Clinical trials: Decayed Teeth
Incipient Caries
Clinical and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride, With or Without Application of LED, in Arresting Incipient Permament Molar Caries
The study aims to compare the effect of international brand ammonia based 38% SDF, water based silver fluoride solution (AgF), an aqueous silver fluoride solution, and local brand ammonia based SDF with and without LED light…
- Trial name
- SDF and AgF (NCT07366645)
- Testing
- International Sliver Diamine Fluoride, Local brand Egyptian Silver Diamine Fluoride, Silver Fluoride
- Volunteers
- 366 people
- Sponsor
- Cairo University
Juvenile Idiopathic Arthritis, Gingivitis
Clinical and Biochemical Evaluation of Dental and Periodontal Conditions in Children With Juvenile Idiopathic Arthritis
Aimed to be done in the planned thesis to evaluate the dental and periodontal health of patients with newly diagnosed JIA and healthy-periodontal problems with cytokines from saliva and oxidative stress markers non-invasively…
- Conditions
- Juvenile Idiopathic Arthritis, Gingivitis, Decay, Dental
- Trial name
- NCT05217277
- Testing
- Humans ELISA kits
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries, Obesity Risk
Mothers' Action Project for Child Health
This randomized controlled trial will recruit Bangladeshi mothers and their young children into a 12 month intervention that provides child health and oral health education and seeks to build social networks among mothers.
- Trial name
- MAP-CH (NCT06753669)
- Testing
- health education and social network building, dental referral and educational materials
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Dental Caries, Cervical Caries
The Effectiveness RMGI and Giomer, Individually and Combined Anterior Cervical Caries
This study compares the effectiveness of three dental materials for restoring anterior cervical caries in high-risk patients: resin-modified glass ionomer (RMGI), Giomer, and a combination technique where RMGI is veneered with…
- Trial name
- NCT06901453
- Testing
- Low shrinkage Giomer restorative material (Beautifil II LS), RMGI alone - Control
- Volunteers
- 75 people
- Sponsor
- Cairo University
Dental Caries in Children, Dental Plaque
Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases
The aim of the study is to identify adolescent patients that are at risk of developing oral diseases, and to assess if targeted preventive oral treatment with antibacterial dual-light therapy as an adjunctive treatment method can…
- Conditions
- Dental Caries in Children, Dental Plaque, Tooth Decay, Periodontitis
- Trial name
- LumoPrevent (NCT06286501)
- Testing
- Lumoral Treatment, Standard, personalized oral health care
- Where
- Finland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wellbeing Services County of Pirkanmaa
Dental Caries
Waukesha Smiles: Dental Outreach to Low-income Waukesha Children
The Waukesha Smiles Project will compare approaches to improve oral health habits and increase access to basic dental care for low-income children in Waukesha, Wisconsin through a school-based outreach program of oral health…
- Trial name
- NCT00703001
- Testing
- Educational Intervention, Referral Intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Cervical Caries
Clinical Evaluation of Self-Adhesive Flowable Giomer With and Without Selective Enamel Etching
This randomized clinical trial is to evaluate the clinical performance of the self-adhesive flowable Giomer with and without selective enamel etching compared to flowable Giomer using standard bonding protocol in class V cavity…
- Trial name
- NCT07575646
- Testing
- Beautifil Flow Plus F00, FIT SA after selective enamel etching, FIT SA
- Volunteers
- 75 people
- Sponsor
- Cairo University
Dental Caries, Teeth Loss
Impact of the Radiographic Examination on Diagnosis and Treatment Decision of Caries Lesions in Primary Teeth
Radiographs have been used to aid dentists in detecting the presence of cavities in the deciduous teeth of children. This procedure is globally recommended because the conventional clinical examination usually overlooks some…
- Conditions
- Dental Caries, Teeth Loss, Quality of Life
- Trial name
- CARDEC-1 (NCT02078453)
- Testing
- Dental treatment
- Where
- Brazil
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Caries Risk, Caries, Dental
Powered vs Manual Toothbrush Use: Its Effect on Caries Risk in Pre-Adolescents
This pilot study aims to evaluate dental caries experience in children ages 8-12 years old through comparing the use of a powered versus manual toothbrush, while using a standardized fluoride toothpaste as the control over the…
- Trial name
- NCT07859553
- Testing
- Powered toothbrush
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Dental Caries Class v
Evaluation of the Marginal Integrity of Recent Bulk Fill Flowable Composite vs Glass Ionomer for Carious Cervical Restorations: RCCT
The study will be conducted to assess the marginal integrity of different types of restorations (ketac ™ N100 - ketac™ Universal and bulk fill flowable composite) in class v restoration using USPHS criteria.
- Trial name
- NCT04053530
- Testing
- restorative materials
- Where
- 2 sites in Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Caries
Clinical Performance of Short Fiber Reinforced Resin Modified Glass Ionomer Restorations in Cervical Carious Teeth (1y Randomized Clinical Trial)
This research proposal is introduced to clinically test short fiber reinforced glass ionomer material from GC Europe due to gap of knowledge present in this area.
- Trial name
- NCT06185881
- Testing
- restoration of cervical carious teeth
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Decay, Dental, Impacted Third Molar Tooth
Risk Factors for Distal Caries of Second Molars Adjacent to Mandibular Impacted Third Molars
Distal surfaces of second molars adjacent to wisdom teeth are always at risk for caries and external root resorption. The incidence of caries is high, especially in partially impacted third molars in mesioangular and horizontal…
- Trial name
- NCT06017570
- Testing
- Radiologic examination on orthopantomogram, Clinical examination after surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Selcuk University
PreTerm Birth
Prevalence of Dental Caries in Preterm Birth Children Aged 2-5 Years in Primary Dentition
The purpose of the study is to determine the prevalence of dental caries in preterm birth children aged 2-5 years in primary dentition.
- Trial name
- NCT02999061
- Where
- Egypt
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy Related, Dental Caries
The Effects of Pregnancy on Oral Health
The aim of this study was to evaluate the effects of pregnancy on salivary pH, flow rate, caries experience and periodontal status.
- Conditions
- Pregnancy Related, Dental Caries, Periodontal Diseases, Saliva Altered
- Trial name
- NCT06343337
- Testing
- Evaluation of DMFT index, CPI scores, salivary pH and flow rate in pregnant and non-pregnant woman
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Pain During Caries Excavation
Comparison of Intraoperative Pain Perception During Caries Excavation Using Smart Burs and Carisolv to Conventional Diamond Burs
The goal of this randomized controlled trial is to compare the amount of pain experienced during removal of dental caries using Smart burs, Carisolv, and conventional diamond burs in adults aged 18-45 years with active caries in…
- Trial name
- NCT07869407
- Testing
- polymer burs, Carisolv, Conventional Diamond Burs
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Rehman Medical Institute - RMI
Dental Caries Pit and Fissure, Dental Caries in Children
Occlusal Caries Management in First Permanent Molars in Child Dental Care
Occlusal caries management in first permanent molars: a pragmatic randomized clinical trial in child dental care Aim of the present study is to evaluate the effectiveness of fissure sealants and fluoride varnish in a pragmatic…
- Trial name
- FISSURE (NCT03315312)
- Testing
- Fluoride Varnishes, Fissure Sealants
- Where
- Norway
- Volunteers
- 410 people
- Sponsor
- Oral Health Centre of Expertise in Eastern Norway
Dental Caries Tooth Demineralization, Early Childhood Caries (ECC)
Effects of Calcium-Containing Oral Sprays on Fluorescence-Detectable Plaque Area in Children
This exploratory randomized clinical trial aimed to evaluate the effects of calcium-containing oral sprays on the primary clinical outcome, fluorescence-detectable plaque-associated area measured by quantitative light-induced…
- Trial name
- NCT07269730
- Testing
- oral spray
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Caries, Dental
Health Effects of Silver-Mercury Dental Fillings
The purpose of this study is to determine whether there are detectable health effects of low-level mercury exposure (from normal exposure to mercury-containing dental fillings) in the known target organs/systems affected by…
- Trial name
- NCT00066118
- Testing
- Dental amalgam restorations
- Where
- United States
- Volunteers
- 507 people
- Sponsor
- University of Washington
Dental Caries
Effectiveness of Sealing Dental Caries
This study aims to evaluate, through a controlled clinical randomized study, the effectiveness of sealing carious lesions with composite resin in primary molars.
- Trial name
- NCT02584218
- Testing
- Non-invasive resin based caries sealing, Invasive resin based restoration
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Attention Deficit Hyperactivity Disorders, Caries, Dental
Salivary Bacteria and Oral Health Status in Children With ADHD
Attention deficit and hyperactivity (ADHD) affect 6% of school-aged children. Few studies reported higher prevalence of caries and restorations among children with ADHD. Methylphenidate is the drug of choice to treat ADHD.
- Conditions
- Attention Deficit Hyperactivity Disorders, Caries, Dental, Xerostomia
- Trial name
- ADHD (NCT00966394)
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization