Clinical trials: Degenerative Arthritis of Hip
Hip Osteoarthritis
Evaluation of the Structure Modifying Effect of Avocado-Soybean Unsaponifiables in Hip Osteoarthritis
This study aims to assess the long term (three years) ability of ASU (Avocado Soya unsaponifiable) to slow the decrease of radiographic JSW (Joint Space Width) in hip osteoarthritis (OA).
- Trial name
- ERADIAS (NCT01062737)
- Testing
- ASU
- Where
- France
- Sponsor
- Laboratoires Expanscience S.A.
Osteoarthritis, Avascular Necrosis
Efficacy of the CLP® Hip - Retrospective
The purpose of this study is to evaluate the survivorship and efficacy of the Encore CLP® Hip stem in a group of no more than 200 patients from whom data has already been collected.
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- NCT00764842
- Testing
- Encore CLP® Hip stem
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Encore Medical, L.P.
Osteoarthritis, Arthritis
A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, Compared With Placebo in Patients With Osteoarthritis
The purpose of the study is to determine if fentanyl, delivered through the skin via an adhesive patch, has a superior pain-relieving effect compared with placebo in patients with osteoarthritis pain that is inadequately…
- Trial name
- NCT00236366
- Testing
- fentanyl
- Volunteers
- 418 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Arthritis, Osteoarthritis, Knee
Switching Drug Therapy for the Prevention of Blood Clot Formation From Enoxaparin to Rivaroxaban After Orthopedic Surgery for Either Total Hip or Total Knee Replacement
The study will describe the short-term effects the study drug, rivaroxaban, has on the body when a patient is switched from enoxaparin injection (by needle) to oral rivaroxaban (by mouth) for the prevention of blood clotting in…
- Conditions
- Arthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Thromboembolism
- Trial name
- NCT01094886
- Testing
- Rivaroxaban
- Where
- 5 sites in United States
- Volunteers
- 56 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Osteoarthritis
A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis (0686-006)
This study is being conducted to assess the safety and tolerability of MK-0686 and to evaluate its efficacy in the treatment of osteoarthritis of the hip or knee in men and women.
- Trial name
- NCT00296569
- Testing
- MK0686
- Volunteers
- 150 people
- Sponsor
- Merck Sharp & Dohme LLC
Knee Osteoarthritis, Knee Disease
ESPB vs FICB for Pain Management Following Total Hip Prosthesis Surgery
Hip arthroplasty surgery is frequently performed on elderly patients in the community and it is associated with long-term postoperative hospital stays and high mortality.
- Conditions
- Knee Osteoarthritis, Knee Disease, Knee Arthritis
- Trial name
- NCT05621161
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mursel Ekinci
Osteoarthritis, Hip
Intraoperative IV Iron on Postoperative Red Blood Cell Recovery
The objective of the present study is to determine the impact of intraoperative IV-iron supplementation on postoperative recovery of RBC mass by retrospectively analyzing and comparing the changes of postoperative hematocrit…
- Trial name
- NCT04035902
- Testing
- Ferric carboxymaltose, control
- Volunteers
- 46 people
- Sponsor
- Konkuk University Medical Center
Hip Osteoarthritis
Assess the Mid-term Performance of the Mpact Cup in Subjects Requiring Total Hip Arthroplasty
Monitor the performance of the Mpact cup in the treatment of patients with hip joint disease requiring a total hip replacement.
- Trial name
- NCT03897595
- Testing
- MPact Cup
- Where
- 5 sites in United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Chronic Osteoarthritis
OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects
The primary objectives are to demonstrate that the treatment with OXN PR tablets is non-inferior to the treatment with OxyPR with regards to analgesic efficacy and locomotor function.
- Trial name
- NCT00902837
- Testing
- Oxycodone naloxone prolonged release tablets (OXN), oxycodone prolonged release tablet, oxycodone naloxone tablet
- Where
- 36 sites in Belgium, Czechia and 4 more
- Volunteers
- 181 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Hip Injuries, Coxarthrosis
Balance and Leg Function After Hip Replacement
Task-oriented leg exercise are commonly used after joint surgeries in various hip pathologies. Based on this theory, it was hypothesized that task-oriented exercise without conventional physiotherapy can have better result in…
- Conditions
- Hip Injuries, Coxarthrosis, Hip Replacement
- Trial name
- NCT05343195
- Testing
- Task-oriented exercise, Control
- Where
- Lithuania
- Volunteers
- 40 people
- Sponsor
- Lithuanian Sports University
Hip Osteoarthritis, Knee Osteoarthritis
Face to Face or Digitally Delivered First-line Osteoarthritis Treatment?
This study will compare outcomes of two different delivery methods (Face-to-face and digitally) of first-line treatment for hip and knee osteoarthritis.
- Trial name
- NCT04836988
- Testing
- Three months of digitally delivered osteoarthritis treatment, Three months of face-to-face delivered osteoarthritis treatment
- Where
- Sweden
- Volunteers
- 6,946 people
- Sponsor
- Lund University
Hip Osteoarthritis, Heterotopic Ossification
Balance in Patients With Ectopic Bone Tissue After Total Hip Replacement
One of the typical complications which occurs after total hip replacement (THR) procedure is heterotopic ossification (HO). According to current studies abnormal formation of bone after trauma or replacement of the hip could…
- Conditions
- Hip Osteoarthritis, Heterotopic Ossification, Hip Arthropathy
- Trial name
- NCT05218954
- Testing
- Biomechanical analysis of risk fall
- Where
- Poland
- Volunteers
- 88 people
- Sponsor
- Medical University of Warsaw
Knee Osteoarthritis
Efficacy of Hip Strengthening on Dynamic Knee Stability, Disability and Gait in Knee Osteoarthritis
this study will be conducted to investigate the role of hip strengthening in improving dynamic knee stability, gait parameter, lower extremity strength and disability in knee osteoarthritis
- Trial name
- NCT04509830
- Testing
- hip strengthening, quadriceps strengthening, stretch hamstring,cuff muscles
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis, Hip Osteoarthritis
MRgFUS in the Treatment of Hand and Hip Osteoarthritic Pain
This project aims at performing a pilot study to provide data on safety and potential efficacy of Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) in the treatment of pain caused by trapeziometacarpal osteoarthritis…
- Conditions
- Osteoarthritis, Hip Osteoarthritis, Hand Osteoarthritis
- Trial name
- NCT03467165
- Testing
- MRgFUS treatment
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis
Study of OLP-1002 Injections for Reducing Moderate to Severe Pain Due to Osteoarthritis in Hip and/or Knee Joint
The study is designed to evaluate the efficacy, safety and tolerability of OLP-1002 Subcutaneous (SC) injections for reducing moderate to severe pain due to osteoarthritis in a hip and/or knee joint.
- Trial name
- NCT05216341
- Testing
- OLP-1002
- Where
- 7 sites in Australia
- Volunteers
- 134 people
- Sponsor
- OliPass Corporation
Osteoarthritis, Hip, Osteoarthritis
Conventional Total Hip Arthroplasty vs Mako Robotic-arm Assisted Total Hip Arthroplasty
The overall aim of this single-centre, prospective randomised controlled trial is to compare clinical, functional, and radiological outcomes in CO THA versus Mako THA.
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Surgery
- Trial name
- NCT04095845
- Testing
- CO THA, Mako THA
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University College, London
Osteonecrosis, Osteoarthritis
Comparison of Ceramic-on-Ceramic and Ceramic-on-Highly-Cross-Linked Polyethylene Bearings
The purpose of this prospective, randomized study was to compare the clinical and radiographic results and the prevalence of osteolysis of the cementless total hip arthroplasty with an alumina-on-alumina bearings one side and…
- Trial name
- NCT01806766
- Testing
- Ceramic on Ceramic bearing, Ceramic on Highly crosslinked polyethylene bearing
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ewha Womans University
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Pain
Long-term Safety of PF-00345439 (Oxycodone)
Long-Term Safety Of PF-00345439 (Oxycodone) In Patients With Moderate To Severe Chronic Low Back Pain Or Osteoarthritis
- Trial name
- NCT01559701
- Testing
- PF-00345439
- Volunteers
- 823 people
- Sponsor
- Pain Therapeutics
Chronic Pain, Fibromyalgia
Chronic Pain, Couples, & Physical Activity
Chronic pain affects more than 50 million adults in the United States and is estimated to cost the nation more than $560 billion dollars each year.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04077164
- Testing
- No intervention, observational only.
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Illinois Institute of Technology