Clinical trials: Deficiency, Vitamin D
Vitamin D Deficiency
Optimization of Blood Levels of 25(OH)-Vitamin D in African Americans
Two-thirds of the US population, particularly African Americans (AA), is at risk for inadequate or deficient 25-hydroxy-vitamin D (25(OH)VD).
- Trial name
- NCT04939792
- Testing
- Vitamin D, Vitamin D + L-cysteine, L-cysteine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Chronic Renal Insufficiency, Renal Osteodystrophy
Clinical Observation on Bone Metabolism Induced by Chronic Renal Insufficiency
Patients with chronic renal insufficiency usually develop secondary osteoporosis or bone loss, which is called renal osteodystrophy.
- Trial name
- NCT02147782
- Where
- 4 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Vitamin D Deficiency
Effect of Vitamin D Treatment on Fatigue
Primary objective -Change in Fatigue Assesment Score (FAS) between the first visit (baseline) and 28 (+maximum 7) days after oral administration of 100 000 E vitamin D (Cholecalciferol).
- Trial name
- NCT02022475
- Testing
- Vitamin D
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Crohn's Disease, Vitamin D Deficiency
Trial of High Dose Vitamin D in Patient's With Crohn's Disease
Crohn's disease is more common in areas of the world with less sunlight exposure. Sunlight is a major source of vitamin D. There is some research to suggest that patient's with higher vitamin D levels are less likely to undergo…
- Trial name
- RODIN-CD (NCT02208310)
- Testing
- Cholecalciferol 10,000 IU, Cholecalciferol 400 IU
- Where
- 4 sites in United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
Nephrolithiasis, Urolithiasis
Vitamin D Repletion in Stone Formers With Hypercalciuria
Vitamin D plays a critical role in maintaining bone health, as well as preventing cardiovascular disease, cancer, and various autoimmune diseases, such as diabetes.
- Conditions
- Nephrolithiasis, Urolithiasis, Idiopathic Hypercalciuria, Vitamin D Deficiency
- Trial name
- NCT01295879
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York Presbyterian Hospital
Disorder of Bone Density and Structure, Unspecified, Vitamin D Deficiency
Nutritional Deficiencies Preventive Treatment Prior to Laparoscopic Sleeve Gastrectomy
This study will examine the effect of providing a structured program of daily nutritional supplements for a 8 weeks of intervention prior to Sleeve Gastrectomy bariatric surgery on bone mass density status and formation of…
- Trial name
- LSG (NCT02483026)
- Testing
- Multi vitamin, vitamin D
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Hadassah Medical Organization
COVID-19, Vitamin D Deficiency
The Effects of a Sublingual Sprayable Microemulsion of Vitamin D on Inflammatory Markers in COVID-19 Patients
This placebo-controlled five-day study will be performed on 100 hospitalized COVID-19 patients with vitamin D insufficiency randomized into two groups.
- Trial name
- NCT05502068
- Testing
- Vitamin D 25 (OH) 12000 IU in the form of a sublingual sprayable microemulsion
- Where
- Latvia
- Volunteers
- 102 people
- Sponsor
- Pauls Stradins Clinical University Hospital
Vitamin D Deficiency, Breast Milk Collection
Vitamin D Sulfates in Breastmilk
Infants The purpose of this study is to measure breastmilk's vitamin D sulfate nutritional value in infant's saliva and digesta (gut).
- Trial name
- NCT06203041
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Vitamin D Deficiency, Pre-Eclampsia
Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia
Vitamin D deficient pregnant ladies were selected and randomized into 2 groups for routine daily dose of multivitamin (400IU vitamin D3) versus maximum safest treatment daily dose (4000IU vitamin D3).
- Trial name
- NCT03101150
- Testing
- 400 IU Vitamin D3, 4000 IU Vitamin D3
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Renal Failure, Kidney Donors
BOne Dysfunction in Donor NEphrectomieS
Most dialysis patients die from vascular disease, which is statistically associated with changes related to chronic kidney disease associated mineral bone disorder (CKD-MBD)3-9.
- Trial name
- BONES (NCT04674397)
- Testing
- Radioisotope GFR test
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Manchester University NHS Foundation Trust
Vitamin D Deficiency in Older Persons
Daily Vitamin D Supplementation Compared to a Loading Dose and Monthly Supplementation in Elderly Nursing Home Residents
Vitamin D deficiency is common in older persons, in particular in residents of nursing homes. This is mainly explained by the fact that older persons do not often go outside in the sunshine.
- Trial name
- VIDIV (NCT01168544)
- Testing
- loading dose Vitamin D and 50.000 IU vit D3/month, loading dose and 25.000 IU vit D3/month, Vitamin D 800 IU /day
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- Rijnstate Hospital
Urolithiasis
Effect of Vitamin D Replacement in Patients With Urolithiasis
When Vitamin D replacement is initiated in patients with history of urolithiasis, there will be higher incidence of hypercalciuria but with careful follow-up of these patients, hypercalciuria could be appropriately managed with…
- Trial name
- NCT01349764
- Testing
- Vitamin D3
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Hypocalcemia
Vitamin D Deficiency and Postoperative Hypocalcemia
Hypocalcemia is a frequent adverse event after thyroidectomy. It is usually related to hypoparathyroidism, but preoperative hypocalcemia, hypomagnesemia or vitamin D deficiency contributes to it.
- Trial name
- NCT01632514
- Testing
- Cholecalciferol
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Anemia, Vitamin D Deficiency
Evaluate the Change in Iron, Vitamin D, and C-Reactive Protein Level (CRP) in a 12 to 24 Week Period
The purpose of this study is to observe changes in iron status and vitamin D status during a 12-24 week supervised training program, specifically males and females between the ages of 30 and 50 years old.
- Trial name
- NCT01328704
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Avera McKennan Hospital & University Health Center
Vitamin D Deficiency
Magnitude of Changes in 25 OH Vitamin D3 Levels After Vitamin D3 Supplementation
Vitamin D deficiency is common world wide. 25 OH vitamin D level is the best indicator of vitamin D status. The determination of the appropriate dose of vitamin D supplement is essential for management of vitamin D deficiency as…
- Trial name
- NCT01170507
- Testing
- vitamin D3 1000 IU orally daily for 5 months, vitamin D3 3000 IU orally daily for 5 months, vitamin D3 5000 IU orally daily for 5 months
- Where
- Saudi Arabia
- Volunteers
- healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
Vitamin D Deficiency
Impact of Vitamin D Supplementation on Cardiometabolic Risk Factors [The Daily D Health Study]
The purpose of this research is to determine what supplemental doses of vitamin D may be necessary to raise serum levels to optimal levels and how vitamin D supplementation and changes in vitamin D status impact cardiovascular…
- Trial name
- NCT01537809
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 691 people, healthy volunteers welcome
- Sponsor
- Tufts University
Vitamin-D Insufficiency
Seasonal Variations in Serum 25-hydroxy Vitamin-D Levels in a Swedish Cohort
The purpose of this study was to study seasonal inter-individual and intra-individual variations in S-25(OH)D and to explore parameters associated with S-25-OHD in healthy Swedish adults.
- Trial name
- NCT02136407
- Where
- Sweden
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Hypophosphatemia, Familial, Hyperparathyroidism
Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic Rickets
The purpose of this study is to determine the effectiveness of paricalcitol, a form of synthetic vitamin D, in lowering parathyroid hormone (PTH) levels and reducing disease symptoms in children and adults with X-linked…
- Trial name
- NCT00417612
- Testing
- Paricalcitol
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Yale University
Hypovitaminosis D
A Study on Oral Vitamin D Megadoses
The purpose of this study is to determine if infrequent administration of oral vitamin D megadoses is effective treatment to maintain serum 25-hydroxyvitamin D(3) above target levels of 50-75 nmol/L.
- Trial name
- NCT01067898
- Testing
- vitamin D3 (cholecalciferol), olive oil, calcium carbonate
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Hypovitaminosis D, Spinal Disease
Analysis of Hypovitaminosis D and Osteopenia/Osteoporosis in Spinal Disease Patients Who Underwent a Spinal Fusion at Illinois Neurological Institute, Peoria, IL., a Retrospective Review From November 1, 2012 to October 31, 2014 and Prospective Pilot From July 1, 2015-June 30, 2016
The purpose of this study is to determine if there is correlation between Vitamin D deficiency and spinal disease/spinal fusion surgery.
- Conditions
- Hypovitaminosis D, Spinal Disease, Osteoporosis
- Trial name
- NCT02534714
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- OSF Healthcare System
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