Clinical trials: Deglutition Disorder
Dysphagia, Oropharyngeal
Oral Screens in Post Stroke Training
Stroke is a common disease in older people, and often leads to various degrees of disability. Dysphagia is one such consequence which is associated with aspiration pneumonia and malnutrition.
- Trial name
- NCT03167892
- Testing
- Oral screen
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Dysphagia, Laryngeal Edema
Corticosteroids for Post-Extubation Dysphagia
This is a placebo-controlled, double-blind randomized trial of a short course of intravenous corticosteroids for Acute Respiratory Failure Survivors with Fiberoptic Endoscopic Evaluation of Swallowing (FEES) documented laryngeal…
- Trial name
- COPED (NCT06670521)
- Testing
- Methylprednisolone, Normal Saline
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Swallow, Preterm Infant
Effect of Kinesio-taping Technique on Oral Feeding in Late Preterm Infants
Difficulty in feeding among late preterm infants is one of the most significant factors contributing to prolonged hospitalization and re-admissions.
- Conditions
- Swallow, Preterm Infant, Newborn, Kinesiotaping
- Trial name
- NCT06208228
- Testing
- Kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ondokuz Mayıs University
Dysphagia, Heart Transplant Recipients
Respiratory Strength Training in Heart Transplant Recipients
This research study is investigating whether completing breathing exercises before surgery helps heart transplant patients recover after surgery.
- Trial name
- NCT06190171
- Testing
- Active respiratory muscle strength training
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center
Head and Neck Cancer
Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area
The purpose of this clinical investigation is to evaluate acute and longlasting side effects in patients undergoing radiotherapy for cancer treatment in the head and neck area.
- Trial name
- NCT00995319
- Where
- Norway
- Volunteers
- 58 people
- Sponsor
- Norwegian University of Science and Technology
Deglutition Disorders, Stroke
Computerized Acoustic Swallowing Evaluation
It is the purpose of this study to determine if a commercially available electronic stethoscope synchronized with an smart phone or iPad application can be used as an accurate and objective screening tool for measuring dysphagia.
- Trial name
- CASE (NCT02925507)
- Testing
- Swallowing Screen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Systemic Sclerosis With Dysphagia
Clinical Usefulness and Influence on Esophageal Motility of Pyridostigmine for Dysphagia in Systemic Sclerosis
Systemic sclerosis is characterized by progressive fibrosis of different organ systems. With a longer duration, the risk of gastrointestinal involvement increases.
- Trial name
- NCT06915181
- Testing
- Pyridostigmine
- Sponsor
- Universitair Ziekenhuis Brussel
Dysphagia
Large-Scale Study of Oro-esophageal Feeding Versus Nasogastric Feeding for Swallowing Function and Airway Protection
This is a randomized controlled trial involving patients with ischemic stroke and dysphagia. The aim of this study is to explore the recovery speed and therapeutic effect of oro-esophageal feeding compared with nasogastric…
- Trial name
- IOEfinal (NCT07386834)
- Testing
- Oro-esophageal Feeding, Nasogastric Feeding, Rehabilitation care
- Volunteers
- 422 people
- Sponsor
- Zeng Changhao
Mitral Valve Stenosis With Incompetence or Regurgitation
The Effects of Levosimendan During Mitral Valve Surgery
The effects of levosimendan on renal function in patients with low ejection fraction undergoing mitral valve surgery will be investigated in a prospective, double-blinded, randomized clinical trial using serum creatinine…
- Trial name
- NCT01969071
- Testing
- Levosimendan, Dobutamine
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Dysphagia, Oropharyngeal, Parkinson Disease
Benefit From the Chin Down Maneuver in the Swallowing Performance and Self-perception of Parkinson's Disease Patients
Objective: To verify the effectiveness of chin-down posture maneuver in swallowing therapy for Parkinson's disease (PD).
- Conditions
- Dysphagia, Oropharyngeal, Parkinson Disease, Speech Therapy, Orientation
- Trial name
- NCT02973698
- Testing
- chin-down posture maneuver, Orientations about swallowing, Control
- Volunteers
- 26 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Nasopharyngeal Carcinoma (NPC)
The Effectiveness of Structured Swallowing Exercise Therapy in Patients With Nasopharyngeal Carcinoma: An Assessment of Swallowing Function and Quality of Life
This study aims to evaluate the effectiveness of a structured swallowing exercise program compared with conventional swallowing exercises in patients with nasopharyngeal carcinoma.
- Trial name
- NCT07909538
- Testing
- Structured Swallowing Exercise, Conventional Swallowing Exercise
- Where
- Indonesia
- Volunteers
- 88 people
- Sponsor
- Ira Mistivani, dr. Sp.KFR.N.M.(K).
Gastroesophageal Reflux, Laryngitis
Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients
The purpose of this study is to evaluate the efficacy of rabeprazole (pariet) versus placebo in treating reflux laryngitis in Chinese patients.
- Trial name
- NCT00517114
- Testing
- Rabeprazole 20mg twice daily
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hospital Authority, Hong Kong
GERD (Gastroesophageal Reflux Disease)
Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult Volunteers
A Randomized, Open-label, Oral in healthy volunteers
- Trial name
- NCT07364838
- Testing
- DW4421
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Gastro Esophageal Reflux
Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study)
This will be a randomized clinical trial examining the efficacy and safety of ARAT (intervention group) in patients with chronic GERD symptoms (typical symptoms of GERD, i.e.
- Trial name
- AREA21 (NCT05570448)
- Testing
- ARAT
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Midwest Veterans' Biomedical Research Foundation
Esophageal Cancer, Reflux, Gastroesophageal
Evaluating Acid Reflux After Oesophageal Stenting Using Anti-reflux Stents
Incurable oesophageal cancer remains a global problem and in South Africa the vast majority of patients with oesophageal cancer have advanced disease at first presentation and are not curable.
- Trial name
- NCT05303298
- Testing
- Anti-reflux oesophageal stent, Conventional oesophageal stent
- Where
- South Africa
- Volunteers
- 72 people
- Sponsor
- University of Cape Town
Gastroesophageal Reflux Disease
Endoscopic Findings in Patients With Typical Gastroesophageal Reflux Disease (GERD) Symptoms
Gastroesophageal reflux disease (GERD) is diagnosed on the basis of characteristic reflux symptoms (i.e. troublesome heartburn and/or acid regurgitation).
- Trial name
- NCT00730106
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Lotung Poh-Ai Hospital
Deglutition Disorders in Infants, Bottle Feeding
Evaluation of the Effect of Flow Rate on Swallowing Function in Young Infants
The purpose of this study is to evaluate the effect of nipple flow rate on swallowing function in infants less than 3 months corrected age (up to 11 weeks and 6 days) who have been referred for videofluoroscopic swallow study.
- Trial name
- NCT03892811
- Testing
- Three study conditions
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Functional Gastrointestinal Disorders, Infant Conditions
Prevalence of FGIDs and Probiotics Study
This is a study to evaluate the prevalence of FGIDs in infants using the Thai version of Rome IV diagnostic questionnaire for functional gastrointestinal disorders in infants and evaluate the efficacy of Limosilactobacillus…
- Trial name
- PROOF (NCT06309199)
- Testing
- Biogaia
- Where
- Thailand
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Gastroesophageal Reflux
Correlations Between Wireless pH Monitoring and Variation in Reflux Symptom Questionnaire, 7 Day Recall
The diagnosis of gastro-oesophageal reflux disease (GORD) is often based on 24-hour catheter-based pH studies. The Bravo™ wireless pH monitoring revolutionised the study of GORD, allowing patients an improved comfort and ability…
- Trial name
- NCT03407456
- Testing
- Gastroesophageal reflux symptoms questionnaire
- Where
- United Kingdom
- Volunteers
- 199 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Dysphagia, Aspiration
Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia
Oropharyngeal dysphagia (OD) is a major complaint among many patients with stroke and causes severe complications. There is no specific treatment for these patients.
- Conditions
- Dysphagia, Aspiration, Stroke
- Trial name
- NCT01777672
- Testing
- Dietary and oral hygiene recommendations, oral TRPV1 agonist, pharyngeal electrical stimulation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital de Mataró
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.