
- India
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CSI College of Dental Sciences and Research, Madurai
Dental Caries in Children, Pediatric Dental Sedation
Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 Years
The primary objective of this randomized controlled trial is to assess the effects of oral sedation using midazolam and hydroxyzine with and without meperidine (a narcotic) on sedation outcomes in pediatric dental patients…
- Conditions
- Dental Caries in Children, Pediatric Dental Sedation, Meperidine, Hydroxyzine
- Trial name
- NCT04068948
- Testing
- Meperidine, Hydroxyzine, Midazolam
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Caries
Effect of a Sugar-Free Chewing Gum Containing Magnolia Bark Extract on Caries Lesions in Healthy Adult Volunteers
The effect of chewing gums containing MBE and xylitol on different variables related to caries and gingivitis in a sample of adult volunteers with a high risk for caries will be evaluated.
- Trial name
- NCT02310308
- Testing
- Chewing gum administration
- Where
- 2 sites in Italy
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Dental Caries
Clinical Study 3MESPE Crowns CR15/02
This clinical study seeks to address four independent questions that are all part of the delivery of care associated with the provision of a single item of treatment; an indirect restoration (known as a 'crown') to restore and…
- Trial name
- NCT02735304
- Testing
- Impression intervention
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Dental Caries in Children, Pediatric Patients
Relationship Between Tooth Decay and Trabecular Bone
Chewing, a movement that matures with experiences, has effects on the growth and development of the stomatognathic system. Tooth decay, which is known to have effects on chewing, can affect the jaw bone due to its indirect effect…
- Conditions
- Dental Caries in Children, Pediatric Patients, Radiology
- Trial name
- NCT04608526
- Testing
- Fractal analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Carious Lesion
Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity
Type of study: Randomized Clinical trial To compare post-restorative sensitivity between titania nanoparticle reinforced bonding agent and bonding agent without nanoparticles in posterior composite restorations.
- Trial name
- NCT05744648
- Testing
- Composite resin restoration using Titania nanoparticle reinforced bonding agent, Composite resin restoration without Titania nanoparticle incorporated bonding agent
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Tooth Decay
Clinical and Radiographic Evaluation of Alkasite Restorative Material Versus Glass Ionomer Cement
To evaluate the clinical and radiographic performance of Alkasite restorative material versus glass ionomer in restoration of primary molars.
- Trial name
- GIC (NCT06195449)
- Testing
- ALKASITE RESTORATIVE MATERIAL, Glass Ionomer Cement
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
HIV Infections
New Era Study: Treatment With Multi Drug Class (MDC) HAART in HIV Infected Patients
This is a multi-center, open-label, non-randomized proof-of-concept trial. Two cooperating HIV-specialized centres represented by Dr. med. Hans Jaeger and Prof. Dr.
- Trial name
- NewEra (NCT00908544)
- Testing
- PHI-patients, CHI-patients
- Where
- 8 sites in Germany
- Volunteers
- 47 people
- Sponsor
- MUC Research GmbH
Dental Caries, White Spot Lesions
QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment
This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS…
- Conditions
- Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization
- Trial name
- NCT07608471
- Volunteers
- 30 people
- Sponsor
- Universidad El Bosque, Bogotá
Plaque Ph Lowering After Use of Probiotics, Caries
Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study
The aim of the present research protocol was to evaluate the effect of probiotics daily used, on the plaque acidogenicity of children.
- Conditions
- Plaque Ph Lowering After Use of Probiotics, Caries, Gingivitis
- Trial name
- NCT01601145
- Testing
- consumption of lozenges
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- Università degli Studi di Sassari
Dental Caries
Family-centered Oral Health Promotion for New Parents
Early childhood caries (ECC) is a global health problem that causes pain and infection to the children affected. It is a common disease among preschool children in Hong Kong.
- Trial name
- NCT02937194
- Testing
- Personal oral health instruction + pamphlets distribution, Pamphlets distribution
- Where
- China
- Volunteers
- 580 people
- Sponsor
- The University of Hong Kong
Dental Caries, Dental Caries in Children
Atraumatic Versus Silver-Modified Atraumatic Restorative Treatment in Primary Molars
The goal of this clinical trial is to evaluate and compare the short-term effectiveness of two minimally invasive treatments-Atraumatic Restorative Treatment (ART) and Silver-Modified Atraumatic Restorative Treatment (SMART)-in…
- Trial name
- NCT07023939
- Testing
- ART: Atraumatic restorative treatment, SMART: Silver-Modified Atraumatic Restorative Treatment
- Where
- Lebanon
- Volunteers
- 34 people
- Sponsor
- Beirut Arab University
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