Clinical trials: Deficiency, Vitamin D
Secondary Hyperparathyroidism, Chronic Kidney Disease
Study to Assess Patient Management Practices and Quality of Life With Paricalcitol Capsules in the Treatment of Secondary Hyperparathyroidism in Stage 3-5 Chronic Kidney Disease Patients Not Yet on Dialysis
Paricalcitol capsules (Zemplar®) received marketing authorization in Sweden in late 2007 for the prevention and treatment of secondary hyperparathyroidism in patients with Stage 3 \& 4 Chronic Kidney Disease (CKD).
- Trial name
- CAPITOL (NCT01265992)
- Where
- 10 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Vitamin D Deficiency
Vitamin D Dose-Response Study to Establish Dietary Requirements in Infants
The research team is comprised of an expert nutrition scientist and a pediatrician with expertise in endocrinology. Both have world-class experience in assessing bone mass in infancy.
- Trial name
- NCT00381914
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- McGill University
Secondary Hyperparathyroidism, Chronic Kidney Disease Mineral and Bone Disorder
Impact of Parathyroidectomy on Cardiovascular Calcification in Dialysis-dependent Patients
This is a prospective cohort study aimed to evaluate change of cardiovascular calcification after parathyroidectomy in patients with end-stage renal disease on dialysis compared with control group on conservative treatment.
- Conditions
- Secondary Hyperparathyroidism, Chronic Kidney Disease Mineral and Bone Disorder, Vascular Calcification, Dialysis
- Trial name
- NCT03937349
- Where
- Russia
- Volunteers
- 63 people
- Sponsor
- Saint Petersburg State University, Russia
Overweight and Obesity, Overweight Adolescents
Efficacy of Oral Vitamin D Supplementation in Adolescents and Young Adults.
This study assesses whether oral supplementation with vitamin D contributes to the reduction of body mass index and lipid profile in adolescents and young adults.
- Conditions
- Overweight and Obesity, Overweight Adolescents, Vitamin D Deficiency
- Trial name
- SIMBAIII (NCT04377386)
- Testing
- 1000 IU D vitamin, 200 IU D vitamin
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundación Cardiovascular de Colombia
Anemia, Hemodialysis Complication
Cholecalciferol Supplementation in Hemodialysis Patients
This is prospective single-blind randomized study, in Ain Shams University hospital) in Egypt, to assess the impact of Cholecalciferol on Anemia status in regular hemodialysis outpatients
- Conditions
- Anemia, Hemodialysis Complication, Vitamin D Deficiency
- Trial name
- NCT05922696
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Vitamin D Status
Hypovitaminosis D Prediction Score
Vitamin D has effects on many tissues, and hypovitaminosis D is frequent. In a French survey conducted among 1587 adults, vitamin D insufficiency (<30ng/ml) has been reported in 80% of subjects, including 43% with moderate…
- Trial name
- SCOPYD (NCT02822651)
- Testing
- Blood sampling, self-administered questionnaire
- Where
- France
- Volunteers
- 2,592 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Breast Cancer
Study of Vitamin D Supplementation Tailored to Vitamin D Deficiency in Breast Cancer Patients
The purpose of this study is to compare normalization of vitamin D serum level after 6 months of vitamin D supplementation adjusted to baseline vitamin D serum level vs.conventional vitamin D supplementation.
- Trial name
- VITACAL (NCT01480869)
- Testing
- calcium and cholecalciferol
- Where
- France
- Volunteers
- 215 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
X-Linked Hypophosphatemia
Efficacy and Safety of Burosumab Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With XLH
The primary objective of this study is to evaluate the effect of KRN23 (burosumab) therapy in improving rickets in children with XLH compared with active control (oral phosphate/active vitamin D).
- Trial name
- NCT02915705
- Testing
- burosumab, Oral Phosphate Supplement, active vitamin D
- Where
- 16 sites in United States, Australia and 5 more
- Volunteers
- 61 people
- Sponsor
- Kyowa Kirin, Inc.
Hip Fracture, Vitamin D Deficiency
The Effect of Supplementation of Vitamin D Deficiency in Older People With Acute Hip Fracture:
This study will be done to evaluate the effect of load dose of vitamin D compared to the dose of usual clinical practice, in improving mobility and reducing disability in older people following a hip fracture.
- Trial name
- VITAMINA_D (NCT03213886)
- Testing
- Calcifediol (Vitamin D)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Leonor Cuadra Llopart
Vitamin D Deficiency (10 ng/mL to 30 ng/mL), Athletes
High-Dose Vitamin D Supplementation and Exercise Effects on Vitamin D Metabolites in Professional Football Players
This randomized, single-blind, placebo-controlled pilot study investigated the effects of high-dose vitamin D₃ supplementation and football-specific physical exercise on vitamin D metabolite concentrations in professional male…
- Conditions
- Vitamin D Deficiency (10 ng/mL to 30 ng/mL), Athletes, Football Players, Exercise Physiology
- Trial name
- VitD-Football (NCT07310329)
- Testing
- Vitamin D₃
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Coronavirus Disease 2019 (COVID-19)
Increased Risk of Severe Coronavirus Disease 2019 in Patients With Vitamin D Deficiency
In this prospective observational study we aim to study the association of vitamin D deficiency with adverse clinical outcomes in patients infected with Coronavirus disease 2019
- Trial name
- COVIT-D (NCT04403932)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital San Carlos, Madrid
Vitamin D Deficiency, End Stage Renal Disease
A Study of 25-hydroxy Vitamin d Levels in Non-itching Hemodialysis Patients
Hypothesis: 25-hydroxy vitamin D levels in non-itching hemodialysis (HD) patients will be higher than those in HD patients with itching 25-hydroxy vitamin D levels will be measured in non-itching hemodialysis patients and…
- Trial name
- NCT01548716
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Winthrop University Hospital
Vitamin D Deficiency
The Effects of Vitamin D3 Alone and in a Combination With Omega-3 on the Association of C-peptide With Glycemic Control
The Effects of Vitamin D3 alone and in a combination with omega-3 on the association of C-peptide with glycemic control
- Trial name
- NCT04307784
- Testing
- VD3, Omega-3FA, VD3 and Omega-3FA
- Where
- Jordan
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Pre-Eclampsia, Depression
Preeclampsia Research on Vitamin D, Inflammation, & Depression
This study is designed to comprehensively investigate the anti-inflammatory role of vitamin D in reproductive aged women, and its association with preeclampsia and depression.
- Conditions
- Pre-Eclampsia, Depression, Inflammation, Vitamin D Deficiency
- Trial name
- PROVIDE (NCT03018132)
- Testing
- mental health screening, education and referral program
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Vitamin D Deficiency, Pregnancy
Vitamin D Status of Pregnant Women and Their Children in Eau Claire, South Carolina
Science News (October 2004) called vitamin D deficiency a "silent epidemic" in America, with no group unaffected. Using new guidelines of optimal vitamin D levels, more than 90% of African American women now suffer from vitamin D…
- Trial name
- NCT00412087
- Testing
- cholecalciferol (vitamin D3), cholecalciferol
- Where
- United States
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Triple Negative Breast Cancer, Vitamin D Deficiency
Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
A two arm pilot study investigating the rate of pathologic complete response in patients with vitamin D deficiency and triple negative breast cancer undergoing standard neoadjuvant chemotherapy + vitamin D supplementation…
- Conditions
- Triple Negative Breast Cancer, Vitamin D Deficiency, Invasive Breast Cancer
- Trial name
- NCT04677816
- Testing
- Standard of Care Neoadjuvant Chemotherapy (NAC), Vitamin D3, Drug Diary
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Non-allergic Asthma, Obesity
Effects of Vitamin D Supplementation in Adolescents With Asthma, Obesity and Vitamin D Deficiency.
Obesity has been associated with a specific non-allergic asthma phenotype and to a deficiency of vitamin D in at least 90% of the pediatric population.
- Conditions
- Non-allergic Asthma, Obesity, Vitamin D Deficiency
- Trial name
- NCT05431920
- Testing
- Vitamin D₃ (25-hydroxy vitamin D)
- Where
- Mexico
- Volunteers
- 264 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Vitamin D Deficiency
Effect of Aerobic Interval Training With Vitamin D Supplement on Functional Capacity and Perceived Myalgia
This study aimed to investigate whether there will be an effect of adding a program of aerobic interval training in managing patients suffering from myalgia associated with vitamin D deficiency.
- Trial name
- NCT04319289
- Testing
- aerobic interval training and Vitamin D supplementation,, Vitamin D supplementation only, aerobic interval training only
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Vitamin D Deficiency, Falls
Study To Understand Fall Reduction and Vitamin D in You
Vitamin D supplements might substantially reduce the risk of falls, potentially by more than 25%. The proposed study is a clinical trial that will determine the effects of 4 doses of vitamin D (200 International Units [IU]/day…
- Trial name
- STURDY (NCT02166333)
- Testing
- 200 IU/d cholecalciferol, 1000 IU/d cholecalciferol, 2000 IU/d cholecalciferol
- Where
- 2 sites in United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Bullosa Epidermolysis, Vitamin D Deficiency
Vitamin D Status and Bone Metabolism Status in Children With Congenital Epidermolysis Bullosa
This retrospective prospective study is aimed at studying the level of vitamin D supply and identifying markers of bone tissue remodeling in order to develop approaches to the prevention of osteopenia and osteoporosis in children…
- Conditions
- Bullosa Epidermolysis, Vitamin D Deficiency, Osteoporosis, Osteopenia
- Trial name
- NCT05141838
- Testing
- Vitamin D, Oral nutritional supplement
- Where
- Russia
- Volunteers
- 110 people
- Sponsor
- National Medical Research Center for Children's Health, Russian Federation
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