Clinical trials: Degenerative Osteoarthritis
Osteoarthritis, Hip
Metal-metal Articulations Versus Standard 28 mm Cementless Total Hip Arthroplasty
Younger hip patients often need revision of their hip replacement due to wear and loosening. Newer concepts (resurfacing and large head total hip replacement) with articulation surfaces in metal may reduce the wear, increase the…
- Trial name
- NCT01113762
- Testing
- articular surface replacement ASR, DePuy, ReCap/Magnum modular head, Biomet, Bimetric stem, mallory/head cup, 28 mm ceramic head, Biomet
- Where
- 2 sites in Denmark
- Volunteers
- 71 people
- Sponsor
- University of Southern Denmark
Bilateral Knee Osteoarthritis
Gait, Stair Climbing and Postural Stability in Knee Osteoarthritis Patients After Hyaluronic Acid Injection
Treatment: five intro-articular Hyaluronic Acid injection Assessment has two parts, that are as follow: 1. Postural stability and risk of fall assessment using Biodex stability index and "Timed up and Go" test 2.
- Trial name
- NCT02063373
- Testing
- Hyaluronic acid
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Non-inflammatory Joint Diseases
Metal on Metal Versus Ceramic on Metal Hip Replacement
The purpose of this study is to compare the performance of artificial hips with metal heads and metal sockets to artificial hips with ceramic heads articulating with metal socket components.
- Trial name
- NCT00208494
- Testing
- Total Hip Replacement
- Where
- 9 sites in United States, Canada
- Volunteers
- 392 people
- Sponsor
- DePuy Orthopaedics
Degenerative Joint Disease of the Hip
A Prospective, Multicenter, Single Arm Feasibility Study of the Safety and Performance of GRADION™ Hip Total Cartilage Replacement (TCR)™ in the Treatment of Degenerative Joint Disease of the Hip
This is a prospective, multicenter, single arm feasibility study of the safety and performance of the GRADION™ Hip Total Cartilage Replacement (TCR)™ in patients who require cartilage replacement.
- Trial name
- NCT01982266
- Testing
- GRADION™ Hip Total Cartilage Replacement (TCR)™
- Where
- Netherlands
- Volunteers
- 4 people
- Sponsor
- Biomimedica, Inc
Knee Osteoarthritis
Effectiveness of Two Hyaluronic Acids in Osteoarthritis of the Knee
The purpose of this study is to assess whether a single injection hyaluronic acid (HA) product is not inferior to a 3 injection HA product at 24 weeks (6 months), in terms of effectiveness in reducing pain when walking in…
- Trial name
- NCT01543737
- Testing
- 3ml hyaluronic acid (DUROLANE), 2ml hyaluronic acid, (HYALGAN)
- Where
- 17 sites in France, Monaco
- Volunteers
- 290 people
- Sponsor
- Bioventus LLC
Osteoarthritis, Knee
Evaluation of the TruMatch® System in Knee Prosthetic Surgery
Patient specific instrumentation is an alternative to conventional intra- and extra-medullary guides to perform the femoral and tibial cuts in total knee replacement (TKR).
- Trial name
- NCT01876654
- Testing
- TruMatch® patient specific cutting guide
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Milan
Osteoarthritis
Etude 3000 ARTHROSES Symptomatic Knee and Hip Osteoarthritis Prevalence Survey
Nationwide descriptive epidemiology survey aiming to determine lower limb OA prevalence, based on a validated method previously used to assess inflammatory rheumatism (rheumatoid arthritis and spondylarthropathy) prevalence in…
- Trial name
- 3000ARTHROSE (NCT01400529)
- Where
- 6 sites in France
- Volunteers
- 3,000 people
- Sponsor
- Central Hospital, Nancy, France
Thumb Osteoarthritis, Pain
Laser Therapy, Pain and Carpometacarpal Joint Osteoarthritis Treatment
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Conditions
- Thumb Osteoarthritis, Pain, Physical Disorder
- Trial name
- Laser (NCT03270488)
- Testing
- Laser
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- University of Malaga
Osteoarthritis, Hip
Clinical Investigation Comparing Two Different Ultra-porous Coated Surfaces of Uncemented Cups
A randomised controlled study comparing two types of ultra-porous coated uncemented cups in total hip arthroplasty. Primary objective is to investigate if the clinical, radiological and patient-reported outcome of the new…
- Trial name
- NCT05773261
- Testing
- MobilLINK TrabecuLINK cup, Pinnacle Gription cup
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Umeå University
Knee Osteoarthritis
Knee Osteoarthritis and Rehabilitation
Osteoarthritis (OA) is a chronic degenerative disease of articular cartilage that causes hypertrophic changes in bone. OA is a non-inflammatory progressive musculoskeletal disease and is one of the most common degenerative…
- Trial name
- NCT06432842
- Testing
- Laser Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Hip Osteoarthritis, Hip Arthropathy
The Pericapsular Nerve Block in Total Hip Arthroplasty
In order to continue progressing towards outpatient total hip arthroplasty (THA), methods to adequately manage postoperative pain is of paramount importance.
- Trial name
- PENG (NCT04729686)
- Testing
- Pericapsular Nerve Block, Fascia Iliaca Nerve Block
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- LifeBridge Health
Chronic Knee Pain
Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)
This study aims to determine analgesic and anti-inflammatory effects of dual-wavelength PBM in people with symptomatic knee OA.
- Trial name
- EPIC-KO (NCT07079969)
- Testing
- Photobiomodulation therapy (PBM) device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Consent Forms, Osteoarthritis, Knee
Development, Piloting and Evaluation of an Evidence-based Informed Consent Form for Total Knee Arthroplasty
Every medical intervention requires informed consent. Informed consent may include comprehensible information about the necessity and kind of the intervention, material risks and consequences or alternative treatments.
- Conditions
- Consent Forms, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- EvAb-Pilot (NCT04669483)
- Testing
- evidence-based informed consent form
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- University of Witten/Herdecke
Knee Osteoarthritis, Knee Pain Chronic
Dorsal Root Ganglion Stimulation for the Treatment of Arthritic Knee Pain
Dorsal root ganglion stimulation (DRG-S) may be able to treat mechanical pain caused by tissue injury or damage such as trauma or arthritis in addition to pain caused by nerve dysfunction or injury.
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis, Knee Arthropathy
- Trial name
- NCT05103527
- Testing
- Dorsal Root Ganglion Stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kenneth B Chapman
Osteoarthritis
Efficacy and Safety of Intraarticular Injections of Hyalgan in the Treatment of Osteoarthritis of the Knee
Evaluate the efficacy and safety of Hyalgan, at a dose of 20mg/2ml administered as 5 intraarticular injections at weekly intervals, for the sustained relief of pain and amelioration of joint dysfunction in patients of OA of the…
- Trial name
- NCT01319461
- Testing
- Hyalgan, sterile normal saline
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Med Pharma Co., Ltd.
Knee Osteoarthritis
Effectiveness of a Knee Brace When Combined With Viscosupplementation in the Treatment of Knee Osteoarthritis
Hypothesis: Viscosupplementation when combined with an off-loading knee brace is more effective in treating the symptoms of knee OA then treating with viscosupplementation alone
- Trial name
- NCT01478386
- Testing
- Orthovisc, DonJoy HA lite knee brace, Orthovisc injections and DonJoy HA lite knee brace
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- OAD Orthopaedics
Knee Osteoarthritis
Knee Pain Phenotypes in the Community Study
The focus of the study is to determine the prevalence and variance of self-reported knee pain characteristics in a community-derived sample of adults aged 40 years and over.
- Trial name
- NCT02098070
- Where
- United Kingdom
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Osteoarthritis
Effects of Isometric Versus Isotonic Exercise in Female Patients With Osteoarthritis
to find out the Effects of Isometric Versus Isotonic Exercise in Female Patients With Osteoarthritis
- Trial name
- NCT05873088
- Testing
- Isometric, Isotonic Exercise
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Superior University
Knee Osteoarthritis
Clinical Evaluation of the Levitation Knee Brace
Osteoarthritis (OA) is a debilitating disease affecting approximately 1/3 of Canadians over the age of 25. Knee OA typically involves at least 2 of 3 compartments in the knee joint.
- Trial name
- NCT05543486
- Testing
- Levitation 2 Tri-Compartment Offloader (TCO) knee brace, Knee sleeve
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of Calgary
Osteoarthritis of Hip
ArCom® and ArComXL® Polyethylene Data Collection
The purpose of this prospective clinical data-collection is to document the performance, clinical outcomes, and wear rates of ArCom® and ArComXL® Polyethylene.
- Trial name
- NCT00565786
- Testing
- ArCom® Polyethylene, ArComXL® Polyethylene
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Zimmer Biomet
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