Clinical trials: Decayed Teeth, open to volunteers
Periodontitis, Gingivitis
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : improved dental health reduced risk of pneumonia better glucose…
- Conditions
- Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections
- Trial name
- NHOralHealth (NCT06890676)
- Testing
- Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Missouri Department of Health and Senior Services
Dental Caries
Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial
This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years.
- Trial name
- NCT07612540
- Testing
- phosphoric acid pretreatment
- Where
- 3 sites in Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Sequential PVP-I and FV
This prospective cohort study in children will determine if: topical povidone iodine 10% followed by topical fluoride varnish is superior to placebo iodine followed two different varnishes alone to prevent tooth decay (dental…
- Trial name
- NCT07683910
- Testing
- fluoride varnish, 2.5%, topical fluoride, 2.1%, Povidone Iodine Topical
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Dental Caries, Insufficient Dental Filling
A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth
The overall aim of this clinical investigation is to assess the clinical performance and safety of composite restorations cured with fast curing mode (5 seconds with 2000 mW/cm²) in primary molars.
- Trial name
- NCT07212660
- Testing
- Fast curing mode, Conventional curing mode
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Caries,Dental
Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars
Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries…
- Trial name
- NCT06826456
- Testing
- sub-ablative Er,Cr:YSGG laser, Fluoride varnish application
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Caries in Children
Different Luting Cements for Pediatric Zirconia Crowns
The study aims to compare the efficacy of using bioactive cement versus resin-cement for cementation of anterior pediatric zirconia crowns.
- Trial name
- NCT07152561
- Testing
- Zirconia crown cemented with Predicta® Bioactive Cement, Zirconia crown cemented with resin-cement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Er:YAG Laser for Dental Cavity Preparation
The goal of this clinical trial is to compare Er:YAG laser cavity preparation with conventional rotary instruments in adults who have permanent premolars planned for extraction as part of orthodontic treatment.
- Trial name
- NCT07831720
- Testing
- Er:YAG Laser, Conventional Rotary Cavity Preparation
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ho Chi Minh City Odonto-Stomatology Hospital
Dental Caries, Class II Dental Caries
Clinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite
Introduction: Resin-based composites (RBCs) have become the gold standard in restorative dentistry due to their superior aesthetics, adhesion, and minimally invasive application.
- Trial name
- NCT07262086
- Testing
- Resins, Composite nanohybrid, Resins, Composite bioactive
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Class II Dental Caries, Dental Caries
Comparison of the Functional Properties of Two Injectable Materials in Posterior Teeth: Randomized Clinical Trial
Using two different injectable materials in class II cavities to compare functional properties
- Conditions
- Class II Dental Caries, Dental Caries, Injectable Composite
- Trial name
- NCT06894186
- Testing
- Gaenial universal injectable
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Dental Caries, Periodontitis
Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets
This study aims to understand how oral bacteria that cause tooth decay and gum disease spread among family members and whether treating multiple family members can reduce the return of these bacteria after dental treatment.
- Conditions
- Dental Caries, Periodontitis, Oral Microbiome, Bacterial Transmission
- Trial name
- NCT07674888
- Testing
- Professional Dental Plaque Disruption
- Where
- Canada
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Composite Resins, Dental Caries Class II
Bulk-Fill Composite Restorations: Clinical Evaluation
This randomized controlled clinical study aims to evaluate the clinical performance of five different bulk-fill composite materials representing distinct technological approaches according to the World Dental Federation (FDI)…
- Trial name
- NCT07518537
- Testing
- Thermoviscous bulk-fill composite restoration, Sonic-activated bulk-fill composite restoration, Flowable bulk-fill composite restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Deep Caries, Pulpitis Reversible
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
The goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults.
- Conditions
- Deep Caries, Pulpitis Reversible, Pulp Hyperemia
- Trial name
- NCT05816525
- Testing
- Partial removal of carious tissue, Final restoration
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Dental Caries
Comparative Evaluation of Hydrophilic and Hydrophobic Sealants in Partially Erupted First Molars
This randomized controlled clinical trial aims to evaluate and compare the retention, caries prevention, microleakage, and fluoride release of three types of pit and fissure sealants-hydrophilic, nanofilled hydrophobic, and…
- Trial name
- NCT07052526
- Testing
- Prevention, Prevention of caries, Prevention therapy
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries, Reversible Pulpitis
Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventional Syringe in Pediatric Patients
This randomized controlled trial is conducted on pediatric dental patients to compare the effectiveness of local anesthesia administered using a dental anesthesia injector device versus the traditional syringe method.
- Trial name
- NCT07101068
- Testing
- Dental Anesthesia Injector, conventional syringe
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Caries, Dental, Calcium Hypophosphite
Comparative Study of Caries-Preventive Effects: 2% Calcium Hypophosphite Toothpaste vs. Sodium Fluoride Toothpaste (1450ppm F)
The aim of the study is to compare the caries-preventive effect of the test and control toothpaste in order to proof the non-inferiority of the test toothpaste compared to the control.
- Conditions
- Caries, Dental, Calcium Hypophosphite, Fluoridation
- Trial name
- NCT07068204
- Testing
- 2% Calcium Hypophosphite Toothpaste, Sodium Fluoride Toothpaste (1450 ppm F)
- Where
- 2 sites in Poland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Dr. Joachim Enax
Reversible Pulpitis, Dental Caries
Effect of Hemostatic Agents on TheraCal PT Pulpotomy Success in Primary Molars
Dental caries in primary teeth can sometimes lead to inflammation of the dental pulp, the soft tissue inside the tooth. When the pulp remains capable of healing, pulpotomy may be performed to preserve the tooth until its natural…
- Conditions
- Reversible Pulpitis, Dental Caries, Primary Molar Pulpotomy, Dental Pulp Exposure
- Trial name
- CEHA-TP RCT (NCT07876934)
- Testing
- 2.5% Sodium Hypochlorite applied to pulpal tissue/stumps for 3 minutes to achieve hemostasis prior to TheraCal PT placement during primary molar pulpotomy and 15% Ferric Sulfate (Astringedent™ 15.5%)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Reem Mohamed Gaber
Remineralization Potential, Dentin Caries
Clinical Performance and Remineralization Potential of Self- Assembling Peptide P11-4 Containing Fluoride Versus Er, Cr: YSGG Laser Treatment and Micro Tensile Bond Strength of Giomer Restoration in Carious Lesions
This study will be performed in two parts, in vivo and in vitro to assess the effect of the remineralization potential of self-assembling peptide P11-4 containing Fluoride on caries-affected dentin compared to untreated…
- Trial name
- NCT07065305
- Testing
- Curodont Repair Fluoride Plus (Self-assembling peptide remineralization agent)P11-4 peptide, fluoride, mild acidic buffer (pH ~4.5) , Credentis AG, Switzerland, Beautifil II LS
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Caries Experience
Evaluation of Dental Caries Using Caries Assessment Spectrum and Treatment Need (CAST) Index, International Caries Detection and Assessment System (ICDAS) Index and World Health Organization (WHO) Index
This study goals is to compare the three indices in Egyptian children aged 4 to 6 years in caries detection and time needed for the assessments which will contribute to valuable data for pediatric oral health assessments both…
- Trial name
- CAST/ICDAS/WHO (NCT06858462)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Restoration, Permanent, Dental Restorations
Clinical Investigation Measuring the Long Term Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.
The aim of this present study is to collect additional data for the post-marketing follow-up of Biodentine™ XP and measure long-term (up to 10 years) performance and safety of the biomaterial in all its indications.
- Conditions
- Dental Restoration, Permanent, Dental Restorations, Endodontic Treatment
- Trial name
- BIOD XP (NCT06955429)
- Testing
- Dental restorative or endodontic treatment requiring Biodentine XP use
- Where
- 8 sites in Belgium, France
- Volunteers
- 275 people
- Sponsor
- Septodont
Dental Disorders Hard Tissues of Teeth, Dental Diseases
Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns
This investigation will be a randomized, prospective, longitudinal clinical trial to study the clinical performance of a new monolithic, zirconia material with shade, translucency and material graduation for chairside CAD/CAM…
- Trial name
- NCT06173167
- Testing
- Crowns self-adhesively luted, Crowns conventionally cemented
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG