Clinical trials: Deficiency, Vitamin D
Hypertension, Vitamin D Deficiency
DAYLIGHT: Vitamin D Therapy in Individuals at High Risk of Hypertension
This is a randomized, double-blind, multicenter, 6-month follow-up trial of low (400 IU/day) versus high (4000 IU/day) dose vitamin D supplementation in individuals with pre- and early stage 1 hypertension and vitamin D…
- Conditions
- Hypertension, Vitamin D Deficiency, Pre-Hypertension
- Trial name
- DAYLIGHT (NCT01240512)
- Testing
- Cholecalciferol
- Where
- 3 sites in United States
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Spinal Cord Injury, Vitamin D Deficiency
Vitamin D Deficiency and Replacement on Pulmonary and Endocrine Function in SCI
Studies have shown that individuals who have suffered a spinal cord injury are at an increased risk of Vitamin D deficiency compared to able-bodied individuals.
- Trial name
- NCT02099955
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Adverse Drug Events, Adverse Drug Reactions
YouScript IMPACT Registry
This multicenter observational study aims to investigate the benefits of providing pharmacogenetic testing with the YouScript Personalized Prescribing System which includes a clinical decision support tool and individualized…
- Conditions
- Adverse Drug Events, Adverse Drug Reactions, Drug Interaction Potentiation, Drug Metabolism, Poor, CYP2D6-RELATED
- Trial name
- IMPACT (NCT02191358)
- Where
- 7 sites in United States
- Volunteers
- 800 people
- Sponsor
- Genelex Corporation
Vitamin D Deficiency, Hypovitaminosis A
A Randomized Controlled Trial Testing The Effect Of A Multi-Nutrient Fortified Juice
The goal of this investigator-initiated study is to determine whether the fortification of orange juice with vitamin D, vitamin A, and vitamin E will enhance the vitamin D, vitamin A, and vitamin E status children ages 6-10 that…
- Conditions
- Vitamin D Deficiency, Hypovitaminosis A, Vitamin E Deficiency
- Trial name
- NCT01909063
- Testing
- Vitamin D, Vitamin D, Vitamin E, and Vitamin A, Control, 700 mg Calcium
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Boston University
Hypocalcemia, Vitamin D Deficiency
The Impact of Vitamin D Deficiency on Hypocalcaemia Following Total Thyroidectomy
Post-operative hypocalcaemia following total thyroidectomy is a well-known complication and becoming a major area of research. Many factors are assumed to increase the incidence of post-thyroidectomy hypocalcaemia, but the impact…
- Trial name
- NCT03063060
- Testing
- vitamin D levels and Calcium levels examination
- Volunteers
- 60 people
- Sponsor
- Hillel Yaffe Medical Center
Vitamin D Deficiency
Effects of Vitamin D Fortification on Vitamin D Metabolite Profiles and Status in Vitamin D Insufficient Individuals
This is a cross-sectional study designed to compare plasma/serum and urine vitamin D metabolite profiles of vitamin D sufficient and insufficient individuals. There are two phases of this study.
- Trial name
- VITD-2013 (NCT02422784)
- Testing
- Rooibos Iced-Tea (Control), Rooibos Tea - Vitamin D3, Rooibos Tea- Vitamin D3 & Calcium
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Vitamin D Deficiency, Preterm Infants
Vitamin D Supplementation for Extremely Preterm Infants
The study hypothesis states that giving early enteral Vitamin D supplementation to preterm infants will decrease respiratory morbidity in extremely preterm infants.
- Conditions
- Vitamin D Deficiency, Preterm Infants, Bronchopulmonary Dysplasia
- Trial name
- NCT01600430
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Vitamin D Deficiency
Vitamin D Supplementation in Overweight/Obese African American Adults and Youth (D-SUNNY)
Primary Specific Aim 1: To compare the dose-responsive effects of vitamin D3 supplementations on 25(OH) D, parathyroid hormone (PTH), and serum/urine calcium.
- Trial name
- D-SUNNY (NCT01583621)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Augusta University
Vitamin B6 Deficiency
Vitamin B6 Effects for Women Taking Birth Control Pills
Chronically inadequate B6 nutritional status is associated with aberrant one-carbon (1C) metabolism and health. Plasma pyridoxal phosphate (PLP) >30 nmol/L often has been considered to be the cutoff indicative of nutritional…
- Trial name
- NCT01128244
- Testing
- Vitamin B6, Infusion of labeled serine, methionine and leucine
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Florida
Vitamin D Deficiency
Maternal Vit D Supplements & Infant and Maternal Biomarkers & Outcomes in Southern Ethiopia
Synthesis of vitamin D in the skin through the action of sunlight is a major source of vitamin D in parts of the world where foods are not fortified with the vitamin.
- Trial name
- NCT02210884
- Testing
- Vitamin D
- Where
- Ethiopia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Vitamin D Deficiency, Preterm Infants
Multi-dose Vitamin D Supplementation in Preterm Infants
Preterm newborns are born with lower vitamin D stores. Although vitamin D supplementation is recommended there is no consensus regarding the adequate dose of supplementation for preterm infants.
- Trial name
- NCT02941185
- Testing
- Devit-3 Oral Drop
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Vitamin D Deficiency
Safety of Vitamin D Supplementation in Older Persons
This study will evaluate the safety over 6 months of two different doses of vitamin D (cholecalciferol) in men and women age 65 and older. It will also evaluate if supplementation with vitamin D improves physical performance.
- Trial name
- NCT00681590
- Testing
- cholecalciferol (vitamin D)
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Miami
Type 2 Diabetes, Nonalcoholic Fatty Liver Disease
Hepatic Dysfunction, Vitamin D Status, and Glycemic Control in Diabetes
This study is designed to study the effect of vitamin D intake on the severity of fatty liver and poor glucose control in patients with type 2 diabetes and fatty liver disease.
- Conditions
- Type 2 Diabetes, Nonalcoholic Fatty Liver Disease, Vitamin D Deficiency
- Trial name
- VDLS (NCT02132442)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Massachusetts, Worcester
Vitamin D Deficiency, Nephrolithiasis
The Effect of Vitamin D on Urinary Calcium Excretion in Kidney Stone Formers With High Urinary Calcium
The investigators hypothesize that a 3 month course of vitamin D supplementation to treat 25(OH)D deficiency in stone formers with high levels of 24-hour urinary calcium will not increase urinary calcium excretion by greater than…
- Trial name
- NCT00948740
- Testing
- vitamin D (ergocalciferol)
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Atrial Fibrillation, Venous Thromboses
Pharmacogenetic Dosage Algorithm for Acenocoumarol
The use of coumarins has been a challenge for doctors because of its narrow therapeutic range and they show great inter and intra-individual variability in the dose necessary to achieve an international normalized ratio (INR)…
- Conditions
- Atrial Fibrillation, Venous Thromboses, Cardiac Valve Disease
- Trial name
- NCT03015025
- Testing
- Acenocoumarol
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Thromboembolism
Genetics Informatics Trial (GIFT) of Warfarin to Prevent DVT
Blood clots contribute to the death of at least 100,000 Americans each year. Because many of these deaths occur suddenly where treatment is impossible, the best treatment is prevention.
- Trial name
- GIFT (NCT01006733)
- Testing
- Pharmacogenetic, Target INR 1.8
- Where
- 6 sites in United States
- Volunteers
- 1,598 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Vitamin D Deficiency (10 ng/mL to 30 ng/mL)
Vitamin D as a Supplement Against Falls in Elderly Study
The role of vitamin D deficiency on increased risk for falls and physical dysfunction is unclear. It is also unclear if taking vitamin D improves physical function and reduces fall risk in older adults.
- Trial name
- D-SAFE (NCT01827345)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Florida
Frail Elderly, Vitamin d Deficiency
Vitamin D in Vulnerable Adults (VIVA-VA)
Vitamin D insufficiency is a problem of growing concern, given its prevalence in older persons and the association of low vitamin D with multiple major health problems, including mobility and balance deterioration and falls…
- Trial name
- VIVA-VA (NCT01170273)
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
HIV Infections, Vitamin A Deficiency
Vitamin A to Reduce HIV in Vaginal Secretions and Prevent Viral Transmission
HIV infected individuals with vitamin A deficiency may be more likely to transmit the virus to others than HIV infected individuals who have normal levels of vitamin A.
- Conditions
- HIV Infections, Vitamin A Deficiency, HIV Seronegativity
- Trial name
- NCT00053612
- Testing
- Vitamin A
- Volunteers
- 400 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Vitamin D Deficiency
Improving the Understanding of the Response to Vitamin D Supplementation
It is the investigators hypothesis that the current method of evaluating vitamin D status, measuring circulating 25-hydroxy vitamin D is not providing the full metabolic picture, and is therefore inadequate.
- Trial name
- NCT01465178
- Testing
- cholecalciferol
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison