Clinical trials: Decision Support System, active
Cirrhosis, Decision Support Systems, Clinical
CirrhosisRx CDS System
The aim of the study is to compare the effect of CirrhosisRx, a novel clinical decision support (CDS) system for inpatient cirrhosis care, versus "usual care" on adherence to national quality measures and clinical outcomes for…
- Trial name
- NCT05967273
- Testing
- CirrhosisRx CDS
- Where
- United States
- Volunteers
- 2,106 people
- Sponsor
- University of California, San Francisco
Glioma, Glioma (Diagnosis)
AI-driven Processing and Analysis of Glioma Imaging Data
GLIOMAID is a scientific research project focused on improving how brain tumors, specifically gliomas, are diagnosed and managed. It uses Artificial Intelligence (AI) to analyze MRI brain scans and patient data.
- Trial name
- GLIOMAID (NCT07703761)
- Testing
- AI-driven analysis of brain MRI data for early, non-invasive detection, segmentation, and histological characterization of gliomas using retrospective clinical and imaging records.
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Università degli Studi di Trento
Heart Failure
Decision Support System for Diagnosis and Progression of Heart Failure
Heart failure (HF) is a complex clinical syndrome associated with impaired heart function, poor quality of life for patients and high healthcare costs.
- Trial name
- STRATIFYHF (NCT06377319)
- Testing
- Cardiac Output Response to Stress (CORS) test
- Volunteers
- 1,600 people
- Sponsor
- Coventry University
Pain, Chronic, Chronic Pain, Widespread
Person-Centred AI Support in Interdisciplinary Rehabilitation for Chronic Pain
This cluster randomized controlled trial evaluates whether a person-centred, AI-supported Clinical Decision Support System (CDSS) can improve outcomes and cost-effectiveness in interdisciplinary rehabilitation for people with…
- Conditions
- Pain, Chronic, Chronic Pain, Widespread, Pain Management
- Trial name
- pAIn (NCT07081737)
- Testing
- Interdisciplinary treatment (IDT) + Clinical Decision Support System (CDSS), Interdisciplinary treatment (IDT)
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Bjorn Ang
Severe Sepsis, Severe Sepsis Without Septic Shock
Sepsis Clinical Decision Support [CDS] Master Enrollment Study Protocol
This protocol will collect real-world data retrospectively from the electronic health record (EHR) as data obtained from the delivery of routine medical care to develop a machine learning (ML)-based Clinical Decision Support…
- Trial name
- NCT05304728
- Where
- 10 sites in United States
- Volunteers
- 40,000 people
- Sponsor
- Beckman Coulter, Inc.
Diagnostic Decision Making
Integrating AI Predictions With Clinician Expertise
Optimizing the interaction between the human and the machine is a major topic when deploying artificial intelligence (AI) at the bedside.
- Trial name
- NCT07457840
- Testing
- Bayesian-Updated Post-Test Probability, Standard AI Predicted Probability, Uncertainty Quantification (95% Confidence Interval)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV Infections, Preexposure Prophylaxis (PrEP)
Clinical Decision Support for PrEP
Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the federal initiative to end the HIV epidemic. However, healthcare providers lack tools to identify patients who are at increased risk for HIV infection and…
- Trial name
- PrEDICT (NCT05245201)
- Testing
- Standard of care, Clinical decision support for PrEP
- Where
- 3 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Acute Cardiovascular Disease, ST-segment Elevation Myocardial Infarction (STEMI)
MAchine Learning to Boost the Early Diagnosis of Acute Cardiovascular Conditions
The research project aims to develop clinical decision support tools integrating established diagnostic variables and machine learning (ML) models for rapid diagnosis of acute life-threatening cardiovascular conditions in…
- Conditions
- Acute Cardiovascular Disease, ST-segment Elevation Myocardial Infarction (STEMI), NSTEMI - Non-ST Segment Elevation MI
- Trial name
- MALBEC (NCT06927791)
- Testing
- Machine learning based development of a diagnostic tool for acute cardiovascular disease
- Where
- Switzerland
- Volunteers
- 200,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Atrial Fibrillation, Stroke
Computerized Decision Support to Prevent Stroke in Atrial Fibrillation
Atrial fibrillation (AF) is the most preventable cause of stroke. However, despite widely available risk stratification tools, numerous options for oral anticoagulation, and evidence-based practice guidelines, anticoagulation for…
- Trial name
- AF-ALERT3 (NCT06355986)
- Testing
- Alert-based computerized decision support
- Where
- 2 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Brigham and Women's Hospital
Unresectable Hepatocellular Carcinoma
AI-Guided First-Line Immunotherapy Selection in Unresectable Hepatocellular Carcinoma
This pragmatic, multicenter, cluster-randomized trial will evaluate whether a locked artificial intelligence (AI) clinical decision-support system can improve outcomes by helping multidisciplinary teams select first-line immune…
- Trial name
- HCC-AI-SELECT (NCT07729618)
- Testing
- AI-Assisted Clinical Decision Support Strategy, Usual-Care Multidisciplinary Treatment-Selection Strategy
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Tongji Hospital
Postpartum Depression
Implementation of a Clinical Decision Support Tool for Postpartum Depression
This study will evaluate the use of an automated process in the electronic health record (EHR) that will help providers to detect patients at risk of developing postpartum depression (PPD).
- Trial name
- CDS (NCT06818734)
- Testing
- Clinical Decision Support Tool
- Where
- 4 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pediatric ALL, Sepsis
Evaluation of Pediatric eCART Implementation
This is a study comparing 3 years of retrospective data (pre-implementation) to 2 years of prospective data after the implementation of a pediatric version of Electronic Cardiac Arrest Risk Triage (pediatric eCART), a clinical…
- Trial name
- NCT06771830
- Testing
- Pediatric eCART
- Where
- United States
- Volunteers
- 30,000 people
- Sponsor
- University of Wisconsin, Madison
Anxiety, Traumatic Stress
Personalizing Mental Health Treatment for Youth and Families
Incompatibility between evidence-based treatments (EBTs) and the cultural values, practices, and minoritized experiences of Latine youth and families contributes to racial-ethnic disparities in mental health treatment engagement…
- Conditions
- Anxiety, Traumatic Stress, Disruptive Behavior, Depression
- Trial name
- NCT07425366
- Testing
- Culturally Responsive Assessment, Formulation, and Treatment Tool (CRAFTT), Cultural Formulation Interview, Modular Approach to Therapy for Children
- Volunteers
- 64 people
- Sponsor
- University of Oregon
Complicated Diverticulitis, Acute Diverticulitis
AIDE: Decision Support for Anastomosis or Colostomy in Emergency Surgery for Complicated Acute Diverticulitis
The AIDE/OBS study is a multicenter, observational, non-interventional study designed to collect standardized clinical, radiological, intraoperative visual, and surgical reasoning data from adult patients undergoing non-elective…
- Conditions
- Complicated Diverticulitis, Acute Diverticulitis, Peritonitis, Perforated Diverticulitis
- Trial name
- AIDE/OBS/2025 (NCT07651072)
- Testing
- Primary anastomosis, Hartmann's procedure
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS San Raffaele Roma
Mechanical Ventilation
Titration of Oxygen Levels During Mechanical Ventilation With Electronic Alerts
Fractional oxygen during mechanical ventilation, is a life sustaining therapy in the intensive care unit , used for about a million patients annually.
- Trial name
- TOOLs (NCT04481581)
- Testing
- Electronic Alerts
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Acute Cystitis
Dispensing of Antibiotics in Pharmacies for Cystitis According to a Delegation Protocol, Impact of a Decision Support Tool. PHARIBO: PHarmacy and Resolved Antibiotherapy for Urinary Tract Infections
The purpose of this trial is to demonstrate that when treating acute cystitis without risk of complication, pharmacists may use share Decision Making tool to help patients to better understand the stakes of taking antibiotics and…
- Trial name
- PHARIBO (NCT07118748)
- Testing
- Share making decision tool, Delegation protocol
- Where
- 26 sites in France
- Volunteers
- 506 people
- Sponsor
- University Hospital, Bordeaux
Arterial Hypertension, Cardiovascular Diseases
Telemedical Algorithm-Supported Care for Hypertension
Hypertension is a major global health issue, affecting around 9 million people in Poland. While some studies indicate that telemonitoring benefits patients with hypertension, there is a lack of research evaluating tools that…
- Trial name
- SOT-ART-HT (NCT06722625)
- Testing
- Evaluation of a blood pressure monitoring system with an integrated algorithm that supports the doctor's decision-making process
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Poznan University of Medical Sciences
Breast Cancer, Ovarian Cancer
EHR Intervention to Increase HBOC Genetic Testing
The purpose of this research study is to test how well a new approach - using tools built into the electronic health record (EHR)- can help increase genetic testing for hereditary breast and ovarian cancer (HBOC) in women who…
- Conditions
- Breast Cancer, Ovarian Cancer, Hereditary Cancer Syndrome
- Trial name
- ELISABETH (NCT07876349)
- Testing
- ELISABETH Evidence-Informed Program (EIP)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Columbia University
Atrial Fibrillation
Optimizing Stroke Prophylaxis of Acute Atrial Fibrillation With an Electronic Clinical Decision Support Tool
Atrial fibrillation (AF) is the most common arrhythmia in the world, with significant morbidity and mortality. With appropriate oral anticoagulation, the risk of stroke due to atrial fibrillation decreases by 64%.
- Trial name
- AF SWCRT-CDS (NCT05341986)
- Testing
- Clinical Decision Support (CDS) tool
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Oregon Health and Science University
Pneumonia - Bacterial, Urinary Tract Infection Bacterial
Clinical Impact of a Machine Learning Decision Support System for Empirical Antibiotic Therapy
The goal of this quasi-experimental study is to analyze if a Machine Learning Clinical Decision Support System can improve the empirical antibiotic treatment in patients with pneumonia, urinary tract infection and / or sepsis.
- Conditions
- Pneumonia - Bacterial, Urinary Tract Infection Bacterial, Bloodstream Infection
- Trial name
- NCT07762378
- Testing
- Machine Learning Decision Support System
- Volunteers
- 486 people
- Sponsor
- Instituto de Investigación Sanitaria Gregorio Marañón