Clinical trials: Delirium, completed
Agitation, Excited Delirium
Stress Biomarkers Among Patients Undergoing Treatment for Excited Delirium and Severe Pain in the Emergency Department
The purpose of this project is to determine the levels of stress biomarkers associated with severe pain, agitation from intoxication or psychosis, and excited delirium at various levels of the disease in order to compare them to…
- Conditions
- Agitation, Excited Delirium, Pain
- Trial name
- Agitation (NCT01747824)
- Where
- United States
- Volunteers
- 1,322 people
- Sponsor
- Hennepin Healthcare Research Institute
Delirium, Postoperative Cognitive Dysfunction
Prevention of Early Postoperative Decline
The purpose of this trial is to determine whether using a brain training program in the time leading up to as well as after heart surgery will reduce confusion and cognitive loss that can occur after surgery.
- Trial name
- PEaPoD (NCT02908464)
- Testing
- Lumosity
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Beth Israel Deaconess Medical Center
Delirium
Prediction of PACU Delirium Using EEG - German Validation Study
Aim of this observational study is to investigate whether frontal electroencephalogram analysis is able to predict increased risk for PACU delirium.
- Trial name
- PACUD-EEG (NCT03287401)
- Testing
- Electroencephalography
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technical University of Munich
Cognitive Dysfunction, Cognitive Disorder, Delirium - Postoperative
the Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium
In this study, the cognitive status of the patients in the preoperative period was taken into consideration and the development of delirium after the surgery was investigated. There is no harm to the patient.
- Trial name
- NCT06597812
- Testing
- Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Amasya University
Anesthesia
Anesthesia of Endolaryngeal Laser Surgery and Perioperative Side Effects
Investigators analyze the anesthesia of the endolaryngeal laser surgery in patients with smoking with or without monitoring of depth of anesthesia (bispectral index)
- Trial name
- NCT04903483
- Testing
- bispectral index monitoring
- Where
- 2 sites in Hungary
- Volunteers
- 50 people
- Sponsor
- University of Pecs
Delirium
Analysis of Medication Data With the ApoMining-Database
The primary objective of this study is to analyse medication data from the BioCog Study with the ApoMining-Database and to determine the positive and negative predictive value from the ApoMining-Database for prediction of…
- Trial name
- NCT03528798
- Where
- Germany
- Volunteers
- 349 people
- Sponsor
- Charite University, Berlin, Germany
Delirium
Quetiapine in Prevention of Delirium
The aim is to study the effectiveness of Quetiapine in preventing delirium in the elderly patients with multiple risks for delirium.
- Trial name
- NCT05793632
- Testing
- Quetiapine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Cognitive Impairment, Frail Elderly Syndrome
Preoperative Cognitive Screening in Older Spinal Surgical Patients
The objectives of this study are to determine whether identifying patients with baseline cognitive deficits or frailty predict postoperative delirium.
- Trial name
- NCT02922634
- Testing
- Mini Cog
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Post-cardiac Surgery
Dexmedetomidine Enhancing the Recovery After Cardiac Surgery
Enhanced Recovery After Surgery (ERAS) aims to facilitate a quicker and smoother recovery period following surgical procedures. The implementation of these protocols may lead to patients returning to their daily activities…
- Trial name
- NCT06907277
- Testing
- Dexmedetomidine, Fentanyl, Lidocain
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
Aged, Operative
Dexmedetomidine and 5-year Outcome in Elderly Patients After Surgery
Delirium is a frequent postoperative complication. Its occurrence is associated with worse long-term outcomes. In a previous randomized controlled trial, prophylactic low-dose dexmedetomidine infusion during the early…
- Conditions
- Aged, Operative, Delirium, Dexmedetomidine
- Trial name
- NCT03436472
- Testing
- dexmedetomidine
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Peking University First Hospital
Intensive Care, Surgical, Anesthesia, General
Nociception Level Index as Monitorization of Pain at the Intensive Care
The aim of our study is to evaluate the effectiveness of a nociception monitor in providing adequate postoperative analgesia for patients needing critical care after surgery.
- Trial name
- NCT05762666
- Testing
- nociception level index monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Emergence Agitation, Anesthesia Recovery
Bispectral Index, Suppression Rate and Emergence Agitation in Spine Surgeries
Emergence agitation; generally refers to a situation that may occur after a surgical intervention or anesthesia. This situation describes the irritability and agitation of the patient during the recovery process and the period of…
- Conditions
- Emergence Agitation, Anesthesia Recovery, Bispectral Index Monitor
- Trial name
- NCT06334939
- Testing
- Bispectral Index Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Ahmet Yuksek
Delirium
Peri-operative Monitoring of Cerebral Oxygenation and the Onset of Delirium in Patients Undergoing Cardiac Surgery
Delirium is an acute brain syndrome characterized by a disturbance in consciousness accompanied by periods of inattention and changes in cognition.
- Trial name
- ICARUS (NCT02532530)
- Testing
- Near-Infrared Spectroscopy (NIRS)
- Where
- Belgium
- Volunteers
- 103 people
- Sponsor
- Hasselt University
Dementia, Dementia, Vascular
Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers
Aim 1. To compare across three hospital sites the effects on health and cost outcomes observed by the following three interventions, each designed to enhance adaptation and improve outcomes of hospitalized cognitively impaired…
- Conditions
- Dementia, Dementia, Vascular, Alzheimer Disease, Delirium, Dementia, Amnestic, Cognitive Disorders
- Trial name
- NCT00294307
- Testing
- Augmented Standard Care (ASC), Resource Nurse Care (RNC), Advanced Practice Nurse Care (APNC)
- Where
- 3 sites in United States
- Volunteers
- 814 people
- Sponsor
- University of Pennsylvania
Caudal Block, Pediatric Urologic Surgeries
Comparison of Caudal Block Combined With General Anesthesia and Penile Block and Intravenous Fentanyl in Pediatric Surgeries
Urogenital surgery is one of the most frequently performed surgical procedures in the pediatric patient population. There is no consensus on which analgesic method is most effective for pain control in these patients.
- Conditions
- Caudal Block, Pediatric Urologic Surgeries, Fentanyl, Pediatric Delirium
- Trial name
- NCT06862271
- Testing
- Group 1 ( Caudal block group ), Group 2 (Penile block and IV Fentanyl group)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Miray Gözde Özdemir
Pediatric Delirium
Prospective Prevalence and Validation Study of Pediatric Intensive Care Delirium.
Pediatric delirium (PD) is a poorly investigated clinical problem that needs to be further explored in a Danish context. Children are at risk of discomfort and suffering if they experience delirium.
- Trial name
- NCT04774211
- Testing
- SOS-PD
- Where
- Denmark
- Volunteers
- 141 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Delirium in the Intensive Care Unit
Nurse-Led Implementation of the ABCDEF Bundle
This study evaluated the effectiveness of a nurse-led implementation of the ABCDEF bundle, an evidence-based, interprofessional care framework, in the prevention and management of delirium among Intensive Care Unit (ICU)…
- Trial name
- NCT07054268
- Testing
- Nurse-Led ABCDEF Bundle Implementation
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Helwan University
Post-Operative Delirium, Hip Fracture
Post-operative Haloperidol Versus Placebo for Prevention of Post-operative Delirium After Acute Hip Surgery
In this study the investigators want to determine if treatment with haloperidol direct post-operatively after acute hip surgery in high risk patients protects against developing a post-operative delirium.
- Trial name
- NCT00250237
- Testing
- Haloperidol
- Where
- Netherlands
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Bronovo Hospital
Post-Operative Delirium
A Study to Evaluate ICU Simulation Experience in the Cardiothoracic Surgical Population to Reduce Post-operative Delirium
The purpose of this study is to evaluate the effect of a pre-ICU admission virtual reality ICU simulation on post-operative delirium in the elective cardiothoracic surgical population while in the intensive care unit.
- Trial name
- NCT05159648
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Mayo Clinic
Delirium, Cognitive Impairment
Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)
There is lack of attention to preoperative cognitive function and delirium in elderly who underwent surgery. The investigators are investigating different tools that can help to screen for cognitive dysfunction and delirium in…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Dysfunction, Cognitive Dysfunction, Postoperative
- Trial name
- NCT05209555
- Testing
- MoCA, BAMCOG, DeltaScan
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven