Clinical trials: Delirium, completed
Delirium
Delirium Reduction by Volatile Anesthesia in Cardiac Surgery
Parallel group, prospective, randomized, controlled, single-blinded trial. The aim of our study is to test the hypothesis that volatile anesthesia would reduce the incidence of early postoperative delirium in patients undergoing…
- Trial name
- DELICATE (NCT03729011)
- Testing
- Volatile agent, Propofol
- Where
- 5 sites in Russia
- Volunteers
- 405 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Delirium, Cytochrome P-450 Enzyme System
The Impact of Cytochrome P450 Abnormalities in Patients With Delirium.
Objectives: 1. To examine whether patients with delirium have higher prevalence of cytochrome-P450 abnormalities compared to patients without delirium. 2.
- Trial name
- NCT03829670
- Testing
- Cytochrome P450 test
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Delirium in Old Age
REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant
This research study will evaluate the effectiveness of postoperative administration of a drug called suvorexant, to improve postoperative sleep and decrease the severity of delirium (serious confusion) in adults 65 years and…
- Trial name
- REPOSE (NCT05733286)
- Testing
- Suvorexant 20 mg
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Duke University
Emergence Agitation
Effect of Induction Method in Post Operative Agitation
To compare the effect of two different induction method; mask ventilation and intravenous cannulation on emergence agitation on pediatric adenotonsillectomy
- Trial name
- NCT03252405
- Testing
- mask ventilation, intravenous cannulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Anesthesia, General
Recorded Maternal Voice on the Emergence of General Anesthesia on Pediatric Patients
Mother spend a large amount of time with their children. It is assumed that mother contributes to their neurological development not only with visual stimuli, but also with auditory stimuli.
- Trial name
- Maternal voice (NCT02955680)
- Testing
- recorded maternal voice, recorded stranger's voice
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Daegu Catholic University Medical Center
Postoperative Delirium
Machine Learning Algorithm for Predicting Postoperative Delirium in Elderly Patients After Thoracic Surgery
Postoperative delirium (POD) is a common and severe complication in patients undergoing major surgery, especially in the elderly.
- Trial name
- POD (NCT06226480)
- Where
- China
- Volunteers
- 3,967 people
- Sponsor
- Affiliated Hospital of Nantong University
Critical Illness, Physiological Stress
Trial to Evaluate the Effects of Sound Modulation on Critically Ill Patients
The goal of the project is to determine the effects of noise masking and noise reduction on stress related physiological parameters in critically ill patients admitted to the intensive care unit.
- Conditions
- Critical Illness, Physiological Stress, Delirium, Sleep Deprivation
- Trial name
- SMART (NCT03019133)
- Testing
- Sound reduction, Sound masking
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brian Gehlbach
Emergence From Anesthesia, Mechanical Ventilation
Controlled Ventilation During Anesthetic Emergence
Absolutely - for a ClinicalTrials.gov-style Brief Summary, I'd keep it simple and patient-friendly like your example: The goal of this clinical trial is to learn whether maintaining controlled mechanical ventilation during…
- Trial name
- NCT07853547
- Testing
- Controlled/Full-Support Mechanical Ventilation During Emergence
- Where
- Saudi Arabia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Hip Fractures
Deep Neuromuscular Block on Cytokines Release and Postoperative Delirium
The purpose of the study is to determine the relationship between the degree of neuromuscular block, the release of cytokines and clinical outcomes in elderly patients undergoing orthopedic surgery.
- Trial name
- NCT02507609
- Testing
- Moderate neuromuscular blockade, Deep neuromuscular blockade
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Konkuk University Medical Center
Postoperative Delirium, Postoperative Stroke
Postoperative Stroke and Epiaortic Ultrasound in CABG
This study aims to investigate the incidence of postoperative stroke and neurocognitive impairment in patients undergoing coronary artery bypass grafting (CABG), with or without the use of epi-aortic ultrasound (EAU).
- Trial name
- EAU and POCD (NCT07101393)
- Testing
- Intraoperative Epiaortic Ultrasound (EAU)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ataturk University
Delirium, Health Knowledge, Attitudes, Practice
Nurses' Knowledge, Barriers and Practices in the Assessment of Delirium in the Intensive Care Unit
Delirium in intensive care patients is a complication associated with many adverse consequences. It negatively affects patient outcomes, is an independent predictor of mortality, prolongs intensive care unit (ICU) stay and causes…
- Conditions
- Delirium, Health Knowledge, Attitudes, Practice, Critical Care Nursing
- Trial name
- NCT05384964
- Testing
- Questionnaire
- Where
- Poland
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Delirium on Emergence
Post Extubation Delirium and End-tidal Sevoflurane Concentration
The purpose of this study is to determine whether the incidence of emergence delirium will be reduced when end-tidal concentration of sevoflurane decreases.
- Trial name
- NCT02489734
- Testing
- sevoflurane
- Volunteers
- 109 people
- Sponsor
- Children's Hospital of Fudan University
Delirium, Cognition Disorders
The MIND Study: Modifying the INcidence of Delirium
Delirium is associated with increased risk of death, prolonged stay, higher cost of care, and likely long-term brain deficits in survivors.
- Trial name
- NCT00096863
- Testing
- Ziprasidone, Haloperidol
- Where
- 5 sites in United States
- Volunteers
- 102 people
- Sponsor
- Vanderbilt University
Delirium
Assessment of Postoperative Delirium With CAM ICU Score in Patients Treated With Serotoninergic Reuptake (SSRI) Inhibitors and Undergoing Intervention of Heart Surgery on Pump
The study aims to observe the presence of postoperative delirium in patients undergoing elective cardiac surgery, without changing the pharmacological prescriptions of the enrolled patients and the procedures carried out by…
- Trial name
- DeCAMS-ON (NCT05089097)
- Testing
- evaluation of delirium with CAM-ICU Score
- Where
- Italy
- Volunteers
- 152 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Pregabalin, Dexmedetomidine
Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery
The aim of this study is to compare the effect of perioperative administration of pregabalin versus dexmedetomidine on the prevalence and lasting duration of delirium in elderly patients after cardiac surgery.
- Conditions
- Pregabalin, Dexmedetomidine, Delirium
- Trial name
- NCT05640479
- Testing
- Pregabalin, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Delirium, Dementia
Validating Studies to Assess the Diagnostic Accuracy of a Software Application for Detection and Monitoring of Attentional Deficits in Delirium
The study has two phases: Phase B and Phase C. The purpose of the Phase B study is to determine the performance (sensitivity and specificity) of a smartphone application (DelApp) to identify delirium in the whole inpatient…
- Trial name
- NCT02590796
- Testing
- No intervention given to participants
- Where
- 2 sites in United Kingdom
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Sleep Deprivation, Delirium
Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients?
Specific Aims 1. Establish the feasibility of larger trial by implementing a sleep protocol in the ICU at 2 different sites. Specifically will be estimating the recruitment rates of patients and the compliance with both…
- Trial name
- SKY-DEX (NCT01791296)
- Testing
- Dexmedetomidine
- Where
- 2 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Strabismus, Delirium on Emergence
Efficacy of Single-Shot Dexmedetomidine Versus Placebo in Preventing Pediatric Emergence Delirium in Strabismus Surgery
This study is trying to see if using precedex pre-operatively prevents emergence delirium in pediatric (ages 1-7) patients undergoing strabismus surgery.
- Conditions
- Strabismus, Delirium on Emergence, Pediatric Disorders
- Trial name
- NCT01901588
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- NYU Langone Health
Delirium
The Effect of Ramelteon on Delirium and Sleep in Patients Admitted to the ICU
Delirium is a disturbance in attention and awareness that occurs over a short period of time. Delirium is common in critically ill patients, and poor sleep quality in the intensive care unit (ICU) often worsens delirium.
- Trial name
- NCT03931070
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Rhode Island Hospital
Delirium, Lumbar Radiculopathy
Shaping Anesthetic Techniques to Reduce Post-operative Delirium
The purpose of this study is to determine if light sedation with spinal anesthesia reduces the incidence of delirium compared to receiving general anesthesia during spinal surgery in older adults.
- Conditions
- Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
- Trial name
- SHARP (NCT03133845)
- Testing
- Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Johns Hopkins University