Clinical trials: Degenerative Osteoarthritis
Radiofrequency, Alcohol
Radiofrequency Applications and Alcoholic Neurolysis of Genicular Nerve for the Treatment of Knee Osteoarthritic Pain
This study aims to investigate the efficacy of radiofrequency ablation and alcoholic neurolysis of genicular nerve on alleviating pain and improving the function of advanced knee osteoarthritis patients.
- Conditions
- Radiofrequency, Alcohol, Genicular Nerve, Knee Osteoarthritis
- Trial name
- NCT06520384
- Testing
- Radiofrequency, Alcohol 30%, Alcohol 50%
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Osteoarthritis, Knee
Radial Versus Focused Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis
Radial versus Focused Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis : A Randomized Control Trial
- Trial name
- NCT03921749
- Testing
- Shockwave
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Mackay Memorial Hospital
Osteoarthritis, Degenerative Joint Disease
Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement
The purpose of this study is to clarify the efficacy of a multidrug versus single drug periarticular injection when only standard operative and postoperative pain management protocols used and the control group is exposed to what…
- Trial name
- NCT03119038
- Testing
- Bupivicaine + epinephrine, Bupivacaine, Ropivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteoarthritis, Knee
The Effects of Intra-articular Platelet-Rich Plasma Injection on The Severity of Knee Osteoarthritis
This is a single-center, randomized control trial The aim of this study is to compare PRP with placebo as the treatment of knee OA Conducted at Puri Raharja Hospital Bali in January-June 2022 Sample consisted of 106 patients with…
- Trial name
- NCT05722626
- Testing
- PRP, Normal Saline
- Where
- Indonesia
- Volunteers
- 106 people
- Sponsor
- Universitas Bali Internasional
Osteo Arthritis Knee and Hip
Predicting The Right Advice at The Right Time in Patients With Hip and Knee OsteoArthritis: the e-cOAch Cross-over.
This study aims to learn how symptoms and daily functioning change over time in people with hip or knee osteoarthritis (OA). The goal is to use this information to build computer models that can predict these changes.
- Trial name
- e-cOAch (NCT07423858)
- Testing
- Physical Activity program, Sleep program, Weight management program
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- UMC Utrecht
Osteoarthritis, Degenerative Joint Disease
Post Marketing Clinical Follow up Study to Evaluate the Performance and Safety of HYALEXO
This trial is a post marketing clinical follow up study, aiming to evaluate the performance and safety of Hyalexo for pain relief in patients suffering from osteoarthritis or degenerative joint diseases.
- Trial name
- NCT05229458
- Volunteers
- 54 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Independence, Hemiplegia
Turkish Validation and Reliability of the John Hopkins In-Room Independence Scale
The aim was to conduct a Turkish validity and reliability study of the Johns Hopkins In-Room Independence Scale. The investigators believe this scale will address the lack of information regarding fall risk and dependency…
- Conditions
- Independence, Hemiplegia, Paraplegia, Parkinson Disease
- Trial name
- NCT07250243
- Testing
- In-room independence assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Obesity
Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis
This study will look at participants body weight from the start to the end of the study. It will also look at how much pain participants have in participants knee from the start to the end of the study and how this affects…
- Trial name
- NCT05064735
- Testing
- semaglutide 2.4 mg
- Where
- 122 sites in United States, Canada and 9 more
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Symptomatic Hip Osteoarthritis
The Efficacy Study of Sodium Hyaluronate to Treat Symptomatic Hip Osteoarthritis
To demonstrate the difference in terms of symptomatic efficacy between ADANT® sodium hyaluronate and placebo following an intra-articular injection in patients with symptomatic osteoarthritis of the hip.
- Trial name
- NCT00330135
- Testing
- Sodium hyaluronate
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Daiichi Sankyo
Arthritis
Evaluation of Walk With Ease in Arthritis
The overall goal of this study is to determine the whether the Walk with Ease (WWE) program in its 2 version (group-assisted and self-directed) can increase physical activity and fitness levels among individuals (18 years and…
- Trial name
- WWE (NCT00526435)
- Testing
- Walk with Ease - Group, Walk with Ease - Self
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- Centers for Disease Control and Prevention
Knee Osteoarthritis
Symptomatic Efficacy of Diacerein in Knee Osteoarthritis
Pain is the main symptom of osteoarthritis that motivates medical visits. Diacerhein has already demonstrated its efficacy in knee and/or hip osteoarthritis.
- Trial name
- NCT00445276
- Testing
- Diacerein
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Laboratoires NEGMA
Knee Osteoarthritis
iUni G2+ Prospective Study
This study is designed to monitor long term clinical outcomes of the iUni G2+ unicompartmental knee replacement
- Trial name
- NCT01820676
- Testing
- iUni G2+
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Restor3D
Osteoarthritis, Knee
NEO6860, a TRPV1 Antagonist, First in Human Study
This study is a double blind, placebo controlled, ascending single and multiple oral dose study conducted in two parts, aimed at determining the safety and tolerability of single and multiple oral doses of NEO6860 in healthy…
- Trial name
- NCT02337543
- Testing
- NEO6860
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Neomed Institute
Wrist Osteoarthritis
PRC With Meniscal Allograft Arthroplasty for Wrist Osteoarthritis
This study plans to learn more about the effect of adding tissue graft for wrist osteoarthritis reconstruction procedures. Previous studies have shown better allograft stability, and no documented foreign body reaction than with…
- Trial name
- NCT05412615
- Testing
- Meniscus Allograft Transplantation with Proximal Row Carpectomy, Proximal Row Carpectomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Arthrosis, Traumatic Arthritis
The Medacta International SMS Post-Marketing Surveillance Study
This is a Post-Marketing Surveillance of SMS femoral stem prosthesis.
- Conditions
- Arthrosis, Traumatic Arthritis, Rheumatoid Polyarthritis, Congenital Hip Dysplasia
- Trial name
- NCT02748408
- Testing
- SMS femoral stem
- Where
- 4 sites in Austria, Italy and 2 more
- Volunteers
- 550 people
- Sponsor
- Medacta International SA
Osteoarthritis, Knee
Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the Knee
This study was performed to demonstrate that treatment with valdecoxib 10 mg daily (QD) was at least as effective as with naproxen 500 mg twice daily (BID), a standard non-steroidal anti-inflammatory drug (NSAID), when taken for…
- Trial name
- NCT00652808
- Testing
- valdecoxib, naproxen
- Where
- 8 sites in South Korea
- Volunteers
- 265 people
- Sponsor
- Pfizer
Osteoarthritis, Knee
Intraosseous With Intra-articular Injection of Platelet Rich Plasma in Treatment of Knee Osteoarthritis
The aim of this study was to compare the efficacy of treatment in three groups of patients with knee osteoarthritis (OA) given a combination of intraosseous with intra-articular injection of platelet rich plasma (PRP)…
- Trial name
- NCT03329235
- Testing
- PRP, HA
- Volunteers
- 86 people
- Sponsor
- Cangzhou Central Hospital
Osteoarthritis, Knee
Mobilizing Hispanics With Knee Osteoarthritis
The objective is to conduct an early-stage clinical trial in order to provide data required to support a future clinical trial to demonstrate the effectiveness of a culturally acceptable treatment program to increase exercise and…
- Trial name
- NCT06522906
- Testing
- Muscle Strengthening, General Physical Activity, Education
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Knee Osteoarthritis
Knee Osteoarthritis Treatment With Adipose-derived Stem Cells: Phase II Clinical Trial
In 1990, the prevalence of osteoarthritis of the hip or knee was very low 3.5% in Saudi Arabia, it increased to 53.3% and 60.9% in male in female patients respectively in 2002.
- Trial name
- NCT03308006
- Testing
- Stem cells
- Where
- Saudi Arabia
- Volunteers
- 18 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Osteoarthritis, Knee
Impact of Noninvasive Targeted Pulsed Electromagnetic Field (tPEMF) on Opioid Use, Pain, and Joint Function Following Total Knee Arthroplasty
The purpose of this study is to determine the effectiveness of pulsed radio frequency (PRF), a type of electromagnetic field treatment with the Ivivi Torino II for reducing post-operative narcotic use in patients recovering from…
- Trial name
- NCT01475604
- Testing
- Ivivi Torino II
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Amp Orthopedics, Inc.
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