Clinical trials: Deficiency, Vitamin D
Vitamin D Deficiency
Efficacy of Vitamin D Therapy on Glucose Homeostasis in Obese Adolescents
The purpose of this study is to see whether giving a Vitamin D supplement to vitamin D deficient obese children and adolescents will decrease the risk of getting diabetes (Disease in which the person has high blood sugar).
- Trial name
- NCT02414529
- Testing
- Vitamin D2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Insulin Resistance
Effect of Vitamin D Supplementation on Oral Glucose Tolerance Among Obese Adolescents
Childhood obesity is a rapidly growing epidemic in the US and the world. Current estimates suggest that 30% of our nation's children are either overweight ot obese.
- Trial name
- NCT01856946
- Testing
- 4,000 IU vitamin D3
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Chronic Renal Insufficiency, Proteinuria
The Effects of Vitamin D Repletion in Vitamin D Deficient Patients With Stage 3 and 4 Chronic Kidney Disease
A randomized clinical trial to determine if vitamin D repletion in CKD (Chronic Kidney Disease) patients with low vitamin D levels will decrease proteinuria, a marker of kidney damage.
- Trial name
- NCT01029002
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Albert Einstein College of Medicine
Vitamin D Deficiency, Primary Open- Angle Glaucoma
Associations of Vitamin D Deficiency and Vitamin D Receptor Polymorphisms With the Risk of Primary Open-angle Glaucoma
This study investigated whether vitamin D receptor gene polymorphism is altered in primary open-angle glaucoma subjects carrying the risk allele and vitamin D deficiency is an important factor in the development of glaucoma.
- Trial name
- NCT02539745
- Testing
- Vitamin D receptor polymorphic analysis, Serum levels of 1a, 25-Dihydroxyvitamin D3
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lv Yingjuan
HIV Disease, Vitamin D Deficiency
Vitamin D Supplementation in HIV-infected Youth
Along with its effects on bone metabolism, vitamin D is an important modulator of the immune system. Experimental studies have shown that the active metabolite of vitamin D [1,25(OH)2D] is able to skew the T cell compartment into…
- Conditions
- HIV Disease, Vitamin D Deficiency, Hypovitaminosis D, Hyperparathyroidism
- Trial name
- NCT01656070
- Testing
- oral cholecalciferol 1000000 UI (vitamin D3)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Oral Lichen Planus, Vitamin D Deficiency
The Role of Vitamin D in Amelioration of Oral Lichen Planus and Its Effect on Salivary IFN-γ Level
The goal of this clinical trial is to compare between the use of vitamin D supplement in conjunction with systemic steroids versus the use of systemic steroids alone in the management of patients with symptomatic Oral Lichen…
- Trial name
- NCT06204796
- Testing
- vitamin D supplement was given as 60,000 IU weekly in conjunction with systemic prednisone, Systemic prednisone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Longitudinal Effect of Vitamin D3 Replacement on Cognitive Performance and MRI Markers in Multiple Sclerosis Patients
This is a longitudinal single blind randomized trial to test the effects of high compared to low dose vitamin D3 supplementation on cognitive performance at 6 and 12 months, and MRI measures of 12 months duration.
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Clinically Isolated Syndrome, Clinically Isolated Syndrome, CNS Demyelinating
- Trial name
- NCT03610139
- Testing
- Vitamin D3
- Where
- Lebanon
- Volunteers
- 162 people
- Sponsor
- American University of Beirut Medical Center
Irritable Bowel Syndrome, Vitamin D Deficiency
Vitamin D Supplementation in IBS
Irritable bowel syndrome (IBS) is a very common functional gastrointestinal disorder affecting nearly 20% of the North American population.
- Conditions
- Irritable Bowel Syndrome, Vitamin D Deficiency, Abdominal Pain
- Trial name
- NCT03148288
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Beth Israel Deaconess Medical Center
Coronary Artery Disease, Postprandial Hyperglycemia
Vitamin D Supplementation in CAD and Postchallenge Hyperglycemia
The main aim of the investigation is to clarify, whether vitamin D supplementation in coronary artery disease patients with vitamin D deficiency and postchallenge hyperglycemia has an impact on endothelial dysfunction and…
- Conditions
- Coronary Artery Disease, Postprandial Hyperglycemia, Vitamin D Deficiency
- Trial name
- NCT01183442
- Testing
- vitamin D
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Medical University of Graz
Hypophosphatasia
Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)
This clinical trial was conducted to study hypophosphatasia (HPP), a bone disorder caused by gene mutations or changes. These gene mutations cause low levels of an enzyme needed to harden bone.
- Trial name
- NCT01176266
- Testing
- asfotase alfa
- Where
- 23 sites in United States, Australia and 10 more
- Volunteers
- 69 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Vitamin D Deficiency, Major Trauma
Vitamin D for Critically Traumatic Patients
Trauma has been an important global public health issue. Yet it is the sixth cause of death in Taiwan, trauma brings great negative impact to national productivity since it presents specifically as the leading cause of death for…
- Trial name
- NCT05449522
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Heart Failure, Vitamin D Deficiency
Effect of Vitamin D Supplementation in Patients With Heart Failure and Vitamin D Deficiency
The purpose of this study is to determine the effects of vitamin D supplementation in patients with heart failure and vitamin D deficiency on ventricular function, inflammatory cytokines, brain natriuretic peptide, lipid profile…
- Trial name
- NCT02087683
- Testing
- Vitamin D Supplementation
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Vitamin D Deficiency
Vitamin D Supplementation Requirement in Obese Subjects
Vitamin D deficiency is common in obese patients. Most of vitamin D supplementation studies were done with non-obese subjects. This study looks at vitamin D supplementation requirements in obese patients as compared to non-obese…
- Trial name
- NCT00996866
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Winthrop University Hospital
Acne Vulgaris, Vitamin D Deficiency
Impact of COVID-19 Vaccination on Serum 25-hydroxyvitamin D Level
Vitamin D plays a pivotal but still not well understood role in the immune response to coronavirus disease (COVID-19) infection and vaccination.
- Conditions
- Acne Vulgaris, Vitamin D Deficiency, COVID-19
- Trial name
- NCT05398939
- Testing
- Blood test and skin evaluation
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Crohn's Disease, Vitamin D Deficiency
Exploring the Effects of Caltrate Supplement on the Chronic Course of Crohn's Disease Patients With Vitamin D Deficiency
Aims:Prospectively observe the effects of Caltrate supplementation on the chronic course of Crohn's disease patients, analyze whether the effect of Caltrate on CD patients is affected by factors such as disease site, disease…
- Conditions
- Crohn's Disease, Vitamin D Deficiency, Vitamin D Supplement
- Trial name
- NCT04276636
- Testing
- Caltrate Pill
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Cardiovascular Disease, Vitamin D Deficiency
Acute Effect of Systemic Stress on Measured Blood Concentrations of 25 (OH) Vitamin D
Each patient who is admitted for preoperative preparation for elective open heart surgery at Intermountain Medical Center will be invited to participate in this study.
- Trial name
- ASSESS-D (NCT02460211)
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Intermountain Health Care, Inc.
Secondary Hyperparathyroidism, Chronic Kidney Disease
The Effect of Diuretics on Mineral and Bone Disorder in Chronic Kidney Disease Patients
Chronic kidney disease (CKD) patients often have associated systemic hypertension due to volume retention, as one of the mechanisms, therefore the use of diuretics is widespread in this population.
- Trial name
- NCT03082742
- Testing
- Hydrochlorothiazide, Furosemide
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- University of Sao Paulo General Hospital
Vitamin D Deficiency
The Influence of Food Matrix Delivery System on the Bioavailability of Vitamin D3
This study investigates the influence of different food matrices on the bioavailability of vitamin D. Although most vitamin D comes from skin synthesis in response to sun exposure, dietary intake is also important - especially…
- Trial name
- DFORT (NCT03783273)
- Testing
- Vitamin D3, Whey protein-complex, Water
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Osteogenesis Imperfecta, Rare Bone Disorders
Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis
MOSAIC aims to determine whether oro-dental morphological anomalies, particularly palatal morphology, associated with rare bone and cartilage diseases can be precisely characterized using 3D digital models analysed through…
- Conditions
- Osteogenesis Imperfecta, Rare Bone Disorders, Hypophosphatemia, X-Linked
- Trial name
- MOSAIC (NCT07666269)
- Testing
- intra-oral 3D optical impression
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Heart Failure With Reduced Ejection Fraction, Vitamin D Deficiency
Supplementation With Vitamin D to Patients With Heart Failure (D-Heart).
In 200 patients with documented systolic heart failure give supplementation with vitamin D in those with a 25-OH- vitamin D < 50nmol/L - or placebo.
- Trial name
- D-Heart (NCT03289637)
- Testing
- Vitamin D
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Linkoeping University
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