Clinical trials: Deep Dental Caries
DME, Dental Caries
The Effect of Bulk Filling Flowable Composite on Caries Recurrence in Deep Marginal Elevation: A Randomized Clinical Trial
Deep marginal elevation usinge a bioactive dental material in deep subgingival Class II restorations, S-PRG filler-containing materials offer significant benefits due to their bioactive properties, Their ability to release…
- Conditions
- DME, Dental Caries, Dental, Deep Margin Elevation
- Trial name
- NCT06900868
- Testing
- Assigned Interventions
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Deep Caries, Indirect Pulp Capping
Pulp Capping in Primary Molars Using TheraCal (LC)
A randomized clinical trial that aims to evaluate clinical and radiographic success rates of indirect pulp capping and direct pulp capping in primary molars with reversible pulpitis using a light-cured tri-calcium silicate base…
- Conditions
- Deep Caries, Indirect Pulp Capping, Direct Pulp Capping, Reversible Pulpitis
- Trial name
- NCT05167123
- Testing
- Light cured tri-calcium silicate base material
- Where
- 3 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Caries, Reversible Pulpitis
Management of Deep Carious Lesions in Adults
Dental caries is one of the most prevalent non-communicable disease. However, despite its prevalence there is no consensus on how much caries to remove prior to placing a restoration to achieve optimal outcomes.
- Trial name
- NCT05144711
- Testing
- Selective caries excavation, Non selective caries excavation
- Where
- Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Caries, Dental Diseases
Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars
This research study delves into the effectiveness of bioactive and non-bioactive restorative systems in deep carious permanent molars treated with selective caries removal.
- Conditions
- Dental Caries, Dental Diseases, Deep Caries, Tooth Diseases
- Trial name
- NCT06348953
- Testing
- selective caries removal and conventional non-bioactive restorative system, selective caries removal and bioactive restorative system
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpal Inflammation, Dental Caries
Effect of Different Heating Protocols of Resin Composites on Pulp Condition (Randomized Controlled Trial)
This randomized controlled clinical trial evaluates the effect of different resin composite preheating protocols on pulpal inflammation and postoperative pain.
- Conditions
- Pulpal Inflammation, Dental Caries, Postoperative Pain
- Trial name
- NCT07720999
- Testing
- Arm 1 only "VisCalor Thermoviscous Bulk-Fill Composite", Tetric EvoCeram Conventional Nanohybrid Composite (Preheated 55°C), Tetric EvoCeram Conventional Nanohybrid Composite (Room Temperature)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Extremely Deep Caries, Pulpitis
Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries
Recent clinical trials comparing pulpotomy versus root canal treatment (RCT) have shown promising outcomes; however, the current evidence lacks generalisability to general practitioners.
- Trial name
- NCT07242742
- Testing
- Full Pulpotomy, root canal treatment and intracanal medicament
- Where
- Singapore
- Volunteers
- 93 people
- Sponsor
- National University Hospital, Singapore
Indirect Pulp Cap
A Study Comparing Eggshell Based and Gold Standard Materials to Heal Deep Tooth Damage in Adult Molars
This clinical trial will evaluate the effectiveness of eggshell-derived calcium hydroxyapatite compared to calcium hydroxide as indirect pulp capping agent in permanent teeth.
- Trial name
- NCT07183514
- Testing
- eggshell-derived calcium hydroxyapatite, Calcium hydroxide
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- University of Health Sciences Lahore
Caries,Dental, Crown of Tooth With Poor Contour
Clinical and Radiographical Evaluation of CAD-CAM Crowns With and Without Deep Margin Elevation
Deep margin elevation (DME) is a non-invasive restorative technique to relocate the deep cervical margin to a supragingival position using resin composite.
- Conditions
- Caries,Dental, Crown of Tooth With Poor Contour, Broken Teeth, Survival, Prosthesis
- Trial name
- NCT06114030
- Testing
- Deep margin elevation with composite resin and Lithium disilicate glass-ceramic crowns
- Where
- United Arab Emirates
- Volunteers
- 560 people
- Sponsor
- University of Sharjah
Dental Caries
Selective or Stepwise Removal of Deep Caries
Background: For treating deep caries lesions, selective or stepwise, i. e. one- and two-step incomplete excavation seems advantageous compared with complete caries removal.
- Trial name
- NCT02232828
- Testing
- Selective removal, Stepwise removal
- Where
- 4 sites in Germany
- Volunteers
- 300 people
- Sponsor
- Charite University, Berlin, Germany
Dental Caries
A Clinical Study of KH001 for Pulp Preservation and Safety in Deep Dentin Caries
The Purpose of this Study is to Evaluate Pulp Preservation and Safety of KH001 in the Administration of Deep Dentin Caries.
- Trial name
- NCT07751016
- Testing
- KH001
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Dental Hospital
Deep Caries, Carious Exposure of Pulp
Outcome of Selective & Nonselective Caries Removal in Permanent Teeth
Patients presenting with deep decay within permanent teeth presents a common clinical challenge to dentists. The aim of this trial is to compare the success rate of the non-selective caries removal (NSCR) and selective caries…
- Trial name
- RCT-SNCR (NCT06378814)
- Testing
- Selective Caries Removal (No Pulp Exposure), Non-Selective Caries Removal (No Pulp exposure), Partial Pulpotomy (Pulp Exposed)
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- King's College London
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Deep Carious Lesions, Caries Class I
A Comparative Study of Different Traditional and Bioactive Indirect Pulp Capping Materials
The protection of the dentin-pulp complex consists of the application of one or more layers of specific material between the restorative material and dental tissue to avoid additional challenge to the pulp tissue caused by…
- Conditions
- Deep Carious Lesions, Caries Class I, Caries Class II
- Trial name
- NCT06707311
- Testing
- patients received calcium hydroxide with glass ionomer restorative material, patients received TheraCal LC with glass ionomer restorative material, patients received bioactive bonding with glass ionomer restorative material
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Pulp Exposure, Dental, Deep Dental Caries
Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study
The effect of selective caries cleaning and total caries cleaning on pulp health and post operative pain in teeth with deep caries will be investigated.
- Trial name
- NCT07041905
- Testing
- Total Caries Removal, Selective Caries Removal
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Cukurova University
Patients With Deep Carious Lesions
Comparative Study Between Biodentine and Mineral Trioxide Aggregate in Direct Pulp Capping
Comparative study between Biodentine and MTA in direct pulp capping of deeply carious teeth.
- Trial name
- NCT02803528
- Testing
- Biodentine, MTA
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Ozone, Caries
Effectiveness of the Ozone Application in Two-Visit Indirect Pulp Therapy of Permanent Molars With Deep Carious Lesion
The aim of this study was to evaluate the clinical and microbiological effectiveness of the ozone application in two-visit indirect pulp therapy.
- Trial name
- ozone (NCT03693066)
- Testing
- Ozone, chlorhexidine digluconate, Control
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Artificial Intelligence, Education
Impact of Training Dental Students for an AI-Based Platform
The emergence of artificial intelligence (AI) and specifically deep learning (DL) have shown great potentials in finding radiographic features and treatment planning in the field of cariology and endodontics .
- Trial name
- NCT05912361
- Testing
- receiving a one hour theoretical and hands on training session before using an AI-based platform
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Deep Caries
Evaluation of the Remineralizing Effect of Aloe Vera Versus Diode Laser for Management of Deep Carious Lesions.
The present study will be performed to evaluate: The remineralizing effect of Aloe Vera versus Diode laser on deep carious dentin after selective caries removal.
- Trial name
- NCT05327049
- Testing
- no intervention, diode laser, Aloe Vera
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Caries, Dental
Effect of Pulpotomy Using TheraCal Versus MTA on Survival Rate of Cariously-Exposed Vital Permanent Molars
Objective: To assess which is the most efficient pulpotomy medicament on tooth survival in patients with a cariously-exposed vital young permanent molar regarding: absence of postoperative pain, sinus or swelling, internal/…
- Trial name
- NCT03119779
- Testing
- MTA-Anglus, TheraCal
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University