Clinical trials: Degenerative Arthritis of Hip
Hip Osteoarthritis, Avascular Necrosis
Insignia™ Hip Stem Outcomes Study
The objective of this study is to evaluate the safety and effectiveness of the Insignia™ Hip Stem for global market access and post-market clinical follow-up up to 10 years postoperative.
- Conditions
- Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
- Trial name
- NCT05144191
- Testing
- Insignia uncemented Hip Stem
- Where
- 11 sites in United States
- Volunteers
- 313 people
- Sponsor
- Stryker Orthopaedics
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Sleep and Pain in Osteoarthritis
People with osteoarthritis and painful joints often report poor sleep, but poor sleep can also increase pain. There have been very few studies of sleep in osteoarthritis using physical measuring devices, but in other painful…
- Trial name
- NCT07821047
- Volunteers
- 73 people
- Sponsor
- University of Reading
Knee Osteoarthritis, Hip Osteoarthritis
An Analysis of the Outcomes From Protocolized Perioperative Care for Patients Receiving Total Hip or Knee Arthroplasty
The care for patients receiving total hip and knee arthroplasty at the University of Arkansas for Medical Sciences has followed a structured care pathway since July 2015.
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Knee Arthritis, Hip Arthritis
- Trial name
- NCT03071250
- Testing
- Total knee or Hip Arthroplasty
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Arkansas
Osteoporosis, Osteoarthritis, Hip
Metabolic Profiling of Hematopoietic Stem Cells in Clonal Hematopoiesis (CHIP)
Bone marrow samples will be collected from patients undergoing hip arthroplasty surgery. Blood and bone marrow samples will be used for metabolic profiling and analysis of relevant CHIP mutations.
- Conditions
- Osteoporosis, Osteoarthritis, Hip, Hip Fractures, Clonal Hematopoiesis of Indeterminate Potential
- Trial name
- NCT05246813
- Testing
- Blood and bone marrow cell collection
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Imelda Hospital, Bonheiden
Osteoarthritis
A Randomised Open Controlled Parallel Group Study Comparing Norspan and Tramadol
To evaluate the efficacy and safety of Norspan versus Tiperol Retard among OA patients who are sub-optimally treated with current analgesic. Those patients may benefit from treatment with a long lasting analgesic.
- Trial name
- NCT00399178
- Testing
- Transdermal delivery system
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Mundipharma AB
Knee Osteoarthritis, Pain
The Effect of Adding Instrumented Hip Concentric Abductor Strengthening Exercise in Knee Osteoarthritis
The aim of this study was to investigate the effectiveness of adding hip device-assisted concentric abductor strengthening (HDACAS) program to knee device-assisted concentric flexor-extensor strengthening (KDACFES) program on…
- Conditions
- Knee Osteoarthritis, Pain, Physical Disability
- Trial name
- NCT06331858
- Testing
- hip device-assisted concentric abductor strengthening (HDACAS), knee device-assisted concentric flexor-extensor strengthening (KDACFES)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kutahya Health Sciences University
Osteoarthritis
RSA Study of Sirius Stem and Exceed Cup
The purpose of this study is to evaluate the efficacy and safety of the Sirius Cemented Stem used in conjunction with the Exceed ABT Cemented Acetabular Cup, either with E1 or Arcom polyethylene, and OptiPac/OptiVac bone cement…
- Trial name
- NCT02307331
- Testing
- Optivac, Optipac, Arcom (Exceed cup)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Region Skane
Osteoarthritis, Hip
Intraoperative IV Iron on Postoperative Red Blood Cell Recovery
The objective of the present study is to determine the impact of intraoperative IV-iron supplementation on postoperative recovery of RBC mass by retrospectively analyzing and comparing the changes of postoperative hematocrit…
- Trial name
- NCT04035902
- Testing
- Ferric carboxymaltose, control
- Volunteers
- 46 people
- Sponsor
- Konkuk University Medical Center
Hip Osteoarthritis
Total Hip Replacement Performance & Assessment
This research study is focused upon assessing and optimising surgeon's performance during, and patient outcomes following, primary total hip replacement (THR) surgery.
- Trial name
- NCT04267172
- Testing
- Surgical simulation training in primary Total Hip Arthroplasty, No intervention: Surgical Resident Control Group, No Intervention: Consultant and Fellow Comparator Group
- Where
- United Kingdom
- Volunteers
- 243 people
- Sponsor
- University of Oxford
Osteoarthritis
Study to Test the Efficacy of Periarticular Levo Bupivicaine Injection Following Primary Hip Arthroplasty
The hypothesis of this study is that isolated use of local periarticular levobupivicaine injection during primary hip arthroplasty would improve post-operative pain control.
- Trial name
- NCT01106001
- Testing
- Levobupivacaine, Saline
- Where
- 2 sites in Ireland
- Volunteers
- 91 people
- Sponsor
- Orthopaedic Research and Innovation Foundation, Ireland
Osteoarthritis, Hip, Arthroplasty, Replacement, Hip
Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen
The primary aim of this randomised trial is to determine the effects of a short peri-operative course of treatment with a non-steroidal anti-inflammatory drug (NSAID), ibuprofen, on the long-term consequences of ectopic bone…
- Conditions
- Osteoarthritis, Hip, Arthroplasty, Replacement, Hip, Arthritis, Rheumatoid
- Trial name
- NCT00145730
- Testing
- Ibuprofen
- Volunteers
- 1,000 people
- Sponsor
- The George Institute
Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck
Z1 Hip System: Post-Market Clinical Follow Up Study
The objectives of this study are to confirm the early to mid- term safety, performance, and clinical benefits of the Z1 Femoral Hip System in hemi- and primary total hip arthroplasty.
- Conditions
- Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
- Trial name
- NCT07104279
- Testing
- Z1 Femoral Hip System
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Hip, Femur Head Necrosis
Efficiency and Safety of Navigation Aids in Total Hip Arthroplasty With Direct Anterior Approach
This retrospective cohort study aimed to evaluate the effectiveness of an imageless navigation system in total hip arthroplasty (THA) via the direct anterior approach (DAA) on a traction table for reducing functional limb length…
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Developmental Dysplasia of the Hip
- Trial name
- NCT07134036
- Testing
- Navigation system, Conventional total hip arthroplasty
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- China Medical University Hospital
Low Back Pain, Hip Osteoarthritis
Observational Study of the Development of Low Back Pain After Total Hip Arthroplasty.
The investigators are going to observe the appearance of low back pain in patients who have undergone hip prosthesis surgery.
- Conditions
- Low Back Pain, Hip Osteoarthritis, Arthropathy of Hip
- Trial name
- NCT05647629
- Testing
- Total hip arthroplasty
- Where
- 2 sites in Spain
- Volunteers
- 618 people
- Sponsor
- Universidad de Zaragoza
Osteoarthritis
Study of OLP-1002 Injections for Reducing Moderate to Severe Pain Due to Osteoarthritis in Hip and/or Knee Joint
The study is designed to evaluate the efficacy, safety and tolerability of OLP-1002 Subcutaneous (SC) injections for reducing moderate to severe pain due to osteoarthritis in a hip and/or knee joint.
- Trial name
- NCT05216341
- Testing
- OLP-1002
- Where
- 7 sites in Australia
- Volunteers
- 134 people
- Sponsor
- OliPass Corporation
Osteoarthritis of Hip
A Study of Posterior Hip Precautions After Total Hip Arthroplasty
The purpose of this study is to perform a randomized controlled study to compare patients undergoing THA via a posterolateral approach to receive either standard of care post-surgery hip restrictions or to receive no…
- Trial name
- HIPPRECAU (NCT03341442)
- Testing
- No hip precautions
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Osteoarthritis, Hip, Total Hip Arthroplasty
Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With OA
Aim: To compare the effect of one single dose versus multiple doses of prophylactic antibiotics administered within 24 hours, on the development of PJI in patients with osteoarthritis undergoing primary THA.
- Conditions
- Osteoarthritis, Hip, Total Hip Arthroplasty, Prosthetic-joint Infection
- Trial name
- ProHipQ-OA (NCT05530551)
- Testing
- Antibiotic dosage practice
- Where
- 36 sites in Denmark
- Volunteers
- 20,000 people
- Sponsor
- Soren Overgaard
Osteonecrosis, Osteoarthritis
Comparison of Ceramic-on-Ceramic and Ceramic-on-Highly-Cross-Linked Polyethylene Bearings
The purpose of this prospective, randomized study was to compare the clinical and radiographic results and the prevalence of osteolysis of the cementless total hip arthroplasty with an alumina-on-alumina bearings one side and…
- Trial name
- NCT01806766
- Testing
- Ceramic on Ceramic bearing, Ceramic on Highly crosslinked polyethylene bearing
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ewha Womans University
Hip Arthropathy, Osteoarthritis, Hip
PROMIS Evaluation Study
A total of 250 total hip arthroplasties (THA) are performed at the Bezirkskrankenhaus St. Johann. In a majority of those, implants from the company Falcon Medical (Austria) are used.
- Conditions
- Hip Arthropathy, Osteoarthritis, Hip, Perthes Disease, Osteonecrosis
- Trial name
- NCT05734651
- Testing
- PROMIS Stem
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Bezirkskrankenhaus St. Johann in Tirol
Rheumatoid Arthritis, Osteoarthritis
An Electronic Data Capture Study to Assess the Long-term Performance of the DePuy PROXIMA™ Hip in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of the DePuy PROXIMA™ hip in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT01134445
- Testing
- DePuy Proxima™ Hip
- Where
- 4 sites in France, Portugal and 2 more
- Volunteers
- 42 people
- Sponsor
- DePuy International