Clinical trials: Deglutition Disorder
Multiple Sclerosis, Dysphagia
Myotonometer Analyses of Muscles in Multiple Sclerosis Patients With Dysphagia
Multiple Sclerosis is a chronic inflammatory autoimmune neurological disease characterized by the destruction of myelin in the central nervous system, grey matter and axonal loss.
- Conditions
- Multiple Sclerosis, Dysphagia, Swallowing Disorder, Deglutition Disorders
- Trial name
- NCT04369092
- Testing
- DYMUS
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Tuba Maden
Head and Neck Cancer, Adaptive Radiotherapy
Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors
Adaptive radiotherapy (ART) includes image-guided radiotherapy (IGRT) and also offers further possibilities for plan adaptation.
- Conditions
- Head and Neck Cancer, Adaptive Radiotherapy, Radiation, Optimized Treatment
- Trial name
- ART in HNT (NCT06214611)
- Testing
- Adaptive Radiotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen
Stroke, Dysphagia
Effect of Theta Burst Transcranial Magnetic Stimulation on Patients with Dysphagia After Stroke
The purpose of this study was to observe the effect of Theta burst transcranial magnetic stimulation (TBS) on swallowing function in patients with dysphagia after stroke (PSD).
- Conditions
- Stroke, Dysphagia, Functional Near- Infrared Spectroscopy, Transcranial Magnetic Stimulation
- Trial name
- NCT06471309
- Testing
- Theta burst transcranial magnetic stimulation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Zhang Xiaohui
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine
Effect of Intravenous Corticosteroid Injections on Dysphagia After Cervical Spine Surgery
This is a randomized, double-blind, placebo-controlled study to examine the effect of local intravenous steroids following anterior cervical spine surgery on the development of dysphagia in patients.
- Trial name
- NCT02266797
- Testing
- Dexamethasone, Saline
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Paraesophageal Hernia, Gastro Esophageal Reflux
Partial Versus Total Fundoplication in the Surgical Repair of Para-esophageal Hernia.
Short-term follow up after surgery of para-esophageal hernia comparing two different types of fundoplication
- Trial name
- NCT04436159
- Testing
- Addition of 360 fundoplication after crural closure, Addition of 180 posterior fundoplication after crural closure
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Karolinska University Hospital
Gastroesophageal Reflux
Effect of Tube Feeding on Gastroesophageal Reflux in Preterm Infants
Due to several promoting factors, gastro-esophageal reflux (GER) is very frequent in preterm infants. To limit the potentially harmful widespread of pharmacological treatment, a step-wise approach, which firstly undertakes…
- Trial name
- FT-GER-SO (NCT02837627)
- Testing
- Tube feeding
- Where
- 2 sites in Italy
- Volunteers
- 31 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Gastroesophageal Reflux Disease
Feasibility Study for Evaluating the Effect of Electrical Stimulation on Lower Esophageal Sphincter Pressure and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease
The EndoStim Stimulation System is an investigational device intended to improve the lower esophageal sphincter (LES) resting tone and restore LES function in individuals suffering with gastroesophageal reflux disease (GERD).
- Trial name
- NCT01578642
- Testing
- EndoStim LES Stimulation System
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- EndoStim Inc.
Dysphagia
Nutrition-dense Smoothie Diets Reduced Dysphagia Risk in the Elderly
The investigators aimed to compare the effect of consuming high protein (23-34% energy ratio) and low carbohydrate (25-38% energy ratio) smoothie formulas vs.
- Trial name
- NCT04901182
- Testing
- the effect of consuming diets on the swallowing capacity by using Flexible Endoscopic Evaluation of Swallowing (FEES)
- Where
- Thailand
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dysphagia
Clinical and Instrumental Assessment Tools for Neurogenic Dysphagia: Translation and Validation
This study aims to translate and validate Italian versions of several clinical assessment tools for patients with neurogenic dysphagia.
- Trial name
- Val_Dysphagia (NCT07549724)
- Testing
- dysphagia assessment
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Gastroesophageal Reflux
Hyaluronic Acid in Patients With Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) remains one of the most common pathologies seen among gastroenterologists, surgeons, and primary care physicians.
- Trial name
- NCT05561179
- Testing
- Hyaluronic acid injection, Sodium chloride injection (control group)
- Where
- Ecuador
- Volunteers
- 120 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Achalasia Cardia, Achalasia
Full-thickness Versus Progressive Myotomy in Peroral Endoscopic Esophageal Myotomy in Achalasia: A Randomized Controlled Trial
Peroral endoscopic esophageal myotomy (POEM) has been established as an effective therapy for Achalasia. It is still not known how deep the myotomy should be and if it should include the circular and longitudinal muscles or not.
- Trial name
- NCT07875686
- Testing
- Full thickness myotomy, Progressive thickness myotomy
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Mitral Valve (MV) Regurgitation
DragonFly M2 Pivotal Study
To confirm the effectiveness and safety of the DragonFly M2 Transcatheter Mitral Valve Repair System for the treatment of symptomatic moderate-to-severe (3+) or severe (4+) degenerative mitral regurgitation in high surgical risk…
- Trial name
- NCT07243197
- Testing
- DragonFly M2 Transcatheter Mitral Valve Repair System
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Hangzhou Valgen Medtech Co., Ltd
Dysphagia
Effect of Oral Neuromuscular Training on Swallowing
In this randomized controlled trial the investigators wish to investigate the effect of an oral neuromuscular training device (called IQoro) on swallowing function and time until decannulation from a tracheostomy tube, in…
- Trial name
- NCT05235282
- Testing
- IQoro, Usual care for swallowing function
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- University of Aarhus
Parkinson's Disease
DBS Frequency on Swallowing Function in Parkinson's Disease
The stimulation frequency has been found to affect the axial symptoms of freezing of gait (FOG) and speech in advanced Parkinson's disease (PD) patients with subthalamic nucleus deep brain stimulation (STN DBS), with the…
- Trial name
- NCT01935011
- Testing
- PD, DBS
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Chicago
Gastroesophageal Reflux
A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn
The purpose of this study is to determine whether Dexlansoprazole once daily (QD) is effective in treating patients with night heartburn.
- Trial name
- NCT00627016
- Testing
- Dexlansoprazole
- Where
- 43 sites in United States
- Volunteers
- 305 people
- Sponsor
- Takeda
Gastroesophageal Reflux Disease, GERD
What is the Predictive Value of the Reflux Impact Scale
Gastric distress is a common phenomenon in our society. Heartburn and regurgitation occur daily in about 7% of the adult population,weekly 14-20% pf the adults and monthly in 34-44% of adults.
- Conditions
- Gastroesophageal Reflux Disease, GERD, Heartburn, Acid Regurgitation
- Trial name
- PREDICT (NCT00536328)
- Volunteers
- 938 people
- Sponsor
- AstraZeneca
Head and Neck Cancer, Dysphagia
QUantitative Assessment of Swallowing After Radiation (QUASAR)
To use novel methods for quantitative analysis of VFSS (videofluoroscopic swallow study, also known as modified barium swallow) to study and compare dysphagia in patients treated for head and neck carcinoma with concurrent…
- Conditions
- Head and Neck Cancer, Dysphagia, Oropharyngeal Dysphagia, Oropharynx Cancer
- Trial name
- QUASAR (NCT04359199)
- Testing
- Radiation Therapy, Cetuximab, Chemotherapy
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Loren Mell, MD
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea
Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF
This study will evaluate the effect of CPAP therapy on esophageal pH and lung inflammation in patients with idiopathic pulmonary fibrosis (IPF) and sleep apnea.
- Conditions
- Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Gastro Esophageal Reflux
- Trial name
- NCT05359965
- Testing
- Positive Airway Pressure
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Arizona
Rheumatoid Arthritis (RA
Dysphagia in Rheumatoid Arthritis
The primary goal of this cross-sectional study is to assess risk factors/predictors for dysphagia in RA. The secondary goals include demonstrating whether flexible fiberoptic pharyngolaryngoscopy can detect…
- Trial name
- NCT07401732
- Testing
- flexible fiberoptic pharyngolaryngoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Cough, Cough Variant Asthma
MCT and Capsaicin Provocation Challenge in Diagnosis of Chronic Cough
The aim of the study is to assess the prevalence of bronchial hyperresponsiveness (BHR) in non-smoking adults with chronic cough and the prevalence of BHR in patients with upper airway cough syndrome (UACS) and gastroesophageal…
- Conditions
- Cough, Cough Variant Asthma, Upper-Airway Cough Syndrome, GERD
- Trial name
- NCT03363698
- Testing
- Cough variant asthma treatment
- Where
- Poland
- Volunteers
- 55 people
- Sponsor
- Medical University of Warsaw
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.