Clinical trials: Deficiency, Vitamin D
Vitamin D Deficiency, Vitamin D Insufficiency
Solius UV Light Source in Improving Serum Levels of 25-hydroxyvitamin D
This is a feasibility interventional study seeking to determine the safety and efficacy of the Solius Photobiologic System in increasing the serum levels of 25(OH)D in a vitamin D deficient/insufficient adult population.
- Trial name
- NCT04865432
- Testing
- UVB treatment
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston University
Obesity, Vitamin D Deficiency
Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
As the use of bariatric surgery for treatment of extreme obesity adults continues to rise, clinicians must be aware of pre-existing nutritional deficiencies in overweight and obese patients.
- Trial name
- NCT01385098
- Testing
- Vitamin D3 and Calcium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Vadim Sherman, MD
Vitamin D Deficiency, Thoracic Surgery
Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level
Our research group has shown that almost all children with congenital heart disease (CHD) are vitamin D deficient following heart surgery.
- Conditions
- Vitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, Congenital
- Trial name
- HICCUPS 2 (NCT01838447)
- Testing
- Cholecalciferol
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Children's Hospital of Eastern Ontario
SAR, SARS Pneumonia
Efficacy of Vitamin D Treatment in Mortality Reduction Due to COVID-19.
HYPOTHESIS: The administration of vitamin D supplements to patients who have a positive diagnosis for SARS-Cov-2, acute pneumonia requiring hospital admission and vitamin D deficiency have a more favourable evolution than…
- Trial name
- NCT04621058
- Testing
- Vitamin D
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Bioaraba Health Research Institute
Otosclerosis of Middle Ear, Bone Density
Investigating the Relationship Between Temporal Bone CT, Bone Density, and Hearing Loss in Otosclerosis Patients
The goal of this observational case-control study is to evaluate the relationship between temporal bone computed tomography (CT) findings, bone mineral density (BMD), and audiological parameters in adults diagnosed with…
- Conditions
- Otosclerosis of Middle Ear, Bone Density, Vitamin D Deficiency
- Trial name
- NCT06830187
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- İbrahim Emir Yeşil
Nutritional Rickets
Role of Calcium And Vitamin D In Nutritional Rickets And It's Management
Rickets, a common nutritional disorder, is usually considered to be due to vitamin D deficiency. However, in the last few decades many studies have shown that in tropical countries, with abundance of sunshine, calcium deficiency…
- Trial name
- ROCAVINR (NCT01578434)
- Testing
- Vitamin D, Calcium Carbonate, Vitamin D and Calcium
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Lady Hardinge Medical College
Hypovitaminosis D
Vitamin D Supplementation in Younger Women
That on average it will require a vitamin D dose of 1700IU/day to increase the serum 25hydroxyvitamin D level from 20 to 30ng/ml in young Caucasian women and a dose of 1860 to 2480 IU/day in African American
- Trial name
- VITADAS (NCT00662844)
- Testing
- vitamin D3
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Creighton University
Chronic Kidney Disease-Mineral and Bone Disorder
Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients
The goal of this observational study or clinical trial is to learn about the effect of neutrophil gelatinase-associated lipocalin (NGAL) on vascular calcification in maintenance hemodialysis patients with secondary…
- Trial name
- NGAL (NCT05720273)
- Testing
- palicalcitol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiaoyan Jia
Hypertension
Vitamin D Augmentation of Tekturna (Aliskiren) in Hypertension
In this research study, the goal is to find out if a currently FDA-approved medication called Tekturna(Aliskiren) along with the addition of Vitamin D will lower blood pressure and improve heart function in the African American…
- Trial name
- VDATH (NCT01472796)
- Testing
- Vitamin D (cholecalciferol)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Wayne State University
Hypovitaminosis D, Osteoporosis, Postmenopausal
Effect of Vitamin D and Denosumab on Bone Remodelling in Women With Postmenopausal Osteoporosis
Denosumab is a monoclonal antibody against RANKL ligand, which is used as an alternative treatment for osteoporosis in patients who have a poor response to first-line antiresorptive therapy.
- Conditions
- Hypovitaminosis D, Osteoporosis, Postmenopausal, Menopause
- Trial name
- NCT05372224
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 55 people
- Sponsor
- Hospital Regional 1o de Octubre
Diabetes Mellitus, Vitamin D Deficiency
The Effects of Vitamin D Supplementation on Patients With Type 2 Diabetes and Vitamin D Deficiency
Vitamin D plays a key role in keeping normal mineral balance and maintaining bone health. There is accumulating evidence linking deficient vitamin D status with both type 1 and type 2 diabetes.
- Trial name
- VDD (NCT01991054)
- Testing
- vitamin D3
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- HaEmek Medical Center, Israel
Vitamin D Deficiency
Challenges in Achieving Adequate Vitamin D Status in the Adult Population/ Part 2
The efficiency of different vitamin D formulations in treating suboptimal vitamin D status in adult population will be determined. It will provide insights into the influence of formulation on vitamin D absorption.
- Trial name
- VITAD/2 (NCT03810261)
- Testing
- Oil-based vitamin D, Water-based vitamin D, Vitamin D capsules
- Where
- Slovenia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Type 2 Diabetes, Vitamin D Deficiency
African American Children, Glycemic Control, and Type 2 Diabetes
Using a randomized, placebo-controlled trial design in subjects with vitamin D deficiency, the investigators propose to determine if vitamin D treatment improves glycemic control in vitamin D deficient subjects with T2DM.
- Trial name
- ACT (NCT01325987)
- Testing
- Vitamin D2, Sugar pill
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Alabama at Birmingham
Vitamin D Deficiency
Maternal Vit D Supplements & Infant and Maternal Biomarkers & Outcomes in Southern Ethiopia
Synthesis of vitamin D in the skin through the action of sunlight is a major source of vitamin D in parts of the world where foods are not fortified with the vitamin.
- Trial name
- NCT02210884
- Testing
- Vitamin D
- Where
- Ethiopia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Polycystic Ovary Syndrome, Insulin Resistance
Endocrine and Menstrual Disturbances in Women With Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive age women, which causes disordered follicle growth and ovulation resulting in infertility.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Vitamin D Deficiency, Obesity
- Trial name
- EMDPCOS (NCT03652987)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- St George's, University of London
Vitamin D, Iron Deficiency and Overload
Can Vitamin D Replacement Correct Chronic Disease Anemia?
This prospective, single-arm interventional pilot study evaluated whether vitamin D supplementation alone improves iron status in adults with inflammatory bowel disease (IBD) who are in clinical remission and have concurrent…
- Conditions
- Vitamin D, Iron Deficiency and Overload, Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)
- Trial name
- NCT07673497
- Testing
- Cholecalciferol (Vit D3)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Gazi University
X-linked Hypophosphatemia, Hypophosphatemic Rickets
X-linked Hypophosphatemia Disease Monitoring Program
The objectives of this observational study are to characterize XLH disease presentation and progression and to assess long-term effectiveness and safety of burosumab.
- Trial name
- NCT03651505
- Testing
- No intervention
- Where
- 38 sites in United States, Argentina and 4 more
- Volunteers
- 782 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Diabetes Mellitus Type 2, Hypovitaminosis D
Diabetes Intervention Trial With Vitamin D in Subjects of Nordic and Sub-Indian Ethnicity
The aim of this 6 months study is to evaluate the metabolic effects of 400.000-600.000 IU of vitamin D supplementation in subjects with type 2 diabetes and hypovitaminosis D.
- Trial name
- DIVINE (NCT00992797)
- Testing
- Cholecalciferol, Orange juice
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital, Aker
Hydroxylase Deficiency
Influence of Kidney Performance and Magnesium on Formation of (OH)2-vitamin D3
Retrospective database analysis. The target values are the serum values of 25(OH)D, of 1,25(OH)2D, of magnesium and creatinine as well as age and sex of the patients. The laboratory values of the years 2017 and 2018 are included.
- Trial name
- NCT04237480
- Testing
- serum value 1,25(OH)2 vitamin D
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
X-linked Hypophosphatemia (XLH)
Effective Dosing of Burosumab in XLH
X-linked hypophosphataemia (XLH) is a rare, hereditary condition. The genetic defect leads to low blood phosphate levels and vitamin D suppression. Phosphate is required for strong bones and teeth and to store energy in cells.
- Trial name
- NCT07183579
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
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