Clinical trials: Deep Vein Thrombosis,
Venous Thromboembolism, Deep Vein Thrombosis (DVT)
Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study).
Evaluation of heparin/edoxaban tosylate (DU176b) versus heparin/warfarin in preventing recurrence of blood clots in patients with acute symptomatic deep-vein blood clots in the legs and/or blood clots in the lungs.
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Thromboembolism
- Trial name
- NCT00986154
- Testing
- edoxaban tosylate(DU-176b), low molecular weight heparin/unfractionated heparin, warfarin
- Where
- 454 sites in United States, Argentina and 36 more
- Volunteers
- 8,292 people
- Sponsor
- Daiichi Sankyo
Pregnancy, Deep Vein Thrombosis
Left Rule, D-Dimer Measurement and Complete Ultrasonography to Rule Out Deep Vein Thrombosis During Pregnancy.
In pregnant women with suspected DVT, a sure diagnosis is mandatory. In non-pregnant patients, sequential diagnostic strategies based on 1) the assessment of clinical probability, 2) D-dimer measurement and 3) compression…
- Trial name
- NCT01708239
- Testing
- Left rule, D-dimer measurement and complete ultrasonography in pregnant women.
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Marc Righini
Deep Vein Thrombosis
Limited Compression Ultrasound by Emergency Physicians to Exclude Deep Vein Thrombosis
Deep vein thrombosis is a common condition seen in the Emergency Department. Standard of care for diagnosis of DVT includes a combination of a clinical pre-test probability rule known as Well's criteria, D-dimer blood testing…
- Trial name
- NCT01007045
- Where
- 2 sites in Canada
- Volunteers
- 227 people
- Sponsor
- Queen's University
Deep Vein Thrombosis
Resolution Enhancement by a Supplemental Obstruction Lessening Venoactive Drug for Eight Weeks in Deep Vein Thrombosis
The RESOLVE-DVT study is a randomized single-center pilot study to determine the effects of hydroxyethylrutoside (Venoruton) on aspects of deep vein thrombosis (DVT) resolution associated with post-thrombotic syndrome (PTS).
- Trial name
- Resolve-DVT (NCT04670432)
- Testing
- Hydroxyethylrutoside
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Maastricht University Medical Center
Anticoagulant-induced Bleeding, Dental Diseases
Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy
Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral…
- Trial name
- NOADB (NCT03124030)
- Testing
- simple dental extraction
- Where
- Italy
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Medical Patient, Thrombocytopenia
Thromboprophylaxis of Venous Thromboembolism in Acutely-ill Medical Inpatients With Thrombocytopenia
Fondaparinux is a parenteral anticoagulant drug approved for the prophylaxis of venous thromboembolism in high risk medical patients.
- Trial name
- FAITH (NCT01727401)
- Testing
- Fondaparinux
- Where
- Italy
- Volunteers
- 7 people
- Sponsor
- G. d'Annunzio University
Hip Arthroplasty, Total, Prevention of Venous Thromboembolism
ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty
Surgical hip replacement (total hip arthroplasty, THA) is associated with a high risk of venous thromboembolism, but the appropriate duration of postoperative medical thromboprophylaxis ("anticoagulation") remains highly…
- Trial name
- ENABLE-Hip (NCT06611319)
- Testing
- Prevention of Venous Thromboembolism
- Where
- 6 sites in Austria, Germany
- Volunteers
- 2,932 people
- Sponsor
- Prof. Stavros Konstantinides, MD
Deep Vein Thrombosis
Comparison Of Different Mechanical Thrombectomy Devices in Endovascular Treatment of Acute Iliofemoral Venous Thrombosis
A head-to-head comparison of two different types of percutaneous mechanical thrombectomy (PMT) - ClotTriever System versus aspiration thrombectomy (including rheolytic thrombectomy) - in patients with acute iliofemoral deep vein…
- Trial name
- NCT07622212
- Testing
- Percutaneous mechanical thrombectomy by ClotTriever System, Percutaneous mechanical thrombectomy by aspiration or rheolytic thrombectomy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- RenJi Hospital
Venous Thrombosis
Satisfaction/Quality of Life With Rivaroxaban in DVT (Deep Venous Thrombosis) Indication
National, multicenter, prospective, observational, non-interventional study. The objective is to determine if the switch from Vitamin K antagonists (VKA) to Xarelto in subjects treated with VKA with issues in deep venous…
- Trial name
- SATORI (NCT01805544)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- France
- Volunteers
- 113 people
- Sponsor
- Bayer
Deep Vein Thrombosis, Thromboses, Venous
Ongoing Registry of Treatment of Venous Thromboembolism
Ongoing registration of patients with venous thromboembolism treated by means of antithrombotic therapy, thrombolisys, open surgery, endovenous desobstruction and stenting.
- Conditions
- Deep Vein Thrombosis, Thromboses, Venous, Thrombosis Embolism, Postthrombotic Syndrome
- Trial name
- RRT VTE (NCT03881345)
- Testing
- Anticoagulants, Open surgery, Thrombolysis
- Where
- Russia
- Volunteers
- 5,000 people
- Sponsor
- Medalp Private Surgery Clinic
Pregnancy Related, Deep Vein Thrombosis
SAFELY RULING OUT DEEP VEIN THROMBOSIS IN PREGNANCY WITH THE LEFt SCORE AND TRIMESTER-ADJUSTED D-DIMER CUTOFFS (the PREG-DVT Study): A PROSPECTIVE COHORT STUDY.
Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism (PE), is a leading cause of maternal morbidity and mortality in high-income countries.1 DVT is suspected in pregnancy greater than 10 times…
- Conditions
- Pregnancy Related, Deep Vein Thrombosis, D-dimer, Diagnostic Strategy
- Trial name
- PREG-DVT (NCT07884981)
- Testing
- D-dimer
- Where
- Switzerland
- Volunteers
- 330 people
- Sponsor
- Marc Righini
Venous Thromboembolism, Pulmonary Embolus
Multicenter Registry for Comparative Effectiveness Analysis of Venous Thromboembolism in Trauma Patients
Venous thromboembolism (VTE) remains a leading cause of death in trauma patients. Based on the EAST Management Guidelines for the prevention of VTE in trauma patients, a number of research questions could be addressed by a…
- Conditions
- Venous Thromboembolism, Pulmonary Embolus, Deep Vein Thrombosis
- Trial name
- CLOTT (NCT01890044)
- Where
- United States
- Sponsor
- Scripps Health
Pulmonary Embolism, Deep Vein Thrombosis
Safety of Topical Tranexamic Acid in Total Joint Arthroplasty in High Risk Patients
To evaluate whether there is a difference in symptomatic thromboembolism events in the subset of patients with a history of, or risk factors for thromboembolic disease for topically applied tranexamic acid in total joint…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Stroke, Myocardial Infarction
- Trial name
- NCT02644473
- Testing
- Tranexamic Acid, Normal saline
- Sponsor
- Albert Einstein College of Medicine
Venous Thrombosis, End Stage Renal Failure With Renal Transplant
The Risk of Venous Clotting in Patients After Renal Transplant
Clots that develop in the deep veins of the legs or the lungs can result in pain, heart and lung disease and may lead to death if unrecognized or not treated.
- Conditions
- Venous Thrombosis, End Stage Renal Failure With Renal Transplant, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- REPORT (NCT01413464)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Post-thrombotic Syndrome, Deep Vein Thrombosis Leg
Mechanisms of Deep Vein Thrombosis (DVT) and Vein Wall Fibrosis
The goal of this study is to determine the safety and tolerability or efficacy of adjunctive treatments (including rosuvastatin 20 mg daily) in combination with standard anticoagulation therapy (Factor Xa inhibitors) in patients…
- Trial name
- NCT04833764
- Testing
- Rosuvastatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Khanh Nguyen
Venous Thrombosis (Disorder)
Patient Education Bundle vs. Nurses Feedback and Coaching to Prevent Missed Doses of VTE Prophylaxis
VTE associated harm is underappreciated among hospitalized patients and may be associated with missed doses of VTE prophylaxis medications.
- Trial name
- ENACT (NCT03367364)
- Testing
- Patient education bundle (PEB),, Nurse feedback and coaching (NFC)
- Where
- United States
- Volunteers
- 9,657 people
- Sponsor
- Johns Hopkins University
Deep Vein Thrombosis, Venous Thrombosis
Treatment of an Acute Deep Vein Thrombosis (DVT) With Either Rivaroxaban or Current Standard of Care Therapy
Following the findings of the clinical trials in drug development, this global non-interventional cohort field study will investigate rivaroxaban under clinical practice conditions in comparison with current standard of care for…
- Trial name
- XALIA (NCT01619007)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Standard of care
- Where
- 21 sites in Austria, Belgium and 19 more
- Volunteers
- 5,145 people
- Sponsor
- Bayer
Thrombosis, Prevention
Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users
Reload of high dose statin may have potential for preventing deep vein thrombosis (DVT) in patients on statin undergoing total knee replacement arthroplasty.
- Conditions
- Thrombosis, Prevention, Surgery
- Trial name
- Re-STOP DVT (NCT01063426)
- Testing
- High dose Atorvastatin+enoxaparin, Enoxaparin
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Hallym University Medical Center
Renal Insufficiency
Venous Thromboembolism in Renally Impaired Patients and Direct Oral Anticoagulants
In renally impaired patients with acute venous thromboembolism (VTE), standard-of-care (SOC) anticoagulation, i.e. heparins-vitamin K antagonists (VKA), at therapeutic dosage is associated with an increased risk of thromboembolic…
- Trial name
- VERDICT (NCT02664155)
- Testing
- Apixaban, Rivaroxaban, Heparin
- Where
- 31 sites in France
- Volunteers
- 203 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Deep Vein Thrombosis
A Multi-center Cohort Study for Conventional Ultrasound Image Set Collection to Create a Data Set for Research Purposes.
This study aims to collect and create a labelled ultrasound image data set containing ultrasound image series and video clips of patients that undergo routine ultrasound scans on lower limbs, because of suspected deep vein…
- Trial name
- ThrombUS_A (NCT06989255)
- Where
- 5 sites in France, Greece and 2 more
- Volunteers
- 3,000 people
- Sponsor
- ThrombUS+