Clinical trials: Dehiscence
Breast Cancer, Wound Dehiscence, Surgical
ciNPT in Autologous DIEP Flap Breast Reconstruction
In women who undergo mastectomy for the treatment of breast cancer, autologous reconstruction using the deep inferior epigastric perforator (DIEP) flap is a common surgical procedure that aims to restore both the appearance and…
- Trial name
- NCT05907941
- Testing
- ciNPT, Conventional Tape Dressings, DIEP Breast Reconstruction
- Volunteers
- 114 people
- Sponsor
- McMaster University
Immediate Implant
Immediate Implant Placement Using Immediate Dentoalveolar Restoration Versus Ice Cream Cone Technique With Labial Plate Dehiscence
: Evaluation of Soft and Hard Tissue Changes following Immediate Implant using Immediate Dentoalveolar Restoration Versus Ice Cream Cone technique for management of Cases With Labial Plate Dehiscence
- Trial name
- NCT05946954
- Testing
- Immediate Dentoalveolar Restoration, Ice cream cone technique
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aya Sharaf
Disruption or Dehiscence of Closure of Skull or Craniotomy
Incidence of Pain After Craniotomy in Children
The primary objective is to assess the incidence and severity of pain after major craniotomy in paediatric patients (from 1 month to 10 years of age).
- Trial name
- Brainpain (NCT01142830)
- Where
- 8 sites in Italy
- Volunteers
- 218 people
- Sponsor
- San Gerardo Hospital
Postoperative Complications, Surgical Wound Infection
Acupuncture and Post-Surgical Wound Healing
The purpose of this study is to determine if acupuncture improves wound healing. Since we, the investigators at the University of California, San Francisco (UCSF), know that how much oxygen is delivered to tissue is the best…
- Conditions
- Postoperative Complications, Surgical Wound Infection, Surgical Wound Dehiscence
- Trial name
- NCT00260494
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Francisco
Sternum Wound Infection, Nonunion of Fracture of Sternum
Sternal Closure With STERNUMFIX in Patients With High Risk
The primary objective is to establish if the SternumFix System improves sternal closure. The study should test the hypothesis that in a high risk patient population with increased risk for the development of sternal wound…
- Trial name
- STEPHIX (NCT01408745)
- Testing
- Sternumfix, steel wire
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 166 people
- Sponsor
- Aesculap AG
Fracture of Tibia, Wound Heal
Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures
This is a multi-center, pragmatic, parallel arm randomized controlled trial (RCT) of 352 patients with high-risk open or closed tibial plateau fracture, high-risk open or closed tibial pilon fracture, or open tibial shaft…
- Conditions
- Fracture of Tibia, Wound Heal, Infected Wound, Wound Complication
- Trial name
- iVAC (NCT06337292)
- Testing
- Incisional Negative Pressure Wound Therapy (NPWT)
- Where
- 6 sites in United States
- Volunteers
- 352 people
- Sponsor
- Major Extremity Trauma Research Consortium
Cesarean Section; Complications, Wound, Dehiscence
Effect of Bioptron Light Therapy on Wound Healing After Caesarean Section
The purpose of this study is to investigate the effect of Bioptron light therapy on wound healing after caesarean section.
- Trial name
- NCT07693478
- Testing
- Standard Postoperative Medical Care, Bioptron Light Therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Surgical Incision, Ulcer Foot
Study to Evaluate the PICO 14 Negative Pressure Wound Therapy System in the Management of Acute and Chronic Wounds
This is a prospective, multi-center, open label study evaluating the performance of PICO14 Negative Pressure Wound Therapy (NPWT) in the management of chronic open wounds (pressure ulcers, venous leg ulcers, diabetes related foot…
- Conditions
- Surgical Incision, Ulcer Foot, Ulcer Venous, Ulcer, Leg
- Trial name
- PICO14 (NCT05234632)
- Testing
- PICO 14 single-use Negative Pressure Wound Therapy System
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 45 people
- Sponsor
- Smith & Nephew, Inc.
Orthodontics, Orthognathic Surgical Procedures
Effects of Orthognathic Surgery on Root Resorption and Soft Tissues
The aim of this study is to evaluate the three-dimensional tomographic and photographic evaluation of the provision of two different orthognathic surgeries on hard and soft tissues with informative Class III deformity due to…
- Trial name
- NCT06873451
- Testing
- Surgery First, Surgery Early
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gokhan Coban
Cesarean Scar Niche, Cesarean Wound; Dehiscence
Cesarean Scar Characteristics After Scheduled and Emergency Cesarean Deliveries
This study was designed to evaluate the scar characteristics following scheduled and emergency cesarean deliveries.
- Conditions
- Cesarean Scar Niche, Cesarean Wound; Dehiscence, Cesarean Section; Dehiscence
- Trial name
- NCT03609281
- Testing
- Ultrasound assessement of uterine scar
- Where
- Egypt
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Tanta University
Hypospadias
Caudal vs Local Anesthesia in Hypospadias
Hypospadias is one of the most common congenital malformations of the genitalia in boys, and is typically managed by surgical intervention.
- Trial name
- CLASH (NCT02512887)
- Testing
- Caudal Block Anesthesia, Dorsal Penile Block Anesthesia
- Where
- 4 sites in Canada
- Volunteers
- 224 people
- Sponsor
- McMaster University
Sternal Dehiscence, Sternal Infection
Improvement of Hemostasis Techniques After Median Sternotomy
The purpose of this study is to compare 2 different hemostatic agents (Bonewax and Ostene)to a control group with regards to bleeding, bone healing, pain and infection in a patient group all undergoing median sternotomy.
- Conditions
- Sternal Dehiscence, Sternal Infection, Sternal Pain
- Trial name
- NCT01134471
- Testing
- Ostene, Bonewax
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Scar, Cesarean Section; Dehiscence
A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section
To compare scar infiltration with 0.5-1% Lidocaine at a dose of 3 mg/kg (max dose 300 mg) or scar deactivation with acupuncture surface release technique to determine which is more effective in reducing pain in adult patients…
- Trial name
- NCT03936309
- Testing
- Scar Deactivation Surface Release Technique protocol, Scar Infiltration with 0.25-1% Lidocaine, Physical therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Jennifer Loomis
Post-operative Complications, Surgical Site Infection
The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions
The purpose of this study is to compare the post-surgical standard-of-care dressing to the Prevena™ Incision Management System in women undergoing Cesarean section surgery.
- Conditions
- Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
- Trial name
- NCT01450631
- Testing
- Prevena™ Incision Management System (PIMS), Standard-of-care Dressing
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- KCI USA, Inc
Wound Heal, Wound Dehiscence
Wound Closure After Total Knee Arthroplasty: Comparison of Polypropylene and Polyglactin 910 Suture.
Comparison of wound complication and scar formation in patient undergone bilateral total knee replacement comparison between polypropylene and polyglactin 910 suture.
- Conditions
- Wound Heal, Wound Dehiscence, Wound Complication
- Trial name
- NCT06373900
- Testing
- wound closure
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indus Hospital and Health Network
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Cesarean Section; Dehiscence, Abnormal Uterine Bleeding
Prevalence of Cesarean Section Niche in Women With Unexplained Abnormal Uterine Bleeding
Prevalence of Cesarean Section Niche in women With Unexplained Abnormal Uterine Bleeding
- Trial name
- Niche (NCT03130387)
- Testing
- Office Hysteroscope
- Volunteers
- 95 people
- Sponsor
- Ain Shams University
Dehiscence, Surgical Wound
Evaluation of Safety and Efficacy of Using Seraffix LTB - (Laser Tissue Bonding) System
The purpose of this study is to evaluate the safety and effectiveness of using Seraffix LTB system for soft tissue bonding.
- Trial name
- NCT00521755
- Testing
- Seraffix LTB
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Seraffix
Surgical Wound Dehiscence
Abdominal Wall Dehiscence After Laparotomy Closure in Abdominal Surgery: a Retrospective Observational Study on the Influence of the Suture Used
In this retrospective longitudinal observational study we compare the incidence of fascial dehiscence and incisional hernia in patients operated via abdominal wall incision, comparing the barbed suture Stratafix Symmetric to…
- Trial name
- SUTURA (NCT06501508)
- Testing
- Stratafix Symmetric
- Where
- 4 sites in Spain
- Volunteers
- 1,900 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Colo-rectal Anastomosis Dehiscence
The Role of Ghost Ileostomy in Laparoscopic Rectal Resection
To evaluate if the Ghost Ileostomy is really advantageous in laparoscopy we conducted a prospective randomized controlled study comparing 2 groups of patients undergoing anterior resection of the rectum laparoscopically.
- Trial name
- GILRR (NCT01861379)
- Testing
- Ghost Ileostomy
- Volunteers
- 107 people
- Sponsor
- University of Roma La Sapienza