Clinical trials: Degenerative Osteoarthritis
Osteoarthritis, Knee, Osteoarthritis, Hip
Active Video Games for Older Adults With Knee and/or Hip Osteoarthritis.
Population aging is currently an issue of primary relevance, constituting an enormous challenge for institutions and society. On the other hand, osteoarthritis (OA) is the most prevalent arthropathy in the elderly, strongly…
- Trial name
- NCT05839262
- Testing
- Conventional physical rehabilitation plus Active video games (CPR+AVG), Conventional physical rehabilitation alone (CPR)
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Cristian Alvarez
Osteoarthritis
A RCT of Supportive Finger Tape for PIPJ Osteoarthritis
Oesteoarthritis of the joints of the finger(s) is a common problem. The first-line treatment involves pain killers taken either as tablets, gels, or patches.
- Trial name
- NCT02220374
- Testing
- Supportive Finger Tape
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Mid Yorkshire Teaching NHS Trust
Osteoarthritis
Single-use Efficiency Instruments With Patient Specific Technique (MyKnee®) Versus Traditional Metal Instruments With Conventional Surgical Technique
To compare economic factors and the rate of adverse events between two types of instrumentation used for total knee replacement: Single-use Efficiency Instruments with Patient Specific Technique (MyKnee®) Traditional Metal…
- Trial name
- NCT03148379
- Testing
- Customized patient instruments, Traditional Metal Instruments
- Where
- 5 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Osteoarthritis
Cemented vs. Non-Cemented TSA for OA of the Shoulder
The purpose of the study is to investigate the fixation of the humeral component in total shoulder arthroplasty for primary osteoarthritis of the glenohumeral joint.Our hypothesis is that uncemented fixation of the humerus will…
- Trial name
- NCT00158418
- Testing
- Cemented Humeral Stem, Uncemented Humeral Stem
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Fowler Kennedy Sport Medicine Clinic
Knee Osteoarthritis
Effect of Energy Restriction and Exercise for Knee Osteoarthritis
The investigators are looking at the effects of energy restriction, with or without exercise on markers of inflammation in individuals with knee osteoarthritis.
- Trial name
- NCT05518890
- Testing
- Diet Only, Diet plus Exercise
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Bath
Osteoarthritis, Knee Joint Contractures
Creating a Tissue Bank of Knee Capsules
A contracture is a pathological condition limiting range and function of joints. Contractures of large and small joints alike will affect one's ability to independently perform daily activities such as eating, dressing or…
- Trial name
- NCT01320124
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Nonalcoholic Steatohepatitis, Osteoarthritis
FTIH Study of ECC0509 in Healthy Volunteers
A Phase 1, Single-Center, Randomized, Double-Blind, Placebo-Controlled, Single And Multiple Ascending Dose, First-Time-In-Human Study to Assess The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ECC0509 in…
- Trial name
- NCT05012423
- Testing
- ECC0509
- Where
- Australia
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Eccogene
Knee Osteoarthritis
The Effectiveness of Ultrasound Guided Ozone (O2-O3) Injection With Knee Osteoarthritis
Knee ostheoarthritis (KOA) is a common disabling and degenerative disease leading to painful joints, articular stiffness, and decreased function.
- Trial name
- NCT04830423
- Testing
- Medical ozone injection, steroid injection group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
the Treatment of Knee Osteoarthritis
Comparative Assessment of Intra-articular Knee Injections of Platelet-rich Plasma (PRP) and Hyaluronic Acid in the Treatment of Knee Osteoarthritis
The incidence of cartilage pathology has grown due to the ageing population, and the increase in sports participation and its associated trauma.
- Trial name
- NCT01697423
- Testing
- platelet-rich plasma, durolane
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Osteoarthritis of the Knee
Autograft Versus Calcium Phosphate Macroporous Bioceramics as Bone Substitute for Tibial Valgus Osteotomy
The aim of the study is to compare radiological behavior of blocks of macroporous phosphocalcium as bone substitute in comparison with iliac crest autograft in tibial valgus osteotomy.
- Trial name
- NCT00200603
- Testing
- calcium phosphate macroporous bioceramics
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
Mild to Moderate Knee OA
Effects of Intra-articular Hypertonic Dextrose and Hyaluronic Acid on Primary Knee Osteoarthritis.
The aim of this study is to compare the effectiveness of intra-articular hypertonic dextrose and hyaluronic acid in managing pain and improving function in patients with primary knee osteoarthritis (KOA).
- Trial name
- NCT07102225
- Testing
- prolotherapy solution of 20% dextrose, Hyaluronic Acid (HA)
- Where
- Bangladesh
- Volunteers
- 56 people
- Sponsor
- Bangladesh Medical University
Knee Osteoarthritis, Knee Pain Chronic
iPACK Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT06087562
- Testing
- Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL
- Where
- Poland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Knee
Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN
A previous multicenter trial led by Bioiberica S.A. has confirmed the efficacy and safety of DROGLICAN for the treatment of osteoarthritis (OA) in patients with severe pain.
- Trial name
- DRIP (NCT02821468)
- Testing
- Droglican, Paracetamol or oral NSAIDs excluding COX2 inhibitors
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Bioiberica
Osteoarthritis, Knee, Perfusion
Evaluation of Patients With Knee Osteoarthritis Receiving a Prosthesis
Patients with osteoarthritis of the knee undergo visible joint changes in radiology and Magnetic resonance imaging (MRI) tests, but also clinically and histologically.
- Conditions
- Osteoarthritis, Knee, Perfusion, Bone Marrow, Magnetic Resonance Imaging
- Trial name
- Chondrolike (NCT03644420)
- Testing
- Clinical evaluation, Radiology, Dynamic contrast-enhanced magnetic resonance imaging
- Volunteers
- 22 people
- Sponsor
- Lille Catholic University
Osteoarthritis, Knee Cutaneous Suture, Dermabond, Subcuticular Suture
Comparison of Postoperative Wound Between Dermabond Prineo(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) and Subcuticular Suture in Simultaneous Total Knee Arthroplasty
This study aims to compare the clinical results of postoperative wound between Dermabond PRINEO™(2-octyl Cyanoacrylate adhesive and polyester mesh) and subcuticular suture in simultaneous total knee arthroplasty There is previous…
- Trial name
- NCT04506580
- Testing
- DERMABOND™ PRINEO™(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) vs subcuticular nylon suture
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- The Catholic University of Korea
Osteo Arthritis Knee
A Study to Evaluate the Safety of Human Allogeneic Bone-Marrow-Derived Mesenchymal Stromal Cell Product StromaForte for the Treatment of Knee Osteoarthritis
This open-label, single-arm, phase I/II study in mild-to-moderate stage knee osteoarthritis patients is designed to assess the safety and tolerability of intraarticular human allogeneic bone marrow-derived mesenchymal stromal…
- Trial name
- NCT06084988
- Testing
- Human Allogenic Bone-Marrow-Derived Mesenchymal Stromal Cell Product (StromaForte)
- Where
- United Arab Emirates
- Volunteers
- 12 people
- Sponsor
- Cellcolabs Clinical SPV Limited
Rheumatoid Arthritis, Myositis
Comparison of Training Load With/Out Blood Flow Restriction Training in Rheumatoid Populations
The study will investigate the effects of a traditional, high-intensity strengthening program compared to an investigational low-intensity strengthening program that also uses blood flow restriction as part of the training…
- Conditions
- Rheumatoid Arthritis, Myositis, Osteoarthritis, Weakness, Muscle
- Trial name
- NCT04309227
- Testing
- Strength Training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Hand Osteoarthritis
Topical Clobetasol Propionate for Inflammatory Hand Osteoarthritis
This is a randomized, double-blind, comparative trial evaluating the efficacy on pain intensity between topical Clobetasol Propionate 0.05% and placebo in patients with symptomatic hand osteoarthritis.
- Trial name
- PROCLAME (NCT07812701)
- Testing
- Propionate de Clobétasol ( 0.05 %)
- Where
- France
- Volunteers
- 187 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis
Uncemented Tritanium TKR vs Cemented Triathlon TKR
The Study aims to investigate whether there is a clinically important difference in peri-articular bone mineral density (BMD) and trabecular bone score (TBS) between patients undergoing two different types of knee replacement…
- Trial name
- NCT04040764
- Testing
- Tritanium uncemented Total Knee Replacement
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Total Knee Arthroplasty, Manual Lymphatic Drainage
Manual Lymphatic Drainage Before and After Total Knee Replacement, a Single-center Observer-blinded Randomized Controlled Trial
The aim of this observer-blinded randomized controlled trial is the evaluation of the influence of manual lymphatic drainage (MLD) on the outcome of patients receiving total knee replacement (TKA).
- Conditions
- Total Knee Arthroplasty, Manual Lymphatic Drainage, MLD, Rehabilitation
- Trial name
- NCT05119764
- Testing
- Manual Lymphatic Drainage
- Where
- Austria
- Volunteers
- 112 people
- Sponsor
- Moritz Wagner
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