Clinical trials: Deep Vein Thrombosis,
Atrial Fibrillation, Deep Vein Thrombosis
Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients
The purpose of this study is to determine whether pharmacogenetic guided dosing of warfarin is promising for the improvement of efficiency, therapeutic efficacy, and, especially, safety of warfarin therapy than a dosing regimen…
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism, Heart Valve Disease
- Trial name
- NCT01610141
- Testing
- Genotype-guided warfarin dosing, Non-genotype guided warfarin dosing
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
DVT, Osteoarthritis
Does Thinning the Blood During Surgery Prevent Blood Clots Following Total Knee Replacement Surgery
The goal of this study is to prevent blood clots from forming during surgery and a few days after total knee replacement surgery.
- Trial name
- NCT00253851
- Testing
- unfractionated heparin
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
Deep Venous Thrombosis
Outcome of Percutaneous Mechanical Thrombectomy to Treat Acute Deep Venous Thrombosis
The purpose of this study was to compare the efficacy of Percutaneous mechanical thrombectomy (PMT) followed by standard anticoagulant therapy, with anticoagulation therapy alone, for the treatment of acute proximal lower…
- Trial name
- NCT02959801
- Testing
- Percutaneous mechanical thrombectomy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Pulmonary Embolism, Thromboembolism
Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism)
This is a multicenter, randomized, double-blind, event-driven, superiority study for efficacy. Patients with confirmed symptomatic DVT (Deep Vein Thrombosis) or PE (Pulmonary embolism) who completed 6 or 12 months of treatment of…
- Conditions
- Pulmonary Embolism, Thromboembolism, Thrombosis, Venous Thrombosis
- Trial name
- EinsteinChoice (NCT02064439)
- Testing
- BAY 59-7939, ASA
- Where
- 266 sites in United States, Australia and 29 more
- Volunteers
- 3,365 people
- Sponsor
- Bayer
Venous Thromboembolism, Deep Venous Thrombosis
Education Bundle to Decrease Patient Refusal of VTE Prophylaxis
The investigators have recently developed a registry of missed doses of VTE prophylaxis that includes retrospective data on missed doses of VTE prophylaxis.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
- Trial name
- NCT02402881
- Testing
- Patient-centered education bundle
- Where
- United States
- Volunteers
- 19,652 people
- Sponsor
- Johns Hopkins University
Suspected Deep Vein Thrombosis
The Designer D-dimer Deep Vein Thrombosis Diagnosis (4D) Study
This is a cohort study that will assess a new diagnostic management strategy for suspected Deep Vein Thrombosis in outpatients.The new diagnostic strategy is designed to reduce the use of ultrasound testing on the day of…
- Trial name
- 4D (NCT02038530)
- Where
- 10 sites in Canada
- Volunteers
- 1,513 people
- Sponsor
- McMaster University
Deep Vein Thrombosis
Feasibility of an Early Initiated Physiotherapy Intervention Among Patients With Deep Vein Thrombosis.
The project will investigate the feasibility of a physiotherapy intervention for patients diagnosed with deep vein thrombosis for whom a physiotherapy intervention is not currently part of clinical practice in Denmark.
- Trial name
- NCT05761119
- Testing
- Physical activity
- Where
- 2 sites in Denmark
- Volunteers
- 24 people
- Sponsor
- Hvidovre University Hospital
Deep Vein Thrombosis, Venous Thromboembolism
Phase 1 Pediatric Pharmacokinetics/Pharmacodynamics (PK/PD) Study
This is the first evaluation of edoxaban in pediatric subjects. In this Phase 1 study, a single dose of edoxaban will be given to pediatric subjects who require anticoagulant therapy to see what the body does to the drug…
- Trial name
- NCT02303431
- Testing
- Edoxaban low dose, Edoxaban high dose
- Where
- 35 sites in United States, Canada and 7 more
- Volunteers
- 66 people
- Sponsor
- Daiichi Sankyo
Venous Thromboembolism, Deep Vein Thrombosis
Detecting the Impact of Statin Therapy On Lowering Risk of Venous Thrombo-Embolic Events (DISOLVE)
Patients with cancer have a high risk of developing venous blood clots or thromboembolism (VTE). In an effort to target patients at highest risk of VTE for thromboprophylaxis (protective treatment for blood clots), numerous…
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Neoplasms
- Trial name
- DISOLVE (NCT01524653)
- Testing
- Rosuvastatin
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Vermont
Postoperative Complications, Postoperative Nausea and Vomiting
Electrical Acupoint Stimulation for Postoperative Recovery
This study investigates electrical acupoint stimulation (EAS) administered in peri-operation for improving postoperative recovery in elder patients, who accept knee arthroplasty.
- Conditions
- Postoperative Complications, Postoperative Nausea and Vomiting, Postoperative Infection, Postoperative Delirium
- Trial name
- EAS (NCT03249701)
- Testing
- Transcutaneous Electrical Acupoint Stimulation, Electroacupuncture
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shandong University of Traditional Chinese Medicine
Venous Thrombosis
Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurological Intensive Care
The investigators aim to compare the complications between centrally and peripherally inserted central venous catheters in neurological intensive care unit patients.
- Trial name
- PICNIC (NCT01495429)
- Testing
- Central venous catheter
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Iddvt, Pulmonary Embolism (PE)
Ultrasound Assessment of Isolated Distal Deep Vein Thrombosis
Retrospective assessment of ultrasound and clinical characteristics of patients with IDDVT, development of a pulmonary embolism risk prediction model for thrombus, and provision of appropriate diagnostic and therapeutic…
- Trial name
- IDDVT (NCT06596941)
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Ruijin Hospital
Deep-Venous Thrombosis
Leiden Trial in Prevention of Post-Operative ThromboEmbolic Events
In neurosurgical patients, the risk for venous thromboembolic events (VTE) is high due to the relatively long duration of surgery, the high occurrence of prolonged immobilization of patients due to paresis of the legs or…
- Trial name
- TIPOTEE (NCT02987946)
- Testing
- IPD Device delivered by Converis, Fraxiparine
- Where
- Netherlands
- Volunteers
- 280 people
- Sponsor
- Leiden University Medical Center
Deep Vein Thrombosis, Malignancy
Efficacy of Apixaban in Malignancy With Deep Venous Thrombosis
The aim of study was to evaluate the efficacy and safety of Apixaban in patients with acute deep venous thrombosis and active malignancy compared with weight adjusted subcutaneous (LMWH).
- Trial name
- DVT (NCT04462003)
- Testing
- Apixaban, Enoxaparin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Deep Vein Thrombosis, Deep Venous Insufficiency
A Study of Modified Limb Braking and Early Bed Mobility Strategies After Femoral Venipuncture Intervention
The goal of this clinical trial is to compare in describe participant population health conditions. The main questions it aims to answer are: To obtain the limb movement and bed mobility limits after femoral venipuncture, in…
- Trial name
- NCT05900622
- Testing
- Reduced postoperative braking and bed rest time.Lower extremity on the puncture side with a 2-hour brake+Get out of bed after 4 hours, Significantly reduce postoperative braking and bed rest time.No braking of the lower limb on the side of the puncture+Get out of bed after 2 hours
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tong Zhu
Central Venous Catheter Thrombosis
Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical…
- Trial name
- PHOTO CAT (NCT06417541)
- Testing
- Diseased patients with an indwelling central venous catheter who is referred to autopsy, Living patients with an indwelling central venous catheter referred to a CT scan without iv contrast
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Thomas Kander
Deep-Vein Thrombosis
Treatment of Upper Extremity Deep-Vein Thrombosis
The purpose of this study is to document the long-term outcome or prognosis of patients diagnosed with upper extremity deep-vein thrombosis who are treated with Fragmin (dalteparin sodium injection) for three months.
- Trial name
- NCT00245856
- Testing
- Dalteparin sodium injection, Warfarin
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- University of Oklahoma
Vascular, DVT - Deep Vein Thrombosis
Outcomes of Iliac Vein Stenting With Dedicated Venous Stents in Treatment of Chronic Post-thrombotic Venous Ulcers
Outcomes of iliac vein stenting with dedicated venous stents in treatment of chronic post-thrombotic venous ulcers Deep vein thrombosis (DVT) affects 1 to 3 individuals per 1000 annually.
- Conditions
- Vascular, DVT - Deep Vein Thrombosis, Post Thrombotic Syndrome, Venous Ulcer of Leg
- Trial name
- NCT07762222
- Testing
- dedicated venous stenting, Dedicated venous stent / iliofemoral dedicated venous stenting
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Traumatic Brain Injury
PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST)
This is a phase III, multi-centre, double blind, randomized controlled trial of patients with traumatic brain injury (TBI).
- Trial name
- PROTEST (NCT03559114)
- Testing
- Dalteparin, Saline
- Where
- 12 sites in Canada
- Volunteers
- 1,100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Deep Vein Thrombosis Leg, DVT
ClotTriever Outcomes (CLOUT) Registry
Evaluate real world patient outcomes after treatment of acute, subacute, and chronic proximal lower extremity deep vein thrombosis (DVT) with the ClotTriever Thrombectomy System.
- Conditions
- Deep Vein Thrombosis Leg, DVT, Chronic DVT of Lower Extremity, Acute DVT of Lower Extremity
- Trial name
- CLOUT (NCT03575364)
- Testing
- ClotTriever
- Where
- 43 sites in United States
- Volunteers
- 499 people
- Sponsor
- Inari Medical