Clinical trials: Deglutition Disorder
Stroke, Dysphagia
Effects of CTAR and a Swallowing Pressure Ball in Older Stroke Adults
This study aims to investigate the effectiveness of resistance swallowing rehabilitation using Chin Tuck Against Resistance (CTAR) exercises combined with an innovative swallowing pressure ball in improving swallowing function…
- Conditions
- Stroke, Dysphagia, Post-Stroke Dysphagia
- Trial name
- NCT07620210
- Testing
- Innovative Swallowing Pressure Measurement Ball Combined With CTAR Training, Conventional Swallowing Rehabilitation
- Where
- Taiwan
- Volunteers
- 132 people
- Sponsor
- Chimei Medical Center
Dysphagia After Stroke, Aspiration Pneumonias
Tongue Brush (Orabrush) for Reducing Aspiration Pneumonia in Stroke Patients
The investigators conduct a controlled prospective experimental intervention study to examine whether the use of a tongue brush (Orabrush) can improve the rate of aspiration pneumonia and dysphagia in patients with ischemic…
- Conditions
- Dysphagia After Stroke, Aspiration Pneumonias, Ischemic Stroke
- Trial name
- StrOra (NCT06765018)
- Testing
- Tongue Brush (Orabrush)
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- University Hospital Marburg
Stroke, Dysphagia
Pilot Study of Efficacy of Mechanical Insufflation Exsufflation in Stroke
Stroke patients with dysphagia have restrictive lung dysfunction and impaired cough response. This pilot study was performed to determine if Mechanical Insufflation Exsufflation (MIE) therapy can help recover impaired cough…
- Trial name
- NCT02080806
- Testing
- Mechanical Insufflation Exsufflation
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- The Catholic University of Korea
Swallowing Difficulties, Thirst
Effect of Cold Water Spray on Swallowing Difficulty, Pain, and Thirst After Thyroid Surgery
Dysphagia and thirst are common in the early period after thyroidectomy and negatively affect patient comfort. This study aims to evaluate the effect of cold water spray on dysphagia, pain during swallowing, and thirst after…
- Conditions
- Swallowing Difficulties, Thirst, Thyroidectomy
- Trial name
- CWS-THY (NCT07879404)
- Testing
- Cold water spray
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Oral Cancer, Reconstructive Surgery
App-Assisted Swallowing Program After Oral Cancer Surgery
This study aims to examine the effects of a swallowing care program combined with an exercise mobile application (App) on swallowing function, anxiety, and quality of life in patients with oral cancer after flap reconstruction…
- Conditions
- Oral Cancer, Reconstructive Surgery, Postoperative
- Trial name
- AASP (NCT07301047)
- Testing
- Swallowing Care + Exercise App, Routine Postoperative Care
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- Chang Gung Memorial Hospital
Sarcopenia, Dysphagia
Feasibility and Impact of Resistance Training for Sarcopenic Dysphagia
The purpose of the study is to test and optimize the feasibility of an activity-based resistance training program for patients with sarcopenic dysphagia.
- Trial name
- NCT05269758
- Testing
- activity-based resistance training of ingestive skills (ACT-ING-program)
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Hvidovre University Hospital
Gastro-esophageal Reflux Disease (GERD)
Compound Sodium Alginate Oral Suspension Sachet 4-hour Esophageal pH Study in GERD Patients
Multi-centre, randomised, open-label, placebo-controlled, two-period crossover study of 4 hour pH monitoring following a refluxogenic meal and drink.
- Trial name
- NCT02619747
- Testing
- Compound Sodium Alginate Oral Suspension sachet
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
GERD
A Study to Evaluate the PK, PD and Safety of CKD-382 in Healthy Subjects
to evaluate the pharmacokinetics, pharmacodynamics and safety after single/multiple administration of CKD-382, D860 and D027 in healthy subjects
- Trial name
- NCT05108038
- Testing
- CKD-382, D860, D027
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Dysphagia, Dysphonia
Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)
This study examines the presence, severity and natural history of dysphagia and dysphonia in the post-extubation and severely unwell COVID-19 patient.
- Conditions
- Dysphagia, Dysphonia, Subglottic Stenosis, Voice Disorders
- Trial name
- DYADS (NCT04584658)
- Testing
- Fibreoptic Endoscopic Evaluation of Swallowing (FEES), Videofluoroscopy, Dysphagia Handicap Index (DHI)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Laryngopharyngeal Reflux, Obstructive Sleep Apnea
Effect of CPAP Therapy on LPR Among Patients With OSAS
This study will investigate the changes in the reflux symptom index (RSI) and reflux finding score (RFS) among patients with obstructive sleep apnea after regular humidified CPAP therapy.
- Trial name
- NCT03455803
- Testing
- CPAP
- Volunteers
- 30 people
- Sponsor
- Assiut University
Ineffective Esophageal Motility, GERD (Gastroesophageal Reflux Disease)
The Influence of Specialized Food Products Based on Ice-Cream on Esophageal Motility
This study aims to assess the influence of specialized products based on ice cream on esophageal motility
- Trial name
- MICE (NCT07121803)
- Testing
- specialized food based on ice cream, order 1, specialized food based on ice cream, order 2, specialized food based on ice cream, order 3
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution
Head and Neck Cancer
Adherence to Swallowing Exercises in Head and Neck Cancer
The goal of this research study is to help patients complete the swallowing and dental care exercises they are supposed to perform during radiation treatment.
- Trial name
- NCT00761397
- Testing
- Interview, Phone Call, Brochure
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- M.D. Anderson Cancer Center
Gastro Esophageal Reflux
Effect of Right Lateral Position on Ventilated Preterm Neonates
Objective: to evaluate the effect of right lateral positioning in comparison with supine positioning on tracheal aspirate pepsin levels as a marker of aspiration of gastric contents in ventilated preterm neonates.
- Trial name
- NCT03258528
- Testing
- positioning
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Dysphagia of Newborn
The Effects of Pacifier-Activated Lullaby on Oral Feeding Among Preterm Infants
Preterm infants often have difficulty learning how to feed by mouth because the coordination of sucking, swallowing, and breathing develops later in pregnancy.
- Trial name
- Music therapy (NCT07819734)
- Testing
- Pacifier-Activated Lullaby (PAL) Therapy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Dysphagia
Phagenyx® Registry Study
A retrospective, open-label, matched-control registry study designed to characterize the effectiveness of Pharyngeal Electrical Stimulation (PES) to improve swallowing in patients with severe dysphagia post stroke when delivered…
- Trial name
- RESTORE-US (NCT06866418)
- Testing
- 1. Phagenyx® System Group Patients
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Phagenesis Ltd.
Stroke
Neuromuscular Electrical Stimulation Versus Electromyographic Biofeedback on Oropharyngeal Dysphagia in Patients With Stroke
This study aims to investigate the effect of neuromuscular electrical stimulation versus electromyographic biofeedback on swallowing function and dysphagia severity in patients with stroke.
- Trial name
- NCT07367490
- Testing
- Neuromuscular electrical stimulation, Electromyographic Biofeedback, Selected physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Air Insufflation, Regurgitation
Risk of Gastric Insufflation Related to Facemask Ventilation Technique During Anaesthetic Induction, With or Without PEEP
Continuous positive pressure during anesthetic induction is today not routinely used partly a to the risk of gastric insufflation because of higher ventilatory pressures.
- Trial name
- NCT02238691
- Testing
- Mask ventilation with PEEP via a face mask device
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Cholecystolithiasis, Cholecystectomy
Does Cholecystectomy Increase the Esophageal Alkaline Reflux? Evaluation by Impedance-pH Technique
Publications with different conclusions are available with regard to the correlations between the cholecystolithiasis, cholecystectomy and gastroesophageal reflux disease (GERD).
- Conditions
- Cholecystolithiasis, Cholecystectomy, Gastroesophageal Reflux
- Trial name
- NCT01047085
- Testing
- impedance pH measurement
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Nutrition Disorders, Gastrointestinal Disease
Review of Infant Oral Feeding and Skills
This study evaluates the infant's feeding skill level at discharge from the neonatal intensive care unit. The goal is to determine whether the ability to "full feed by volume" implies "full skill development" for infant oral…
- Conditions
- Nutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding Difficulties
- Trial name
- RIOS (NCT06736743)
- Testing
- SMART Tool for Feeding Skill Assessment
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Wake Forest University Health Sciences
Barrett Esophagus, Gastroesophageal Reflux
Assessment of Zegerid on Esophageal pH in Patients With Barrett's Esophagus
The purpose of this research study is to assess how safe, effective (how well it works), and tolerable (to put up with) the drug Zegerid is in reducing reflux episodes in patients who have both gastroesophageal reflux disease…
- Trial name
- NCT01129778
- Testing
- Zegerid (proton pump inhibitor), Bravo pH monitoring
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Stanford University
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