Clinical trials: Deep Infiltrating Endometriosis
Deep Infiltrating Endometriosis
Impact of Deep Endometriosis Surgery on Bladder Function
It has been demonstrated that ligaments, both cardinal and uterosacral contain a considerable amount of autonomic nerve tissues.
- Trial name
- NCT02238678
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Endometriosis
Evaluation of New Biomarkers in Stage 3 and 4 Endometriosis
The diagnostic value of Annexin V, sVCAM-1, sICAM-1, vascular endothelial growth factor and Proinflammatory cytokines (TNF-a and interleukin-6) in ovarian endometriosis and deep infiltrating endometriosis, their levels in…
- Trial name
- NCT05312528
- Testing
- endometriosis surgery, other benign condition surgeries
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Indocyanine Green (ICG), Robotic Surgical Procedure
Assessing the Efficacy of Indocyanine Green for Ureter Identification During Robot-Assisted Surgery in Advanced-Stage Endometriosis
The goal of this side-randomized, self-controlled trial, 1-site study is to explore the efficacy of Indocyanine Green Fluorescence (ICG) for Intraoperative Ureter Identification During Robot-Assisted Single-Site Surgery in…
- Conditions
- Indocyanine Green (ICG), Robotic Surgical Procedure, Deep Infiltrating Endometriosis (DIE), Endometriosis Pelvic
- Trial name
- NCT07144904
- Testing
- Indocyanine Green (ICG)-Assisted Ureteral Identification, Standard Ureteral Identification without ICG
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Deep Infiltrating Endometriosis (DIE), Transrectal Ultrasound
Evaluation of Rectal Infiltration Depth and Length in Bowel Involvement of Deep Infiltrative Endometriosis (DIE) Using Intraoperative Transrectal Ultrasound (TRUS)
we aim to evaluate the success of intraoperative transrectal ultrasound in measuring the depth and extent of bowel involvement in patients preoperatively diagnosed with intestinal endometriosis using transvaginal ultrasound and…
- Conditions
- Deep Infiltrating Endometriosis (DIE), Transrectal Ultrasound, Bowel Endometriosis, Bowel Resection
- Trial name
- DIE IO TRUS (NCT06776536)
- Testing
- Transrectal ultrasound of the bowel endometriosis during operation
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Deep Infiltrating Endometriosis (DIE)
A Study to Describe the Efficacy of Diphereline Following Conservative Surgery in Deep Infiltrating Endometriosis (DIE) Patients Over a Period of 24 Months
The purpose of this study is to describe changes in the intensity of specific endometriosis symptoms from baseline pre-surgery to after surgery and subsequent continuous Diphereline (Triptorelin Acetate) treatment for up to 24…
- Trial name
- DIE-NIS (NCT01942369)
- Testing
- Triptorelin Acetate 3.75mg intramuscular injection
- Where
- 18 sites in China
- Volunteers
- 402 people
- Sponsor
- Ipsen
Endometriosis, Adhesion
New Cross Linked Hyaluronan Gel After Deep Infiltrating Endometriosis Surgery
Hyaluronan, a glycosaminoglycan found in connective tissues and extracellular matrix, has been postulated to reduce postoperative adhesions, because of its unconditioned biological functions at tissue repair but unfortunately it…
- Conditions
- Endometriosis, Adhesion, Quality of Life, Surgery
- Trial name
- HYALOENDOQoL (NCT04023383)
- Testing
- 40 cc HyaRegen NCH gel, 40 cc sterile saline solution
- Volunteers
- 60 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Endometriosis
Surgical Eradication of Deep Infiltrating Endometriosis of the Vagina
Multicentric retrospective study about the comparison of two different techniques of vaginal breach suturing after eradication surgery for deep infiltrating endometriosis and the surgical approaches (laparoscopic or vaginal) in…
- Trial name
- ENDO-VAG-r (NCT03744143)
- Testing
- longitudinal suture, transverse suture, Removal of vaginal endometriotic nodule
- Where
- 2 sites in Italy
- Volunteers
- 84 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Deep Infiltrating Endometriosis
Quality of Life and Fertility of Patient With Deep Surgical Endometriosis: a Prospective Cohort
Endometriosis is a common gynaecologic disease affecting 5 to 15% women of reproductive age and up to 40% of infertile women. It is characterized by the presence of active endometrial tissue outside the uterine cavity…
- Trial name
- ENDORAA (NCT03555903)
- Testing
- Endometriosis cohort
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Hospices Civils de Lyon
Endometriosis
Outcome After Multidisciplinary CO2 Laser Laparoscopic Excision of Deep Infiltrating Colorectal Endometriosis
Improved pain, sexuality and quality of life, high fertility and low complication and recurrence rates after multidisciplinary CO2 laser laparoscopic excision of deep infiltrating colorectal endometriosis.
- Trial name
- NCT00461838
- Testing
- multidisciplinary laparoscopy, Questionnaires
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University Hospital, Gasthuisberg
Deep Infiltrating Endometriosis With or Without Bowel Involvement
Intraoperative Ultrasound in Bowel Deep Endometriosis
This study investigates the use of intraoperative transvaginal (IOTVUS) and/or endorectal ultrasound (IOERUS) in the surgical treatment of bowel deep infiltrating endometriosis (DIE).
- Trial name
- NCT06876376
- Testing
- intraoperative ultrasound for the assessment of bowel deep infiltrating endometriosis
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacion Dexeus
Endometriosis
Improvement in Quality of Life and Pain Scores After Laparoscopic Management of Deep Infiltrating Endometriosis
This is a retrospective cohort study that evaluates the postoperative pain findings of a consecutive series of laparoscopic surgeries for deep infiltrating endometriosis (DIE).
- Trial name
- NCT04062916
- Testing
- BSGE pelvic pain questionnaire and VAS scores
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Acibadem Fulya Hastanesi
Endometriosis Related Pain, Quality of Life
Bowel ENDOmetriosis; Evaluation of Diagnostics and Quality of Life
Endometriosis on the bowel is a benign condition that can cause major complaints and severely affect the quality of life of women of fertile age.
- Conditions
- Endometriosis Related Pain, Quality of Life, Pain, Chronic, Bowel Dysfunction
- Trial name
- ENDO (NCT03779256)
- Testing
- 2D transvaginal ultrasound
- Where
- 3 sites in Australia, Austria and 1 more
- Volunteers
- 207 people
- Sponsor
- Oslo University Hospital
Pelvic Endometriosis, Endometriosis Outside Pelvis
Near-infrared Fluorescence Imaging as a Supportive Tool for Localisation of Deep Infiltrating Endometriosis During Laparoscopy
The aim of the study is to establish a new and more accurate method to visualize the peritoneal changes caused by endometriosis using Indocyanine Green mediated fluorescence imaging.
- Trial name
- NCT03332004
- Testing
- Indocyanine Green
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- Catholic University of the Sacred Heart
Pelvic Endometriosis, Endometriosis Outside Pelvis
Prospective Evaluation of Near-infrared Fluorescence Imaging Use as a Supportive Tool in Deep Infiltrating Endometriosis Surgery
The aim of the study is to establish a new and more accurate method to visualize the peritoneal changes caused by endometriosis using Indocyanine Green mediated fluorescence imaging.
- Trial name
- GRE-Endo-2 (NCT03935165)
- Testing
- Indocyanine Green
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Catholic University of the Sacred Heart
Endometriosis
Treatment by HIFU With Focal One® of Posterior Deep Infiltrating Endometriosis Lesions With Intestinal Involvement.
Deep invasive endometriosis (DIE) includes lesions of the rectosigmoid. Theses lesions are associated with painful symptoms that can alter quality of life.
- Trial name
- NCT03613298
- Testing
- HIFU (Focal One®)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- EDAP TMS S.A.
Deep Endometriosis, Surgery
Imaging Comparison for the Preoperative Planning and Diagnosis of DIE: a Multicenter Retrospective Study.
Several centers in Belgium use both transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for the preoperative diagnosis of deep infiltrating endometriosis (DIE), while other centers rely almost exclusively on TVS.
- Conditions
- Deep Endometriosis, Surgery, Transvaginal Ultrasound, MRI
- Trial name
- NCT06994091
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Ziekenhuis Oost-Limburg
Deep Endometriosis, Surgery
Surgical TReatment of Women With Deep ENDometriosis
TrEnd trial is aimed to collect data from consecutive patients undergoing segmental sigmoid colon/rectal resection for deep endometriosis.
- Trial name
- TrEnd (NCT06386276)
- Testing
- Colorectal bowel resection
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Casa di Cura Privata 'Malzoni - Villa dei Platani' S.P.A.
Endometriosis, Endometriosis, Rectum
Patient Reported Outcomes After Surgery for Rectal Endometriosis
To describe the difference in patient reported outcomes after conservative treatment in comparison to radical rectal surgery in patients with deep endometriosis infiltrating the rectum (up to 15cm from the anus with at least…
- Conditions
- Endometriosis, Endometriosis, Rectum, Endometriosis-related Pain, Endometriosis; Bowel
- Trial name
- PROCURE (NCT04204707)
- Testing
- PROMS
- Where
- 2 sites in Belgium, Hungary
- Volunteers
- 294 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometriosis, Deep Infiltrating Endometriosis
Prospective Trial of [18F]AlF-FAPI-74 for PET Imaging of Fibroblast Activation Protein in Patients With Endometriosis
The goal of this clinical trial is to learn whether [18F]AlF-FAPI-74 PET/CT can help detect endometriosis in adult women who are already scheduled for laparoscopy due to suspicion of deep infiltrating endometriosis or superficial…
- Conditions
- Endometriosis, Deep Infiltrating Endometriosis, Women, Superficial Peritoneal Endometriosis
- Trial name
- EM-FAPI (NCT07876648)
- Testing
- [18F]AlF-FAPI-74 PET/CT
- Where
- Belgium
- Volunteers
- 64 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven