Clinical trials: Delayed Onset Muscle Soreness
Delayed Onset Muscle Soreness, DOMS
COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)
The study is designed as a proof of concept, single-center, randomized, double-blind, placebo controlled study to assess the safety and efficacy of Comboprofen (Ibuprofen + Magnesium + Vitamin C) compared to placebo, Ibuprofen…
- Trial name
- NCT03223519
- Testing
- Comboprofen, Ibuprofen, Magnesium
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Spherium Biomed
Pain, Acute
Controlled Study to Assess the Efficacy and Safety of S-Ibuprofen Topical Gel 5% (AP0302) in the Treatment of DOMS
Phase 2 study designed to evaluated analgesic efficacy and safety of S-Ibuprofen Topical Gel 5%
- Trial name
- NCT03852459
- Testing
- S-Ibuprofen, Vehicle
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Aponia Laboratories, Inc.
Delayed Onset Muscle Soreness (DOMS)
PNF Versus Cryotherapy in Delayed Onset Muscle Soreness
This randomized, double-blind, single-center pilot clinical trial evaluated three interventions for delayed onset muscle soreness in the hamstring muscles. Twenty-nine untrained adults were included.
- Trial name
- NCT07624032
- Testing
- Proprioceptive Neuromuscular Facilitation, Local Cryotherapy
- Where
- Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia de Salamanca
Delayed Onset Muscle Soreness (DOMS), Muscle Soreness
Effectiveness of Instrument-Assisted Soft Tissue Mobilization (IASTM) and Myofascial Release in Reducing Delayed Onset Muscle Soreness (DOMS) in the Cervicothoracic Region
The current study is a randomized controlled trail comparing the effectiveness of IASTM and Myofascial Release for individuals with DOMS at cervicothoracic region.
- Conditions
- Delayed Onset Muscle Soreness (DOMS), Muscle Soreness, Myalgia
- Trial name
- COMPARE-DOMS (NCT07609498)
- Testing
- IASTM, MFR
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Green International University
Musculoskeletal Pain, Athletic Injuries
Single Focused Shock Wave in the Release od Delayed Onset Muscle Soreness (DOMS)
The study is a single-center, double blinded, randomized controlled trial aimed to investigate the effects of focused extracorporeal shockwave therapy (fESWT) on Delayed Onset Muscle Soreness (DOMS) of the non-dominant biceps…
- Trial name
- NCT02548208
- Testing
- Verum focused extracorporeal shockwave
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dr. Johannes Fleckenstein
Muscle Soreness, Perceived Recovery
Effect of Wearing a Compression Sock During Running on Muscle Soreness in Distance Runners.
Running is the most popular physical activity worldwide. Although running provides many health benefits, it is often associated with injuries and symptoms such as delayed onset muscle soreness.
- Conditions
- Muscle Soreness, Perceived Recovery, Perceived Exertion, Affective Response
- Trial name
- NCT06225388
- Testing
- Compression socks
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Health Behavior, Muscle Strain, Lower Leg
Effect of Tissue Flossing on Recovery Time After Intense Physical Exercise Causing Delayed Onset Muscle Soreness
The aim of the study is to assess whether soft tissue flossing therapy will alleviate eccentric muscle-destroying influences. Men aged 20-25 will be tested.
- Trial name
- NCT05684315
- Testing
- soft tissue flossing therapy
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Delayed-onset Muscle Soreness, Sleep
Sleep and Delayed-onset Muscle Soreness
There is a need for further experimental research in order to gain a more in-depth understanding of this vicious cycle of pain and sleep disorders.
- Conditions
- Delayed-onset Muscle Soreness, Sleep, Pain
- Trial name
- NCT06699186
- Testing
- Sleep, Non-sleep
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Delayed-Onset Muscle Soreness (DOMS), Exercise-induced Muscle Damage
TENS Versus Foam Rolling for Muscle Recovery After Eccentric Exercise in Elite Female Volleyball Players
Purpose: This study compared two recovery methods-transcutaneous electrical nerve stimulation (TENS) and foam rolling (FR)-for muscle recovery after intense exercise in elite female volleyball players.
- Conditions
- Delayed-Onset Muscle Soreness (DOMS), Exercise-induced Muscle Damage, Muscle Recovery, Athletic Injuries
- Trial name
- TENS-FR-VB (NCT07438197)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Foam Rolling (FR)
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Muscle Soreness, Delayed-onset Muscle Soreness
Effects of ReWin(d) Supplementation on the Recovery of DOMS Induced by Acute Exercice
The study will assess the recovery and performance of young athletes suffering from muscle damage induced by physical exercise. Model by comparing the safety and efficacy of ReWin(d) supplemention during 4 weeks to placebo over…
- Trial name
- NCT03961022
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Natural Origins
Delayed Onset Muscle Soreness (DOMS), Inflammation
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion
The goal of this clinical trial is to learn if applying cold therapy can reduce swelling, inflammation, and pain after physical activity in adults who experience muscle soreness (Delayed Onset Muscle Soreness, or DOMS).
- Conditions
- Delayed Onset Muscle Soreness (DOMS), Inflammation, Muscle Pain, Muscle Damage
- Trial name
- NCT06813690
- Testing
- Cold Therapy with Axanova Cold Hot Pearls Maxi Pack
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Delayed-Onset Muscle Soreness (DOMS)
The Effectiveness of Sustained Heat Treatment on Delayed-Onset Muscle Soreness (DOMS)
This post-market clinical follow-up, open-label, multicenter, randomized, parallel group clinical investigation is designed to investigate the effectiveness, safety, and tolerability of immediate and delayed ThermaCare HeatWraps…
- Trial name
- DOMS (NCT06111118)
- Testing
- ThermaCare HeatWraps
- Where
- 6 sites in Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Muscle Soreness
A Within-subject Study to Evaluate the Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness
This study will assess the analgesic efficacy of DSG 1% compared to placebo in the reduction of the pain associated with DOMS
- Trial name
- NCT02271854
- Testing
- Diclofenac sodium gel 1%
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Novartis
Muscle Tightness
Enhanced External Counterpulsation on Delayed Onset Muscle Soreness
This study will evaluate the effects of Enhanced External Counterpulsation on delayed onset muscle soreness. The primary outcomes will be duration of delayed onset muscle soreness, WBC count, CRP count, CPK count, and pain…
- Trial name
- NCT02175316
- Testing
- Enhanced External Counterpulsation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Delayed Onset Muscle Soreness (DOMS), Exercise-Induced Muscle Soreness
A Study of Mitragynine Formulations for Exercise-Induced Muscle Soreness in Healthy Adults
This Phase II randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, and physical dependence potential of mitragynine-containing formulations after 28 days of use and assess their effects on…
- Trial name
- NCT07809282
- Testing
- SpecioTea, MitraPlex
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Traditional Naturals Research Inc.
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Photobiomodulation on NMES-Induced Muscle Fatigue and Damage
Neuromuscular electrical stimulation (NMES) is effective for strength training and rehabilitation, but non-selective motor unit recruitment often induces rapid fatigue, discomfort, and muscle damage.
- Conditions
- Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS), Muscle Damage, Photobiomodulation (PBM)
- Trial name
- NCT07790016
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Exercise Induced Muscle Damage
Indirect Biomarkers and Exercise Induced Muscle Damage
The purpose of this study is to investigate the magnitude of changes in biomarkers of exercise-induced muscle damage following an acute bout of eccentric exercise of the knee extensors performed on an isokinetic dynamometer.
- Trial name
- NCT07503860
- Testing
- Eccentric Exercise
- Where
- Greece
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vassilis Paschalis
Pain
Mirthful Laughter and Muscle Soreness / Pain
The purpose of this study is first to investigate the effect of a controlled intervention with a comedy video on pain tolerance in a social setting while quantitatively measuring laughter in a young healthy population…
- Trial name
- NCT02896075
- Testing
- 30 Minute Comedy Video, 30 Minute Documentary Video
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Delayed Onset Muscle Soreness
Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery
Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS).
- Trial name
- NCT06815367
- Testing
- Pneumatic Compression, Blood Flow Restriction
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise
This randomized, parallel, placebo-controlled, double-blind clinical trial will evaluate the effects of low-intensity therapeutic ultrasound on muscle recovery after a fatiguing handgrip exercise protocol in healthy adults.
- Trial name
- NCT07871942
- Testing
- Pulsed Low-Intensity Therapeutic Ultrasound
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria