Clinical trials: Degenerative Arthritis of Hip
Osteoarthrosis
Effect of Methylprednisolone on Immune Signaling in Hip-arthroplasty Patients
The study evaluates the pathophysiological effects of a single dose Methylprednisolone administered prior to total hip-arthroplasty (THA) surgery.
- Trial name
- NCT02542592
- Testing
- Methylprednisolone, Isotonic Sodium Chloride
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis, Avascular Necrosis
Trinity™ BIOLOX Delta™ CoC THR Multi-center Study
To demonstrate the safety and effectiveness of the Trinity™ BIOLOX delta™ Ceramic-on-Ceramic Total Hip System in comparison to the Trinity™ Acetabular Hip System,which is FDA cleared for use in the U.S.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, CDH
- Trial name
- NCT01921309
- Testing
- Trinity CoC Total Hip System, Trinity Ceramic-on-Poly THR
- Where
- 10 sites in United States, United Kingdom
- Volunteers
- 342 people
- Sponsor
- Corin
Osteoarthritis, Hip, Cardiovascular Diseases
Effects of Remote Ischaemic Preconditioning in Cemented Hip Arthroplasty.
Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities.
- Conditions
- Osteoarthritis, Hip, Cardiovascular Diseases, Bone Cement Implantation Syndrome, Kidney Diseases
- Trial name
- PRINCIPAL (NCT06323018)
- Testing
- Remote Ischemic Preconditioning
- Where
- Estonia
- Volunteers
- 200 people
- Sponsor
- University of Tartu
Osteoarthritis, Hip
The Effect of Functional Task Training Combined With Therapeutic Ultrasound on Adults With Hip Osteoarthritis
The aim of this study is to evaluate the effect of a functional task-training program combined with therapeutic ultrasound on pain, strength, gait biomechanics and functionality in adults with hip osteoarthritis.
- Trial name
- NCT02798900
- Testing
- Functional task-training, Therapeutic Ultrasound
- Where
- Colombia
- Sponsor
- Universidad del Rosario
Osteoarthritis, Knee / Osteoarthritis, Hip
Efficacy and Safety of MT-5547 in Patients With Osteoarthritis Accompanied by Moderate to Severe Pain
The objective of this study is to verify the superiority of 16 weeks of MT-5547 treatment to placebo, as evidenced by the WOMAC pain score (the efficacy outcome measure), in patients with osteoarthritis of the knee or hip.
- Trial name
- NCT03245008
- Testing
- MT-5547
- Where
- 27 sites in Japan
- Volunteers
- 626 people
- Sponsor
- Tanabe Pharma Corporation
Hip Arthrosis, Hip Injuries
Retrospective Assessment of the Morphology of Acetabular Defects: A 3D Reconstruction Approach
In this study, we aim to develop a statistical shape model and use it to reconstruct the shape of acetabula with severe defects (Paprosky 3a-3b). This will allow us to visualise and assess the morphology of the missing bone.
- Trial name
- NCT04638140
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hip Osteoarthritis
Prospective Randomised Study of a New an Uncemented Stem.
Patients will be randomised to either operation with a Corail stem or a SP-CL stem. The groups are examined with RSA, conventional x-rays, PROM-data and DXA. First evaluation will be done at two years.
- Trial name
- NCT04599582
- Testing
- Hip Arthroplasty
- Volunteers
- 80 people
- Sponsor
- Sahlgrenska University Hospital
Osteoarthritis, Hip, Osteoarthritis, Knee
Evaluation of Teleconsulting on Rehabilitation After Hip and Knee Surgical Procedures
The objective of this study is to assess the medical and economic relevance of teleconsulting for Rehabilitation After Hip and Knee Surgical Procedures.
- Trial name
- SSRHAD (NCT02229279)
- Testing
- Teleconsulting
- Where
- France
- Volunteers
- 430 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis, Post-traumatic Arthritis
A Randomised Single Centre Study to Compare the Long-term Performance of Acryloc™ and Palacos® R Bone Cements in Primary Total Hip Replacement
The purpose of this study is to monitor the stability of a total hip replacement within the thigh bone when used in artificial hip joints implanted with two different bone cements, Acryloc™ and Palacos® R, in the treatment of…
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT00208403
- Testing
- Acryloc™ GHV, Palacos R
- Where
- Norway
- Volunteers
- 36 people
- Sponsor
- DePuy International
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Expectations, Satisfaction and Quality of Life in Total Hip Arthroplasty
The goals of this study are to identify predictors of improvement in quality of life and satisfaction with total hip arthroplasty three to five years after surgery.
- Trial name
- NCT00197990
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis, Osteoarthritis, Hip
Pericapsular Nerve Group Block Chemical Neurolysis in Advanced Hip Osteoarthritis
PENG neurolysis in advanced osteoarthritis of the hip joint.
- Trial name
- PENG (NCT06087588)
- Testing
- 0.9%sodium chloride, 95% ethanol
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Hip
A Study of the Safety and Effectiveness of Synvisc-One® (Hylan G-F 20) in Patients With Primary Osteoarthritis of the Hip
The primary objective of this study was to demonstrate any changes in assessments of pain for participants receiving Synvisc-One compared to control.
- Trial name
- NCT01618708
- Testing
- Synvisc-One (hylan G-F 20)
- Where
- 48 sites in United States, Canada
- Volunteers
- 357 people
- Sponsor
- Genzyme, a Sanofi Company
Osteoarthritis
Safety of Lumiracoxib in Patients With Osteoarthritis
This safety study evaluated the incidence of gastrointestinal adverse events and edema in patients with osteoarthritis treated with lumiracoxib and rofecoxib as comparator
- Trial name
- NCT00637949
- Testing
- lumiracoxib, rofecoxib
- Volunteers
- 309 people
- Sponsor
- Novartis
Osteoarthritis, Hip
Comparison of Clinical Results of Two Cementless Femoral Stem
In the present study, two types of cementless femoral stem- UTS Stem and UTF-reduced Stem- were utilized in total hip arthroplasty.
- Trial name
- NCT04501185
- Testing
- total hip arthroplasty
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Osteoarthritis, Hip
Dry Needling Versus Stretching for Muscle Extensibility
Hip osteoarthritis (OA) is one of the most prevalent chronic disease in the world. Currently several authors have shown the presence of active myofascial trigger points (MTrP) in the muscles surrounding the hip joint that…
- Trial name
- NCT04400825
- Testing
- Dry needling
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- Universidad de Zaragoza
Osteoarthritis
Massachusetts General Hospital Evaluation of DePuy ASR Hip System
DePuy Orthopaedics has issued a voluntary recall of the ASR hip replacement system due to a higher than expected revision rate reported in the England/Wales and Australian national joint registries.
- Trial name
- NCT01611233
- Where
- 13 sites in United States, Australia and 3 more
- Volunteers
- 1,950 people
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Pain
Study of Efficacy, Safety of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3001
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as adjunctive therapy compared with placebo in participants with chronic moderate to severe pain and functional impairment from knee…
- Trial name
- NCT02336685
- Testing
- Fulranumab 1 mg, Fulranumab 3 mg, Opioid
- Where
- 53 sites in United States, Canada and 4 more
- Volunteers
- 79 people
- Sponsor
- Janssen Research & Development, LLC
Arthrosis, Traumatic Arthritis
The Medacta Quadra-P Anteverted Study
This is a Post-Marketing Surveillance of Quadra-P anteverted stem prosthesis.
- Conditions
- Arthrosis, Traumatic Arthritis, Rheumatoid Polyarthritis, Congenital Hip Dysplasia
- Trial name
- NCT05460715
- Testing
- Quadra P anteverted
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Medacta International SA
Osteoarthritis, Hip, Total Hip Arthroplasty
Development of an Effective Home-based-exercise-strategy
Osteoarthritis is one of the most common chronic diseases of the musculoskeletal system in elderly. Patients with osteoarthritis experience pain, stiffness and loss of mobility.
- Trial name
- NCT03846063
- Testing
- Home-based rehabilitation program
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Osteoarthritis, Hip
Bone Marrow Aspirate Concentrate Use in Hip Osteoarthritis
The purpose of this study is to evaluate the effect of combined Bone marrow aspirate concentrate (BMAC) and Platelet Rich Plasma (PRP) action after a single hip intraarticular injection to young symptomatic patients with primary…
- Trial name
- BMAC (NCT03410355)
- Testing
- BMAC/PRP Injection, Cortisone Injection
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority