Clinical trials: Decision Support Systems, Clinical, open to volunteers
Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus (T1DM)
Pediatric Insulin Plan Calculator for T1DM Management
This is a multi-centre, prospective, randomized, open-label controlled trial designed to evaluate the effectiveness of a flexible digital insulin dose calculator in children under 12 years of age with Type 1 Diabetes Mellitus…
- Conditions
- Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus (T1DM), T1DM, T1DM - Type 1 Diabetes Mellitus
- Trial name
- FLEXI-T1D (NCT07427134)
- Testing
- Flexible Digital Insulin Dose Calculator
- Where
- 2 sites in Iraq, Pakistan
- Volunteers
- 440 people
- Sponsor
- Sultan Qaboos University
Human Immunodeficiency Virus, Treatment Adherence
Data Science and Qualitative Research for Decision Support in the HIV Care Cascade
The goal of this study is to determine whether clinical prediction algorithms derived using statistical machine learning methods can be used to improve patient outcomes in large HIV care programs in sub-Saharan Africa and…
- Conditions
- Human Immunodeficiency Virus, Treatment Adherence, Treatment Compliance, Patient No Show
- Trial name
- CASCADE (NCT06604663)
- Testing
- Activation of the CDSS system
- Where
- Kenya
- Volunteers
- 80,000 people
- Sponsor
- Brown University
Acute Kidney Injury, Intensive Care
The Cost-effectiveness of Artificial Intelligence Acute Kidney Injury Prediction Auxiliary Software (Acura AKI)
"Huede" AI Aided AKI Prediction Software, Acura AKI, uses machine learning algorithms to predict the risk of AKI within the next 24 hours and provide a ranking of feature importance.
- Conditions
- Acute Kidney Injury, Intensive Care, Renal Replacement Therapy
- Trial name
- NCT06685367
- Testing
- Acura AKI
- Where
- Taiwan
- Volunteers
- 3,600 people
- Sponsor
- Huede Healthtech Co., Ltd.
Children With Medical Complexity (CMC), Multiple Chronic Conditions
Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis
The goal of this pilot hybrid type I efficacy/implementation trial is to assess a newly developed decision support tool patients, parents, and providers to use during surgical treatment decision making for neuromuscular scoliosis…
- Conditions
- Children With Medical Complexity (CMC), Multiple Chronic Conditions, Neuromuscular Scoliosis, Shared Decision Making
- Trial name
- NCT07167927
- Testing
- Decision support tool
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Utah
Cirrhosis, Decision Support Systems, Clinical
CirrhosisRx CDS System
The aim of the study is to compare the effect of CirrhosisRx, a novel clinical decision support (CDS) system for inpatient cirrhosis care, versus "usual care" on adherence to national quality measures and clinical outcomes for…
- Trial name
- NCT05967273
- Testing
- CirrhosisRx CDS
- Where
- United States
- Volunteers
- 2,106 people
- Sponsor
- University of California, San Francisco
Cardiogenic Shock, Cardiogenic Shock Acute
Prospective Validation of the STOPSHOCK Score - Artificial Intelligence Based Predictive Scoring System to Identify the Risk of Developing Cardiogenic Shock (CS) in Patients Suffering From Acute Coronary Syndrome (ACS)
Cardiogenic shock (CS) is a severe complication of acute coronary syndrome (ACS) with mortality approaching 50% despite the use of percutaneous mechanical circulatory support devices (pMCS).
- Conditions
- Cardiogenic Shock, Cardiogenic Shock Acute, Cardiogenic Shock Post Myocardial Infarction, Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
- Trial name
- STOPSCHOCK (NCT07090382)
- Where
- Slovakia
- Volunteers
- 1,046 people
- Sponsor
- Premedix Academy
Hepatocellular Carcinoma (HCC)
AI-Guided Surveillance and Curative Salvage of Recurrence After Hepatocellular Carcinoma Resection or Ablation
Hepatocellular carcinoma, the most common type of primary liver cancer, can recur after liver resection or thermal ablation performed with curative intent.
- Trial name
- HCC-AI-RECLAIM (NCT07732504)
- Testing
- Artificial Intelligence-Guided Risk-Adapted Surveillance, Fixed-Interval Surveillance
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Tongji Hospital
Prostate Cancer, Prostate Cancer Screening Decision
Clinical Utility of ClarityDX Prostate
ClarityDX Prostate builds upon the utility of total and free PSA as well as simple clinical features in a decision support model to determine a patient's risk of having clinically significant prostate cancer.
- Conditions
- Prostate Cancer, Prostate Cancer Screening Decision, Prostate Cancer Screening
- Trial name
- NCT06678828
- Testing
- ClarityDX Prostate, ClarityDX Prostate, blinded
- Where
- 5 sites in Canada
- Volunteers
- 1,450 people
- Sponsor
- Nanostics
Rheumatoid Arthritis
GenAI-Assisted Rheumatoid Arthritis Bone Erosion Risk Assessment and DMARD Selection
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive joint damage and bone erosion. Accurate assessment of RA bone erosion risk (RABER) and appropriate disease-modifying antirheumatic drug…
- Trial name
- RABER (NCT07914907)
- Testing
- GenAI-Assisted Clinical Decision Support for RABER Assessment and DMARD Selection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Major Adverse Cardiovascular Events, Cardiovascular Testing and Consultation Intensity
How Institutional Guidelines for Urgent Inpatient Surgeries Affect Intensity of Perioperative Cardiovascular Testing
This study will evaluate the impact of implementing an educational clinical decision support (CDS) tool designed to guide perioperative cardiovascular evaluation for adults undergoing urgent inpatient surgery.
- Trial name
- NCT07692503
- Volunteers
- 3,000 people
- Sponsor
- Johns Hopkins University
Wounds, Wounds and Injuries
Pilot Trial for WounDx™ Clinical Decision Support Tool
The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital.
- Conditions
- Wounds, Wounds and Injuries, Extremity Injury, Traumatic Wounds and Injuries
- Trial name
- NCT06921707
- Testing
- Clinical Decision Support Tool, Standard of Care (SOC)
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Insomnia Disorder, Mild Traumatic Brain Injury
Sleep MAPP in the Polytrauma/TBI System of Care
This pilot implementation trial will evaluate the Sleep Disorder Management Assistance for Providers and Patients (Sleep MAPP) Care Pathway in one Veterans Health Administration Polytrauma/TBI System of Care clinic.
- Trial name
- Sleep MAPP (NCT07886398)
- Testing
- Sleep MAPP Care Pathway
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- VA Office of Research and Development
Infectious Diseases
Prescription Support System for Antimicrobial Use in Belgian Primary Care
Inappropriate antibiotic prescribing in primary care remains an important contributor to antimicrobial resistance. Despite the availability of evidence-based clinical guidelines, antibiotics are still frequently prescribed for…
- Trial name
- PaSSo (NCT07347015)
- Testing
- Prescription Support System (PSS)
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- KU Leuven
Oncologic Surgery, Gastrointestinal Cancers
Clinical Evaluation of AI Decision Support for Early Rehabilitation After Surgery
After gastrointestinal or oncology surgery, it can be difficult to determine when a patient is ready to safely begin early rehabilitation or move toward discharge.
- Trial name
- DESIRE (NCT07406269)
- Testing
- DESIRE: AI-Based Clinical Decision Support for Postoperative Rehabilitation Planning
- Where
- Netherlands
- Volunteers
- 103 people
- Sponsor
- Erasmus Medical Center
Glioma, Glioma (Diagnosis)
AI-driven Processing and Analysis of Glioma Imaging Data
GLIOMAID is a scientific research project focused on improving how brain tumors, specifically gliomas, are diagnosed and managed. It uses Artificial Intelligence (AI) to analyze MRI brain scans and patient data.
- Trial name
- GLIOMAID (NCT07703761)
- Testing
- AI-driven analysis of brain MRI data for early, non-invasive detection, segmentation, and histological characterization of gliomas using retrospective clinical and imaging records.
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Università degli Studi di Trento
Diagnostic Decision Making
Integrating AI Predictions With Clinician Expertise
Optimizing the interaction between the human and the machine is a major topic when deploying artificial intelligence (AI) at the bedside.
- Trial name
- NCT07457840
- Testing
- Bayesian-Updated Post-Test Probability, Standard AI Predicted Probability, Uncertainty Quantification (95% Confidence Interval)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Organ Donation After Circulatory Death, Organ Donation
Improving Deceased Organ Donation and Transplantation Using the Donation Advisor Clinical Decision Support Tool
Every year, thousands of Canadians receive life-saving, cost-effective organ transplants, while thousands more still wait or die because not enough organs are available.
- Conditions
- Organ Donation After Circulatory Death, Organ Donation, Clinical Decision Support Tool
- Trial name
- DART (NCT07903428)
- Testing
- Donation Advisor clinical decision-support tool
- Volunteers
- 10 people
- Sponsor
- OBS Medical Ltd
Genetic Disease, Neurogenetic Disorders
Pediatric Neurogenetic Diagnosis Support Platform
This study evaluates a diagnostic support platform, DIAGEN-IA, designed to identify pediatric neurological diseases with a genetic basis.
- Trial name
- DIAGEN-IA (NCT06725901)
- Testing
- Web-Based Application
- Where
- Chile
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Atherosclerotic Cardiovascular Disease
EHR Nudges: Optimizing a Clinical Decision Support System for Evidence-Based Statin Medication Prescribing to Reduce the Risk of Cardiovascular Disease
The overall objective of this proposal is to develop and optimize a CDSS, including several nudges, to increase guideline-concordant statin prescribing for CVD risk (Nudge-CVD-CDSS).
- Trial name
- NCT07914777
- Testing
- EHR Nudge
- Where
- United States
- Volunteers
- 7,501 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Trauma, Injury
Clinical Evaluation of an AI Risk Prediction System (AI-TRiPS)
The goal of this clinical study is to evaluate a software device and its impact on clinician behaviour during the initial management of trauma patients in a real-world clinical setting.
- Conditions
- Trauma, Injury, Decision Support Systems, Clinical
- Trial name
- AI-TRiPS (NCT07634185)
- Testing
- AI-TRiPS Device
- Volunteers
- 1,200 people
- Sponsor
- Queen Mary University of London