Clinical trials: Degenerative Joint Disease
Osteoarthritis, Hip
Comparison of Two Cementing Techniques of the Femoral Component in a Hip Prosthesis
The primary aim of the study is to compare migration of the cemented Corail stem representing polished surfaced versions of the femoral stem.
- Trial name
- NCT01952067
- Testing
- line-to-line reaming and cementing technique, standard over-reaming with 2 broach sizes
- Where
- Norway
- Volunteers
- 48 people
- Sponsor
- Norwegian University of Science and Technology
Knee Osteoarthritis
Effects of Textured Insoles on Balance, Physical Performance, and Plantar Pressure in Older Adults With Knee Osteoarthritis
This study aims to investigate the effects of textured insoles on balance, physical performance, and plantar pressure distribution in older adults with medial compartment knee osteoarthritis.
- Trial name
- TIKOA (NCT07097649)
- Testing
- Textured lateral wedge insole, Use of lateral wedge flat insole
- Volunteers
- 44 people
- Sponsor
- Esra Nur Turkmen
Thumb Osteoarthritis
Artificial Intelligence in Trapeziometacarpal Joint Osteoarthritis: Improving Assessment and Clinical Decision-Making
This is a retrospective cohort study utilizing radiographic and computed tomography (CT) imaging data collected during routine clinical care at Schulthess Klinik Zürich.
- Trial name
- TMCAI (NCT07148349)
- Testing
- No Intervention: Observational Cohort
- Where
- Switzerland
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Gonarthrosis, Antioxidative Stress
Effects of Physical Therapy on Oxidative Stress in Female Patients With Gonarthrosis
This study aimed to investigate the production of reactive oxygen derivatives (ROS) and reactive nitrogen derivatives (RNT) in female patients with knee OA, and their effects on oxidative stress by evaluating before and after…
- Trial name
- NCT05731011
- Testing
- antioxidative stress, electrotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Baskent University
Osteoarthritis
Safety and Efficacy of Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Osteoarthritis Pain
The objective of this study is to demonstrate the effectiveness and tolerability of the buprenorphine transdermal system (20 mg) in comparison to the buprenorphine transdermal system (5 mg) and oxycodone immediate release in…
- Trial name
- NCT00312221
- Testing
- Buprenorphine, oxycodone immediate-release
- Where
- 23 sites in United States
- Volunteers
- 418 people
- Sponsor
- Purdue Pharma LP
Knee Osteoarthritis, Arthritis
Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement
Total knee Arthroplasty (TKA) is a highly effective treatment for knee osteoarthritis. Mid- to long-term follow-up studies have shown good clinical outcomes following TKA; despite these results, there is a high incidence of…
- Conditions
- Knee Osteoarthritis, Arthritis, Surgery
- Trial name
- NCT04192006
- Testing
- Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
Osteoarthritis
Oral Nutritional Optimization in Total Joint Arthroplasty
The purpose of this study is to determine the effect on hematological markers of nutritional intervention on nutritionally deficient patients following total joint replacement surgery.
- Trial name
- NCT04210284
- Testing
- Ensure
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- NYU Langone Health
Osteoarthritis, Knee
Predictive Values for the Outcome of Genicular Nerve Radiofrequency Ablation for Chronic Knee Pain
Researchers are trying to assess a predictive value or correlation between patient and procedural characteristics and outcome measures results after genicular nerve radiofrequency ablation.
- Trial name
- NCT05222776
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people
- Sponsor
- Diskapi Teaching and Research Hospital
Osteoarthritis
The Impact of Total Knee Arthroplasty Surgical Technique on Coronal Plane Motion and PatelloFemoral Articulation
The purpose of this study is to examine the impact of two surgical techniques on the outcome of the knee replacement surgery.
- Trial name
- NCT01855906
- Testing
- Gap balanced surgical technique, Measured resection
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Knee Osteoarthritis
Robotic Assisted vs Custom Made Total Knee Arthroplasty
The goal of this clinical trial is to compare Robotic Assisted, functionally aligned vs Custom Made Total Knee Arthroplasty in patients with knee osteoarthritis.
- Trial name
- Knieathlon (NCT06280352)
- Testing
- Custom made Total Knee Arthroplasty, Functionally aligned robotically assisted total knee arthroplasty
- Where
- 2 sites in Austria
- Volunteers
- 120 people
- Sponsor
- Austrian Workers Compensation Board Styria
Osteoarthritis
Efficacy and Safety of Oral Salmon Calcitonin in Patients With Knee Osteoarthritis (OA 2 Study)
The purpose of this phase III study is to Evaluate the Efficacy and Safety of Oral Salmon Calcitonin in the Treatment of Patients with Osteoarthritis of the Knee
- Trial name
- NCT00704847
- Testing
- Oral Salmon Calcitonin
- Where
- 18 sites in United States, Belgium and 8 more
- Volunteers
- 1,030 people
- Sponsor
- Nordic Bioscience A/S
Hip Osteoarthritis, Hip Arthropathy
Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty
Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for hip arthroplasty
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Hip Pain Chronic
- Trial name
- NCT06233604
- Testing
- 0.9%sodium chloride, Dexamethasone, Dexmedetomidine
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis of Knee
The Recovery Time of Quadriceps Strength After Total Knee Arthroplasty (TKA): The Effect of Quadriceps Incision Length
Minimally invasive total knee arthroplasty (MIS-TKA) became the popular technique. It had the less postoperative pain and shorter recovery time compared to the conventional technique.
- Trial name
- NCT01450904
- Testing
- Quadriceps incision < 2 cm, Quadriceps incision 2-4 cm, Quadriceps incision > 4 cm
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Osteoarthritis, Overweight and Obesity
Effects of an Online Training Program for Physiotherapists About Weight Management for People With Osteoarthritis
A randomized controlled trial for which the primary objective is to evaluate the effects of an online training program on physiotherapist's self-reported confidence in knowledge about weight management for people with…
- Trial name
- NCT04574804
- Testing
- Online training program in weight management for osteoarthritis
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Knee Osteoarthritis
Multimodal Evaluation of Cartilage Lesions of Patellofemoral Joint
Evaluation and comparison of histological analysis, 9,4 tesla MRI, Full-Field Optical Coherence Tomography (FFOCT) and ultrasound-based navigation system for cartilage degeneration analysis of patellofemoral joint.
- Trial name
- MULTICART (NCT03210584)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Grenoble
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System
This is a post-marketing surveillance on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT03547947
- Testing
- Medacta Shoulder System
- Where
- 6 sites in France, Germany and 1 more
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Osteoarthritis
Comparison of Quadriceps-sparing Minimally Invasive and Medial Parapatellar Total Knee Arthroplasty
Quadriceps-sparing minimally invasive total knee arthroplasty (TKA) with side-cutting instruments has been proposed to limit surgical dissection without compromising the surgical outcome.
- Trial name
- NCT01160835
- Testing
- total knee arthroplastyinstruments
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Knee Osteoarthritis, Knee Arthroplasty
Quadriceps Sparing Versus Standard Total Knee Arthroplasty
This study is a randomized clinical trial comparing standard medial para-patellar total knee arthroplasty with a quadriceps sparing mid-vastus approach.
- Trial name
- NCT03081663
- Testing
- Quads-Sparing Approach, Medial Para-Patellar Approach
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis
Complex Āyurvedic Treatment in Osteoarthritis of the Knee Compared to Standard Care.
The aim of this study is to evaluate the effectiveness of a complex āyurvedic diagnosis and treatment compared to conventional standard care in patients with OA of the knee.
- Trial name
- CARAKA (NCT01225133)
- Testing
- Complex Ayurvedic Treatment, Conventional Care
- Where
- 2 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Charite University, Berlin, Germany
Knee Arthroplasty, Total, Robotic-assisted
RObotic-assisted Versus Conventional Knee Endoprosthetic Techniques
Rationale for conducting the study: The ROCKET study evaluates the clinical and economic outcomes of robot-assisted total knee arthroplasty (RTKR) compared with conventional total knee arthroplasty (TKR).
- Conditions
- Knee Arthroplasty, Total, Robotic-assisted, Osteoarthritis of the Knee
- Trial name
- ROCKETS (NCT06389435)
- Testing
- Robot-assisted total knee arthroplasty, Conventional total knee arthroplasty
- Where
- 2 sites in Sweden
- Volunteers
- 1,600 people
- Sponsor
- Danderyd Hospital
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