Clinical trials: Degenerative Osteoarthritis
Osteoarthritis
Safety and Feasibility Study of Autologous Stromal Vascular Fraction (SVF) Cells for Treatment of Osteoarthritis
Autologous stromal vascular fraction (SVF) injected into joints of 20 patients with grade 2, 3, or 4 radiographic OA severity will be safe and feasible as assessed by lack of treatment associated adverse events.
- Trial name
- NCT01885832
- Testing
- Autologous adipose tissue stromal vascular fraction
- Where
- Panama
- Sponsor
- Translational Biosciences
Hand Osteoarthritis
Happy Hands E-self-management Pilot Study
This pilot study will assess usability of a e-self-management program for patients with hand osteoarthritis through the Happy Hands app. People with hand osteoarthritis will be recruited for the study.
- Trial name
- NCT05150171
- Testing
- e-self-management intervention
- Where
- 2 sites in Norway
- Volunteers
- 72 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis, Knee
Safety & Efficacy FloGraft (Micronized Human Amnion Chorion Membrane)® in Adults With Pain Due to OA of the Knee
Safety \& Efficacy of FloGraft (Micronized Human Amnion Chorion Membrane)® in Adults With Pain Due to Osteoarthritis of the Knee.
- Trial name
- OA (NCT03441607)
- Testing
- mHACMb
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Applied Biologics, LLC
Degenerative Joint Disease of Knee, Osteoarthritis
A Randomized Controlled Trial for Partial Knee Arthroplasty
This is a prospective, multi-center, two-arm, randomized, controlled post-market study to evaluate and compare the clinical accuracy of component placement in robotic-assisted UKA and that of traditional methods.
- Conditions
- Degenerative Joint Disease of Knee, Osteoarthritis, Traumatic Arthritis, Varus Deformity
- Trial name
- NCT05037734
- Testing
- Persona Partial Knee System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Knee Osteoarthritis
Bone Marrow Aspirate Compared to Platelet Rich Plasma for Treating Knee Osteoarthritis
This study is intended to compare whether bone marrow aspirate concentrate or platelet rich plasma injections is more effective in treating knee osteoarthritis.
- Trial name
- EmCyte (NCT03289416)
- Testing
- Pure PRP II, PureBMC
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Andrews Research & Education Foundation
Arthroplasty, Replacement, Hip
A Post Market Clinical Follow-up Study With the aneXys Cup
The purpose of the study is the evaluation of the clinical and radiological short- to long-term safety and performance of the aneXys cup. The data will be used for an ongoing evaluation of the product safety and performance.
- Trial name
- NCT03274830
- Testing
- aneXys
- Where
- 3 sites in Germany
- Volunteers
- 102 people
- Sponsor
- Mathys Ltd Bettlach
Osteoarthritis
A Prospective Total Joint Surgery Registry to Monitor Short- and Long-Term Clinical Outcomes
The investigators propose a prospective longitudinal registry study to collect and compare preoperative and postoperative information from patients who undergo total joint arthroplasty (TJA).
- Trial name
- NCT06687109
- Testing
- Total Knee Arthroplasty, Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Spokane Joint Replacement Center
Osteoarthrosis
Bimetric-10: Investigation of Patients Who Have Underwent Total Hip Arthroplasty With a Cemented Bi-Metric Stem
This is a 10 year follow-up investigation of patients who have underwent total hip arthroplasty with a cemented Bimetric stem.
- Trial name
- NCT00192699
- Testing
- Bimetric femoral stem
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Knee Osteoarthritis
Effect of Retrowalking Program Versus Whole Body Vibration in Patients With Chronic Knee Osteoarthritis
Osteoarthritis is one of the most common degenerative joint disease that affects approximately more than 300 million people worldwide
- Trial name
- NCT06110104
- Testing
- routine physiotherapy program for knee osteoarthritis, Retro-walking program, whole body vibration training
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marwa Gamal Abd El Ghany Fathalla
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Tinnitus, Temporomandibular Joint Disorders
CBCT and Audiological Analysis of the TMJ-Tinnitus Relationship
The aim of this study is to investigate the relationship between Temporomandibular Disorders (TMD) and subjective tinnitus at both morphological and functional levels.
- Conditions
- Tinnitus, Temporomandibular Joint Disorders, Somatosensory Tinnitus, Osteoarthritis, Temporomandibular Joint
- Trial name
- NCT07460193
- Testing
- Cone Beam Computed Tomography (CBCT), Audiological Assessment, Clinical TMJ Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kutahya Health Sciences University
Knee Osteoarthritis, HA Injection
Analyzing Composition and Lubrication Properties of Synovial Fluid
To analyze the relationship between composition of synovial fluid and its lubrication properties
- Conditions
- Knee Osteoarthritis, HA Injection, One Injection Per Week for Five Week, Synovial Fluid Composition
- Trial name
- SFCL (NCT00912106)
- Testing
- Synovial fluid composition and lubrication analysis
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- Far Eastern Memorial Hospital
Obesity, Osteoarthritis
Surgical Weight-Loss to Improve Functional Status Trajectories Following Total Knee Arthroplasty (SWIFT Trial)
The purpose of the SWIFT Trial is to answer two research questions. 1. Does bariatric surgery before total knee arthroplasty (TKA) improve both perioperative and long-term outcomes of TKA in extreme obesity? 2.
- Trial name
- SWIFT (NCT02598531)
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Geisinger Clinic
Osteoarthritis, Knee
The Inclination of the Proximal Tibiofibular Joint Surface and Medial Compartment Knee Osteoarthritis
This study aims to research on the association between the inclination of the proximal tibiofibular joint surface and medial compartment knee osteoarthritis.
- Trial name
- NCT03147495
- Testing
- Standing anteroposterior knee radiographs and special proximal tibiofibular joint radiograph.
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- 113th Hospital of Chinese People's Liberation Army
Osteoarthritis
A Study of Duloxetine in Participants With Chronic Pain Due to Osteoarthritis in China
The purpose of this study is to assess the efficacy and safety of duloxetine once daily compared with placebo on the reduction of pain due to osteoarthritis (OA) in knee or hip in participants in China.
- Trial name
- NCT01931475
- Testing
- Duloxetine
- Where
- 12 sites in China
- Volunteers
- 407 people
- Sponsor
- Eli Lilly and Company
Osteoarthritis of the Knee
Structured Non-operative Treatment of Knee Osteoarthritis
The purpose of this study is to test whether an algorithm for systematic non-surgical treatment consisting of corrective insoles, neuromuscular training, weight loss, patient education and pharmacological treatment with…
- Trial name
- NCT01535001
- Testing
- Neuromuscular training (NEMEX-TJR), Information, Paracetamol
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Knee Osteoarthritis
The Effect of Theory-driven Physiotherapy on Physical Activity in Knee OA.
Knee osteoarthritis (OA) is a leading cause of pain, disability, and reduced physical functioning worldwide. Although physiotherapy and physical activity are recommended as first-line treatments, many individuals with knee OA do…
- Trial name
- EXPLOR (NCT07901881)
- Testing
- EXPLOR-3
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Mark van Loo
Osteoarthritis, Avascular Necrosis
Arcos Revision Stem: Evaluation of Clinical Performance
The primary purpose of this study is to evaluate the clinical performance of the Arcos Revision Stem system, determine the stability of the implants, and evaluate any relationship between Paprosky bone defect level and the…
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Deformity
- Trial name
- NCT01820611
- Testing
- Arcos Revision Stem System
- Where
- 5 sites in Finland, Spain and 2 more
- Volunteers
- 74 people
- Sponsor
- Zimmer Biomet
Diabetes Mellitus, Steroid Diabetes
Effect of Corticosteroid Injections on Blood Glucose
The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee and hip joints in diabetic patients on resultant blood glucose readings.
- Conditions
- Diabetes Mellitus, Steroid Diabetes, Shoulder Osteoarthritis, Knee Osteoarthritis
- Trial name
- CSI (NCT05048264)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
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