Clinical trials: Dehydration
Pressure Ulcer
Case Series of Weekly Applications of dHACM in Treatment of Pressure Ulcers
A prospective case series investigating the efficacy and safety of dehydrated human amnion/chorion membrane (dHACM) in the treatment of patients with Stage II or III pressure ulcers
- Trial name
- NCT02861560
- Testing
- dHACM
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- MiMedx Group, Inc.
Dehydration
Study of Subcutaneous Rehydration With Recombinant Human Hyaluronidase for Infants and Children
The aim of the study is to evaluate the safety, effectiveness and ease of use of subcutaneous (SC) rehydration using HYLENEX-augmented SC infusion of fluids and electrolytes for the rehydration of pediatric patients with mild to…
- Trial name
- INFUSE-PR (NCT00477152)
- Testing
- hyaluronidase (human recombinant)/rehydration fluid
- Volunteers
- 52 people
- Sponsor
- Baxter Healthcare Corporation
Scarring, Spinal Stenosis
dHACM in Lumbar Decompression and Microdiscectomy Surgery
Prospective evaluation of the safety and efficacy of dHACM on clinical outcomes in lumbar laminectomy and microdiscectomy patients as assessed by Oswestry Disability Index.
- Conditions
- Scarring, Spinal Stenosis, Herniated Disc
- Trial name
- NCT02300909
- Testing
- Lumbar Decompression Surgery, Microdiscectomy Surgery, Dehydrated Human Amnion/Chorion Membrane (dHACM)
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- MiMedx Group, Inc.
Dehydration
Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase
The purpose is to evaluate the ease of use and technical challenges encountered during subcutaneous infusion of Lactated Ringer's (LR) solution, preceded by recombinant human hyaluronidase (hylenex), utilizing commonly used…
- Trial name
- INFUSE-AT (NCT00807885)
- Testing
- hylenex-facilitated subcutaneous Lactated Ringer's infusion
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Pressure Ulcer
A Single Center, Prospective, Case Series of the Treatment of Pressure Ulcers and Decubitus Ulcers.
The purpose of this study is to investigate the efficacy and safety of dehydrated amnion/chorion membrane (dHACM) in the treatment of patients with stage II or III pressure ulcer and decubitus ulcers
- Trial name
- NCT03529578
- Testing
- dHACM
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MiMedx Group, Inc.
Scarring
Dehydrated Human Amnion/Chorion Membrane (dHACM) for Recovery After Fractionated Ablative CO2 Laser Resurfacing of the Face
The purpose of this study is to evaluate the efficacy of dHACM (Dehydrated Human Amnion Chorion Membrane) for reducing time to healing when used in post-laser recovery following ActiveFX™ and DeepFx™ fractionated ablative CO2…
- Trial name
- NCT01995604
- Testing
- Application of Sterile 0.9% Saline Solution, Application of dHACM
- Where
- United States
- Sponsor
- MiMedx Group, Inc.
Dehydration
Oral Rehydration Solution and Dehydration Recovery
This is a prospective, randomized, controlled, blinded, crossover, study to evaluate the effects of an oral hydration solution.
- Trial name
- NCT06368765
- Testing
- Oral Rehydration Solution (ORS), Water
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Dialysis Related Complication, Dehydration
Continuous Registration of Bioimpedance During Hemodialysis
This studies aims at testing continuous registration of bioimpedance during hemodialysis and comparing the measurement with extracted liquid.
- Trial name
- DELAGE (NCT03990818)
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Mode Sensors AS
Venous Leg Ulcer
Evaluating the Efficacy of NeoThelium FT in the Treatment of Venous Leg Ulcers
This is a randomized controlled trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in treating venous leg ulcers.
- Trial name
- NCT06930768
- Testing
- Standard of Care, NeoThelium FT
- Volunteers
- 132 people
- Sponsor
- NuScience Medical Biologics, LLC
Hypertension, Hypertension,Essential
Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)
To obtain an assessment of the efficacy and safety of renal denervation by dehydrated alcohol injection, USP administered via the Peregrine System™ Infusion Catheter in hypertensive subjects in the absence of antihypertensive…
- Trial name
- RADAR (NCT07083765)
- Testing
- Dehydrated Alcohol Injection, USP
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Ablative Solutions, Inc.
Chronic Ulcers, Diabetic Foot Ulcers (DFU)
Case Series of StimLabs Dehydrated Human Umbilical Cord Particulate for Acute and Chronic Wounds
The purpose of this observational case series is to assess the use of Corplex P as a resorbable particulate device used to cover, protect, and provide a moist wound environment when added to the standard of care treatment of…
- Conditions
- Chronic Ulcers, Diabetic Foot Ulcers (DFU), DFU, Ulcer
- Trial name
- NCT07414368
- Testing
- Corplex P is used to cover, protect, and provide a moist wound environment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- StimLabs
Knee Osteoarthritis
Efficacy of Dehydrated Cell and Protein Concentrate Versus Corticosteroid
To compare the efficacy of Ascent injection versus corticosteroid injection in treating knee osteoarthritis.
- Trial name
- NCT03710005
- Testing
- Ascent, Standard
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- StimLabs
Scarring
Amniotic Membrane in Total Knee Replacements to Reduce Scarring
The overall objective of this study is to evaluate the effectiveness of dHACM in reducing scar tissue formation in total knee replacement patients.
- Trial name
- NCT02088567
- Testing
- Total Knee Arthroplasty, Application of dHACM
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- MiMedx Group, Inc.
Pressure Injury
Evaluating the Efficacy of NeoThelium FT in the Treatment of Pressure Injuries
This is a randomized controlled trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in treating pressure injuries.
- Trial name
- NCT06918548
- Testing
- Standard of Care, NeoThelium FT
- Volunteers
- 148 people
- Sponsor
- NuScience Medical Biologics, LLC
Myopia
Dehydration of Omafilcon A Contact Lenses Versus Delefilcon A Contact Lenses
The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.
- Trial name
- NCT02366910
- Testing
- omafilcon A, delefilcon A
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- CooperVision, Inc.
Pressure Injury
Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Chronic Pressure Ulcers
This is a prospective case series evaluating the efficacy and safety of NeoThelium FT Amnion Skin Graft in the Mangement of Chronic Pressure Ulcers
- Trial name
- NCT07158658
- Testing
- NeoThelium FT (HCT/P 361)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- NuScience Medical Biologics, LLC
Diabetic Foot Ulcer (DFU), Ulcer Foot
Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs
The purpose of this study is to evaluate the efficacy of four dehydrated complete human placental membrane, also defined as Cellular, Acellular, Matrix-like Products/skin substitutes, plus SOC versus SOC alone in achieving…
- Conditions
- Diabetic Foot Ulcer (DFU), Ulcer Foot, Diabetic Foot, Foot Ulcer
- Trial name
- CAMPSTIM (NCT06449638)
- Testing
- Standard of Care, Revita, Relese
- Where
- 5 sites in United States
- Volunteers
- 272 people
- Sponsor
- StimLabs
Dehydration
Biomarkers for Noninvasive Assessment of Human Hydration
Low levels of dehydration (the loss of body water corresponding to 2% of the body weight), deteriorate physical and cognitive performance and may also be linked to a number of chronic diseases.
- Trial name
- NCT01507129
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gaia Medical Institute
Dehydration
Using Hydration Monitor to Detect Changes in the Hydration Status Athletes
The study will aim to evaluate the correlation between changes in ultrasound velocity and measures of hydration status including urine specific gravity, plasma and urine osmolality in male and female young adults after undergoing…
- Trial name
- NCT02206581
- Testing
- Hydration Monitor
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Artann Laboratories
Dehydrated, Water-Electrolyte Imbalance, Malnutrition
Explorative Study on a New Device' Ability to Register Hydration Change in Elderly Subjects During Rehabilitation.
Test the ability of continuous measurements from a new sensor patch to set the hydration state in subjects who are malnourished/dehydrated or overhydrated or otherwise not optimally hydrated.
- Trial name
- NCT04937465
- Testing
- No intervention done
- Where
- 6 sites in Norway
- Sponsor
- Mode Sensors AS