Clinical trials: Degenerative Joint Disease
Osteoarthritis Thumb
The Effects of Two Different Orthosis on Pain, Hand Strength and Function in Patients With Thumb Carpometacarpal Osteoarthritis
The investigators aimed to assess the effects of two different hand orthosis on hand functioning, pain, disability and quality of life in patients with thumb osteoarthritis
- Trial name
- NCT03327480
- Testing
- orthosis
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Health Services Accessibility, First-line Treatment
Can Digitally Delivered First-line Osteoarthritis Treatment Improve Equal Access to Care
To improve chronically ill patients' health and quality of life, long-standing and continuous treatment is needed at an acceptable cost.
- Conditions
- Health Services Accessibility, First-line Treatment, Osteoarthritis
- Trial name
- Access (NCT06148779)
- Testing
- Digitally delivered first-line treatment for osteoarthritis, Face-to-face first-line treatment for osteoarthritis
- Where
- Sweden
- Volunteers
- 50,000 people
- Sponsor
- Joint Academy
Knee Osteoarthritis
Gait Modification Treatment for Knee Osteoarthritis
Knee osteoarthritis (OA) is a costly health condition affecting more than 10% of Canadian adults. Excessive and unbalanced loads passing through the knee joint have been implicated in the progression of OA.
- Trial name
- NCT02019108
- Testing
- Progressive walking program with toe-out gait modification, Progressive walking program
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- University of British Columbia
Bipolar Disorder
Using Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Bipolar Depression
The purpose of this study is to evaluate whether repetitive transcranial magnetic stimulation (rTMS) treatment is an effective adjunct treatment to mood stabilizers and Bupropion.
- Trial name
- NCT01583023
- Testing
- Bupropion, Active Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Osteoarthritis
A Study to Assess the Safety and Efficacy of an Investigational Drug in Patients With Osteoarthritis (0663-071)(COMPLETED)
This study was conducted to assess the safety and tolerability of the drug and to evaluate its efficacy in the treatment of osteoarthritis of the hip or knee in men and women.
- Trial name
- NCT00269191
- Testing
- MK0663, etoricoxib / Duration of Treatment 12 Weeks
- Volunteers
- 528 people
- Sponsor
- Organon and Co
Bone Scintigraphy and Knee Arthroplasty
Bone Scintigraphy and Unicompartimental Knee Arthroplasty
Study the potential interest of bone scintigraphy for patients undergoing unicompartmental knee arthroplasty
- Trial name
- PUC-INTEVO (NCT03145090)
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Brest
Knee Osteoarthritis
Internet Intervention to Improve Physical Activity in Early Knee Osteoarthritis
OPEN (Osteoarthritis Physical Activity and Exercise Net) is a website created based on a well developed behavioural theory. This intervention is developed for people with early knee osteoarthritis (OA) who have been sedentary.
- Trial name
- OPEN (NCT01608282)
- Testing
- OPEN website
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University of British Columbia
Arthropathy, Hip Arthropathy
Restoration Anatomic Acetabular Shell Revision Study
This study will be a non-randomized, ambidirectional (retrospective and prospective) study where all subjects will be followed prospectively.
- Conditions
- Arthropathy, Hip Arthropathy, Hip Osteoarthritis
- Trial name
- RAS (NCT05591859)
- Testing
- Restoration Anatomic Acetabular Shell
- Where
- United States
- Sponsor
- Stryker Orthopaedics
Arthritis, Osteoarthritis
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis…
- Conditions
- Arthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis Knee
- Trial name
- SOARPOC (NCT04956393)
- Testing
- Immediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hip Osteoarthritis, Leg Length Discrepancy
An Intelligent Instrument for Improved Leg Length and Hip Offset Accuracy in Total Hip Arthroplasty
Leg length discrepancies following total hip arthroplasty have been associated with nerve palsies, gait abnormalities, and lower back pain.
- Conditions
- Hip Osteoarthritis, Leg Length Discrepancy, Dislocation
- Trial name
- NCT02095093
- Testing
- Intellijoint HIP, Outrigger
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Pomegranate (P. Granatum) Peel Compress
The Effect of Pomegranate (Punica Granatum L.) Peel Compress Application on Pain and Physical Function Status
Osteoarthritis is the most common type of arthritis among rheumatologic diseases. Complementary therapies are one of the effective methods for pain control. This study was planned as a randomized controlled experimental study.
- Trial name
- Pomegranate (NCT06034106)
- Testing
- Pomegranate (Punica granatum) peel compress, Hot compress
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Arthritis
Sensitization in Osteoarthritic Knees
Musculoskeletal pains represent a major part of pain complaints in patients. Moreover, the treatment of musculoskeletal pain conditions by currently available drugs is not optimal (Curatolo and Bogduk 2001).
- Trial name
- NCT00379184
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis
A Double-Blind, Double Dummy, Randomized Comparison Study Of The Efficacy And Safety Of Valdecoxib 10mg Once Daily And Naproxen 500mg Twice Daily In Treating The Signs And Symptoms Of Osteoarthritis Of The Knee Or Hip In Taiwan
To evaluate the efficacy, safety, and tolerability of valdecoxib by comparing valdecoxib 10 mg daily (QD) with naproxen 500 mg twice daily (BID) in treating the signs and symptoms of osteoarthritis (OA) of the knee or hip.
- Trial name
- NCT00648258
- Testing
- valdecoxib, naproxen
- Where
- 4 sites in Taiwan
- Volunteers
- 130 people
- Sponsor
- Pfizer
Total Knee Arthroplasty, Osteoarthritis
Kinematic Analysis: Posterior Stabilized, Fixed Bearing Total Knee Arthroplasty With Attune Knee System
A better understanding of knee joint kinematics is important to explain the premature polyethylene wear failures within total knee arthroplasties (TKAs) and to help design a prosthesis that most closely approximates the normal…
- Trial name
- NCT02204748
- Testing
- DePuy Attune posterior stabilizing fixed bearing knee system
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- The University of Tennessee, Knoxville
Arthropathy of Hip Joint, Osteoarthritis, Hip
Opioid Free and Therapy Minimized Advantages Using HANA Table for Total Hip Arthroplasty
To prove that anterior approach total hip arthroplasty using the HANA table can be performed with little, if any, need for opioids using a combination of education, optimized pre op and post op pain protocols and optimized…
- Trial name
- NCT03790306
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- St. Elizabeth Medical Center, Utica, NY
Osteoarthritis
Investigating Medical Research Trends in Osteoarthritis Clinical Trials
Clinical research participation percentages haven't always been fully representative of a given demographic. The goal is to find out which aspects of a clinical trial may make it more difficult for patients to take part or see it…
- Trial name
- NCT05811858
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Back Pain, Osteoarthritis
Strategies for Prescribing Analgesics Comparative Effectiveness Trial
Chronic musculoskeletal pain conditions are among the most prevalent conditions in VA primary care. Over the past two decades, improved clinical attention to pain has been associated with exponentially greater use of long-term…
- Trial name
- SPACE (NCT01583985)
- Testing
- Opioid-intensive prescribing strategy, Opioid-avoidant prescribing strategy
- Where
- United States
- Volunteers
- 265 people
- Sponsor
- VA Office of Research and Development
Knee Osteoarthritis
Effectiveness of Blood Flow Restriction Exercise Therapy to Reduce Pain in Knee Osteoarthritis Patients
Resistance training of knee extensor muscles is being used in physiotherapy management in knee osteoarthritis (OA) to improve pain and physical function.
- Trial name
- BFR;OA (NCT04917952)
- Testing
- Blood Flow Restriction (BFR)
- Volunteers
- 42 people
- Sponsor
- University of West Attica
Osteoarthritis
Nurse Led Follow-up After Total Knee Arthroplasty
The aim of this study is to determine the effect of nurse led follow-up following total knee arthroplasty in regard to physical function, health related quality of life and self-efficacy.
- Trial name
- NFTKA (NCT01771315)
- Testing
- Telephone follow-up
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- University of Southern Denmark
Osteo Arthritis Knee
Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy for Patients With Knee Osteoarthritis
Osteoarthritis (OA) is the leading cause of disability in the United States. As osteoarthritis is associated with the lower limb muscle weakness, rehabilitation through quadriceps strengthening is a well-established treatment for…
- Trial name
- KneeBRIGHT (NCT04187092)
- Testing
- KneeBright Group, Standard Rehabilitation group
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Virginia
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