Clinical trials: Degenerative Arthritis of Hip
Osteoarthritis, Hip
Effect of Local Infiltration Anesthesia With Ropivacaine on Pain After Primary Total Hip Arthroplasty
Background: The Local infiltration analgesic (LIA) technique has been widely used to reduce opioid requirements and improve the patient's mobilization after total hip arthroplasty (THA).
- Trial name
- NCT02359136
- Testing
- local infiltration anesthesia using Ropivacaine and Epinephrine, local infiltration anesthesia using saline, Multimodal analgesic regimen
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- St. Olavs Hospital
Fracture of Hip, Osteoarthritis, Hip
Mechanical Ventilation Based on Driving Pressure in Lateral Position
Previous studies showed that, best lung protective strategies of ventilation parameters are based on driving pressure in damaged lungs.
- Conditions
- Fracture of Hip, Osteoarthritis, Hip, Congenital Hip Deformity
- Trial name
- NCT04455789
- Testing
- routine lung protective, conventional mechanical ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Osteoarthritis of the Hip
Physical Therapy Prior to Total Knee Replacement
In this study, the investigators are investigating the effects of physical therapy (PT) for treating high grade knee osteoarthritis (OA) in patients that are candidates for total knee replacement.
- Trial name
- NCT02279277
- Testing
- Supervised physical therapy program prior to total knee replacement surgery
- Volunteers
- 148 people
- Sponsor
- Rothman Institute Orthopaedics
Acetabular Labrum Tear, Femoro Acetabular Impingement
Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies
The goal of this clinical trial is to assess the effect of PRP/PPP/BMAC application on functional outcomes after hip arthroscopy to address acetabular labral pathologies. The main questions it aims to answer are: 1.
- Conditions
- Acetabular Labrum Tear, Femoro Acetabular Impingement, Chondral Defect, Bone Marrow Aspirate Concentrate
- Trial name
- PRP; PPP; BMAC (NCT06003101)
- Testing
- Bone marrow aspirate concentrate (BMAC), Control
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Hip, Osteoarthritis, Knee
A Study to Evaluate the Effectiveness and Safety of Slow Release Hydromorphone HCL for Treatment of Patients With Osteoarthritis
The purpose of this study was to compare the analgesic (a drug that relieves pain) effectiveness and safety of OROS hydromorphone HCI (slow release) 8 mg and 16 mg to placebo (no drug) in patients with osteoarthritis (OA).
- Trial name
- NCT00411164
- Testing
- OROS hydromorphone HCI (slow release)
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Alza Corporation, DE, USA
Osteoarthritis, Hip, Fracture of Hip
Post Market Clinical Follow-Up of the Zimmer Stafit Acetabular System
This study is a Post Market Clinical Follow up study to fulfil the post market surveillance obligations according to Medical Device Directive and European Medical Device Vigilance System (MEDDEV) 2.12-2.
- Conditions
- Osteoarthritis, Hip, Fracture of Hip, Avascular Necrosis of Hip, Dislocated Hip
- Trial name
- NCT04079114
- Testing
- Patients who received the Stafit Acetabular System
- Volunteers
- 166 people
- Sponsor
- Zimmer Biomet
Degenerative Joint Disease, Osteoarthritis, Hip
Safety and Effectiveness of the HIT Reverse HRS
The purpose of this study is to determine if the use of the HIT Reverse Hip Replacement System is safe and effective in patients undergoing total hip replacement.
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Hip, Avascular Necrosis of Hip, Traumatic Arthropathy-Hip
- Trial name
- NCT05357378
- Testing
- Hip Innovation Technology Reverse Hip Replacement System, Already-marketed semi-constrained uncemented hip systems using a metal-on-XLPE or ceramic-on-XLPE bearing combination.
- Where
- 6 sites in United States
- Volunteers
- 288 people
- Sponsor
- Hip Innovation Technology
Pain, Osteoarthritis
Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Osteoarthritic Pain
The primary objective of this study is to evaluate the efficacy and safety of BTDS compared to placebo in subjects with moderate to severe osteoarthritic pain of the hip or knee.
- Trial name
- NCT00345787
- Testing
- Buprenorphine Transdermal System
- Where
- 28 sites in Japan
- Volunteers
- 262 people
- Sponsor
- Mundipharma K.K.
Osteoarthritis, Knee
The Influence of Hip Strengthening Exercises on Walking Patterns and Muscle Strength in Persons With Knee Osteoarthritis
The purpose of this study is to determine the influence of a home program of exercises for the hip muscles which support the pelvis on walking patterns and hip muscle strength in people with knee osteoarthritis.
- Trial name
- NCT00427843
- Testing
- home exercise program for the hip abductor muscles
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Queen's University
Post-operative Pain, Acute, Opioid Use, Unspecified
Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care
The goal of this clinical trial is to learn if the Pain Coach App will result in less opioids being prescribed to and used by patients undergoing Shoulder/Hip/Knee Arthroplasty surgery while maintaining the same or better pain…
- Conditions
- Post-operative Pain, Acute, Opioid Use, Unspecified, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT06469177
- Testing
- Pain Coach App
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Osteoarthritis, Osteonecrosis
E-Type - Early Wear of Polyethylene Liners Used in DMC
This is a single-centre, randomized, double-blinded controlled non-inferiority trial that will be conducted at the Orthopaedic Department at Uppsala University Hospital, Uppsala.
- Conditions
- Osteoarthritis, Osteonecrosis, Dysplasia; Hip
- Trial name
- E-type (NCT07863557)
- Testing
- Total Hip Arthroplasty
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
A Clinical Investigation of the M2a- 38™ Hip System
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a- 38™ Hip System
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis
- Trial name
- NCT00698503
- Volunteers
- 190 people
- Sponsor
- Biomet Orthopedics, LLC
Osteoarthrosis, Total Hip Arthroplasty
Clinical Evaluation on the Use of the X-pander Device
The purpose of this study is to clinically evaluate the use of the x-pander device.
- Trial name
- X-Pander (NCT01443975)
- Testing
- x-pander
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis
Comparison of Two Minimally Invasive Surgical Techniques for Hip Replacement
Comparison of the clinical effectiveness and cost-effectiveness of the MIS anterolateral approach (MIS Watson Jones, G3) versus anterolateral mini or posterolateral mini approaches in primary total hip arthroplasty
- Trial name
- NCT00175461
- Testing
- hip surgery
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- University of British Columbia
Degenerative Joint Disease
EU Safety and Efficacy Study Regarding the R3 Acetabular Hip System
The objective of this study is to determine the long-term safety and effectiveness from the R3 Acetabular Hip System. The study hypothesis is that implant survivorship of the R3 cup is at least 97% at 3 years, 95% at 5 years, 93%…
- Trial name
- NCT04399928
- Testing
- Total Hip Arthroplasty
- Where
- 8 sites in Belgium, Denmark and 5 more
- Volunteers
- 479 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Osteoarthritis
Effects of Dry Needling on Muscle Function in Patients With Hip Osteoarthritis
The aim of this study was to assess the effects of dry needling technique on muscle strength and muscle length in patients with hip osteoarthritis at short term.
- Trial name
- NCT04195464
- Testing
- Dry needling
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Universidad de Zaragoza
Arthropathy of Hip, Hip Osteoarthritis
Comparison of Spinal Anesthesia With Intrathecal Morphine Versus PENG Block With or Without Dexamethasone in Hip Arthroplasty
The goal of this clinical trial is to learn which of three regional anesthesia approaches provides better pain relief and safety for older adults having planned hip replacement surgery.
- Trial name
- THA (NCT07584200)
- Testing
- Intrathecal Morphine, Pericapsular Nerve Group Block, Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Avascular Necrosis
Metal on Metal Versus Metal on Highly Crossed Linked Polyethylene Sytem
This trial will evaluate the 36mm or greater metal head on metal hip system and compare it to the 32mm or 28mm metal head on polyethylene (liner) hip system in patients receiving a primary cementless total hip replacement.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Congenital Dysplasia of the Hip
- Trial name
- MOM (NCT01422564)
- Testing
- Metal on Metal Hip System, Highly Cross Linked Polyethylene cup System
- Volunteers
- 41 people
- Sponsor
- Nova Scotia Health Authority
Osteoarthritis of Hip, Osteoarthritis, Knee
Chlorzoxazone in Hip and Knee Arthroplasty
The purpose of this study is to elucidate whether patients operated with THA and TKA can benefit from treatment with chlorzoxazone.
- Trial name
- chlorzoxazon (NCT02405104)
- Testing
- chlorzoxazone, THA, TKA
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the hip.
- Trial name
- NCT02844764
- Testing
- [StroMed + platelet rich plasma (PRP)]
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- VivaTech International, Inc.