Clinical trials: Degenerative Osteoarthritis
Pain, Osteoarthritis, Hip
Modulation of the Surgical Inflammatory Response by Etoricoxib
The purpose of this study is to test the hypothesis that orally administered etoricoxib (COX-2) modulates prostaglandin and cytokine synthesis in the central nervous system (CNS) and in the periphery in surgical patients and thus…
- Conditions
- Pain, Osteoarthritis, Hip, Postoperative Pain
- Trial name
- NCT00746720
- Testing
- Etoricoxib 60 mg
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Osteoarthritis, Stem Cells
Treatment of Osteoarthritis With the Stromal Vascular Fraction of Abdominal Adipose Tissue - a Pilot Study
To investigate the feasibility and short term safety issues of treatment of knee osteoarthritis with intra-articular injection with the stromal vascular fraction of abdominal adipose tissue (SVF) harvested and prepared using the…
- Trial name
- NCT02697682
- Testing
- injection with the stromal vascular fraction (SVF) of adipose tissue
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Hvidovre University Hospital
Osteoarthritis Nos, of Sacroiliac Joint
Optimal Performance of RFA of the Nerves Supplying the Posterior Sacroiliac Joint Complex.
The procedure is supposed to ablate the sacral lateral branches that form the medial cluneal nerves (MCN). The anatomy of the sacral lateral branches is such that, in addition to innervating the SIJ, distal branches of these…
- Trial name
- NCT02808962
- Testing
- Cooled RFA of sacral lateral branches
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Milton S. Hershey Medical Center
Knee Acute and Chronic Pain
Acute Effect of Inferential Therapy (IFT) and Short Wave Diathermy (SWD) on Balance in Subjects With Knee Pain
Background: The Y balance test is a dynamic test that requires strength, flexibility, and proprioception. It is a measure of dynamic balance that provides a significant challenge to athletes and physically active individuals.
- Trial name
- IFT & SWD (NCT04148768)
- Testing
- Inferential therapy, short wave diathermy
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Khalid University
Coxarthrosis
Compaction Total Hip Arthroplasty (THA) Bilateral
This is a prospective, randomized study comparing two different bone preparation techniques for insertion of a porous coated titanium cementless femoral stem.
- Trial name
- NCT00317889
- Testing
- Bone preparation technique: compaction, Bone preparation technique: broaching
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Osteoarthritis, Knee, Osteoarthritis, Hip
Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee
The primary objective of the study is to evaluate the effect of fasinumab compared to placebo on peripheral nerves in participants with pain due to Osteoarthritis (OA) of the hip or knee.
- Trial name
- NCT03691974
- Testing
- Fasinumab
- Where
- 47 sites in United States, Poland and 1 more
- Volunteers
- 180 people
- Sponsor
- Regeneron Pharmaceuticals
Low Back Pain
Effectiveness of Facet Joint Infiltration in Low Back Pain
The purpose of this study is to evaluate the effectiveness of facet joint infiltration with corticosteroids in the treatment of low back pain due to facet joint osteoarthritis.
- Trial name
- NCT01447160
- Testing
- Cortisone
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Osteoarthritis, Knee
Calypso Knee System Clinical Sub-study, OUS Continued Evaluation
Calypso Knee System Clinical Study, OUS for subjects with symptomatic osteoarthritis of the medial compartment of the knee. The sub-study will achieve continued evaluation of the safety and clinical effectiveness of the Calypso…
- Trial name
- NCT04548882
- Testing
- Calypso Knee System
- Sponsor
- Moximed
Hallux Valgus, Hallux Rigidus
The Effect of Weight Bearing on Patient Outcomes Following 1st MTP Joint Fusion
randomized-controlled trial looking specifically at the effect of weight bearing on the outcomes of first MTP joint fusions
- Trial name
- NCT04473196
- Testing
- weightbearing
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Nova Scotia Health Authority
Osteoarthritis of the Knee, Type 2 Diabetes Mellitus
Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of the Knee and Type 2 Diabetes
The purpose of this study was to compare the effects of FX006 and Triamcinolone Acetonide Injectable Suspension, United States Pharmacopeia (USP) (referred to as TCA IR in the protocol) on blood glucose (BG) in patients with…
- Trial name
- NCT02762370
- Testing
- FX006 32 mg, TCA IR 40 mg
- Where
- 8 sites in United States
- Volunteers
- 33 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis
Pivotal Study to Evaluate Efficacy and Safety of SP5M002 Inj. as Compared to Synovian Inj. in Patients With Mild to Moderate Knee Osteoarthritis
This is a randomized, double-blind, multicenter, Active Controlled, pivotal clinical trial to assess the efficacy and safety of the novel hexamethylenediamine (HMDA) cross-linked hyaluronate intra-articular injection (SP5M002)…
- Trial name
- NCT06399042
- Testing
- SP5M002 inj, Synovian inj
- Where
- 16 sites in South Korea
- Volunteers
- 297 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Coxarthrosis; Primary
Efficacy of Pulse Radiofrequency Treatment in Patients With Coxarthrosis
Our aim in this interventional study is to investigate the effectiveness of pulsed radiofrequency (PRF) treatment applied to the articular branches of the femoral and obturator nerves on pain, functional level, functional…
- Trial name
- NCT06034418
- Testing
- Pulse radiofrequency treatment, Nerve block with 1 cc betamethasone and 1 cc 1% lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara City Hospital Bilkent
Hip Osteoarthritis
Prospective Clinical Follow-up of the Echo Bi-Metric Microplasty Stem for Total Hip Arthroplasty
The primary objective of this study is to characterize survivorship of the Echo Bi-Metric Microplasty stem in unilateral or bilateral primary total hip arthroplasty at 5 years postoperative.
- Trial name
- NCT04326010
- Testing
- Surgery
- Where
- 6 sites in United States
- Volunteers
- 206 people
- Sponsor
- Zimmer Biomet
Arthropathy, Hip Arthropathy
Restoration Anatomic Acetabular Shell Revision Study
This study will be a non-randomized, ambidirectional (retrospective and prospective) study where all subjects will be followed prospectively.
- Conditions
- Arthropathy, Hip Arthropathy, Hip Osteoarthritis
- Trial name
- RAS (NCT05591859)
- Testing
- Restoration Anatomic Acetabular Shell
- Where
- United States
- Sponsor
- Stryker Orthopaedics
Knee Osteoarthritis, Bone; Deformity, Congenital
COREV 2.0 PMCF-Study on Manual and Navigated Revision Knee Patients
The Columbus® Revision endoprosthetic system is bearing the CE-mark. This means that within the scope of this observational study the patient will not be subjected to any additional stressful, study-related medical examinations…
- Conditions
- Knee Osteoarthritis, Bone; Deformity, Congenital, Prosthesis Failure, Prosthesis-Related Infections
- Trial name
- COREV (NCT05113303)
- Testing
- Navigated Revision Total Knee Arthroplasty, Manual Revision Total Knee Arthroplasty
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Knee Osteoarthritis
Effectiveness of Inertial Sensors vs the Conventional Technique for the Execution of the Bone Resections in Primary TKA
Comparison of surgical technique for the execution of bone resections in total knee arthroplasty. Used technique are: a non-invasive extramedullary technique (EM technique) based on the use of inertial sensors for cutting guides…
- Trial name
- NCT04242303
- Testing
- Total knee replacement
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Injury, Knee Osteoarthritis
Monitoring Of Helsingborg Acute Knee Injuries (MOHAK)
Using magnetic resonance imaging (MRI), laboratory analyses and patient reported outcomes, the overall aim of this study is to investigate structural injuries and biochemical alterations in the acutely injured knee and to relate…
- Trial name
- NCT01382173
- Where
- Sweden
- Volunteers
- 192 people
- Sponsor
- Lund University
Osteoarthritis Arthritis, Rheumatoid Arthritis
G7 Acetabular System vs. Exceed ABT Acetabular System in THA
Evaluate the safety and effectiveness of patients who received G7 Acetabular system in conjunction with Ceramic on Ceramic articulation and Taperloc Complete Microplasty stem compared to patients who received the Exceed ABT…
- Trial name
- G7 (NCT02340390)
- Testing
- G7, Exceed ABT
- Where
- 3 sites in South Korea
- Volunteers
- 160 people
- Sponsor
- Zimmer Biomet
Osteoarthritis
Chinese Herbal Fumigation With Acupuncture for the Knee Osteoarthritis
To evaluate the effect of fumigation in conjunction with acupuncture for knee osteoarthritis, participators were collected from acupuncture and Chinese traumatology clinic at Linsen Chinese Medicine and Kunming Branch, Taipei…
- Trial name
- NCT03659370
- Testing
- Fumigation, Acupuncture
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Taipei City Hospital
Osteoarthritis, Knee
Treatment of Osteoarthritis With Autologous, Microfragmented Adipose Tissue.
The study is a blinded, multicenter, randomized, controlled trial with participants individually randomized to one of two parallel groups: 1.
- Trial name
- NCT03771989
- Testing
- autologous, micro-fragmented adipose tissue, Saline
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
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