Clinical trials: Degenerative Joint Disease
Arthritis, Gout
Phone-Based Based Walk With Ease Program for Adults With Arthritis
The objective of this study is to examine the short-term (6-weeks and 6 months) and long-term (1 year) effects of a phone-based version of Walk With Ease intervention.
- Conditions
- Arthritis, Gout, Fibromyalgia, Rheumatoid Arthritis
- Trial name
- NCT05289544
- Testing
- Phone-Based Walk With Ease
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Hip Osteoarthritis
A Prospective Evaluation of the Cingal Injection for Hip Osteoarthritis
Osteoarthritis (OA) of the hip is one of the ten most disabling diseases in the developed world. Because OA gradually worsens over time, the sooner treatment is started, the more likely its impact is lessened.
- Trial name
- ECHO (NCT04084704)
- Testing
- Cingal
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Knee Osteoarthritis, Primary Total Knee Arthroplasty
Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.
The purpose of this study is to learn if using an Interspace between the Popliteal Artery and Capsule of the Knee (iPACK) injection technique (also called a "nerve block") that numbs the nerves going to the back part of the knee…
- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain
- Trial name
- NCT03353233
- Testing
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Osteoarthritis, Foot
A Comparative Trial of a Minimal-invasive Technique Versus Open Arthrodesis in the Treatment of Midfoot Arthritis
Group A: Patients suffering from midfoot arthritis after failed prior conservative therapy who undergo a reverse distal metatarsal minimal-invasive osteotomy Group B: Patients suffering from midfoot arthritis after failed prior…
- Conditions
- Osteoarthritis, Foot, Osteotomy
- Trial name
- NCT04894578
- Testing
- reverse distal metatarsal minimal-invasive osteotomy, tarsometatarsal fusion
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Kantonsspital Baden
Osteoarthritis, Knee
A Crossover Designed Study to Evaluate Effects of Microcurrent Therapy on Knee Osteoarthritis
This crossover designed study evaluates the effects of microcurrent therapy on knee osteoarthritis. Ín a previous study patients were randomized into four different groups.
- Trial name
- NCT03332914
- Testing
- Microcurrent therapy
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Knee Osteoarthritis
Stability of Uncemented Medially Stabilized TKA
Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship.
- Trial name
- NCT04017533
- Testing
- GMK Sphere TKR
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital
Osteoarthritis
Does Optimal Control of Pre-operative Chronic and Acute Pain Predict Improved Function After Orthopedic Surgery?
Despite the development of new pain medications, the prevalence of persistent postoperative pain (for more than three to six months) remains alarmingly high.
- Trial name
- NCT00581685
- Testing
- Pregabalin, Celecoxib
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Osteoarthritis Knees Both
Proprioception and BRACE Training in Knee Osteoarthritis
Knee osteoarthritis is common joint disorder in older adults. The prevalence of osteoarthritis is increasing in the elderly population and due to obesity.The aim of this study to compare improvement in balance between BRACE and…
- Trial name
- NCT04782167
- Testing
- BRACE, Propirioceptive training
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- khadija liaquat
Knee Osteoarthritis
Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA
This randomized, double-blind, controlled trial is designed to compare the analgesic efficacy and safety of perineural dexamethasone versus perineural dexmedetomidine as adjuvants to ropivacaine for ultrasound-guided interspace…
- Trial name
- NCT07386600
- Testing
- Ropivacaine 0.2% Injectable Solution, Dexamethasone 4mg, Dexmedetomidine
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Poznan University of Medical Sciences
Satisfaction
Prospective Trial of the TriFit™ Web Knee Brace
This is a prospective trial comparing improvements in pain, function, and quality of life in patients with early-stage knee osteoarthritis conservatively managed with the TriFit™ Web Knee Brace.
- Trial name
- NCT03633071
- Testing
- Web-knee brace
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
Osteoarthritis
Open-label Safety Extension Study of Gevokizumab in Erosive Osteoarthritis of the Hand
The purpose of this study is to evaluate the long-term safety of gevokizumab in the treatment of active inflammatory, erosive osteoarthritis of the hand.
- Trial name
- NCT02293564
- Testing
- gevokizumab
- Where
- 28 sites in United States
- Volunteers
- 312 people
- Sponsor
- XOMA (US) LLC
Osteoarthritis, Knee, Aging Problems
OKV Versus CKC for Biomechanics and Function in Mild Knee OA Patients
Background: Clinical recommendations suggest exercises as the core treatment for knee osteoarthritis (OA) patients. However, the biomechanical modification following exercise therapy and its influence on pain remains unclear.
- Trial name
- NCT04678609
- Testing
- Exercise
- Where
- Malaysia
- Volunteers
- 66 people
- Sponsor
- Universiti Sains Malaysia
Knee Osteoarthritis (OA), Joint Diseases
Remote Rehabilitation With Knee Brace for Individuals With Degenerative Joint Disease
The goal of this observational study is to learn how well remote rehabilitation and offloading the inner part of the knee joint using a custom-made knee brace work as non-surgical treatments for people with unicompartmental knee…
- Conditions
- Knee Osteoarthritis (OA), Joint Diseases, Knee Brace
- Trial name
- JC3D (NCT07188493)
- Where
- Poland
- Volunteers
- 36 people
- Sponsor
- MDH sp. z o.o.
Osteoarthritis, Knee
Gait Modifications and Cutaneous Stimulation
The purpose of this study is to quantify differences in joint mechanics between different types of walking in healthy individuals and individuals with knee pathology.
- Trial name
- NCT02884414
- Testing
- Cutaneous stimulation
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Stanford University
Knee Osteoarthritis, Total Knee Arthroplasty
Improvement of Total Knee Arthroplasty Effectiveness Using Preoperative Prehabilitation
Total knee arthroplasty (TKA) is the most effective treatment for stage III-IV knee osteoarthritis (OA). However, up to 30% of patients remain dissatisfied due to periarticular functional insufficiency, pain, and movement…
- Trial name
- TKA-PREHAB (NCT07790146)
- Testing
- Multimodal phenotype-based prehabilitation
- Where
- Russia
- Volunteers
- 64 people
- Sponsor
- Samara State Medical University
Hand Osteoarthritis
Outcomes After First-line Treatment of Hand Osteoarthritis
This study will investigate outcomes of a 3-month first-line treatment program for hand osteoarthritis, using data from the Swedish Osteoarthritis Registry.
- Trial name
- NCT07708454
- Testing
- 3 months of exercise and education
- Volunteers
- 2,000 people
- Sponsor
- Lund University
Osteoarthritis, Knee
Mechanically or Kinematically Aligned Total Knee Prosthesis
The mechanical alignment technique (Mechanical Alignment - MA) of a total knee prosthesis (TKA) was developed with the aim of making the installation of a TKA simple and reproducible, and that the prosthetic biomechanics are…
- Trial name
- BIOMAKA (NCT06158646)
- Testing
- kinematic knee prosthesis, biomechanic knee prosthesis
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Osteoarthrosis, ERAS
Nursing Intervention for the Reduction of Anxiety During the Process of Primary Total Hip Arthroplasty Within the Optimized Recovery Program.
Osteoarthrosis (OA) is a chronic, degenerative disease characterized by joint wear and tear. It is a major cause of pain, disability and decreased quality of life.
- Conditions
- Osteoarthrosis, ERAS, Anxiety, Nurse
- Trial name
- NIRARATC (NCT05882227)
- Testing
- video, Traditional information
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Barcelona
Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty Biomechanics
In total knee arthroplasty (TKA), the relationship between implant design, soft tissue balance, neuromuscular contributions, and rehabilitation strategies on patient satisfaction and functional outcomes is highly complex and…
- Trial name
- NCT03671954
- Testing
- Home Strengthening Exercises, Standard Physical Therapy, Preoperative Assessments
- Where
- 4 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Florida
Osteoarthritis of the Knee
Apitox, Honeybee Venom Treatment for Osteoarthritis Pain and Inflammation
The study will evaluate Apitox, pure honeybee venom as a treatment for pain and inflammation of osteoarthritis of the knee.
- Trial name
- HBV (NCT00949754)
- Testing
- honeybee venom (Apitoxin (Korea) Apitox (USA))
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Apimeds, Inc.
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